(Q37070205)

18 August 2017

Toll-like receptors--taking an evolutionary approach (English)

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18 August 2017

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2

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18 August 2017

François Leulier

1

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18 August 2017

1 March 2008

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18 August 2017

Nature Reviews Genetics

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18 August 2017

9

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18 August 2017

165-178

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18 August 2017

3

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https://scigraph.springernature.com/pub.10.1038/nrg2303

18 August 2017

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cites work

Establishment of dorsal-ventral polarity in the Drosophila embryo: genetic studies on the role of the Toll gene product.

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Pathogen recognition and innate immunity

31 March 2020

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Toll-like receptors: linking innate and adaptive immunity

31 March 2020

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The dorsoventral regulatory gene cassette spätzle/Toll/cactus controls the potent antifungal response in Drosophila adults

31 March 2020

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Structural and functional diversity in the leucine-rich repeat family of proteins

31 March 2020

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The leucine-rich repeat as a protein recognition motif

31 March 2020

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The molecular structure of the Toll-like receptor 3 ligand-binding domain.

31 March 2020

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Crystal structure of human toll-like receptor 3 (TLR3) ectodomain

31 March 2020

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Binding of the Drosophila cytokine Spätzle to Toll is direct and establishes signaling

31 March 2020

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Identification of a Sequence in Human Toll-like Receptor 5 Required for the Binding of Gram-negative Flagellin

31 March 2020

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A conserved surface on Toll-like receptor 5 recognizes bacterial flagellin

31 March 2020

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Crystal structure of the TLR1-TLR2 heterodimer induced by binding of a tri-acylated lipopeptide

31 March 2020

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Direct evidence that toll-like receptor 9 (TLR9) functionally binds plasmid DNA by specific cytosine-phosphate-guanine motif recognition.

31 March 2020

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Toll-like receptor 9 binds single-stranded CpG-DNA in a sequence- and pH-dependent manner.

31 March 2020

1 reference

NACHT-LRR proteins (NLRs) in bacterial infection and immunity

31 March 2020

1 reference

NLRs join TLRs as innate sensors of pathogens

31 March 2020

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Plant NBS-LRR proteins in pathogen sensing and host defense

31 March 2020

1 reference

TIR, CARD and PYRIN: three domains for an antimicrobial triad

31 March 2020

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A46R and A52R from vaccinia virus are antagonists of host IL-1 and toll-like receptor signaling.

31 March 2020

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A conserved signaling pathway: the Drosophila toll-dorsal pathway

31 March 2020

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A human homologue of the Drosophila Toll protein signals activation of adaptive immunity

31 March 2020

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Structural basis for signal transduction by the Toll/interleukin-1 receptor domains

31 March 2020

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The interleukin-1 receptor family

31 March 2020

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The innate immune repertoire in cnidaria--ancestral complexity and stochastic gene loss.

31 March 2020

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Are innate immune signaling pathways in plants and animals conserved?

31 March 2020

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Multigene analyses of bilaterian animals corroborate the monophyly of Ecdysozoa, Lophotrochozoa, and Protostomia

31 March 2020

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Sea Anemone Genome Reveals Ancestral Eumetazoan Gene Repertoire and Genomic Organization

31 March 2020

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Rel homology domain-containing transcription factors in the cnidarian Nematostella vectensis

31 March 2020

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Innate immune defense of the sponge Suberites domuncula against bacteria involves a MyD88-dependent signaling pathway. Induction of a perforin-like molecule

31 March 2020

1 reference

Toll-like receptors are part of the innate immune defense system of sponges (demospongiae: Porifera).

31 March 2020

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Innate immunity: an overview

31 March 2020

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Biology of Toll receptors: lessons from insects and mammals

31 March 2020

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Independent evolution of Toll and related genes in insects and mammals

31 March 2020

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Molecular evolution of the NF-kappaB signaling system.

31 March 2020

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Origin of Toll-like receptor-mediated innate immunity.

31 March 2020

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The evolution of vertebrate Toll-like receptors

31 March 2020

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Dorsoventral axis formation in the Drosophila embryo--shaping and transducing a morphogen gradient

31 March 2020

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The origin of dorsoventral polarity in Drosophila.

31 March 2020

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Genetic and molecular characterization of tube, a Drosophila gene maternally required for embryonic dorsoventral polarity.

31 March 2020

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The Drosophila toll gene functions zygotically and is necessary for proper motoneuron and muscle development.

31 March 2020

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The Toll pathway is required in the epidermis for muscle development in the Drosophila embryo.

31 March 2020

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Expression, regulation, and requirement of the toll transmembrane protein during dorsal vessel formation in Drosophila melanogaster

31 March 2020

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The Drosophila membrane receptor Toll can function to promote cellular adhesion.

31 March 2020

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Drosophila MyD88 is required for the response to fungal and Gram-positive bacterial infections

31 March 2020

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Cutting edge: the toll pathway is required for resistance to gram-positive bacterial infections in Drosophila.

31 March 2020

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The Toll and Imd pathways are the major regulators of the immune response in Drosophila

31 March 2020

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The host defense of Drosophila melanogaster

31 March 2020

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Sensing infection in Drosophila: Toll and beyond

31 March 2020

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Cellular immune response to parasite infection in the Drosophila lymph gland is developmentally regulated

31 March 2020

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Tissue and stage-specific expression of the Tolls in Drosophila embryos.

31 March 2020

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18 wheeler regulates apical constriction of salivary gland cells via the Rho-GTPase-signaling pathway

31 March 2020

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Expression of 18-wheeler in the follicle cell epithelium affects cell migration and egg morphology in Drosophila

31 March 2020

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Induction of neuron-specific glycosylation by Tollo/Toll-8, a Drosophila Toll-like receptor expressed in non-neural cells

31 March 2020

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Dynamic developmental elaboration of N-linked glycan complexity in the Drosophila melanogaster embryo

31 March 2020

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31 March 2020

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Genetic variation in Drosophila melanogaster resistance to infection: a comparison across bacteria

31 March 2020

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Tehao functions in the Toll pathway in Drosophila melanogaster: possible roles in development and innate immunity

31 March 2020

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The Drosophila Toll-9 activates a constitutive antimicrobial defense

31 March 2020

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Comparative genomics of the eukaryotes

31 March 2020

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31 March 2020

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Immune pathways and defence mechanisms in honey bees Apis mellifera.

31 March 2020

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Evolutionary dynamics of immune-related genes and pathways in disease-vector mosquitoes

31 March 2020

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Comparative genomic analysis of the Tribolium immune system

31 March 2020

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Using FlyAtlas to identify better Drosophila melanogaster models of human disease

31 March 2020

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A toll receptor and a cytokine, Toll5A and Spz1C, are involved in toll antifungal immune signaling in the mosquito Aedes aegypti

31 March 2020

1 reference

A reverse genetic analysis of components of the Toll signaling pathway in Caenorhabditis elegans

31 March 2020

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A conserved Toll-like receptor is required for Caenorhabditis elegans innate immunity

31 March 2020

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A Toll-interleukin 1 repeat protein at the synapse specifies asymmetric odorant receptor expression via ASK1 MAPKKK signaling.

31 March 2020

1 reference

TLR-independent control of innate immunity in Caenorhabditis elegans by the TIR domain adaptor protein TIR-1, an ortholog of human SARM.

31 March 2020

1 reference

Requirement for a conserved Toll/interleukin-1 resistance domain protein in the Caenorhabditis elegans immune response

31 March 2020

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Genetic analysis of host resistance: Toll-like receptor signaling and immunity at large

31 March 2020

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The family of five: TIR-domain-containing adaptors in Toll-like receptor signalling

31 March 2020

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31 March 2020

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Toll-like receptors in innate immunity

31 March 2020

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Toll-like receptors: linking innate and adaptive immunity

31 March 2020

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Toll-like receptor control of the adaptive immune responses

31 March 2020

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Toll-like receptors on regulatory T cells: expanding immune regulation

31 March 2020

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Toll-like receptor 8 functions as a negative regulator of neurite outgrowth and inducer of neuronal apoptosis

31 March 2020

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Toll-like receptor 3 is a potent negative regulator of axonal growth in mammals

31 March 2020

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Toll-like receptors modulate adult hippocampal neurogenesis

31 March 2020

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Toll-like receptors in the pathogenesis of human disease

31 March 2020

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Innate immunogenetics: a tool for exploring new frontiers of host defence

31 March 2020

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Pyogenic bacterial infections in humans with IRAK-4 deficiency

31 March 2020

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Herpes simplex virus encephalitis in human UNC-93B deficiency

31 March 2020

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TLR3 deficiency in patients with herpes simplex encephalitis

31 March 2020

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Inherited disorders of human Toll-like receptor signaling: immunological implications.

31 March 2020

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Comparative studies on the toxicity of Escherichia coli lipopolysaccharide endotoxin in various animal species

31 March 2020

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Endotoxin recognition: in fish or not in fish?

31 March 2020

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Lamprey TLRs with properties distinct from those of the variable lymphocyte receptors

31 March 2020

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MyD88 innate immune function in a zebrafish embryo infection model

31 March 2020

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Genomic insights into the immune system of the sea urchin

31 March 2020

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The immune gene repertoire encoded in the purple sea urchin genome.

31 March 2020

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THE EVOLUTION OF ADAPTIVE IMMUNITY

31 March 2020

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Deuterostome phylogeny reveals monophyletic chordates and the new phylum Xenoturbellida

31 March 2020

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Genomic analysis of immunity in a Urochordate and the emergence of the vertebrate immune system: “waiting for Godot”

31 March 2020

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Recognition strategies in the innate immune system of ancestral chordates

31 March 2020

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Protein phylogenies provide evidence of a radical discontinuity between arthropod and vertebrate immune systems

31 March 2020

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Cell-free immunity in insects

31 March 2020

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Defective LPS Signaling in C3H/HeJ and C57BL/10ScCr Mice: Mutations in Tlr4 Gene

31 March 2020

1 reference

Endotoxin-tolerant mice have mutations in Toll-like receptor 4 (Tlr4)

31 March 2020

1 reference

Cutting edge: preferentially the R-stereoisomer of the mycoplasmal lipopeptide macrophage-activating lipopeptide-2 activates immune cells through a toll-like receptor 2- and MyD88-dependent signaling pathway

31 March 2020

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Discrimination of bacterial lipoproteins by Toll-like receptor 6

31 March 2020

1 reference

Cutting edge: role of Toll-like receptor 1 in mediating immune response to microbial lipoproteins

31 March 2020

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The innate immune response to bacterial flagellin is mediated by Toll-like receptor 5

31 March 2020

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A toll-like receptor that prevents infection by uropathogenic bacteria

31 March 2020

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TLR11 activation of dendritic cells by a protozoan profilin-like protein.

31 March 2020

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Recognition of double-stranded RNA and activation of NF-kappaB by Toll-like receptor 3

31 March 2020

1 reference

Small anti-viral compounds activate immune cells via the TLR7 MyD88-dependent signaling pathway

31 March 2020

1 reference

The Toll‐like receptor 7 (TLR7)‐specific stimulus loxoribine uncovers a strong relationship within the TLR7, 8 and 9 subfamily

31 March 2020

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Sequence-specific potent induction of IFN-alpha by short interfering RNA in plasmacytoid dendritic cells through TLR7

31 March 2020

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Human TLR7 or TLR8 independently confer responsiveness to the antiviral compound R-848

31 March 2020

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Species-specific recognition of single-stranded RNA via toll-like receptor 7 and 8

31 March 2020

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A Toll-like receptor recognizes bacterial DNA

31 March 2020

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Toll-like receptor 9-mediated recognition of Herpes simplex virus-2 by plasmacytoid dendritic cells

31 March 2020

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Toll-like receptor 9 mediates innate immune activation by the malaria pigment hemozoin

31 March 2020

1 reference

Identifying components of the NF-kappaB pathway in the beneficial Euprymna scolopes-Vibrio fischeri light organ symbiosis

31 March 2020

1 reference

Molecular cloning and expression of a Toll receptor gene homologue from Zhikong Scallop, Chlamys farreri

31 March 2020

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Differential expression of caudal and dorsal genes in the teloblast lineages of the oligochaete annelid Tubifex tubifex.

31 March 2020

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Dorsal and snail homologs in leech development

31 March 2020

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The human adaptor SARM negatively regulates adaptor protein TRIF-dependent Toll-like receptor signaling.

31 March 2020

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The new animal phylogeny: reliability and implications

31 March 2020

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31 March 2020

Identifiers

DOI

10.1038/NRG2303

1 reference

18 August 2017

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PubMed ID

18227810