(Q37027396)

17 August 2017

1 reference

title

Glycan antagonists and inhibitors: a fount for drug discovery (English)

1 reference

17 August 2017

1 reference

3

Jeffrey D Esko

1 reference

17 August 2017

Jillian R Brown

1

1 reference

PubMed ID

18066955

17 August 2017

Brett E Crawford

series ordinal

2

1 reference

17 August 2017

1 November 2007

1 reference

Critical Reviews in Biochemistry and Molecular Biology

17 August 2017

1 reference

17 August 2017

42

1 reference

17 August 2017

6

1 reference

17 August 2017

481-515

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Purification and characterization of 1-O-acylceramide synthase, a novel phospholipase A2 with transacylase activity.

17 August 2017

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

Glycosphingolipid depletion in fabry disease lymphoblasts with potent inhibitors of glucosylceramide synthase

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

MUC1 as a target antigen for cancer immunotherapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

Hyaluronan and hyaluronan synthases: potential therapeutic targets in cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

Elevation of the post-translational modification of proteins by O-linked N-acetylglucosamine leads to deterioration of the glucose-stimulated insulin secretion in the pancreas of diabetic Goto-Kakizaki rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

From pattern recognition receptor to regulator of homeostasis: the double-faced macrophage mannose receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

Glucose mediates the translocation of NeuroD1 by O-linked glycosylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

Prolonged incubation in PUGNAc results in increased protein O-Linked glycosylation and insulin resistance in rat skeletal muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

Perlecan is essential for cartilage and cephalic development

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

Discovery of Carbohydrate Sulfotransferase Inhibitors from a Kinase-Directed Library We thank Sharon Long and Dave Keating for providing both the NodH sulfotransferase and APS Kinase during our preliminary experiments and Jack Kirsch for [...]

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

The microtubule-associated protein tau is extensively modified with O-linked N-acetylglucosamine

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

Glycosidase inhibitors: update and perspectives on practical use.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

Chlorate--a potent inhibitor of protein sulfation in intact cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

Dystroglycan: from biosynthesis to pathogenesis of human disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

Bimosiamose, an inhaled small-molecule pan-selectin antagonist, attenuates late asthmatic reactions following allergen challenge in mild asthmatics: a randomized, double-blind, placebo-controlled clinical cross-over-trial.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

Tumor attenuation by combined heparan sulfate and polyamine depletion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

Biological evaluation of a series of 2-acetamido-2-deoxy-D-glucose analogs towards cellular glycosaminoglycan and protein synthesis in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

Rapid discovery of potent sulfotransferase inhibitors by diversity-oriented reaction in microplates followed by in situ screening

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

Evolution of carbohydrate antigens--microbial forces shaping host glycomes?

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

The sensitivity of murine spermiogenesis to miglustat is a quantitative trait: a pharmacogenetic study

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

Heparin and cancer revisited: mechanistic connections involving platelets, P-selectin, carcinoma mucins, and tumor metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

Fibroblast growth factors and their inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

Multimeric glycotherapeutics: new paradigm

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

N-Acyl derivatives of glucosamine as acceptor substrates for galactosyltransferase from bone and cartilage cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

Mucin-type O-glycans in human colon and breast cancer: glycodynamics and functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

PIG-A mutations in paroxysmal nocturnal hemoglobinuria and in normal hematopoiesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

Expression patterns of alpha 2,3-sialyltransferases and alpha 1,3-fucosyltransferases determine the mode of sialyl Lewis X inhibition by disaccharide decoys.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

A disaccharide-based inhibitor of glycosylation attenuates metastatic tumor cell dissemination

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

Synthesis and biological evaluation of gem-diamine 1-N-iminosugars related to L-iduronic acid as inhibitors of heparan sulfate 2-O-sulfotransferase

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

High-throughput identification of fucosyltransferase inhibitors using carbohydrate microarrays

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

Chemo-enzymatic synthesis of fluorinated sugar nucleotide: useful mechanistic Probes for glycosyltransferases

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

A novel carbohydrate-based therapeutic GCS-100 overcomes bortezomib resistance and enhances dexamethasone-induced apoptosis in multiple myeloma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

Determination of the substrate specificities of N-acetyl-d-glucosaminyltransferase

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

Recent progress in the design of selectin inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

A functional role for complex gangliosides: motor deficits in GM2/GD2 synthase knockout mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

The design and evaluation of heparin-binding foldamers

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

Carbohydrate mimetics-based glycosyltransferase inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

Siglecs and their roles in the immune system

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

Role of O-linked beta-N-acetylglucosamine modification in the subcellular distribution of alpha4 phosphoprotein and Sp1 in rat lymphoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

The cell biology of glycosphingolipids.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

Ameliorating skin-homing receptors on malignant T cells with a fluorosugar analog of N-acetylglucosamine: P-selectin ligand is a more sensitive target than E-selectin ligand

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

Glycosylation-dependent inhibition of cutaneous lymphocyte-associated antigen expression: implications in modulating lymphocyte migration to skin

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

Prevention of leukocyte migration to inflamed skin with a novel fluorosugar modifier of cutaneous lymphocyte-associated antigen

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

An analog of myristic acid with selective toxicity for African trypanosomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

The fatty acids in unremodelled trypanosome glycosyl-phosphatidylinositols

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

GlcNAcstatin: a picomolar, selective O-GlcNAcase inhibitor that modulates intracellular O-glcNAcylation levels

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

A new anticancer glycolipid monoclonal antibody, SC104, which directly induces tumor cell apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

Targeting glycosylation as a therapeutic approach

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

Inhibitors of the biosynthesis and processing of N-linked oligosaccharide chains

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

Core 2 oligosaccharide biosynthesis distinguishes between selectin ligands essential for leukocyte homing and inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

Sialyltransferase ST3Gal-IV operates as a dominant modifier of hemostasis by concealing asialoglycoprotein receptor ligands

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

Guanidinylated neomycin delivers large, bioactive cargo into cells through a heparan sulfate-dependent pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

Molecular diversity of heparan sulfate

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

A novel method to co-localize glycosaminoglycan-core oligosaccharide glycosyltransferases in rat liver Golgi. Co-localization of galactosyltransferase I with a sialyltransferase

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

Use of galactosyltransferase to assess the biological function of O-linked N-acetyl-d-glucosamine: a potential role for O-GlcNAc during cell division

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

Overcoming inhibition in the damaged spinal cord

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

The GPI biosynthetic pathway as a therapeutic target for African sleeping sickness.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

Glycosylphosphatidylinositol biosynthesis validated as a drug target for African sleeping sickness

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

Gangliosides as therapeutic targets for cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

Pathway for polyarginine entry into mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

Roles of mucin-type O-glycans in cell adhesion

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

MINI REVIEW Keratan sulfate: structure, biosynthesis, and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

Keratan sulfate biosynthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

Genetic alteration of endothelial heparan sulfate selectively inhibits tumor angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

The sugar code: functional lectinomics

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

Dynamic O-glycosylation of nuclear and cytosolic proteins: cloning and characterization of a neutral, cytosolic beta-N-acetylglucosaminidase from human brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

Immunization of metastatic breast cancer patients with a fully synthetic globo H conjugate: a phase I trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

Immunization of high-risk breast cancer patients with clustered sTn-KLH conjugate plus the immunologic adjuvant QS-21.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

Suppression of tumor growth and metastasis in Mgat5-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

Discovery of O-GlcNAc transferase inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

Cellular and humoral immune response to N-Glycolyl-GM3 elicited by prolonged immunotherapy with an anti-idiotypic vaccine in high-risk and metastatic breast cancer patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

Modulation of O-linked N-acetylglucosamine levels on nuclear and cytoplasmic proteins in vivo using the peptide O-GlcNAc-beta-N-acetylglucosaminidase inhibitor O-(2-acetamido-2-deoxy-D-glucopyranosylidene)amino-N-phenylcarbamate

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

Role of glycosylation in development

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

Small molecule inhibitors of mucin-type O-linked glycosylation from a uridine-based library

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

O-glycosylation of the mucin type

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

Overexpression of glutamine:fructose-6-phosphate amidotransferase in transgenic mice leads to insulin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

High interstitial fluid pressure - an obstacle in cancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

Systematic syntheses and inhibitory activities of bisubstrate-type inhibitors of sialyltransferases

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

Metastatic potential of colon carcinoma. Expression of ABO/Lewis-related antigens

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

Vaccination with Theratope (STn-KLH) as treatment for breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

The alpha(1,3)fucosyltransferases FucT-IV and FucT-VII exert collaborative control over selectin-dependent leukocyte recruitment and lymphocyte homing

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

Therapeutic potential of a novel synthetic selectin blocker, OJ-R9188, in allergic dermatitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

Mammalian Brain Morphogenesis and Midline Axon Guidance Require Heparan Sulfate

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

Robust immune responses elicited by a fully synthetic three-component vaccine

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

A novel endoglycoceramidase hydrolyzes oligogalactosylceramides to produce galactooligosaccharides and ceramides.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

Mammalian hyaluronan synthases

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

Kinetics of endoglycoceramidase action toward cell-surface glycosphingolipids of erythrocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

Identification and cloning of a novel family of coiled-coil domain proteins that interact with O-GlcNAc transferase

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

Roles of the Tetratricopeptide Repeat Domain in O-GlcNAc Transferase Targeting and Protein Substrate Specificity

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

Synthesis of bisubstrate and donor analogues of sialyltransferase and their inhibitory activities

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

Synthesis of bisubstrate analogues targeting alpha-1,3-fucosyltransferase and their activities

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

Delayed symptom onset and increased life expectancy in Sandhoff disease mice treated with N-butyldeoxynojirimycin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

Methyl-3-O-(2-acetamido-2-deoxy-6-thio-beta-D-glucopyranosyl)-beta- D-galactopyranoside: a slow reacting acceptor-analogue which inhibits glycosylation by UDP-D-galactose-N-acetyl-D-glucosamine-(1----4)-beta-D-galactosyltra nsf erase

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

Characterization of inhibitory activities and binding mode of synthetic 6'-modified methyl N-acetyl-beta-lactosaminide toward rat liver CMP-D-Neu5Ac: D-galactoside-(2-->6)-alpha-D-sialyltransferase

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

Specific and flexible roles of heparan sulfate modifications in Drosophila FGF signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

Semaphorin 5A is a bifunctional axon guidance cue regulated by heparan and chondroitin sulfate proteoglycans

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

Tyrosylprotein sulfotransferase inhibitors generated by combinatorial target-guided ligand assembly

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

An evolving view of the eukaryotic oligosaccharyltransferase

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

Modulation of cell surface heparan sulfate structure by growth of cells in the presence of chlorate

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

Modulating leukocyte recruitment in inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

Animal lectins: a historical introduction and overview

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

P-selectin deficiency attenuates tumor growth and metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

Distinct selectin ligands on colon carcinoma mucins can mediate pathological interactions among platelets, leukocytes, and endothelium

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

Structural determination of five novel tetrasaccharides containing 3-O-sulfated D-glucuronic acid and two rare oligosaccharides containing a beta-D-glucose branch isolated from squid cartilage chondroitin sulfate E.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

The cell-surface heparan sulfate proteoglycan glypican-1 regulates growth factor action in pancreatic carcinoma cells and is overexpressed in human pancreatic cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

Inhibition of selectin-dependent tumor cell adhesion to endothelial cells and platelets by blocking O-glycosylation of these cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

Combinatorial ganglioside biosynthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

Alloxan is an inhibitor of the enzyme O-linked N-acetylglucosamine transferase

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

Dynamic glycosylation of nuclear and cytosolic proteins. Cloning and characterization of a unique O-GlcNAc transferase with multiple tetratricopeptide repeats

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

Interactions between heparan sulfate and proteins: the concept of specificity

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

Vaccination of patients with small-cell lung cancer with synthetic fucosyl GM-1 conjugated to keyhole limpet hemocyanin

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

Vaccination of small cell lung cancer patients with polysialic acid or N-propionylated polysialic acid conjugated to keyhole limpet hemocyanin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

Intracellular inhibition of blood group A glycosyltransferase

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

Loss of HSulf-1 up-regulates heparin-binding growth factor signaling in cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

Biology of gangliosides: neuritogenic and neuronotrophic properties

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

Improved Inhibitors of Glucosylceramide Synthase

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

Structure of acid beta-glucosidase with pharmacological chaperone provides insight into Gaucher disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

Disruption of gastrulation and heparan sulfate biosynthesis in EXT1-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

Examination of the substrate specificity of heparin and heparan sulfate lyases

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

CS lyases: structure, activity, and applications in analysis and the treatment of diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

O-GlcNAcylation regulates phosphorylation of tau: a mechanism involved in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

A genetic approach to Mammalian glycan function

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

Roles of O-fucose glycans in notch signaling revealed by mutant mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

Liver heparan sulfate proteoglycans mediate clearance of triglyceride-rich lipoproteins independently of LDL receptor family members

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

O-GlcNAcase uses substrate-assisted catalysis: kinetic analysis and development of highly selective mechanism-inspired inhibitors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

Characterization of glycoproteins and their associated oligosaccharides through the use of endoglycosidases

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

1,10-Phenanthroline inhibits glycosylphosphatidylinositol anchoring by preventing phosphoethanolamine addition to glycosylphosphatidylinositol anchor precursors

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

ABH and Lewis histo-blood group antigens, a model for the meaning of oligosaccharide diversity in the face of a changing world

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

Synthesis and evaluation of transition-state analogue inhibitors of alpha-1,3-fucosyltransferase

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

Aglycone structure influences alpha-fucosyltransferase III activity using N-acetyllactosamine glycoside acceptors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

Synthesis of N-acetyllactosamine derivatives with variation in the aglycon moiety for the study of inhibition of sialyl Lewis x expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

Binding sites and endocytosis of heparin and polylysine are changed when the two molecules are given as a complex to chinese hamster ovary cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

N-linked glycan recognition and processing: the molecular basis of endoplasmic reticulum quality control

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

Mechanism and specificity of human alpha-1,3-fucosyltransferase V.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

Involvement of carbohydrate antigen sialyl Lewis(x) in colorectal cancer metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

A novel oligosaccharide, GlcA beta 1-4Xyl beta 1-(4-methylumbelliferone), synthesized by human cultured skin fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

Hydrophobic glycosides of N-acetylglucosamine can act as primers for polylactosamine synthesis and can affect glycolipid synthesis in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

Mechanisms of heparin induced anti-cancer activity in experimental cancer models

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

Inhibition kinetics of carba- and C-fucosyl analogues of GDP-fucose against fucosyltransferase V: implication for the reaction mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

Ogt-dependent X-chromosome-linked protein glycosylation is a requisite modification in somatic cell function and embryo viability

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

Thematic review series: lipid posttranslational modifications. GPI anchoring of protein in yeast and mammalian cells, or: how we learned to stop worrying and love glycophospholipids.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

Prevention of lysosomal storage in Tay-Sachs mice treated with N-butyldeoxynojirimycin

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

Protamine sulphate, heparin, and blood coagulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

N -butyldeoxynojirimycin reduces growth and ganglioside content of experimental mouse brain tumours

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

Defective heparan sulfate biosynthesis and neonatal lethality in mice lacking N-deacetylase/N-sulfotransferase-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

Inhibition of glycosaminoglycan synthesis using rhodamine B in a mouse model of mucopolysaccharidosis type IIIA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

VEGF165-binding sites within heparan sulfate encompass two highly sulfated domains and can be liberated by K5 lyase

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

Reduction of O-GlcNAc protein modification does not prevent insulin resistance in 3T3-L1 adipocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

Ligands for L-selectin: homing, inflammation, and beyond

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

Pilot study of a heptavalent vaccine-keyhole limpet hemocyanin conjugate plus QS21 in patients with epithelial ovarian, fallopian tube, or peritoneal cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

Selective effects of sodium chlorate treatment on the sulfation of heparan sulfate

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

Identification of a novel glycosaminoglycan core-like molecule. II. Alpha-GalNAc-capped xylosides can be made by many cell types

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

Disaccharide uptake and priming in animal cells: inhibition of sialyl Lewis X by acetylated Gal beta 1-->4GlcNAc beta-O-naphthalenemethanol

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

Fucosylation of disaccharide precursors of sialyl LewisX inhibit selectin-mediated cell adhesion

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

Synthesis and glycan priming activity of acetylated disaccharides.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

Novel concatameric heparin-binding peptides reverse heparin and low-molecular-weight heparin anticoagulant activities in patient plasma in vitro and in rats in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

Lectin control of protein folding and sorting in the secretory pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

Stimulation of synthesis of free chondroitin sulfate chains by beta-D-xylosides in cultured cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

Efficient sialyltransferase inhibitors based on glycosides of N-acetylglucosamine

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

Differential effect of 1,10-phenanthroline on mammalian, yeast, and parasite glycosylphosphatidylinositol anchor synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

The O-GlcNAc transferase gene resides on the X chromosome and is essential for embryonic stem cell viability and mouse ontogeny

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

O-glycosylation of EGF repeats: identification and initial characterization of a UDP-glucose: protein O-glucosyltransferase

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

Antisense targeting of perlecan blocks tumor growth and angiogenesis in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

Differences between the trypanosomal and human GlcNAc-PI de-N-acetylases of glycosylphosphatidylinositol membrane anchor biosynthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

Carbohydrates as future anti-adhesion drugs for infectious diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

Mice lacking complex gangliosides develop Wallerian degeneration and myelination defects

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

Anti-metastatic effect of the sialyl Lewis-X analog GSC-150 on the human colon carcinoma derived cell line KM12-HX in the mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

Parasite and mammalian GPI biosynthetic pathways can be distinguished using synthetic substrate analogues

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

Selective inhibitors of the glycosylphosphatidylinositol biosynthetic pathway of Trypanosoma brucei.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

Specificity of GlcNAc-PI de-N-acetylase of GPI biosynthesis and synthesis of parasite-specific suicide substrate inhibitors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

Substrate specificity of the Plasmodium falciparum glycosylphosphatidylinositol biosynthetic pathway and inhibition by species-specific suicide substrates

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

Chemical validation of GPI biosynthesis as a drug target against African sleeping sickness

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

Differential requirements for the O-linked branching enzyme core 2 beta1-6-N-glucosaminyltransferase in biosynthesis of ligands for E-selectin and P-selectin

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

Uncoupling of chondroitin sulfate glycosaminoglycan synthesis by brefeldin A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

Selective action of the iminosugar isofagomine, a pharmacological chaperone for mutant forms of acid-beta-glucosidase

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

Hyaluronan fragments: an information-rich system

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

Mice deficient in Ext2 lack heparan sulfate and develop exostoses

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

Aspects of the biology of hyaluronan, a largely neglected but extremely versatile molecule

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

Alkylated imino sugars, reversible male infertility-inducing agents, do not affect the genetic integrity of male mouse germ cells during short-term treatment despite induction of sperm deformities

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

Identification of a species-specific inhibitor of glycosylphosphatidylinositol synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

Mice with disrupted GM2/GD2 synthase gene lack complex gangliosides but exhibit only subtle defects in their nervous system

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

Selective inhibition of beta-1,4- and alpha-1,3-galactosyltransferases: donor sugar-nucleotide based approach

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

Enzymatic deglycosylation of asparagine-linked glycans: purification, properties, and specificity of oligosaccharide-cleaving enzymes from Flavobacterium meningosepticum

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

All in the family: the UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferases

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

An inhibitor of O-glycosylation induces apoptosis in NIH3T3 cells and developing mouse embryonic mandibular tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

Stemming the tide: glycosphingolipid synthesis inhibitors as therapy for storage diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

Soluble 3-O-sulfated heparan sulfate can trigger herpes simplex virus type 1 entry into resistant Chinese hamster ovary (CHO-K1) cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

Hyaluronan-cell interactions in cancer and vascular disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

Hyaluronan: from extracellular glue to pericellular cue.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

Functional analysis of the chondroitin 6-sulfotransferase gene in relation to lymphocyte subpopulations, brain development, and oversulfated chondroitin sulfates

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

A novel class of potent nonglycosidic and nonpeptidic pan-selectin inhibitors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

Identification of novel inhibitors of UDP-Glc 4'-epimerase, a validated drug target for african sleeping sickness.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

Concepts and principles of O-linked glycosylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

Selectin ligands: will the real ones please stand up?

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

Siglecs--the major subfamily of I-type lectins

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

A 96-well dot-blot assay for carbohydrate sulfotransferases

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

Therapeutic applications of glycosaminoglycans

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

Elevated nucleocytoplasmic glycosylation by O-GlcNAc results in insulin resistance associated with defects in Akt activation in 3T3-L1 adipocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

Selectin-mucin interactions as a probable molecular explanation for the association of Trousseau syndrome with mucinous adenocarcinomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

Systematic Analysis of proteoglycan modification sites in Caenorhabditis elegans by scanning mutagenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

Interaction of heparin with two synthetic peptides that neutralize the anticoagulant activity of heparin

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

Heparin's anti-inflammatory effects require glucosamine 6-O-sulfation and are mediated by blockade of L- and P-selectins

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

Chondrodysplasia of gene knockout mice for aggrecan and link protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

Glycans as endocytosis signals: the cases of the asialoglycoprotein and hyaluronan/chondroitin sulfate receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

Synthesis of deoxy and acylamino derivatives of lactose and use of these for probing the active site of Neisseria meningitidis N-acetylglucosaminyltransferase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

Disrupting the enzyme complex regulating O-GlcNAcylation blocks signaling and development

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

Analysis of PUGNAc and NAG-thiazoline as transition state analogues for human O-GlcNAcase: mechanistic and structural insights into inhibitor selectivity and transition state poise

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

An inhibitor of the human UDP-GlcNAc 4-epimerase identified from a uridine-based library: a strategy to inhibit O-linked glycosylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

Inhibition of human HT-29 colon carcinoma cell adhesion by a 4-fluoro-glucosamine analogue

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

Defective angiogenesis and fatal embryonic hemorrhage in mice lacking core 1-derived O-glycans

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

A vital role for glycosphingolipid synthesis during development and differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

Enhanced insulin sensitivity in mice lacking ganglioside GM3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

Recruitment of O-GlcNAc transferase to promoters by corepressor mSin3A: coupling protein O-GlcNAcylation to transcriptional repression

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

Therapeutic value of glycosaminoglycans in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

Phase I trial of a human-mouse chimeric anti-disialoganglioside monoclonal antibody ch14.18 in patients with refractory neuroblastoma and osteosarcoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

Isofagomine- and 2,5-anhydro-2,5-imino-D-glucitol-based glucocerebrosidase pharmacological chaperones for Gaucher disease intervention.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

Cell signaling, the essential role of O-GlcNAc!

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

Repetitive Ser-Gly sequences enhance heparan sulfate assembly in proteoglycans

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

Structural studies of the binding of the anti-ulcer drug sucrose octasulfate to acidic fibroblast growth factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

Stable transfection of a glypican-1 antisense construct decreases tumorigenicity in PANC-1 pancreatic carcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

Synthesis of some second-generation substrate analogues of early intermediates in the biosynthetic pathway of glycosylphosphatidylinositol membrane anchors

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

Stereoselective synthesis of phosphoramidate α(2-6)Sialyltransferase transition-State analogue inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10409230701751611

10.1080/10409230701751611

21 January 2018

Identifiers

DOI

1 reference

17 August 2017

1 reference

PubMed ID

18066955