(Q37094690)

18 August 2017

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title

Clinical potential of targeting Bruton's tyrosine kinase (English)

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18 August 2017

1

Fatih M Uckun

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18 August 2017

publication date

1 January 2008

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International Reviews of Immunology

18 August 2017

published in

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18 August 2017

volume

27

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18 August 2017

issue

1-2

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18 August 2017

page(s)

43-69

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Childhood acute lymphoblastic leukaemia and relapse

18 August 2017

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21 January 2018

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Bruton's tyrosine kinase as an inhibitor of the Fas/CD95 death-inducing signaling complex.

21 January 2018

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Bruton's tyrosine kinase (BTK) as a dual-function regulator of apoptosis

21 January 2018

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BTK as a mediator of radiation-induced apoptosis in DT-40 lymphoma B cells

21 January 2018

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Bruton's tyrosine kinase links the B cell receptor to nuclear factor kappaB activation

21 January 2018

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Bruton's tyrosine kinase regulates apoptosis and JNK/SAPK kinase activity

21 January 2018

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Transcription factor STAT5A is a substrate of Bruton's tyrosine kinase in B cells

21 January 2018

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Phosphatidylinositol 3-kinase-dependent membrane association of the Bruton's tyrosine kinase pleckstrin homology domain visualized in single living cells

21 January 2018

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Phospholipase C-gamma 2 couples Bruton's tyrosine kinase to the NF-kappaB signaling pathway in B lymphocytes

21 January 2018

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Signaling network of the Btk family kinases

21 January 2018

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21 January 2018

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Btk expression is controlled by Oct and BOB.1/OBF.1.

21 January 2018

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Enrichment of nucleofected primary human CD4+ T cells: a novel and efficient method for studying gene function and role in human primary T helper cell differentiation.

21 January 2018

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Antisense- and RNA interference-based therapeutic strategies in allergy.

21 January 2018

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Characterization of microsomal fraction proteome in human lymphoblasts reveals the down-regulation of galectin-1 by interleukin-12.

21 January 2018

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Differential expression and molecular characterisation of Lmo7, Myo1e, Sash1, and Mcoln2 genes in Btk-defective B-cells

21 January 2018

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Bruton's tyrosine kinase is involved in p65-mediated transactivation and phosphorylation of p65 on serine 536 during NFkappaB activation by lipopolysaccharide

21 January 2018

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Bruton's tyrosine kinase regulates immunoglobulin promoter activation in association with the transcription factor Bright

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Mechanism of B-cell receptor-induced phosphorylation and activation of phospholipase C-gamma2.

21 January 2018

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BCR targets cyclin D2 via Btk and the p85alpha subunit of PI3-K to induce cell cycle progression in primary mouse B cells

21 January 2018

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Deficiency of Bruton's tyrosine kinase in B cell precursor leukemia cells

21 January 2018

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Genetic analysis of patients with defects in early B-cell development

21 January 2018

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Bruton's tyrosine kinase: cell biology, sequence conservation, mutation spectrum, siRNA modifications, and expression profiling.

21 January 2018

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X linked agammaglobulinaemia and rheumatoid arthritis

21 January 2018

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Bruton's tyrosine kinase together with PI 3-kinase are part of Toll-like receptor 2 multiprotein complex and mediate LTA induced Toll-like receptor 2 responses in macrophages

21 January 2018

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Bruton's tyrosine kinase is required for lipopolysaccharide-induced tumor necrosis factor alpha production

21 January 2018

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Signaling through CD16b in human neutrophils involves the Tec family of tyrosine kinases

21 January 2018

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Different roles for non-receptor tyrosine kinases in arachidonate release induced by zymosan and Staphylococcus aureus in macrophages

21 January 2018

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Silencing of Bruton's tyrosine kinase (Btk) using short interfering RNA duplexes (siRNA)

21 January 2018

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Long-term follow-up of patients who achieved complete remission after donor leukocyte infusions.

21 January 2018

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Non-myeloablative allogeneic stem cell transplantation focusing on immunotherapy of life-threatening malignant and non-malignant diseases

21 January 2018

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Intentional induction of mixed chimerism and achievement of antitumor responses after nonmyeloablative conditioning therapy and HLA-matched donor bone marrow transplantation for refractory hematologic malignancies

21 January 2018

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Transplantation of CD34+ hematopoietic progenitor cells

21 January 2018

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Dual targeting of Bruton's tyrosine kinase and Janus kinase 3 with rationally designed inhibitors prevents graft-versus-host disease (GVHD) in a murine allogeneic bone marrow transplantation model

21 January 2018

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Platelets and angiogenesis in malignancy.

21 January 2018

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Warfarin versus low-molecular-weight heparin therapy in cancer patients

21 January 2018

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Aspirin and platelet-lowering agents for the prevention of vascular complications in essential thrombocythemia

21 January 2018

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21 January 2018

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The in vivo pharmacological profile of CS-747, a novel antiplatelet agent with platelet ADP receptor antagonist properties

21 January 2018

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Synthetic inhibitors of platelet glycoprotein IIb/IIIa in clinical development

21 January 2018

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Glycoprotein VI is the collagen receptor in platelets which underlies tyrosine phosphorylation of the Fc receptor gamma-chain

21 January 2018

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A novel association of Fc receptor gamma-chain with glycoprotein VI and their co-expression as a collagen receptor in human platelets

21 January 2018

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A role for Bruton's tyrosine kinase (Btk) in platelet activation by collagen.

21 January 2018

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Platelets activated by collagen through the immunoreceptor tyrosine-based activation motif in the Fc receptor gamma-chain play a pivotal role in the development of myocardial ischemia-reperfusion injury

21 January 2018

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Platelet adhesion signalling and the regulation of thrombus formation

21 January 2018

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Collagen receptor signalling in platelets: extending the role of the ITAM.

21 January 2018

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The Wiskott-Aldrich syndrome protein (WASP): roles in signaling and cytoskeletal organization

21 January 2018

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Bruton's tyrosine kinase associates with the actin-based cytoskeleton in activated platelets

21 January 2018

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Bruton's tyrosine kinase is a substrate of calpain in human platelets

21 January 2018

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Ca2+-independent activation of Bruton's tyrosine kinase is required for store-mediated Ca2+ entry in human platelets

21 January 2018

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Interaction of Bruton's tyrosine kinase and protein kinase Ctheta in platelets. Cross-talk between tyrosine and serine/threonine kinases

21 January 2018

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A prospective cohort study determining the prevalence of thrombotic events in children with acute lymphoblastic leukemia and a central venous line who are treated with L-asparaginase: results of the Prophylactic Antithrombin Replacement in Kids with

21 January 2018

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Allogeneic Stem-Cell Transplantation May Overcome the Adverse Prognosis of UnmutatedVHGene in Patients With Chronic Lymphocytic Leukemia

21 January 2018

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c-Abl Expression in Chronic Lymphocytic Leukemia Cells: Clinical and Therapeutic Implications

21 January 2018

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Association analysis of common variants of STAT6, GATA3, and STAT4 to asthma and high serum IgE phenotypes

21 January 2018

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Variability in the Degree of Expression of Phosphorylated I B in Chronic Lymphocytic Leukemia Cases With Nodal Involvement

21 January 2018

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10.1080/08830180701784588

21 January 2018

Identifiers

DOI

1 reference

18 August 2017

1 reference