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Adipose tissue insulin sensitivity and macrophage recruitment: Does PI3K pick the pathway?
scientific article published on 16 April 2013
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scholarly article
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Europe PubMed Central
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3756101
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23991359%20AND%20SRC:MED&resulttype=core&format=json
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8 March 2020
title
Adipose tissue insulin sensitivity and macrophage recruitment: Does PI3K pick the pathway?
(English)
1 reference
stated in
Europe PubMed Central
PMCID
3756101
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23991359%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 March 2020
main subject
macrophage
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preproinsulin
1 reference
based on heuristic
inferred from title
author
Carrie E McCurdy
series ordinal
1
1 reference
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Europe PubMed Central
PMCID
3756101
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23991359%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 March 2020
author name string
Dwight J Klemm
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2
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Europe PubMed Central
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3756101
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8 March 2020
publication date
16 April 2013
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3756101
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8 March 2020
published in
Adipocyte
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3756101
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8 March 2020
volume
2
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Europe PubMed Central
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3756101
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8 March 2020
issue
3
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Europe PubMed Central
PMCID
3756101
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23991359%20AND%20SRC:MED&resulttype=core&format=json
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8 March 2020
page(s)
135-142
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Europe PubMed Central
PMCID
3756101
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8 March 2020
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Protein kinase C-delta and phosphatidylinositol 3-kinase/Akt activate mammalian target of rapamycin to modulate NF-kappaB activation and intercellular adhesion molecule-1 (ICAM-1) expression in endothelial cells
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3756101
retrieved
27 June 2018
Resveratrol modulates interleukin-1β-induced phosphatidylinositol 3-kinase and nuclear factor κB signaling pathways in human tenocytes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3756101
retrieved
27 June 2018
Curcumin modulates nuclear factor kappaB (NF-kappaB)-mediated inflammation in human tenocytes in vitro: role of the phosphatidylinositol 3-kinase/Akt pathway
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3756101
retrieved
27 June 2018
Insulin regulates adipocyte lipolysis via an Akt-independent signaling pathway
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3756101
retrieved
27 June 2018
Transcriptional activation of peroxisome proliferator-activated receptor-gamma requires activation of both protein kinase A and Akt during adipocyte differentiation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3756101
retrieved
27 June 2018
Hormonal induction of adipogenesis induces Skp2 expression through PI3K and MAPK pathways
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3756101
retrieved
27 June 2018
Palmitate activates the NF-kappaB transcription factor and induces IL-6 and TNFalpha expression in 3T3-L1 adipocytes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3756101
retrieved
27 June 2018
Increased p85/55/50 expression and decreased phosphotidylinositol 3-kinase activity in insulin-resistant human skeletal muscle
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3756101
retrieved
27 June 2018
Cell type-specific expression of the IkappaB kinases determines the significance of phosphatidylinositol 3-kinase/Akt signaling to NF-kappa B activation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3756101
retrieved
27 June 2018
p110beta is up-regulated during differentiation of 3T3-L1 cells and contributes to the highly insulin-responsive glucose transport activity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3756101
retrieved
27 June 2018
Overnight lowering of free fatty acids with Acipimox improves insulin resistance and glucose tolerance in obese diabetic and nondiabetic subjects.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3756101
retrieved
27 June 2018
Activation of protein kinase B and induction of adipogenesis by insulin in 3T3-L1 preadipocytes: contribution of phosphoinositide-3,4,5-trisphosphate versus phosphoinositide-3,4-bisphosphate
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3756101
retrieved
27 June 2018
Wortmannin, a specific phosphatidylinositol 3-kinase inhibitor, inhibits adipocytic differentiation of 3T3-L1 cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3756101
retrieved
27 June 2018
Arctigenin ameliorates inflammation in vitro and in vivo by inhibiting the PI3K/AKT pathway and polarizing M1 macrophages to M2-like macrophages
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3756101
retrieved
3 September 2018
Activation of the PI3K pathway increases TLR-induced TNF-α and IL-6 but reduces IL-1β production in mast cells.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3756101
retrieved
3 September 2018
Morphological characteristics of abdominal adipose tissue in normal-weight and obese women of different metabolic profiles
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3756101
retrieved
3 September 2018
Prolonged exposure to high insulin impairs the endothelial PI3-kinase/Akt/nitric oxide signalling.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3756101
retrieved
3 September 2018
ICOS ligation recruits the p50alpha PI3K regulatory subunit to the immunological synapse.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3756101
retrieved
3 September 2018
Critical role of phosphoinositide 3-kinase cascade in adipogenesis of human mesenchymal stem cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3756101
retrieved
3 September 2018
Endothelial PI 3-kinase activity regulates lymphocyte diapedesis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3756101
retrieved
3 September 2018
Nutritional upregulation of p85alpha expression is an early molecular manifestation of insulin resistance
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3756101
retrieved
3 September 2018
Adipose-specific overexpression of GLUT4 reverses insulin resistance and diabetes in mice lacking GLUT4 selectively in muscle
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3756101
retrieved
3 September 2018
Reversal of insulin resistance postpartum is linked to enhanced skeletal muscle insulin signaling
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3756101
retrieved
3 September 2018
Increased serum leptin protects from adiposity despite the increased glucose uptake in white adipose tissue in mice lacking p85alpha phosphoinositide 3-kinase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3756101
retrieved
3 September 2018
Enhanced T cell proliferation in mice lacking the p85beta subunit of phosphoinositide 3-kinase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3756101
retrieved
3 September 2018
Isoform-specific regulation of insulin-dependent glucose uptake by Akt/protein kinase B.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3756101
retrieved
3 September 2018
Reciprocal modulation of Toll-like receptor-4 signaling pathways involving MyD88 and phosphatidylinositol 3-kinase/AKT by saturated and polyunsaturated fatty acids
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3756101
retrieved
3 September 2018
Divergent regulation of hepatic glucose and lipid metabolism by phosphoinositide 3-kinase via Akt and PKCλ/ζ
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.4161%2FADIP.24645
retrieved
21 January 2018
Isoform-specific regulation of adipocyte differentiation by Akt/protein kinase Bα
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/23991359
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Insulin inhibits the expression of intercellular adhesion molecule-1 by human aortic endothelial cells through stimulation of nitric oxide
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/23991359
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.4161/ADIP.24645
1 reference
stated in
Europe PubMed Central
PMCID
3756101
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23991359%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 March 2020
PMCID
3756101
1 reference
stated in
Europe PubMed Central
PMCID
3756101
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23991359%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 March 2020
PubMed ID
23991359
1 reference
stated in
Europe PubMed Central
PMCID
3756101
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23991359%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 March 2020
ResearchGate publication ID
256291888
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