(Q37032338)

17 August 2017

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title

Simplified apoptotic cascades (English)

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17 August 2017

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Mehregan Movassagh

1

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17 August 2017

Roger S-Y Foo

series ordinal

2

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17 August 2017

publication date

1 June 2008

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17 August 2017

published in

Heart Failure Reviews

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17 August 2017

volume

13

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17 August 2017

issue

2

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17 August 2017

page(s)

111-119

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https://scigraph.springernature.com/pub.10.1007/s10741-007-9070-x

17 August 2017

exact match

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cites work

Soluble Fas Apo-1 splicing variants and apoptosis

1 reference

https://api.crossref.org/works/10.1007%2FS10741-007-9070-X

Fas receptor signaling inhibits glycogen synthase kinase 3 beta and induces cardiac hypertrophy following pressure overload

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10741-007-9070-X

Involvement of CD95/Apo1/Fas in Cell Death After Myocardial Ischemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10741-007-9070-X

A mechanistic role for cardiac myocyte apoptosis in heart failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10741-007-9070-X

Norepinephrine stimulates apoptosis in adult rat ventricular myocytes by activation of the beta-adrenergic pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10741-007-9070-X

Identification of DIABLO, a mammalian protein that promotes apoptosis by binding to and antagonizing IAP proteins

21 January 2018

1 reference

12 December 2020

Programmed cell death in Caenorhabditis elegans

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12 December 2020

Cross-talk between two cysteine protease families. Activation of caspase-12 by calpain in apoptosis

1 reference

12 December 2020

Activation of caspase-12, an endoplastic reticulum (ER) resident caspase, through tumor necrosis factor receptor-associated factor 2-dependent mechanism in response to the ER stress

1 reference

12 December 2020

Bid, Bax, and lipids cooperate to form supramolecular openings in the outer mitochondrial membrane

1 reference

12 December 2020

Blocking the development of postischemic cardiomyopathy with viral gene transfer of the apoptosis repressor with caspase recruitment domain

1 reference

12 December 2020

Apoptosis in heart failure represents programmed cell survival, not death, of cardiomyocytes and likelihood of reverse remodeling

1 reference

12 December 2020

Differential modulation of endotoxin responsiveness by human caspase-12 polymorphisms

1 reference

12 December 2020

Apoptosis: the germs of death

1 reference

12 December 2020

Prolonged endoplasmic reticulum stress in hypertrophic and failing heart after aortic constriction: possible contribution of endoplasmic reticulum stress to cardiac myocyte apoptosis

1 reference

12 December 2020

Enhanced Galphaq signaling: a common pathway mediates cardiac hypertrophy and apoptotic heart failure

1 reference

12 December 2020

Caspase-2 acts upstream of mitochondria to promote cytochrome c release during etoposide-induced apoptosis

1 reference

12 December 2020

Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-beta

1 reference

12 December 2020

Conversion of Bcl-2 from protector to killer by interaction with nuclear orphan receptor Nur77/TR3

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12 December 2020

Cleavage of focal adhesion kinase by caspases during apoptosis

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12 December 2020

Conversion of Bcl-2 to a Bax-like death effector by caspases

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12 December 2020

Distinct BH3 domains either sensitize or activate mitochondrial apoptosis, serving as prototype cancer therapeutics

1 reference

12 December 2020

DNA damaging agents induce expression of Fas ligand and subsequent apoptosis in T lymphocytes via the activation of NF-kappa B and AP-1.

1 reference

12 December 2020

The PIDDosome, a protein complex implicated in activation of caspase-2 in response to genotoxic stress

1 reference

12 December 2020

PUMA, a novel proapoptotic gene, is induced by p53

1 reference

12 December 2020

Proapoptotic BAX and BAK modulate the unfolded protein response by a direct interaction with IRE1alpha

1 reference

12 December 2020

Caspases: enemies within

1 reference

12 December 2020

beta-adrenergic stimulation causes cardiocyte apoptosis: influence of tachycardia and hypertrophy

1 reference

12 December 2020

Fas/Apo-1 (CD95) receptor lacking the intracytoplasmic signaling domain protects tumor cells from Fas-mediated apoptosis.

1 reference

12 December 2020

Fas pathway is a critical mediator of cardiac myocyte death and MI during ischemia-reperfusion in vivo

1 reference

12 December 2020

Fas triggers an alternative, caspase-8-independent cell death pathway using the kinase RIP as effector molecule

1 reference

12 December 2020

Stretch-induced programmed myocyte cell death

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12 December 2020

The pathophysiology of mitochondrial cell death

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12 December 2020

p53 activates the CD95 (APO-1/Fas) gene in response to DNA damage by anticancer drugs

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12 December 2020

Mitochondrial p53 activates Bak and causes disruption of a Bak-Mcl1 complex.

1 reference

12 December 2020

Proapoptotic BAX and BAK: a requisite gateway to mitochondrial dysfunction and death

1 reference

12 December 2020

Bax-induced caspase activation and apoptosis via cytochrome c release from mitochondria is inhibitable by Bcl-xL.

1 reference

12 December 2020

Apoptosis repressor with caspase recruitment domain is required for cardioprotection in response to biomechanical and ischemic stress

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12 December 2020

Cell death: critical control points

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12 December 2020

Caspase activation: revisiting the induced proximity model

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12 December 2020

A serine protease, HtrA2, is released from the mitochondria and interacts with XIAP, inducing cell death

1 reference

12 December 2020

Human and mouse Fas (APO-1/CD95) death receptor genes each contain a p53-responsive element that is activated by p53 mutants unable to induce apoptosis

1 reference

12 December 2020

Mitochondrial death protein Nix is induced in cardiac hypertrophy and triggers apoptotic cardiomyopathy

1 reference

12 December 2020

Caspase-3-generated fragment of gelsolin: effector of morphological change in apoptosis

1 reference

12 December 2020

Telomere attrition and Chk2 activation in human heart failure

1 reference

12 December 2020

Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade

1 reference

12 December 2020

Functional consequences of caspase activation in cardiac myocytes

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12 December 2020

Cleavage of lamin A by Mch2 alpha but not CPP32: multiple interleukin 1 beta-converting enzyme-related proteases with distinct substrate recognition properties are active in apoptosis

1 reference

12 December 2020

PUMA couples the nuclear and cytoplasmic proapoptotic function of p53

1 reference

12 December 2020

Direct activation of Bax by p53 mediates mitochondrial membrane permeabilization and apoptosis

1 reference

12 December 2020

Cardiomyocyte apoptosis and progression of heart failure to transplantation

1 reference

12 December 2020

Inflammatory mediators in heart failure: homogeneity through heterogeneity

1 reference

12 December 2020

Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis

1 reference

12 December 2020

Ku70 suppresses the apoptotic translocation of Bax to mitochondria.

1 reference

12 December 2020

p53 has a direct apoptogenic role at the mitochondria

1 reference

12 December 2020

ASK1 is essential for endoplasmic reticulum stress-induced neuronal cell death triggered by expanded polyglutamine repeats

1 reference

12 December 2020

PUMA mediates the apoptotic response to p53 in colorectal cancer cells

1 reference

12 December 2020

The apoptosome activates caspase-9 by dimerization

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12 December 2020

Transgenic Galphaq overexpression induces cardiac contractile failure in mice

1 reference

12 December 2020

Apoptosis in heart failure: release of cytochrome c from mitochondria and activation of caspase-3 in human cardiomyopathy

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12 December 2020

Dimerization and release of molecular chaperone inhibition facilitate activation of eukaryotic initiation factor-2 kinase in response to endoplasmic reticulum stress

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12 December 2020

An induced proximity model for caspase-8 activation.

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12 December 2020

DFF, a heterodimeric protein that functions downstream of caspase-3 to trigger DNA fragmentation during apoptosis

1 reference

12 December 2020

Involvement of histone H1.2 in apoptosis induced by DNA double-strand breaks

1 reference

12 December 2020

The CED-3/ICE-like protease Mch2 is activated during apoptosis and cleaves the death substrate lamin A

1 reference

12 December 2020

Translational control by the ER transmembrane kinase/ribonuclease IRE1 under ER stress

1 reference

12 December 2020

Cytotoxicity-dependent APO-1 (Fas/CD95)-associated proteins form a death-inducing signaling complex (DISC) with the receptor

1 reference

12 December 2020

Death in Embryonic Systems

1 reference

12 December 2020

Proapoptotic BAX and BAK regulate the type 1 inositol trisphosphate receptor and calcium leak from the endoplasmic reticulum

1 reference

12 December 2020

Caspase-2 deficiency prevents programmed germ cell death resulting from cytokine insufficiency but not meiotic defects caused by loss of ataxia telangiectasia-mutated (Atm) gene function

1 reference

12 December 2020

Inhibition of cardiac myocyte apoptosis improves cardiac function and abolishes mortality in the peripartum cardiomyopathy of Galpha(q) transgenic mice

1 reference

12 December 2020

Death begets failure in the heart

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12 December 2020

Genomic amplification of a decoy receptor for Fas ligand in lung and colon cancer

1 reference

12 December 2020

Direct demonstration of a specific interaction between cyclophilin-D and the adenine nucleotide translocase confirms their role in the mitochondrial permeability transition

1 reference

12 December 2020

Requirement for caspase-2 in stress-induced apoptosis before mitochondrial permeabilization

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12 December 2020

Autoproteolytic activation of pro-caspases by oligomerization

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12 December 2020

Coupling of stress in the ER to activation of JNK protein kinases by transmembrane protein kinase IRE1

1 reference

12 December 2020

Inhibition of fas death signals by FLIPs

1 reference

12 December 2020

Soluble Fas/Apo-1 splicing variants and apoptosis

1 reference

12 December 2020

Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition

1 reference

12 December 2020

A caspase-activated DNase that degrades DNA during apoptosis, and its inhibitor ICAD

1 reference

12 December 2020

Caenorhabditis elegans CED-9 protein is a bifunctional cell-death inhibitor

1 reference

12 December 2020

Myocyte death in the failing human heart is gender dependent

1 reference

12 December 2020

The Bcl2 family: regulators of the cellular life-or-death switch

1 reference

12 December 2020

Targeted deletion of apoptosis signal-regulating kinase 1 attenuates left ventricular remodeling

1 reference

12 December 2020

Caspase cleaved BID targets mitochondria and is required for cytochrome c release, while BCL-XL prevents this release but not tumor necrosis factor-R1/Fas death

1 reference

12 December 2020

Apoptosis in the failing human heart

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12 December 2020

Loss of cyclophilin D reveals a critical role for mitochondrial permeability transition in cell death

1 reference

12 December 2020

An endoplasmic reticulum stress-specific caspase cascade in apoptosis. Cytochrome c-independent activation of caspase-9 by caspase-12

1 reference

12 December 2020

Telomerase reverse transcriptase promotes cardiac muscle cell proliferation, hypertrophy, and survival

1 reference

12 December 2020

Life in the balance: how BH3-only proteins induce apoptosis.

1 reference

12 December 2020

Mitochondrial permeability: dual role for the ADP/ATP translocator?

1 reference

12 December 2020

Mechanisms of disease: apoptosis in heart failure--seeing hope in death

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12 December 2020

The coordinate release of cytochrome c during apoptosis is rapid, complete and kinetically invariant

1 reference

12 December 2020

Caspases 3 and 7: key mediators of mitochondrial events of apoptosis

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12 December 2020

Loss of a gp130 cardiac muscle cell survival pathway is a critical event in the onset of heart failure during biomechanical stress

1 reference

12 December 2020

Stress signaling from the lumen of the endoplasmic reticulum: coordination of gene transcriptional and translational controls

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12 December 2020

Protection from Fas-mediated apoptosis by a soluble form of the Fas molecule

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12 December 2020

Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors

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12 December 2020

X-linked IAP is a direct inhibitor of cell-death proteases

1 reference

12 December 2020

Apoptosis in ischemic and reperfused rat myocardium

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12 December 2020

The multifaceted role of Fas signaling in immune cell homeostasis and autoimmunity

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12 December 2020

Inhibition by cyclosporin A of a Ca2+-dependent pore in heart mitochondria activated by inorganic phosphate and oxidative stress

1 reference

12 December 2020

Viral gene transfer of the antiapoptotic factor Bcl-2 protects against chronic postischemic heart failure

1 reference

12 December 2020

Apoptosis driven by IP(3)-linked mitochondrial calcium signals

1 reference

12 December 2020

The E3 ubiquitin ligase itch couples JNK activation to TNFalpha-induced cell death by inducing c-FLIP(L) turnover

1 reference

12 December 2020

Shrinkage necrosis: a distinct mode of cellular death.

1 reference

12 December 2020

Direct evidence for increased hydroxyl radicals originating from superoxide in the failing myocardium

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12 December 2020

The versatility and universality of calcium signalling

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12 December 2020

Death receptors: signaling and modulation

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12 December 2020

Angiotensin II induces apoptosis of adult ventricular myocytes in vitro

1 reference

12 December 2020

10.1007/S10741-007-9070-X

Identifiers

DOI

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17 August 2017

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