(Q36997273)

17 August 2017

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title

T lymphocytes in Sjögren's syndrome: contributors to and regulators of pathophysiology (English)

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17 August 2017

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2

Niki M Moutsopoulos

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17 August 2017

3

Sharon M Wahl

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17 August 2017

Gikas E Katsifis

1

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17 August 2017

publication date

1 June 2007

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Clinical Reviews in Allergy & Immunology

17 August 2017

published in

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17 August 2017

volume

32

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17 August 2017

issue

3

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17 August 2017

page(s)

252-264

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Functional expression of a costimulatory B7.2 (CD86) protein on human salivary gland epithelial cells that interacts with the CD28 receptor, but has reduced binding to CTLA4.

17 August 2017

cites work

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Crossref

https://api.crossref.org/works/10.1007%2FS12016-007-8011-8

CD4+CD25bright regulatory T cells actively regulate inflammation in the joints of patients with the remitting form of juvenile idiopathic arthritis.

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS12016-007-8011-8

Lacrimal gland inflammation is responsible for ocular pathology in TGF-beta 1 null mice

21 January 2018

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12 December 2020

Acquisition of lymphokine-producing phenotype by CD4+ T cells

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12 December 2020

Distinct effects of T-bet in TH1 lineage commitment and IFN-gamma production in CD4 and CD8 T cells

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12 December 2020

The role of 2 FOXP3 isoforms in the generation of human CD4+ Tregs.

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12 December 2020

Divergent pro- and antiinflammatory roles for IL-23 and IL-12 in joint autoimmune inflammation

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12 December 2020

Programmed cell death of peripheral blood B cells determined by laser scanning cytometry in Sjögren's syndrome with a special emphasis on BAFF

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12 December 2020

CD4 cytotoxic and dendritic cells in the immunopathologic lesion of Sjögren's syndrome

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12 December 2020

Functional roles of NKT cell in the immune system

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12 December 2020

The kiss of death: interrupted by NK-cell close encounters of another kind

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12 December 2020

Intracellular trafficking and surface expression of SS-A (Ro), SS-B (La), poly(ADP-ribose) polymerase and alpha-fodrin autoantigens during apoptosis in human salivary gland cells induced by tumour necrosis factor-alpha

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12 December 2020

A dual role for interferon-gamma in the pathogenesis of Sjogren's syndrome-like autoimmune exocrinopathy in the nonobese diabetic mouse.

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12 December 2020

Activation of IFN pathways and plasmacytoid dendritic cell recruitment in target organs of primary Sjögren's syndrome

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12 December 2020

Distinct profiles of Sjögren's syndrome patients with ectopic salivary gland germinal centers revealed by serum cytokines and BAFF

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12 December 2020

TGF-beta: how tolerant can it be?

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12 December 2020

Role of CD8+ T cells in murine experimental allergic encephalomyelitis

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12 December 2020

Suppression of collagen-induced arthritis by natural killer T cell activation with OCH, a sphingosine-truncated analog of alpha-galactosylceramide

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12 December 2020

Etanercept in Sjögren's syndrome: a twelve-week randomized, double-blind, placebo-controlled pilot clinical trial

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12 December 2020

Involvement of the interferon-gamma-induced T cell-attracting chemokines, interferon-gamma-inducible 10-kd protein (CXCL10) and monokine induced by interferon-gamma (CXCL9), in the salivary gland lesions of patients with Sjögren's syndrome

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12 December 2020

Lymphocyte subsets of the peripheral blood in Sjögren's syndrome and rheumatoid arthritis.

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12 December 2020

Conversion of peripheral CD4+CD25- naive T cells to CD4+CD25+ regulatory T cells by TGF-beta induction of transcription factor Foxp3

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12 December 2020

Isolation and functional characterization of regulatory CD25brightCD4+ T cells from the target organ of patients with rheumatoid arthritis

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12 December 2020

The immune system. First of two parts

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12 December 2020

Detection of Epstein-Barr virus-associated antigens and DNA in salivary gland biopsies from patients with Sjogren's syndrome

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12 December 2020

The BAFF/APRIL system: an important player in systemic rheumatic diseases

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12 December 2020

A central role for central tolerance

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12 December 2020

TGF-beta: the missing link in CD4+CD25+ regulatory T cell-mediated immunosuppression

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12 December 2020

Impairment of CD4(+)CD25(+) regulatory T-cells in autoimmune liver disease.

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12 December 2020

Increased thymic mass and circulating naive CD4 T cells in HIV-1-infected adults treated with growth hormone.

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12 December 2020

Cell contact-dependent immunosuppression by CD4(+)CD25(+) regulatory T cells is mediated by cell surface-bound transforming growth factor beta

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12 December 2020

TGFbeta in the context of an inflammatory cytokine milieu supports de novo differentiation of IL-17-producing T cells

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12 December 2020

X-linked neonatal diabetes mellitus, enteropathy and endocrinopathy syndrome is the human equivalent of mouse scurfy

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12 December 2020

Foxp3 programs the development and function of CD4+CD25+ regulatory T cells

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12 December 2020

Single cell analysis of T cells infiltrating labial salivary glands from patients with Sjögren's syndrome

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12 December 2020

B cell-activating factor of the tumor necrosis factor family (BAFF) is expressed under stimulation by interferon in salivary gland epithelial cells in primary Sjögren's syndrome

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12 December 2020

Regulatory T cells in spontaneous autoimmune encephalomyelitis

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12 December 2020

The Th1/Th2 cytokine balance changes with the progress of the immunopathological lesion of Sjogren's syndrome

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12 December 2020

Salivary gland expression of transforming growth factor beta isoforms in Sjogren's syndrome and benign lymphoepithelial lesions

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12 December 2020

The immune system evolved to discriminate infectious nonself from noninfectious self

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12 December 2020

Circulating CD4+CD25+ T regulatory cells are not altered in multiple sclerosis and unaffected by disease-modulating drugs

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12 December 2020

Association of BAFF/BLyS overexpression and altered B cell differentiation with Sjögren's syndrome

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12 December 2020

Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells

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12 December 2020

Lymphocyte migration to inflamed lacrimal glands is mediated by vascular cell adhesion molecule-1/alpha(4)beta(1) integrin, peripheral node addressin/l-selectin, and lymphocyte function-associated antigen-1 adhesion pathways

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12 December 2020

CD4+CD25+ regulatory T cells inhibit natural killer cell functions in a transforming growth factor-beta-dependent manner

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12 December 2020

Targeting B lymphocyte stimulator in systemic lupus erythematosus and other autoimmune rheumatic disorders

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12 December 2020

Tumor necrosis factor inhibitor gene expression suppresses lacrimal gland immunopathology in a rabbit model of autoimmune dacryoadenitis

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12 December 2020

Transforming growth factor-beta-induced regulatory T cells referee inflammatory and autoimmune diseases

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12 December 2020

CD40, CD154, Bax and Bcl-2 Expression in Sjogren's Syndrome Salivary Glands: a Putative Anti-Apoptotic Role During its Effector Phases

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12 December 2020

TH1 and TH2 cells: different patterns of lymphokine secretion lead to different functional properties

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12 December 2020

Analysis of transforming growth factor beta and other cytokines in autoimmune exocrinopathy (Sjögren's syndrome)

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12 December 2020

CD4+CD25bright T cells in human intestinal lamina propria as regulatory cells

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12 December 2020

CTLA-4-mediated inhibition in regulation of T cell responses: mechanisms and manipulation in tumor immunotherapy

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12 December 2020

An overview of regulatory T cells

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12 December 2020

Circulating levels of Th1/Th2 cytokines in patients with primary Sjögren's syndrome: correlation with clinical and immunological features

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12 December 2020

Immunohistological analysis of tumour growth factor beta 1 expression in normal and inflamed salivary glands

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12 December 2020

HLA class I and II, interferon, interleukin 2, and the interleukin 2 receptor expression on labial biopsy specimens from patients with Sjögren's syndrome

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12 December 2020

HLA-DR expression by labial minor salivary gland tissues in Sjögren's syndrome

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12 December 2020

Mechanism of transforming growth factor beta-induced inhibition of T helper type 1 differentiation

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12 December 2020

The immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) is caused by mutations of FOXP3

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12 December 2020

Suppression of tumor necrosis factor alpha-induced matrix metalloproteinase 9 production by the introduction of a super-repressor form of inhibitor of nuclear factor kappaBalpha complementary DNA into immortalized human salivary gland acinar cells.

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12 December 2020

TGF-beta: the perpetrator of immune suppression by regulatory T cells and suicidal T cells

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12 December 2020

CD4+ CD25+ T cells with the phenotypic and functional characteristics of regulatory T cells are enriched in the synovial fluid of patients with rheumatoid arthritis

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12 December 2020

Activated self-MHC-reactive T cells have the cytokine phenotype of Th3/T regulatory cell 1 T cells

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12 December 2020

Expression of BAFF (BLyS) in T cells infiltrating labial salivary glands from patients with Sjögren's syndrome

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12 December 2020

RETRACTED: Infliximab in patients with primary Sjögren's syndrome: a pilot study

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12 December 2020

CD1: antigen presentation and T cell function

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12 December 2020

Type I interferons (alpha/beta) in immunity and autoimmunity

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12 December 2020

Regulatory T cells in autoimmmunity*.

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12 December 2020

T cells bearing gamma/delta T cell receptor and their expression of activation antigen in peripheral blood from patients with Sjögren's syndrome

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12 December 2020

Identification and functional characterization of human CD4(+)CD25(+) T cells with regulatory properties isolated from peripheral blood

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12 December 2020

Regulatory/suppressor T cells in health and disease

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12 December 2020

Cutting edge: CD4+CD25+ regulatory T cells suppress antigen-specific autoreactive immune responses and central nervous system inflammation during active experimental autoimmune encephalomyelitis

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12 December 2020

Abrogation of TGFbeta signaling in T cells leads to spontaneous T cell differentiation and autoimmune disease

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12 December 2020

Immunologic self-tolerance maintained by CD25(+)CD4(+) regulatory T cells constitutively expressing cytotoxic T lymphocyte-associated antigen 4.

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12 December 2020

Central tolerance: learning self-control in the thymus

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12 December 2020

T cell receptor repertoire in B cell lymphoproliferative lesions in primary Sjögren's syndrome

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12 December 2020

CD4+CD25+ Regulatory T Cells Cure Murine Colitis: The Role of IL-10, TGF-β, and CTLA4

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12 December 2020

Regulatory T cell clones induced by oral tolerance: suppression of autoimmune encephalomyelitis

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12 December 2020

Naturally arising Foxp3-expressing CD25+CD4+ regulatory T cells in immunological tolerance to self and non-self

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12 December 2020

"Lymphoid" chemokine messenger RNA expression by epithelial cells in the chronic inflammatory lesion of the salivary glands of Sjögren's syndrome patients: possible participation in lymphoid structure formation

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12 December 2020

Disruption of a new forkhead/winged-helix protein, scurfin, results in the fatal lymphoproliferative disorder of the scurfy mouse

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12 December 2020

TNF downmodulates the function of human CD4+CD25hi T-regulatory cells

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12 December 2020

Evidence for coxsackievirus infection in primary Sjögren's syndrome

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12 December 2020

Targeted disruption of the mouse transforming growth factor-beta 1 gene results in multifocal inflammatory disease

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12 December 2020

CD4 CD25high regulatory T cells are not impaired in patients with primary Sjögren's syndrome

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12 December 2020

An essential role for Scurfin in CD4+CD25+ T regulatory cells

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12 December 2020

Disruption of T cell homeostasis in mice expressing a T cell-specific dominant negative transforming growth factor beta II receptor

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12 December 2020

Chemokine expression and leucocyte infiltration in Sjögren's syndrome

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12 December 2020

Increased salivary interleukin-6 levels in patients with primary Sjögren's syndrome

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12 December 2020

Current issues in the diagnosis and treatment of Sjögren's syndrome

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12 December 2020

Interleukin-10 levels increase in cutaneous biopsies of patients undergoing wasp venom immunotherapy.

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12 December 2020

CD28/B7 system of T cell costimulation

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12 December 2020

Helper T cell differentiation enters a new era: le roi est mort; vive le roi!

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12 December 2020

Prominent adverse effects of thalidomide in primary Sjögren's syndrome

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12 December 2020

T cell subpopulations in the labial minor salivary gland histopathologic lesion of Sjögren's syndrome

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12 December 2020

The level of BLyS (BAFF) correlates with the titre of autoantibodies in human Sjögren's syndrome

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12 December 2020

Cytokine mRNA expression in salivary gland biopsies of Sjögren's syndrome

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12 December 2020

Cross-regulation of TNF and IFN-alpha in autoimmune diseases

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12 December 2020

On the ontogeny and physiology of regulatory T cells

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12 December 2020

Control of T-cell activation by CD4+ CD25+ suppressor T cells

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12 December 2020

Glandular and extraglandular expression of costimulatory molecules in patients with Sjögren's syndrome

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12 December 2020

Peripheral blood but not synovial fluid natural killer T cells are biased towards a Th1-like phenotype in rheumatoid arthritis

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12 December 2020

Levels of peripheral T cell tolerance induced by different doses of tolerogen

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12 December 2020

Cytokine and adhesion molecule expression in the minor salivary glands of patients with Sjögren's syndrome and chronic sialoadenitis.

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12 December 2020

Antigen-dependent proliferation of CD4+ CD25+ regulatory T cells in vivo

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12 December 2020

Regulatory T cells: key controllers of immunologic self-tolerance

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12 December 2020

IL-23 drives a pathogenic T cell population that induces autoimmune inflammation

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12 December 2020

Immune effects of therapy with Adalimumab in patients with rheumatoid arthritis

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12 December 2020

Differential regulation of murine T lymphocyte subsets

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12 December 2020

Immunologically privileged sites

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12 December 2020

Fas and Fas ligand expression in the salivary glands of patients with primary Sjögren's syndrome.

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12 December 2020

Murine models of Sjögren's syndrome

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12 December 2020

Histopathological and immunohistochemical analysis of lymphoid follicles in labial salivary glands in primary and secondary Sjögren's syndrome

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12 December 2020

Increased frequency of cells secreting interleukin-6 and interleukin-10 in peripheral blood of patients with primary Sjögren's syndrome

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12 December 2020

T cell receptor expression in Sjögren's syndrome

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12 December 2020

Apoptosis-new clues to the pathogenesis of Sjögren's syndrome?

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12 December 2020

Detection of the tax gene of HTLV-I in labial salivary glands from patients with Sjögren's syndrome and other diseases of the oral cavity.

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12 December 2020

Control of regulatory T cell development by the transcription factor Foxp3

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12 December 2020

Transforming growth factor beta: the good, the bad, and the ugly

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12 December 2020

Alloantigen specific CD8+CD28- FOXP3+ T suppressor cells induce ILT3+ ILT4+ tolerogenic endothelial cells, inhibiting alloreactivity

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12 December 2020

The lineage decisions of helper T cells

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12 December 2020

Cytokine messenger RNA expression in the labial salivary glands of patients with Sjögren's syndrome

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12 December 2020

Scurfin (FOXP3) acts as a repressor of transcription and regulates T cell activation

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12 December 2020

IL‐10 and TGF‐β cooperate in the regulatory T cell response to mucosal allergens in normal immunity and specific immunotherapy

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12 December 2020

In vivo dynamics of antigen-specific regulatory T cells not predicted from behavior in vitro

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12 December 2020

CD4+CD25high regulatory T cells in human autoimmune diabetes

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12 December 2020

Less mortality but more relapses in experimental allergic encephalomyelitis in CD8-/- mice

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12 December 2020

Immunohistochemistry of minor salivary gland biopsy specimens from patients with Sjogren's syndrome with and without hepatitis C virus infection

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12 December 2020

Expression of TNF-related apoptosis inducing ligand (TRAIL) on infiltrating cells and of TRAIL receptors on salivary glands in patients with Sjögren's syndrome

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12 December 2020

Human allograft acceptance is associated with immune regulation

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12 December 2020

The role of the combination of IL-2 and TGF-β or IL-10 in the generation and function of CD4+ CD25+ and CD8+regulatory T cell subsets

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12 December 2020

CD25brightCD4+ regulatory T cells are enriched in inflamed joints of patients with chronic rheumatic disease

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12 December 2020

Type 1 T regulatory cells.

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12 December 2020

Transforming growth factor beta 1 null mutation in mice causes excessive inflammatory response and early death

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12 December 2020

B7/CD28 costimulation is essential for the homeostasis of the CD4+CD25+ immunoregulatory T cells that control autoimmune diabetes

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12 December 2020

Transforming growth factor-beta induces development of the T(H)17 lineage

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12 December 2020

CD25+CD4+ regulatory T cells in patients with Kawasaki disease.

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12 December 2020

Local adeno-associated virus-mediated interleukin 10 gene transfer has disease-modifying effects in a murine model of Sjögren's syndrome

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12 December 2020

Attenuated apoptosis of B cell activating factor-expressing cells in primary Sjögren's syndrome

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12 December 2020

Infection, autoimmunity, and glycolipids: T cells detect microbes through self-recognition

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12 December 2020

Association of CXCL13 and CCL21 expression with the progressive organization of lymphoid-like structures in Sjögren's syndrome

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12 December 2020

Production of interleukin 2 (IL 2) by salivary gland lymphocytes in Sjögren's syndrome. Detection of reactive cells by using antibody directed to synthetic peptides of IL 2

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12 December 2020

Etanercept in the treatment of patients with primary Sjögren's syndrome: a pilot study

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12 December 2020

Compromised function of regulatory T cells in rheumatoid arthritis and reversal by anti-TNFalpha therapy

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12 December 2020

Oral delivery of group A streptococcal cell walls augments circulating TGF-beta and suppresses streptococcal cell wall arthritis

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12 December 2020

Crucial role of FOXP3 in the development and function of human CD25+CD4+ regulatory T cells

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12 December 2020

Treatment with anti-CD86 costimulatory molecule prevents the autoimmune lesions in murine Sjögren's syndrome (SS) through up-regulated Th2 response

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12 December 2020

The role of apoptosis in the initiation of the autoimmune response in Sjögren's syndrome

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12 December 2020

The role of B7-1/B7-2:CD28/CLTA-4 pathways in the prevention of anergy, induction of productive immunity and down-regulation of the immune response

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12 December 2020

Mouse CD1-specific NK1 T cells: development, specificity, and function

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12 December 2020

Aberrant expression of B-lymphocyte stimulator by B chronic lymphocytic leukemia cells: a mechanism for survival

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12 December 2020

Decreased CD4+CD25+ T cells in peripheral blood of patients with systemic lupus erythematosus

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12 December 2020

Activation of epithelial and myoepithelial cells in the salivary glands of patients with Sjögren's syndrome: high expression of intercellular adhesion molecule-1 (ICAM.1) in biopsy specimens and cultured cells

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12 December 2020

Altered cytokine balance in the tear fluid and conjunctiva of patients with Sjögren's syndrome keratoconjunctivitis sicca

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12 December 2020

The transcription factor GATA-3 is necessary and sufficient for Th2 cytokine gene expression in CD4 T cells

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12 December 2020

Coordinate expansion of 'fetal type' lymphocytes (TCR gamma delta+T and CD5+B) in rheumatoid arthritis and primary Sjögren's syndrome

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12 December 2020

CD4(+)CD25(+) regulatory T cells in rheumatoid arthritis: differences in the presence, phenotype, and function between peripheral blood and synovial fluid

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12 December 2020

Immune responses in healthy and allergic individuals are characterized by a fine balance between allergen-specific T regulatory 1 and T helper 2 cells

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12 December 2020

The role of epithelial cells in the initiation and perpetuation of autoimmune lesions: lessons from Sjogren's syndrome (autoimmune epithelitis).

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12 December 2020

CD4+ CD25+ suppressor T cells: more questions than answers

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12 December 2020

Regulation of immunity by self-reactive T cells

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12 December 2020

Inhibition of submandibular and lacrimal gland infiltration in nonobese diabetic mice by transgenic expression of soluble TNF-receptor p55.

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12 December 2020

Regulatory T-cell therapy: is it ready for the clinic?

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12 December 2020

Expression of B7 costimulatory molecules by salivary gland epithelial cells in patients with Sjögren's syndrome

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12 December 2020

Increased circulating levels and salivary gland expression of interleukin-18 in patients with Sjögren's syndrome: relationship with autoantibody production and lymphoid organization of the periductal inflammatory infiltrate

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12 December 2020

An immunomodulatory role for CD4(+)CD25(+) regulatory T lymphocytes in hepatitis C virus infection.

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12 December 2020

CD4+CD25+ regulatory T-cell deficiency in patients with hepatitis C-mixed cryoglobulinemia vasculitis.

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12 December 2020

Interleukin-23 rather than interleukin-12 is the critical cytokine for autoimmune inflammation of the brain

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12 December 2020

Characterization of peripheral natural killer cells in primary Sjögren’s syndrome: Impaired NK cell activity and low NK cell number

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12 December 2020

Cellular basis of ectopic germinal center formation and autoantibody production in the target organ of patients with Sjögren's syndrome

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12 December 2020

Gene expression profiling of minor salivary glands clearly distinguishes primary Sjögren's syndrome patients from healthy control subjects.

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12 December 2020

Possible function of salivary gland epithelial cells as nonprofessional antigen-presenting cells in the development of Sjögren's syndrome

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12 December 2020

Increased serum levels of interleukin 10 in Sjögren's syndrome; correlation with increased IgG1

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12 December 2020

Immunological consequences of thalidomide treatment in Sjögren's syndrome

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12 December 2020

Apoptosis and Sjögren syndrome

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12 December 2020

Immunopathogenesis of primary Sjögren's syndrome: implications for disease management and therapy

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12 December 2020

Autoimmune Sjögren's-like lesions in salivary glands of TGF-beta1-deficient mice are inhibited by adhesion-blocking peptides.

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12 December 2020

Induction and mechanism of action of transforming growth factor-beta-secreting Th3 regulatory cells

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12 December 2020

NKT cells: facts, functions and fallacies.

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12 December 2020

IFNgamma sensitizes for apoptosis by upregulating caspase-8 expression through the Stat1 pathway.

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12 December 2020

The ups and downs of T cell costimulation

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12 December 2020

Loss of functional suppression by CD4+CD25+ regulatory T cells in patients with multiple sclerosis

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12 December 2020

Preferential localization of CD8+ alpha E beta 7+ T cells around acinar epithelial cells with apoptosis in patients with Sjögren's syndrome

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12 December 2020

Ocular immune privilege and CD1d-reactive natural killer T cells

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12 December 2020

A CD4+ T-cell subset inhibits antigen-specific T-cell responses and prevents colitis

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12 December 2020

Local cytokine expression in the progression toward B cell malignancy in Sjögren's syndrome.

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12 December 2020

Genomic absence of the gene encoding T cell receptor Vbeta7.2 is linked to the presence of autoantibodies in Sjögren's syndrome

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12 December 2020

CD1d and natural T cells: how their properties jump-start the immune system

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12 December 2020

Dysfunction of T cell receptor AV24AJ18+, BV11+ double-negative regulatory natural killer T cells in autoimmune diseases

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12 December 2020

Association of transforming growth factor beta1 and tumor necrosis factor alpha polymorphisms with anti-SSB/La antibody secretion in patients with primary Sjögren's syndrome

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12 December 2020

Regulatory T cell epitope recognized by T cells from labial salivary glands of patients with Sjögren's syndrome

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12 December 2020

Immunotherapy of autoimmune encephalomyelitis with redirected CD4+CD25+ T lymphocytes

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12 December 2020

CD25+ cell depletion hastens the onset of severe disease in collagen-induced arthritis.

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12 December 2020

Transforming growth factor-beta: a general review

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12 December 2020

A range of CD4 T cell tolerance: partial inactivation to organ-specific antigen allows nondestructive thyroiditis or insulitis.

1 reference

12 December 2020

10.1007/S12016-007-8011-8

Identifiers

DOI

1 reference

17 August 2017

1 reference