(Q36977690)

English

Core pathway mutations induce de-differentiation of murine astrocytes into glioblastoma stem cells that are sensitive to radiation but resistant to temozolomide.

scientific article published on 28 January 2016

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6 March 2020

Core pathway mutations induce de-differentiation of murine astrocytes into glioblastoma stem cells that are sensitive to radiation but resistant to temozolomide (English)

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6 March 2020

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6 March 2020

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6 March 2020

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Mark Vitucci

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6 March 2020

Ewan Robert West McNeill

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Robert S McNeill

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6 March 2020

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Ryan E Bash

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6 March 2020

Andrea M Werneke

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Andrea M Werneke

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6 March 2020

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Kristen K White

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6 March 2020

author name string

Jeremy M Simon

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6 March 2020

Lauren Huey

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6 March 2020

Matthew G Ewend

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6 March 2020

Jing Wu

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6 March 2020

publication date

28 January 2016

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6 March 2020

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6 March 2020

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6 March 2020

7

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6 March 2020

962-973

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6 March 2020

Activated k-ras, but not h-ras or N-ras, regulates brain neural stem cell proliferation in a raf/rb-dependent manner

1 reference

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In vivo radiation response of proneural glioma characterized by protective p53 transcriptional program and proneural-mesenchymal shift.

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The somatic genomic landscape of glioblastoma

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Cooperativity between MAPK and PI3K signaling activation is required for glioblastoma pathogenesis

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Dedifferentiation of neurons and astrocytes by oncogenes can induce gliomas in mice

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The retinoblastoma tumor suppressor and stem cell biology

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Distinct molecular mechanisms of acquired resistance to temozolomide in glioblastoma cells

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MGMT-independent temozolomide resistance in pediatric glioblastoma cells associated with a PI3-kinase-mediated HOX/stem cell gene signature

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Reversing HOXA9 oncogene activation by PI3K inhibition: epigenetic mechanism and prognostic significance in human glioblastoma

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p53 and Pten control neural and glioma stem/progenitor cell renewal and differentiation

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1 reference

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21 January 2018

Identifiers

10.1093/NEUONC/NOV321

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Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26826202%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

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Europe PubMed Central

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6 March 2020

1 reference

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6 March 2020

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