(Q37129268)

18 August 2017

1 reference

title

Insulin signalling in the heart (English)

1 reference

Jean-Louis Vanoverschelde

18 August 2017

1 reference

object named as

Jean-Louis Vanoverschelde

4

0 references

author name string

Luc Bertrand

1

1 reference

PubMed ID

18390897

18 August 2017

Sandrine Horman

2

1 reference

PubMed ID

18390897

18 August 2017

Christophe Beauloye

3

1 reference

18 August 2017

5 April 2008

1 reference

18 August 2017

Cardiovascular Research

1 reference

18 August 2017

79

1 reference

18 August 2017

2

1 reference

18 August 2017

238-248

1 reference

Actions of insulin on the mammalian heart: metabolism, pathology and biochemical mechanisms

18 August 2017

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVN093

Insulin-stimulated phosphorylation of a Rab GTPase-activating protein regulates GLUT4 translocation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVN093

Cardiac energy metabolism in obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVN093

Myocardial substrate metabolism in the normal and failing heart

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVN093

Metabolic and genetic regulation of cardiac energy substrate preference

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVN093

Energy metabolism in heart failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVN093

Distinct and overlapping functions of insulin and IGF-I receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVN093

Specificity in ligand binding and intracellular signalling by insulin and insulin-like growth factor receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVN093

Cardiovascular actions of insulin

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVN093

Insulin signal transduction through protein kinase cascades.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVN093

Insulin signalling and the regulation of glucose and lipid metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVN093

Tissue-specific roles of IRS proteins in insulin signaling and glucose transport

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVN093

Regulation of cardiac hypertrophy by intracellular signalling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVN093

Differences between pathological and physiological cardiac hypertrophy: novel therapeutic strategies to treat heart failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVN093

Ras, PI3-kinase and mTOR signaling in cardiac hypertrophy

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVN093

Mitogen-activated protein kinases in heart development and diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVN093

Phosphoinositide 3-kinases as a common platform for multi-hormone signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVN093

Deficiency of PDK1 in cardiac muscle results in heart failure and increased sensitivity to hypoxia

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVN093

Physiological roles of PKB/Akt isoforms in development and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVN093

Akt2 regulates cardiac metabolism and cardiomyocyte survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVN093

Role of the PDK1-PKB-GSK3 pathway in regulating glycogen synthase and glucose uptake in the heart

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVN093

Regulation of glucose transport, and glucose transporters expression and trafficking in the heart: studies in cardiac myocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVN093

Translocation of the glucose transporter GLUT4 in cardiac myocytes of the rat

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVN093

Bridging the GAP between insulin signaling and GLUT4 translocation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVN093

GLUT4 translocation: the last 200 nanometers

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVN093

The GLUT4 glucose transporter

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVN093

How many signals impinge on GLUT4 activation by insulin?

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVN093

AS160 regulates insulin- and contraction-stimulated glucose uptake in mouse skeletal muscle.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVN093

Substrate specificity and effect on GLUT4 translocation of the Rab GTPase-activating protein Tbc1d1

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVN093

Complementary regulation of TBC1D1 and AS160 by growth factors, insulin and AMPK activators

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVN093

Protein kinase B phosphorylation of PIKfyve regulates the trafficking of GLUT4 vesicles.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVN093

Akt2 phosphorylates Synip to regulate docking and fusion of GLUT4-containing vesicles

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVN093

Dissecting multiple steps of GLUT4 trafficking and identifying the sites of insulin action.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVN093

Atypical protein kinase C in insulin action and insulin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVN093

TC10alpha is required for insulin-stimulated glucose uptake in adipocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVN093

Activation of the Cbl insulin signaling pathway in cardiac muscle; dysregulation in obesity and diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVN093

Akt activity negatively regulates phosphorylation of AMP-activated protein kinase in the heart

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVN093

No-flow ischemia inhibits insulin signaling in heart by decreasing intracellular pH.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVN093

Insulin and ischemia stimulate glycolysis by acting on the same targets through different and opposing signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVN093

6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase: head-to-head with a bifunctional enzyme that controls glycolysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVN093

Heart 6-phosphofructo-2-kinase activation by insulin results from Ser-466 and Ser-483 phosphorylation and requires 3-phosphoinositide-dependent kinase-1, but not protein kinase B.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVN093

14-3-3s regulate fructose-2,6-bisphosphate levels by binding to PKB-phosphorylated cardiac fructose-2,6-bisphosphate kinase/phosphatase

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVN093

Cardiac expression of kinase-deficient 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase inhibits glycolysis, promotes hypertrophy, impairs myocyte function, and reduces insulin sensitivity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVN093

Cardiac substrate uptake and metabolism in obesity and type-2 diabetes: Role of sarcolemmal substrate transporters

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVN093

Regulation of sarcolemmal transport of substrates in the healthy and diseased heart.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVN093

Protein turnover in cardiac cell growth and survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVN093

Signalling to translation: how signal transduction pathways control the protein synthetic machinery

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVN093

Akt regulates growth by directly phosphorylating Tsc2

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVN093

TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVN093

Rheb fills a GAP between TSC and TOR.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVN093

Activation of protein synthesis in cardiomyocytes by the hypertrophic agent phenylephrine requires the activation of ERK and involves phosphorylation of tuberous sclerosis complex 2 (TSC2)

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVN093

Regulation of protein kinase B and 4E-BP1 by oxidative stress in cardiac myocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVN093

Glucose phosphorylation is required for insulin-dependent mTOR signalling in the heart

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVN093

Myocardial ischemia and increased heart work modulate the phosphorylation state of eukaryotic elongation factor-2

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVN093

Insulin signalling downstream of protein kinase B is potentiated by 5'AMP-activated protein kinase in rat hearts in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVN093

Myocardial protection by insulin at reperfusion requires early administration and is mediated via Akt and p70s6 kinase cell-survival signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVN093

The FOXO3a transcription factor regulates cardiac myocyte size downstream of AKT signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVN093

Activation of nitric oxide synthase in endothelial cells by Akt-dependent phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVN093

Insulin-stimulated activation of eNOS is independent of Ca2+ but requires phosphorylation by Akt at Ser(1179).

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVN093

Roles for insulin receptor, PI3-kinase, and Akt in insulin-signaling pathways related to production of nitric oxide in human vascular endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVN093

Molecular mechanisms involved in the regulation of the endothelial nitric oxide synthase

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVN093

Insulin-stimulated endothelial nitric oxide release is calcium independent and mediated via protein kinase B.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVN093

Akt1 regulates pathological angiogenesis, vascular maturation and permeability in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVN093

Synergistic activation of endothelial nitric-oxide synthase (eNOS) by HSP90 and Akt: calcium-independent eNOS activation involves formation of an HSP90-Akt-CaM-bound eNOS complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVN093

Insulin attenuation of vasoconstrictor responses to phenylephrine in Zucker lean and obese rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVN093

Insulin resistance in spontaneously hypertensive rats is associated with endothelial dysfunction characterized by imbalance between NO and ET-1 production.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVN093

Enhanced vascular activity of endogenous endothelin-1 in obese hypertensive patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVN093

Insulin stimulates glucose transport via nitric oxide/cyclic GMP pathway in human vascular smooth muscle cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVN093

Rho GTPases in cell biology

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVN093

Physiological role of ROCKs in the cardiovascular system

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVN093

AKT phosphorylation is essential for insulin-induced relaxation of rat vascular smooth muscle cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVN093

Nitric oxide induces dilation of rat aorta via inhibition of rho-kinase signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVN093

Role of AMP-activated protein kinase in healthy and diseased hearts

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVN093

AMPK alterations in cardiac physiology and pathology: enemy or ally?

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVN093

AMP-activated protein kinase in the heart: role during health and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVN093

AMP-activated protein kinase: a key stress signaling pathway in the heart

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVN093

AMP-Activated Protein Kinase in Metabolic Control and Insulin Signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVN093

Phosphorylation and activation of heart PFK-2 by AMPK has a role in the stimulation of glycolysis during ischaemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVN093

AMP-activated protein kinase suppresses protein synthesis in rat skeletal muscle through down-regulated mammalian target of rapamycin (mTOR) signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVN093

Thr2446 is a novel mammalian target of rapamycin (mTOR) phosphorylation site regulated by nutrient status

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVN093

Activation of AMP-activated protein kinase leads to the phosphorylation of elongation factor 2 and an inhibition of protein synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVN093

Activation of AMP-activated protein kinase inhibits protein synthesis associated with hypertrophy in the cardiac myocyte

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVN093

Expression of an active LKB1 complex in cardiac myocytes results in decreased protein synthesis associated with phenylephrine-induced hypertrophy

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVN093

Insulin antagonizes AMP-activated protein kinase activation by ischemia or anoxia in rat hearts, without affecting total adenine nucleotides.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVN093

Insulin antagonizes ischemia-induced Thr172 phosphorylation of AMP-activated protein kinase alpha-subunits in heart via hierarchical phosphorylation of Ser485/491.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVN093

Forty years of glucose-insulin-potassium (GIK) in cardiac surgery: a review of randomized, controlled trials

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVN093

Reperfusion injury salvage kinase signalling: taking a RISK for cardioprotection.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVN093

The benefits of glucose-insulin-potassium for acute myocardial infarction (and some concerns).

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVN093

Survival kinases in ischemic preconditioning and postconditioning.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVN093

New directions for protecting the heart against ischaemia-reperfusion injury: targeting the Reperfusion Injury Salvage Kinase (RISK)-pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVN093

Insulin-like growth factor I as a cardiac hormone: physiological and pathophysiological implications in heart disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVN093

IGF-I is a matter of heart

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVN093

Effect of glucose-insulin-potassium infusion on mortality in patients with acute ST-segment elevation myocardial infarction: the CREATE-ECLA randomized controlled trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVN093

A challenge to the metabolic approach to myocardial ischaemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVN093

Diabetic cardiomyopathy: the search for a unifying hypothesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVN093

Initial steps of insulin signaling and glucose transport are defective in the type 2 diabetic rat heart

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVN093

Cardiac dysfunction induced by high-fat diet is associated with altered myocardial insulin signalling in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVN093

Protein kinase B in the diabetic heart

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVN093

Targeting of PKCzeta and PKB to caveolin-enriched microdomains represents a crucial step underpinning the disruption in PKB-directed signalling by ceramide

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVN093

Mechanisms of insulin resistance in humans and possible links with inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVN093

Ser/Thr phosphorylation of IRS proteins: a molecular basis for insulin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVN093

Interaction of cardiovascular risk factors with myocardial ischemia/reperfusion injury, preconditioning, and postconditioning.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVN093

Diabetic cardiomyopathy revisited

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVN093

Activation of AMP-activated protein kinase in the liver: a new strategy for the management of metabolic hepatic disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVN093

AMPK activation restores the stimulation of glucose uptake in an in vitro model of insulin-resistant cardiomyocytes via the activation of protein kinase B.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVN093

Regulation of cardiac growth and coronary angiogenesis by the Akt/PKB signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVN093

Phosphoinositide 3-kinase(p110α) plays a critical role for the induction of physiological, but not pathological, cardiac hypertrophy

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVN093

Akt/protein kinase B promotes organ growth in transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVN093

Activation of AMP-activated protein kinase (AMPK) inhibits protein synthesis: a potential strategy to prevent the development of cardiac hypertrophy

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVN093

Hyperinsulinemia: effect on cardiac mass/function, angiotensin II receptor expression, and insulin signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVN093

Potential impact of carbohydrate and fat intake on pathological left ventricular hypertrophy

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVN093

Cardiac hypertrophy, substrate utilization and metabolic remodelling: cause or effect?

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVN093

Evaluation of the role of protein kinase Cζ in insulin-induced heart 6-phosphofructo-2-kinase activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVN093

Phosphorylation and Activation of Heart 6-Phosphofructo-2-kinase by Protein Kinase B and Other Protein Kinases of the Insulin Signaling Cascades

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVN093

Contraction-Induced Fatty Acid Translocase/CD36 Translocation in Rat Cardiac Myocytes Is Mediated Through AMP-Activated Protein Kinase Signaling

21 January 2018

1 reference

12 August 2022

https://opencitations.net/index/coci/api/v1/citations/10.2337/DIABETES.52.7.1627

Identifiers

DOI

10.1093/CVR/CVN093

1 reference

18 August 2017

1 reference

PubMed ID

18390897