(Q37165337)

English

An endogenous TNF-alpha antagonist induced by splice-switching oligonucleotides reduces inflammation in hepatitis and arthritis mouse models

scientific article published on 06 May 2008

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scholarly article

1 reference

Europe PubMed Central

18 August 2017

An endogenous TNF-alpha antagonist induced by splice-switching oligonucleotides reduces inflammation in hepatitis and arthritis mouse models (English)

1 reference

Europe PubMed Central

18 August 2017

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8

object named as

Ryszard Kole

1 reference

Europe PubMed Central

18 August 2017

author name string

Maria A Graziewicz

1

1 reference

Europe PubMed Central

18 August 2017

Teresa K Tarrant

2

1 reference

Europe PubMed Central

18 August 2017

Brian Buckley

3

1 reference

Europe PubMed Central

18 August 2017

Jennifer Roberts

4

1 reference

Europe PubMed Central

18 August 2017

LeShara Fulton

5

1 reference

Europe PubMed Central

18 August 2017

Henrik Hansen

6

1 reference

Europe PubMed Central

18 August 2017

Henrik Ørum

7

1 reference

Europe PubMed Central

18 August 2017

Peter Sazani

9

1 reference

Europe PubMed Central

18 August 2017

publication date

6 May 2008

1 reference

Europe PubMed Central

18 August 2017

Molecular Therapy

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Europe PubMed Central

18 August 2017

16

1 reference

Europe PubMed Central

18 August 2017

1316-1322

1 reference

Europe PubMed Central

18 August 2017

7

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Europe PubMed Central

18 August 2017

describes a project that uses

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2671678/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

LNA-mediated microRNA silencing in non-human primates

1 reference

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Correction of ClC-1 splicing eliminates chloride channelopathy and myotonia in mouse models of myotonic dystrophy

1 reference

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Antisense-mediated exon skipping: a versatile tool with therapeutic and research applications

1 reference

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6 September 2017

The versatility of oligonucleotides as potential therapeutics

1 reference

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Cell-penetrating peptide-morpholino conjugates alter pre-mRNA splicing of DMD (Duchenne muscular dystrophy) and inhibit murine coronavirus replication in vivo.

1 reference

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1 reference

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Antisense oligonucleotide-induced alternative splicing of the APOB mRNA generates a novel isoform of APOB.

1 reference

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Seppo Santavirta, 1945-2005.

1 reference

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New drugs for rheumatoid arthritis

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Identification and functional validation of PNAs that inhibit murine CD40 expression by redirection of splicing

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Anti-TNF-alpha therapies: the next generation

1 reference

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Effect of hepatocyte apoptosis induced by TNF-alpha on acute severe hepatitis in mouse models

1 reference

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Correction of alternative splicing of tau in frontotemporal dementia and parkinsonism linked to chromosome 17.

1 reference

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Combination therapy with multiple disease-modifying antirheumatic drugs in rheumatoid arthritis: a preventive strategy

1 reference

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Induction of tumour necrosis factor (TNF) receptor type p55 and p75 in patients with chronic hepatitis C virus (HCV) infection

1 reference

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In vivo tumor growth inhibition and biodistribution studies of locked nucleic acid (LNA) antisense oligonucleotides

1 reference

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Modification of MyD88 mRNA splicing and inhibition of IL-1beta signaling in cell culture and in mice with a 2'-O-methoxyethyl-modified oligonucleotide

1 reference

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Repair of a splicing defect in erythroid cells from patients with beta-thalassemia/HbE disorder

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Antisense oligonucleotides containing locked nucleic acid improve potency but cause significant hepatotoxicity in animals

1 reference

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27 June 2018

Systemically delivered antisense oligomers upregulate gene expression in mouse tissues

1 reference

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Oral delivery of antisense oligonucleotides in man.

1 reference

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3 September 2018

Potent reduction of apolipoprotein B and low-density lipoprotein cholesterol by short-term administration of an antisense inhibitor of apolipoprotein B.

1 reference

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Systemic delivery of morpholino oligonucleotide restores dystrophin expression bodywide and improves dystrophic pathology

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Identification and characterization of a novel spliced variant that encodes human soluble tumor necrosis factor receptor 2.

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Functional amounts of dystrophin produced by skipping the mutated exon in the mdx dystrophic mouse

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Correction of disease-associated exon skipping by synthetic exon-specific activators

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Characterization of different soluble TNF receptor (TNFR80) derivatives: positive influence of the intracellular domain on receptor/ligand interaction and TNF neutralization capacity.

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Treatment of rheumatoid arthritis

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Sensitization and desensitization to lethal effects of tumor necrosis factor and IL-1

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The trapping of uridine phosphates by D-galactosamine. D-glucosamine, and 2-deoxy-D-galactose. A study on the mechanism of galactosamine hepatitis

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Influence of a recombinant human soluble tumor necrosis factor receptor FC fusion protein on type II collagen-induced arthritis in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/18461057

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Serum levels and in situ expression of TNF-alpha and TNF-alpha binding proteins in inflammatory liver diseases

1 reference

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Diagnosis and management of rheumatoid arthritis

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Current management: Management of rheumatic diseases in the era of biological anti-rheumatic drugs

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Analysis of prostate-specific membrane antigen splice variants in LNCap cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/18461057

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Efficient and persistent splice switching by systemically delivered LNA oligonucleotides in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/18461057

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Neutralization of tumor necrosis factor (TNF) by antibody but not TNF receptor fusion molecule exacerbates chronic murine tuberculosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/18461057

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Collagen-induced arthritis

1 reference

https://pubmed.ncbi.nlm.nih.gov/18461057

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based on heuristic

inferred from PubMed ID database lookup

Local dystrophin restoration with antisense oligonucleotide PRO051

1 reference

https://pubmed.ncbi.nlm.nih.gov/18461057

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1038/MT.2008.85

1 reference

Europe PubMed Central

18 August 2017

1 reference

Europe PubMed Central

18 August 2017

1 reference

Europe PubMed Central

18 August 2017

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