(Q37010636)

17 August 2017

Insight into the role of Mg in hammerhead ribozyme catalysis from X-ray crystallography and molecular dynamics simulation (English)

1 reference

17 August 2017

0 references

X-ray crystallography

0 references

5

Darrin M York

1 reference

17 August 2017

Carlos Silva López

2

0 references

author name string

Tai-Sung Lee

series ordinal

1

1 reference

17 August 2017

Monika Martick

series ordinal

3

1 reference

17 August 2017

William G Scott

series ordinal

4

1 reference

17 August 2017

language of work or name

1 reference

1 March 2007

1 reference

Journal of Chemical Theory and Computation

17 August 2017

1 reference

17 August 2017

3

1 reference

17 August 2017

2

1 reference

17 August 2017

325-327

1 reference

CHARMM force field parameters for simulation of reactive intermediates in native and thio-substituted ribozymes

17 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2600717

Extraordinary rates of transition metal ion-mediated ribozyme catalysis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2600717

Tertiary contacts distant from the active site prime a ribozyme for catalysis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2600717

The structure-function dilemma of the hammerhead ribozyme

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2600717

Importance in catalysis of a magnesium ion with very low affinity for a hammerhead ribozyme

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2600717

Engineered allosteric ribozymes as biosensor components

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2600717

Ribozyme structures and mechanisms

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2600717

Biophysical and biochemical investigations of RNA catalysis in the hammerhead ribozyme

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2600717

Capture and visualization of a catalytic RNA enzyme-product complex using crystal lattice trapping and X-ray holographic reconstruction

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2600717

Molecular dynamics study displays near in-line attack conformations in the hammerhead ribozyme self-cleavage reaction

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2600717

The structural basis of hammerhead ribozyme self-cleavage

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2600717

A two-metal ion mechanism operates in the hammerhead ribozyme-mediated cleavage of an RNA substrate

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2600717

Evidence for a hydroxide ion bridging two magnesium ions at the active site of the hammerhead ribozyme

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2600717

Capturing the structure of a catalytic RNA intermediate: the hammerhead ribozyme

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2600717

Rescue of abasic hammerhead ribozymes by exogenous addition of specific bases

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2600717

Three conserved guanosines approach the reaction site in native and minimal hammerhead ribozymes.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2600717

Two-metal-ion mechanism for hammerhead-ribozyme catalysis

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2600717

Model for general acid-base catalysis by the hammerhead ribozyme: pH-activity relationships of G8 and G12 variants at the putative active site

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2600717

Identification of the hammerhead ribozyme metal ion binding site responsible for rescue of the deleterious effect of a cleavage site phosphorothioate

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2600717

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2600717

Involvement of a specific metal ion in the transition of the hammerhead ribozyme to its catalytic conformation.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2600717

Fast Cleavage Kinetics of a Natural Hammerhead Ribozyme

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2600717

Structure and binding of Mg(II) ions and di-metal bridge complexes with biological phosphates and phosphoranes

4 December 2018

1 reference

12 December 2020

Monitoring post-translational modification of proteins with allosteric ribozymes

1 reference

12 December 2020

NMR-based reappraisal of the coordination of a metal ion at the pro-Rp oxygen of the A9/G10.1 site in a hammerhead ribozyme

1 reference

12 December 2020

Molecular dynamics investigations of hammerhead ribozyme RNA

1 reference

12 December 2020

Identifiers

DOI

10.1021/CT6003142

1 reference

17 August 2017

1 reference

17 August 2017

PubMed publication ID

19079784

1 reference