(Q37053343)

17 August 2017

1 reference

title

Regulation of telomerase and telomeres: human tumor viruses take control (English)

1 reference

17 August 2017

Marcia Bellon

1

1 reference

PubMed ID

18182620

17 August 2017

Christophe Nicot

series ordinal

2

1 reference

PubMed ID

18182620

17 August 2017

language of work or name

English

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publication date

8 January 2008

1 reference

Journal of the National Cancer Institute

17 August 2017

1 reference

17 August 2017

100

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17 August 2017

98-108

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17 August 2017

2

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Human telomerase and its regulation

17 August 2017

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJM269

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJM269

hEST2, the putative human telomerase catalytic subunit gene, is up-regulated in tumor cells and during immortalization

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJM269

Telomerase catalytic subunit homologs from fission yeast and human

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJM269

Inhibition of human telomerase in immortal human cells leads to progressive telomere shortening and cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJM269

Homologous recombination generates T-loop-sized deletions at human telomeres

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJM269

Telomere maintenance by recombination in human cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJM269

Telomere maintenance through spatial control of telomeric proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJM269

Shelterin: the protein complex that shapes and safeguards human telomeres

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJM269

Telomerase expression in human somatic cells does not induce changes associated with a transformed phenotype

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJM269

Creation of human tumour cells with defined genetic elements

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJM269

Epstein-Barr virus and oncogenesis: from latent genes to tumours

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJM269

Immortalization of immunologically committed Epstein-Barr virus-transformed human B-lymphoblastoid cell lines accompanied by a strong telomerase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJM269

siRNA targeting LMP1-induced apoptosis in EBV-positive lymphoma cells is associated with inhibition of telomerase activity and expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJM269

hTERT inhibits the Epstein-Barr virus lytic cycle and promotes the proliferation of primary B lymphocytes: implications for EBV-driven lymphomagenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJM269

Steps involved in immortalization and tumorigenesis in human B-lymphoblastoid cell lines transformed by Epstein-Barr virus

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJM269

Clonal chromosomal aberrations accompanied by strong telomerase activity in immortalization of human B-lymphoblastoid cell lines transformed by Epstein-Barr virus

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJM269

Epstein-Barr virus: 40 years on

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJM269

Epstein-Barr virus latent membrane 2A (LMP2A) down-regulates telomerase reverse transcriptase (hTERT) in epithelial cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJM269

Telomere size and telomerase activity in Epstein-Barr virus (EBV)-positive and EBV-negative Burkitt's lymphoma cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJM269

Epstein-Barr virus promotes genomic instability in Burkitt's lymphoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJM269

The pleiotropic effects of Kaposi's sarcoma herpesvirus

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJM269

Transformation of primary human endothelial cells by Kaposi's sarcoma-associated herpesvirus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJM269

Efficient persistence of extrachromosomal KSHV DNA mediated by latency-associated nuclear antigen

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJM269

The latency-associated nuclear antigen of Kaposi's sarcoma-associated herpesvirus supports latent DNA replication in dividing cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJM269

Latency-associated nuclear antigen of Kaposi's sarcoma-associated herpesvirus up-regulates transcription of human telomerase reverse transcriptase promoter through interaction with transcription factor Sp1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJM269

Kaposi's sarcoma associated herpesvirus G protein-coupled receptor immortalizes human endothelial cells by activation of the VEGF receptor-2/ KDR.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJM269

Persistent human papillomavirus infection and cervical neoplasia

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJM269

Prospects for cervical cancer prevention by human papillomavirus vaccination

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJM269

Telomerase activation by the E6 gene product of human papillomavirus type 16.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJM269

Papillomaviruses and cancer: from basic studies to clinical application

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJM269

Identification of a novel telomerase repressor that interacts with the human papillomavirus type-16 E6/E6-AP complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJM269

Binding of human papillomavirus type 16 E6 to E6AP is not required for activation of hTERT

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJM269

Chromosomal instability is correlated with telomere erosion and inactivation of G2 checkpoint function in human fibroblasts expressing human papillomavirus type 16 E6 oncoprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJM269

Telomere attrition predominantly occurs in precursor lesions during in vivo carcinogenic process of the uterine cervix.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJM269

The papillomavirus E2 proteins: structure, function, and biology

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJM269

Molecular viral oncology of hepatocellular carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJM269

The preS2/S region of integrated hepatitis B virus DNA encodes a transcriptional transactivator

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJM269

Hepatitis B virus transactivator HBx uses a tumour promoter signalling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJM269

Effects of hepatitis B virus X protein on human telomerase reverse transcriptase expression and activity in hepatoma cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJM269

In vitro transfection of the hepatitis B virus PreS2 gene into the human hepatocarcinoma cell line HepG2 induces upregulation of human telomerase reverse transcriptase

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJM269

Increased expression of telomere length regulating factors TRF1, TRF2 and TIN2 in patients with adult T-cell leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJM269

Telomerase activity and telomere length as prognostic factors of adult T-cell leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJM269

Correlation of telomerase activity with development and progression of adult T-cell leukemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJM269

Telomerase activity of human peripheral blood mononuclear cells in the course of HTLV type 1 infection in vitro.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJM269

Persistent inhibition of telomerase reprograms adult T-cell leukemia to p53-dependent senescence

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJM269

Transcriptional activation of hTERT through the NF-kappaB pathway in HTLV-I-transformed cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJM269

Inactivation of hTERT transcription by Tax.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJM269

Telomeres: prognostic markers for solid tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJM269

Direct activation of TERT transcription by c-MYC.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJM269

Sp1 cooperates with c-Myc to activate transcription of the human telomerase reverse transcriptase gene (hTERT).

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJM269

Telomerase activation by human papillomavirus type 16 E6 protein: induction of human telomerase reverse transcriptase expression through Myc and GC-rich Sp1 binding sites

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJM269

Human papillomavirus E6 and Myc proteins associate in vivo and bind to and cooperatively activate the telomerase reverse transcriptase promoter

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJM269

The E6AP ubiquitin ligase is required for transactivation of the hTERT promoter by the human papillomavirus E6 oncoprotein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJM269

BRCA1 Inhibition of Telomerase Activity in Cultured Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJM269

Basal and human papillomavirus E6 oncoprotein-induced degradation of Myc proteins by the ubiquitin pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJM269

TRRAP-dependent and TRRAP-independent transcriptional activation by Myc family oncoproteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJM269

Regulation of telomerase reverse transcriptase gene activity by upstream stimulatory factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJM269

Human papillomavirus type 16 E6 activates TERT gene transcription through induction of c-Myc and release of USF-mediated repression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJM269

Function of AP-1 in transcription of the telomerase reverse transcriptase gene (TERT) in human and mouse cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJM269

Epstein-Barr virus latent membrane protein-1 triggers AP-1 activity via the c-Jun N-terminal kinase cascade

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJM269

Latent membrane protein 1 encoded by Epstein-Barr virus induces telomerase activity via p16INK4A/Rb/E2F1 and JNK signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJM269

Histone deacetylation is involved in the transcriptional repression of hTERT in normal human cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJM269

The histone deacetylase inhibitor trichostatin A derepresses the telomerase reverse transcriptase (hTERT) gene in human cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJM269

HPV16-E6 associated hTERT promoter acetylation is E6AP dependent, increased in later passage cells and enhanced by loss of p300.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJM269

Tumor-specific activation of hTERT-derived promoters by tumor suppressive E1A-mutants involves recruitment of p300/CBP/HAT and suppression of HDAC-1 and defines a combined tumor targeting and suppression system

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJM269

Mitogen-activated protein kinase cascade-mediated histone H3 phosphorylation is critical for telomerase reverse transcriptase expression/telomerase activation induced by proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJM269

Activation of the cJun N-terminal kinase (JNK) pathway by the Epstein-Barr virus-encoded latent membrane protein 1 (LMP1).

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJM269

ORF36 protein kinase of Kaposi's sarcoma herpesvirus activates the c-Jun N-terminal kinase signaling pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJM269

Methylation status and expression of human telomerase reverse transcriptase in ovarian and cervical cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJM269

Hypermethylation of the human telomerase catalytic subunit (hTERT) gene correlates with telomerase activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJM269

Integrations of the hepatitis B virus (HBV) and human papillomavirus (HPV) into the human telomerase reverse transcriptase (hTERT) gene in liver and cervical cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJM269

Hepatitis B virus-related insertional mutagenesis occurs frequently in human liver cancers and recurrently targets human telomerase gene.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJM269

Transcriptional regulation of the telomerase hTERT gene as a target for cellular and viral oncogenic mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJM269

cis-Activation of the human telomerase gene (hTERT) by the hepatitis B virus genome

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJM269

Gain of chromosome 3q defines the transition from severe dysplasia to invasive carcinoma of the uterine cervix

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJM269

Genomic integration of oncogenic HPV and gain of the human telomerase gene TERC at 3q26 are strongly associated events in the progression of uterine cervical dysplasia to invasive cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJM269

hTERT phosphorylation by PKC is essential for telomerase holoprotein integrity and enzyme activity in head neck cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJM269

Protein kinase C modulates telomerase activity in human cervical cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJM269

Epstein-Barr virus encoded latent membrane protein 1 modulates nuclear translocation of telomerase reverse transcriptase protein by activating nuclear factor-kappaB p65 in human nasopharyngeal carcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJM269

NFX1-123 and poly(A) binding proteins synergistically augment activation of telomerase in human papillomavirus type 16 E6-expressing cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJM269

Control of human telomere length by TRF1 and TRF2

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJM269

p53- and ATM-dependent apoptosis induced by telomeres lacking TRF2

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJM269

TIN2 mediates functions of TRF2 at human telomeres

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJM269

Telomerase activity in B-cell non-Hodgkin lymphomas is regulated by hTERT transcription and correlated with telomere-binding protein expression but uncoupled from proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJM269

The Pin2/TRF1-interacting protein PinX1 is a potent telomerase inhibitor

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJM269

Multiple tumor suppressor pathways negatively regulate telomerase

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJM269

Papillomavirus E2 induces senescence in HPV-positive cells via pRB- and p21(CIP)-dependent pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJM269

Human papillomavirus E2 down-regulates the human telomerase reverse transcriptase promoter

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJM269

Regulation of telomerase by human papillomaviruses.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJM269

The bZIP transactivator of Epstein-Barr virus, BZLF1, functionally and physically interacts with the p65 subunit of NF-kappa B

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJM269

The Human Herpes Virus 8-Encoded Viral FLICE-inhibitory Protein Induces Cellular Transformation via NF-κB Activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJM269

Topology of the Membrane-Associated Hepatitis C Virus Protein NS4B

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJM269

Hepatitis C virus NS5A: tales of a promiscuous protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2FDJM269

21 January 2018

Identifiers

DOI

10.1093/JNCI/DJM269

1 reference

17 August 2017

1 reference

PubMed ID

18182620