(Q37062077)

18 August 2017

Differential impact of the CD45 juxtamembrane wedge on central and peripheral T cell receptor responses (English)

1 reference

18 August 2017

10

Arthur Weiss

1 reference

18 August 2017

9

Jorge R Oksenberg

1 reference

18 August 2017

Michelle L Hermiston

1

1 reference

18 August 2017

Julie Zikherman

2

1 reference

18 August 2017

Allison L Tan

3

1 reference

18 August 2017

Viola C Lam

4

1 reference

18 August 2017

Nicole M Cresalia

5

1 reference

18 August 2017

Nir Oksenberg

6

1 reference

18 August 2017

Nira Goren

7

1 reference

18 August 2017

David Brassat

8

1 reference

18 August 2017

language of work or name

English

0 references

publication date

7 January 2009

1 reference

18 August 2017

6

1 reference

Proceedings of the National Academy of Sciences of the United States of America

inferred from page(s)

published in

1 reference

18 August 2017

106

1 reference

18 August 2017

2

1 reference

18 August 2017

546-551

1 reference

Lck-dependent Fyn activation requires C terminus-dependent targeting of kinase-active Lck to lipid rafts

18 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2626740

Changes in the role of the CD45 protein tyrosine phosphatase in regulating Lck tyrosine phosphorylation during thymic development

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2626740

PAG-associated FynT regulates calcium signaling and promotes anergy in T lymphocytes

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2626740

Lck regulates the threshold of activation in primary T cells, while both Lck and Fyn contribute to the magnitude of the extracellular signal-related kinase response

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2626740

Strength of signal: a fundamental mechanism for cell fate specification

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2626740

Altered CD45 expression and disease.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2626740

CD45: all is not yet crystal clear

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2626740

Structural basis for the function and regulation of the receptor protein tyrosine phosphatase CD45

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2626740

Function of the Src-family kinases, Lck and Fyn, in T-cell development and activation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2626740

Altered lipid raft-associated signaling and ganglioside expression in T lymphocytes from patients with systemic lupus erythematosus

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2626740

Surface T‐cell antigen receptor expression and availability for long‐term antigenic signaling

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2626740

The influence of the src-family kinases, Lck and Fyn, on T cell differentiation, survival and activation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2626740

A mouse with a loss-of-function mutation in the c-Cbl TKB domain shows perturbed thymocyte signaling without enhancing the activity of the ZAP-70 tyrosine kinase

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2626740

CD45: a critical regulator of signaling thresholds in immune cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2626740

T cell response in experimental autoimmune encephalomyelitis (EAE): role of self and cross-reactive antigens in shaping, tuning, and regulating the autopathogenic T cell repertoire

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2626740

Selecting and maintaining a diverse T-cell repertoire

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2626740

Dimerization-induced inhibition of receptor protein tyrosine phosphatase function through an inhibitory wedge

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2626740

Structural basis for inhibition of receptor protein-tyrosine phosphatase-alpha by dimerization

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2626740

CD45-null transgenic mice reveal a positive regulatory role for CD45 in early thymocyte development, in the selection of CD4+CD8+ thymocytes, and B cell maturation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2626740

Normal B lymphocyte development but impaired T cell maturation in CD45-exon6 protein tyrosine phosphatase-deficient mice

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2626740

Differential association of CD45 isoforms with CD4 and CD8 regulates the actions of specific pools of p56lck tyrosine kinase in T cell antigen receptor signal transduction

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2626740

Switching signals on or off by receptor dimerization

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2626740

Characterization of recombinant CD45 cytoplasmic domain proteins. Evidence for intramolecular and intermolecular interactions

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2626740

Ligand-mediated negative regulation of a chimeric transmembrane receptor tyrosine phosphatase

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2626740

Tolerance in T-cell-receptor transgenic mice involves deletion of nonmature CD4+8+ thymocytes

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2626740

Induction by antigen of intrathymic apoptosis of CD4+CD8+TCRlo thymocytes in vivo

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2626740

Evidence for monomeric and dimeric forms of CD45 associated with a 30-kDa phosphorylated protein

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2626740

Structurally distinct phosphatases CD45 and CD148 both regulate B cell and macrophage immunoreceptor signaling.

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2626740

The differential regulation of Lck kinase phosphorylation sites by CD45 is critical for T cell receptor signaling responses.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2626740

The juxtamembrane wedge negatively regulates CD45 function in B cells.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2626740

H2O2-induced intermolecular disulfide bond formation between receptor protein-tyrosine phosphatases

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2626740

Negative regulation of CD45 by differential homodimerization of the alternatively spliced isoforms

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2626740

An inactivating point mutation in the inhibitory wedge of CD45 causes lymphoproliferation and autoimmunity

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2626740

TCR affinity and negative regulation limit autoimmunity

4 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.0811647106

Defective TCR expression in transgenic mice constructed using cDNA-based α- and β-chain genes under the control of heterologous regulatory elements

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.0811647106

Altered thymic T-cell selection due to a mutation of the ZAP-70 gene causes autoimmune arthritis in mice

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.0811647106

Alterations in the level of CD45 surface expression affect the outcome of thymic selection

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19129486

12 December 2020

inferred from PubMed ID database lookup

Cutting edge: the CD45 tyrosine phosphatase is an inhibitor of Lck activity in thymocytes

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19129486

12 December 2020

inferred from PubMed ID database lookup

pp59fyn mutant mice display differential signaling in thymocytes and peripheral T cells

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19129486

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1073/PNAS.0811647106

1 reference

18 August 2017

0 references

1 reference

18 August 2017

PubMed publication ID

19129486

1 reference