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Viral drug resistance and fitness.
scientific article published on January 2008
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1 reference
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Europe PubMed Central
PubMed publication ID
18086415
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18086415%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 December 2019
review article
1 reference
stated in
Europe PubMed Central
title
Viral drug resistance and fitness
(English)
1 reference
stated in
Europe PubMed Central
PubMed publication ID
18086415
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18086415%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 December 2019
main subject
viral drug resistance
1 reference
based on heuristic
inferred from title
drug resistance
1 reference
based on heuristic
inferred from title
author
Jan Weber
series ordinal
4
1 reference
stated in
Europe PubMed Central
PubMed publication ID
18086415
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18086415%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 December 2019
author name string
Miguel E Quiñones-Mateu
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed publication ID
18086415
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18086415%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 December 2019
Dawn M Moore-Dudley
series ordinal
2
1 reference
stated in
Europe PubMed Central
PubMed publication ID
18086415
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18086415%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 December 2019
Oyebisi Jegede
series ordinal
3
1 reference
stated in
Europe PubMed Central
PubMed publication ID
18086415
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18086415%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 December 2019
Eric J Arts
series ordinal
5
1 reference
stated in
Europe PubMed Central
PubMed publication ID
18086415
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18086415%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 December 2019
language of work or name
English
1 reference
based on heuristic
inferred from title
publication date
1 January 2008
1 reference
stated in
Europe PubMed Central
PubMed publication ID
18086415
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18086415%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 December 2019
published in
Advances in Pharmacology
1 reference
stated in
Europe PubMed Central
PubMed publication ID
18086415
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18086415%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 December 2019
volume
56
1 reference
stated in
Europe PubMed Central
PubMed publication ID
18086415
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18086415%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 December 2019
page(s)
257-296
1 reference
stated in
Europe PubMed Central
PubMed publication ID
18086415
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18086415%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 December 2019
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Escape of HIV-1 from a small molecule CCR5 inhibitor is not associated with a fitness loss
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Cross-resistance among nonnucleoside reverse transcriptase inhibitors limits recycling efavirenz after nevirapine failure
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Mutants of human immunodeficiency virus type 1 (HIV-1) reverse transcriptase resistant to nonnucleoside reverse transcriptase inhibitors demonstrate altered rates of RNase H cleavage that correlate with HIV-1 replication fitness in cell culture
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Is HIV-1 evolving to a less virulent form in humans?
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Phenotypic mechanism of HIV-1 resistance to 3'-azido-3'-deoxythymidine (AZT): increased polymerization processivity and enhanced sensitivity to pyrophosphate of the mutant viral reverse transcriptase
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Isolation and characterization of human immunodeficiency virus type 1 resistant to the small-molecule CCR5 antagonist TAK-652.
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Human immunodeficiency virus type 1 mutations selected in patients failing efavirenz combination therapy
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Genotypic correlates of phenotypic resistance to efavirenz in virus isolates from patients failing nonnucleoside reverse transcriptase inhibitor therapy
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Reduced replication of 3TC-resistant HIV-1 variants in primary cells due to a processivity defect of the reverse transcriptase enzyme.
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Comparing the ex vivo fitness of CCR5-tropic human immunodeficiency virus type 1 isolates of subtypes B and C.
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Evolution of phenotypic drug susceptibility and viral replication capacity during long-term virologic failure of protease inhibitor therapy in human immunodeficiency virus-infected adults
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Higher CD4+ T cell counts associated with low viral pol replication capacity among treatment-naive adults in early HIV-1 infection
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Susceptibility of HIV type 1 to the fusion inhibitor T-20 is reduced on insertion of host intercellular adhesion molecule 1 in the virus membrane
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Kinetics of HIV-1 RNA and resistance-associated mutations after cessation of antiretroviral combination therapy
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Resistance of human immunodeficiency virus type 1 to protease inhibitors: selection of resistance mutations in the presence and absence of the drug.
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Ordered appearance of zidovudine resistance mutations during treatment of 18 human immunodeficiency virus-positive subjects
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Selective excision of AZTMP by drug-resistant human immunodeficiency virus reverse transcriptase
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A V106M mutation in HIV-1 clade C viruses exposed to efavirenz confers cross-resistance to non-nucleoside reverse transcriptase inhibitors
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Reduced susceptibility of human immunodeficiency virus type 1 (HIV-1) from patients with primary HIV infection to nonnucleoside reverse transcriptase inhibitors is associated with variation at novel amino acid sites
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Core structure of gp41 from the HIV envelope glycoprotein
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Interaction of the CC-chemokine RANTES with glycosaminoglycans activates a p44/p42 mitogen-activated protein kinase-dependent signaling pathway and enhances human immunodeficiency virus type 1 infectivity
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7 January 2021
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HIV drug resistance and viral fitness.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2807%2956009-6
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7 January 2021
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inferred from DOI database lookup
In vivo emergence of HIV-1 variants resistant to multiple protease inhibitors
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7 January 2021
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Human immunodeficiency virus type 1 protease cleavage site mutations associated with protease inhibitor cross-resistance selected by indinavir, ritonavir, and/or saquinavir
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS1054-3589%2807%2956009-6
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7 January 2021
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Insertion of two amino acids combined with changes in reverse transcriptase containing tyrosine-215 of HIV-1 resistant to multiple nucleoside analogs
1 reference
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Crossref
reference URL
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7 January 2021
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Resistance to newly approved and investigational protease inhibitors.
1 reference
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Crossref
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based on heuristic
inferred from DOI database lookup
TMC114, a novel human immunodeficiency virus type 1 protease inhibitor active against protease inhibitor-resistant viruses, including a broad range of clinical isolates
1 reference
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Crossref
reference URL
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7 January 2021
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inferred from DOI database lookup
Host-parasite dynamics and outgrowth of virus containing a single K70R amino acid change in reverse transcriptase are responsible for the loss of human immunodeficiency virus type 1 RNA load suppression by zidovudine
1 reference
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Crossref
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7 January 2021
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Interruption of enfuvirtide in HIV-1 infected adults with incomplete viral suppression on an enfuvirtide-based regimen
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Delavirdine susceptibilities and associated reverse transcriptase mutations in human immunodeficiency virus type 1 isolates from patients in a phase I/II trial of delavirdine monotherapy (ACTG 260)
1 reference
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Crossref
reference URL
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7 January 2021
based on heuristic
inferred from DOI database lookup
Sensitivity of human immunodeficiency virus type 1 to the fusion inhibitor T-20 is modulated by coreceptor specificity defined by the V3 loop of gp120
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2807%2956009-6
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7 January 2021
based on heuristic
inferred from DOI database lookup
Sensitivity of human immunodeficiency virus type 1 to fusion inhibitors targeted to the gp41 first heptad repeat involves distinct regions of gp41 and is consistently modulated by gp120 interactions with the coreceptor
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2807%2956009-6
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7 January 2021
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inferred from DOI database lookup
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1 reference
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Crossref
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7 January 2021
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inferred from DOI database lookup
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1 reference
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7 January 2021
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1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2807%2956009-6
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7 January 2021
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inferred from DOI database lookup
Second locus involved in human immunodeficiency virus type 1 resistance to protease inhibitors
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2807%2956009-6
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7 January 2021
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inferred from DOI database lookup
Novel Gag-Pol frameshift site in human immunodeficiency virus type 1 variants resistant to protease inhibitors
1 reference
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Crossref
reference URL
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7 January 2021
based on heuristic
inferred from DOI database lookup
Selection and characterization of HIV-1 showing reduced susceptibility to the non-peptidic protease inhibitor tipranavir
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2807%2956009-6
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7 January 2021
based on heuristic
inferred from DOI database lookup
A mutation in reverse transcriptase of bis(heteroaryl)piperazine-resistant human immunodeficiency virus type 1 that confers increased sensitivity to other nonnucleoside inhibitors
1 reference
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Crossref
reference URL
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7 January 2021
based on heuristic
inferred from DOI database lookup
Impact of clinical reverse transcriptase sequences on the replication capacity of HIV-1 drug-resistant mutants
1 reference
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reference URL
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7 January 2021
based on heuristic
inferred from DOI database lookup
A drug resistance mutation in the inhibitor binding pocket of human immunodeficiency virus type 1 reverse transcriptase impairs DNA synthesis and RNA degradation
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2807%2956009-6
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7 January 2021
based on heuristic
inferred from DOI database lookup
Mechanistic studies examining the efficiency and fidelity of DNA synthesis by the 3TC-resistant mutant (184V) of HIV-1 reverse transcriptase
1 reference
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7 January 2021
based on heuristic
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Development of resistance against diketo derivatives of human immunodeficiency virus type 1 by progressive accumulation of integrase mutations
1 reference
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7 January 2021
based on heuristic
inferred from DOI database lookup
Multiple mutations in human immunodeficiency virus-1 integrase confer resistance to the clinical trial drug S-1360.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2807%2956009-6
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7 January 2021
based on heuristic
inferred from DOI database lookup
Sensitive drug-resistance assays reveal long-term persistence of HIV-1 variants with the K103N nevirapine (NVP) resistance mutation in some women and infants after the administration of single-dose NVP: HIVNET 012.
1 reference
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7 January 2021
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Single-dose safety and pharmacokinetics of brecanavir, a novel human immunodeficiency virus protease inhibitor
1 reference
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7 January 2021
based on heuristic
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Phosphorylation of 3'-azido-3'-deoxythymidine and selective interaction of the 5'-triphosphate with human immunodeficiency virus reverse transcriptase
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2807%2956009-6
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7 January 2021
based on heuristic
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Characterization of a subtype D human immunodeficiency virus type 1 isolate that was obtained from an untreated individual and that is highly resistant to nonnucleoside reverse transcriptase inhibitors
1 reference
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7 January 2021
based on heuristic
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A novel genetic pathway of human immunodeficiency virus type 1 resistance to stavudine mediated by the K65R mutation
1 reference
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7 January 2021
based on heuristic
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Three new structures of the core domain of HIV-1 integrase: an active site that binds magnesium
1 reference
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7 January 2021
based on heuristic
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Biochemical and genetic characterizations of a novel human immunodeficiency virus type 1 inhibitor that blocks gp120-CD4 interactions
1 reference
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7 January 2021
based on heuristic
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Significance of amino acid variation at human immunodeficiency virus type 1 reverse transcriptase residue 210 for zidovudine susceptibility
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7 January 2021
based on heuristic
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Relative replicative fitness of zidovudine-resistant human immunodeficiency virus type 1 isolates in vitro
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7 January 2021
based on heuristic
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Effects of (-)-2'-deoxy-3'-thiacytidine (3TC) 5'-triphosphate on human immunodeficiency virus reverse transcriptase and mammalian DNA polymerases alpha, beta, and gamma
1 reference
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7 January 2021
based on heuristic
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Inhibitors of strand transfer that prevent integration and inhibit HIV-1 replication in cells
1 reference
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https://api.crossref.org/works/10.1016%2FS1054-3589%2807%2956009-6
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7 January 2021
based on heuristic
inferred from DOI database lookup
A naphthyridine carboxamide provides evidence for discordant resistance between mechanistically identical inhibitors of HIV-1 integrase
1 reference
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7 January 2021
based on heuristic
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Integrase inhibitors and cellular immunity suppress retroviral replication in rhesus macaques
1 reference
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7 January 2021
based on heuristic
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Durable efficacy of tipranavir-ritonavir in combination with an optimised background regimen of antiretroviral drugs for treatment-experienced HIV-1-infected patients at 48 weeks in the Randomized Evaluation of Strategic Intervention in multi-drug r
1 reference
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7 January 2021
based on heuristic
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Characterization of human immunodeficiency virus type 1 variants with increased resistance to a C2-symmetric protease inhibitor
1 reference
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https://api.crossref.org/works/10.1016%2FS1054-3589%2807%2956009-6
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7 January 2021
based on heuristic
inferred from DOI database lookup
Structure of unliganded HIV-1 reverse transcriptase at 2.7 A resolution: implications of conformational changes for polymerization and inhibition mechanisms
1 reference
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https://api.crossref.org/works/10.1016%2FS1054-3589%2807%2956009-6
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7 January 2021
based on heuristic
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Fitness comparison of thymidine analog resistance pathways in human immunodeficiency virus type 1.
1 reference
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https://api.crossref.org/works/10.1016%2FS1054-3589%2807%2956009-6
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7 January 2021
based on heuristic
inferred from DOI database lookup
Structure of a V3-containing HIV-1 gp120 core
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2807%2956009-6
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7 January 2021
based on heuristic
inferred from DOI database lookup
Relative replication fitness of a high-level 3'-azido-3'-deoxythymidine-resistant variant of human immunodeficiency virus type 1 possessing an amino acid deletion at codon 67 and a novel substitution (Thr-->Gly) at codon 69.
1 reference
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7 January 2021
based on heuristic
inferred from DOI database lookup
Amino acid deletion at codon 67 and Thr-to-Gly change at codon 69 of human immunodeficiency virus type 1 reverse transcriptase confer novel drug resistance profiles
1 reference
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https://api.crossref.org/works/10.1016%2FS1054-3589%2807%2956009-6
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7 January 2021
based on heuristic
inferred from DOI database lookup
Impact of HIV type 1 protease, reverse transcriptase, cleavage site, and p6 mutations on the virological response to quadruple therapy with saquinavir, ritonavir, and two nucleoside analogs.
1 reference
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https://api.crossref.org/works/10.1016%2FS1054-3589%2807%2956009-6
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7 January 2021
based on heuristic
inferred from DOI database lookup
Genotypic and phenotypic characterization of HIV-1 isolated from patients receiving (--)-2',3'-dideoxy-3'-thiacytidine
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2807%2956009-6
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7 January 2021
based on heuristic
inferred from DOI database lookup
Fifth mutation in human immunodeficiency virus type 1 reverse transcriptase contributes to the development of high-level resistance to zidovudine
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2807%2956009-6
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7 January 2021
based on heuristic
inferred from DOI database lookup
Structural and thermodynamic basis for the binding of TMC114, a next-generation human immunodeficiency virus type 1 protease inhibitor
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2807%2956009-6
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7 January 2021
based on heuristic
inferred from DOI database lookup
Amino acid 36 in the human immunodeficiency virus type 1 gp41 ectodomain controls fusogenic activity: implications for the molecular mechanism of viral escape from a fusion inhibitor
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2807%2956009-6
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7 January 2021
based on heuristic
inferred from DOI database lookup
Novel bis-tetrahydrofuranylurethane-containing nonpeptidic protease inhibitor (PI) UIC-94017 (TMC114) with potent activity against multi-PI-resistant human immunodeficiency virus in vitro.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2807%2956009-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Crystal structure at 3.5 A resolution of HIV-1 reverse transcriptase complexed with an inhibitor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2807%2956009-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Extensive polymorphisms observed in HIV-1 clade B protease gene using high-density oligonucleotide arrays.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2807%2956009-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Genetic and phenotypic analyses of human immunodeficiency virus type 1 escape from a small-molecule CCR5 inhibitor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2807%2956009-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Baseline susceptibility of primary human immunodeficiency virus type 1 to entry inhibitors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2807%2956009-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Role of the envelope genetic context in the development of enfuvirtide resistance in human immunodeficiency virus type 1-infected patients
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2807%2956009-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
3'-Azido-3'-deoxythymidine resistance suppressed by a mutation conferring human immunodeficiency virus type 1 resistance to nonnucleoside reverse transcriptase inhibitors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2807%2956009-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Multiple mutations in HIV-1 reverse transcriptase confer high-level resistance to zidovudine (AZT)
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2807%2956009-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Potential mechanism for sustained antiretroviral efficacy of AZT-3TC combination therapy
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2807%2956009-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A family of insertion mutations between codons 67 and 70 of human immunodeficiency virus type 1 reverse transcriptase confer multinucleoside analog resistance.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2807%2956009-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A small molecule HIV-1 inhibitor that targets the HIV-1 envelope and inhibits CD4 receptor binding
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2807%2956009-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Natural variation in the V3 crown of human immunodeficiency virus type 1 affects replicative fitness and entry inhibitor sensitivity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2807%2956009-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Relative replicative fitness of human immunodeficiency virus type 1 mutants resistant to enfuvirtide (T-20).
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2807%2956009-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Localized changes in the gp120 envelope glycoprotein confer resistance to human immunodeficiency virus entry inhibitors BMS-806 and #155.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2807%2956009-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Altered drug sensitivity, fitness, and evolution of human immunodeficiency virus type 1 with pol gene mutations conferring multi-dideoxynucleoside resistance
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2807%2956009-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Resistance-associated loss of viral fitness in human immunodeficiency virus type 1: phenotypic analysis of protease and gag coevolution in protease inhibitor-treated patients
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2807%2956009-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Thymidine analogue reverse transcriptase inhibitors resistance mutations profiles and association to other nucleoside reverse transcriptase inhibitors resistance mutations observed in the context of virological failure
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2807%2956009-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Genotypic and phenotypic analyses of HIV-1 in antiretroviral-experienced patients treated with tenofovir DF.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2807%2956009-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mechanisms involved in stimulation of human immunodeficiency virus type 1 replication by aminooxypentane RANTES.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2807%2956009-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Generation and properties of a human immunodeficiency virus type 1 isolate resistant to the small molecule CCR5 inhibitor, SCH-417690 (SCH-D).
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2807%2956009-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Differences in the fitness of two diverse wild-type human immunodeficiency virus type 1 isolates are related to the efficiency of cell binding and entry
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2807%2956009-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Replicative fitness of protease inhibitor-resistant mutants of human immunodeficiency virus type 1.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2807%2956009-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Characterization of envelope glycoprotein gp41 genotype and phenotypic susceptibility to enfuvirtide at baseline and on treatment in the phase III clinical trials TORO-1 and TORO-2.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2807%2956009-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Effects of specific zidovudine resistance mutations and substrate structure on nucleotide-dependent primer unblocking by human immunodeficiency virus type 1 reverse transcriptase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2807%2956009-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inhibition of the in vitro infectivity and cytopathic effect of human T-lymphotrophic virus type III/lymphadenopathy-associated virus (HTLV-III/LAV) by 2',3'-dideoxynucleosides
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2807%2956009-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
3'-Azido-3'-deoxythymidine (BW A509U): an antiviral agent that inhibits the infectivity and cytopathic effect of human T-lymphotropic virus type III/lymphadenopathy-associated virus in vitro
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2807%2956009-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Ordered accumulation of mutations in HIV protease confers resistance to ritonavir
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2807%2956009-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
ATP-dependent removal of nucleoside reverse transcriptase inhibitors by human immunodeficiency virus type 1 reverse transcriptase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2807%2956009-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mutations conferring resistance to human immunodeficiency virus type 1 fusion inhibitors are restricted by gp41 and Rev-responsive element functions
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2807%2956009-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
T20-insensitive HIV-1 from naive patients exhibits high viral fitness in a novel dual-color competition assay on primary cells.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2807%2956009-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Stochastic processes strongly influence HIV-1 evolution during suboptimal protease-inhibitor therapy
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2807%2956009-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Increased fitness of drug resistant HIV-1 protease as a result of acquisition of compensatory mutations during suboptimal therapy
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2807%2956009-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Implications of antiretroviral resistance on viral fitness
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2807%2956009-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The K65R mutation in human immunodeficiency virus type 1 reverse transcriptase exhibits bidirectional phenotypic antagonism with thymidine analog mutations
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2807%2956009-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mutations in the protease gene of human immunodeficiency virus type 1 affect release and stability of virus particles
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2807%2956009-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A phase I/II study of 2'-deoxy-3'-thiacytidine (lamivudine) in patients with advanced human immunodeficiency virus infection
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2807%2956009-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Amprenavir-resistant HIV-1 exhibits lopinavir cross-resistance and reduced replication capacity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2807%2956009-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Relative replication fitness of multi-nucleoside analogue-resistant HIV-1 strains bearing a dipeptide insertion in the fingers subdomain of the reverse transcriptase and mutations at codons 67 and 215.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2807%2956009-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
HIV-1 clones resistant to a small molecule CCR5 inhibitor use the inhibitor-bound form of CCR5 for entry
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2807%2956009-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Endogenous reverse transcription assays reveal high-level resistance to the triphosphate of (-)2'-dideoxy-3'-thiacytidine by mutated M184V human immunodeficiency virus type 1
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2807%2956009-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Fitness of drug resistant HIV-1: methodology and clinical implications
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2807%2956009-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Virus fitness: concept, quantification, and application to HIV population dynamics.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2807%2956009-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Characterization of the reverse transcriptase of a human immunodeficiency virus type 1 group O isolate.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2807%2956009-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A dual infection/competition assay shows a correlation between ex vivo human immunodeficiency virus type 1 fitness and disease progression
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2807%2956009-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Insertions in the reverse transcriptase increase both drug resistance and viral fitness in a human immunodeficiency virus type 1 isolate harboring the multi-nucleoside reverse transcriptase inhibitor resistance 69 insertion complex mutation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2807%2956009-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Role of the human immunodeficiency virus type 1 envelope gene in viral fitness.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2807%2956009-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Sensitivity of HIV-1 to entry inhibitors correlates with envelope/coreceptor affinity, receptor density, and fusion kinetics
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2807%2956009-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Enfuvirtide resistance mutations: impact on human immunodeficiency virus envelope function, entry inhibitor sensitivity, and virus neutralization
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2807%2956009-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
HIV chemotherapy
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2807%2956009-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Human immunodeficiency virus type 1 mutants resistant to nonnucleoside inhibitors of reverse transcriptase arise in tissue culture
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2807%2956009-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Determinants of human immunodeficiency virus type 1 resistance to gp41-derived inhibitory peptides.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2807%2956009-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The structure of unliganded reverse transcriptase from the human immunodeficiency virus type 1
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2807%2956009-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Human immunodeficiency virus type 1 viral background plays a major role in development of resistance to protease inhibitors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2807%2956009-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Characterization of human immunodeficiency viruses resistant to oxathiolane-cytosine nucleosides
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2807%2956009-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Multiple drug resistance to nucleoside analogues and nonnucleoside reverse transcriptase inhibitors in an efficiently replicating human immunodeficiency virus type 1 patient strain
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2807%2956009-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Combination therapy with zidovudine and didanosine selects for drug-resistant human immunodeficiency virus type 1 strains with unique patterns of pol gene mutations.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2807%2956009-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Antiretroviral compounds: mechanisms underlying failure of HAART to eradicate HIV-1.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2807%2956009-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Emergence of human immunodeficiency virus type 1 variants with resistance to multiple dideoxynucleosides in patients receiving therapy with dideoxynucleosides.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2807%2956009-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Conformational changes in HIV-1 reverse transcriptase induced by nonnucleoside reverse transcriptase inhibitor binding
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2807%2956009-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Structure of the binding site for nonnucleoside inhibitors of the reverse transcriptase of human immunodeficiency virus type 1
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2807%2956009-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mechanism of inhibition of HIV-1 reverse transcriptase by nonnucleoside inhibitors.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2807%2956009-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Impact of clade diversity on HIV-1 virulence, antiretroviral drug sensitivity and drug resistance
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2807%2956009-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
3'-Azido-3'-deoxythymidine triphosphate as an inhibitor and substrate of purified human immunodeficiency virus reverse transcriptase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2807%2956009-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Impaired replication of protease inhibitor-resistant HIV-1 in human thymus.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2807%2956009-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Stable rearrangements of the beta3-beta4 hairpin loop of HIV-1 reverse transcriptase in plasma viruses from patients receiving combination therapy.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2807%2956009-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Locations of anti-AIDS drug binding sites and resistance mutations in the three-dimensional structure of HIV-1 reverse transcriptase. Implications for mechanisms of drug inhibition and resistance
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2807%2956009-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Variable sensitivity of CCR5-tropic human immunodeficiency virus type 1 isolates to inhibition by RANTES analogs
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2807%2956009-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The CC-chemokine RANTES increases the attachment of human immunodeficiency virus type 1 to target cells via glycosaminoglycans and also activates a signal transduction pathway that enhances viral infectivity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2807%2956009-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
HIV-1 escape from a small molecule, CCR5-specific entry inhibitor does not involve CXCR4 use
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2807%2956009-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Prevalence and characteristics of multinucleoside-resistant human immunodeficiency virus type 1 among European patients receiving combinations of nucleoside analogues
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2807%2956009-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Enhanced fidelity of 3TC-selected mutant HIV-1 reverse transcriptase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2807%2956009-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Selection of high-level resistance to human immunodeficiency virus type 1 protease inhibitors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2807%2956009-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Diminished replicative fitness of primary human immunodeficiency virus type 1 isolates harboring the K65R mutation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2807%2956009-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Emergence of resistant human immunodeficiency virus type 1 in patients receiving fusion inhibitor (T-20) monotherapy.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2807%2956009-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Reduced maximal inhibition in phenotypic susceptibility assays indicates that viral strains resistant to the CCR5 antagonist maraviroc utilize inhibitor-bound receptor for entry
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2807%2956009-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Molecular mechanisms of resistance to human immunodeficiency virus type 1 with reverse transcriptase mutations K65R and K65R+M184V and their effects on enzyme function and viral replication capacity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2807%2956009-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Activity of non-nucleoside reverse transcriptase inhibitors against HIV-2 and SIV
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2807%2956009-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Resistance of human immunodeficiency virus type 1 to the high-mannose binding agents cyanovirin N and concanavalin A.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2807%2956009-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Conserved folding in retroviral proteases: crystal structure of a synthetic HIV-1 protease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2807%2956009-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Structural analysis of reverse transcriptase mutations at codon 215 explains the predominance of T215Y over T215F in HIV-1 variants selected under antiretroviral therapy
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2807%2956009-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
In vitro development of resistance to human immunodeficiency virus protease inhibitor GW640385.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2807%2956009-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Isolation of TAK-779-resistant HIV-1 from an R5 HIV-1 GP120 V3 loop library
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2807%2956009-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Loss of viral fitness associated with multiple Gag and Gag-Pol processing defects in human immunodeficiency virus type 1 variants selected for resistance to protease inhibitors in vivo.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1054-3589%2807%2956009-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S1054-3589(07)56009-6
1 reference
stated in
Europe PubMed Central
PubMed publication ID
18086415
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18086415%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 December 2019
PubMed publication ID
18086415
1 reference
stated in
Europe PubMed Central
PubMed publication ID
18086415
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18086415%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 December 2019
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