(Q37168903)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23843627%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

title

Two distinct functions for PI3-kinases in macropinocytosis (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23843627%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

1 reference

6

1 reference

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5 March 2020

Robert R. Kay

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23843627%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

author name string

Oliver Hoeller

1

1 reference

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5 March 2020

Parvin Bolourani

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23843627%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

Jonathan Clark

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23843627%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

Len R Stephens

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23843627%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

Phillip T Hawkins

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23843627%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

Gerald Weeks

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23843627%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

language of work or name

English

0 references

publication date

10 July 2013

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23843627%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

published in

Journal of Cell Science

1 reference

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5 March 2020

volume

126

1 reference

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5 March 2020

issue

Pt 18

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23843627%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

page(s)

4296-4307

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23843627%20AND%20SRC:MED&resulttype=core&format=json

describes a project that uses

5 March 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3772393/fullTextXML

inferred from PubMed Central ID database lookup

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6 September 2017

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G protein-independent Ras/PI3K/F-actin circuit regulates basic cell motility

6 September 2017

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Delineation of the roles played by RasG and RasC in cAMP-dependent signal transduction during the early development of Dictyostelium discoideum

6 September 2017

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Distinct roles of PI(3,4,5)P3 during chemoattractant signaling in Dictyostelium: a quantitative in vivo analysis by inhibition of PI3-kinase

6 September 2017

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6 September 2017

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A novel phosphatidylinositol(3,4,5)P3 pathway in fission yeast

6 September 2017

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Chemoattractant-induced phosphatidylinositol 3,4,5-trisphosphate accumulation is spatially amplified and adapts, independent of the actin cytoskeleton

6 September 2017

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Regulation of cell polarity during eukaryotic chemotaxis: the chemotactic compass

6 September 2017

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Sequential activities of phosphoinositide 3-kinase, PKB/Aakt, and Rab7 during macropinosome formation in Dictyostelium

6 September 2017

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Restricted accumulation of phosphatidylinositol 3-kinase products in a plasmalemmal subdomain during Fc gamma receptor-mediated phagocytosis

6 September 2017

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Synthesis and function of 3-phosphorylated inositol lipids

6 September 2017

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Phagocytosis and macropinocytosis in Dictyostelium: phosphoinositide-based processes, biochemically distinct

6 September 2017

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6 September 2017

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Crystal structure and functional analysis of Ras binding to its effector phosphoinositide 3-kinase gamma

6 September 2017

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Localized biphasic changes in phosphatidylinositol-4,5-bisphosphate at sites of phagocytosis

6 September 2017

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6 September 2017

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Use of a fusion protein between GFP and an actin-binding domain to visualize transient filamentous-actin structures

6 September 2017

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Inactivation of two Dictyostelium discoideum genes, DdPIK1 and DdPIK2, encoding proteins related to mammalian phosphatidylinositide 3-kinases, results in defects in endocytosis, lysosome to postlysosome transport, and actin cytoskeleton organization

6 September 2017

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A role for phosphoinositide 3-kinase in the completion of macropinocytosis and phagocytosis by macrophages

6 September 2017

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Activation of phosphoinositide 3-kinase by interaction with Ras and by point mutation

6 September 2017

1 reference

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Phosphatidylinositol-3-OH kinase as a direct target of Ras

6 September 2017

1 reference

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Dictyostelium chemotaxis: essential Ras activation and accessory signalling pathways for amplification

6 September 2017

1 reference

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Receptor-like tyrosine phosphatases CD45 and CD148 have distinct functions in chemoattractant-mediated neutrophil migration and response to S. aureus

14 September 2017

1 reference

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Self-organizing actin waves that simulate phagocytic cup structures

14 September 2017

1 reference

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Phosphoinositide metabolism during membrane ruffling and macropinosome formation in EGF-stimulated A431 cells

14 September 2017

1 reference

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Role of phosphatidylinositol 3-kinases in chemotaxis in Dictyostelium

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3772393

Exploring the specificity of the PI3K family inhibitor LY294002.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3772393

Receptor activation alters inner surface potential during phagocytosis

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3772393

Temporal and spatial regulation of phosphoinositide signaling mediates cytokinesis

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3772393

Chemoattractant-induced Ras activation during Dictyostelium aggregation

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3772393

A phosphatidylinositol (PI) kinase gene family in Dictyostelium discoideum: biological roles of putative mammalian p110 and yeast Vps34p PI 3-kinase homologs during growth and development

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3772393

Signaling specificity by Ras family GTPases is determined by the full spectrum of effectors they regulate

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3772393

Activation of phosphoinositide 3-kinase gamma by Ras.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3772393

A requirement for phosphatidylinositol 3-kinase in pseudopod extension

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3772393

PI 3-kinase is a dual specificity enzyme: autoregulation by an intrinsic protein-serine kinase activity.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3772393

PLA2 and PI3K/PTEN pathways act in parallel to mediate chemotaxis

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3772393

Localized Ras signaling at the leading edge regulates PI3K, cell polarity, and directional cell movement

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3772393

Role of phosphatidylinositol 3' kinase and a downstream pleckstrin homology domain-containing protein in controlling chemotaxis in dictyostelium

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3772393

Dictyostelium RasG is required for normal motility and cytokinesis, but not growth.

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3772393

Circular ruffle formation and closure lead to macropinocytosis in hepatocyte growth factor/scatter factor-treated cells

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3772393

Activation of phosphoinositide 3-kinase is required for PDGF-stimulated membrane ruffling

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3772393

The morphologic pathway of binding and internalization of epidermal growth factor in cultured cells. Studies on A431, KB, and 3T3 cells, using multiple methods of labelling

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3772393

Growth of myxamoebae of the cellular slime mould Dictyostelium discoideum in axenic culture

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3772393

Disruption of the Dictyostelium myosin heavy chain gene by homologous recombination.

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3772393

Phosphoinositides differentially regulate bacterial uptake and Nramp1-induced resistance to Legionella infection in Dictyostelium.

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3772393

PI3-kinase signaling contributes to orientation in shallow gradients and enhances speed in steep chemoattractant gradients.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3772393

The effect of the disruption of a gene encoding a PI4 kinase on the developmental defect exhibited by Dictyostelium rasC(-) cells

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3772393

In vivo analysis of 3-phosphoinositide dynamics during Dictyostelium phagocytosis and chemotaxis.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3772393

A brilliant monomeric red fluorescent protein to visualize cytoskeleton dynamics in Dictyostelium.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3772393

A Lim protein involved in the progression of cytokinesis and regulation of the mitotic spindle

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3772393

Spatial and temporal regulation of 3-phosphoinositides by PI 3-kinase and PTEN mediates chemotaxis

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3772393

Tumor suppressor PTEN mediates sensing of chemoattractant gradients.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3772393

Disruption of Dictyostelium PI3K genes reduces [32P]phosphatidylinositol 3,4 bisphosphate and [32P]phosphatidylinositol trisphosphate levels, alters F-actin distribution and impairs pinocytosis.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3772393

Possible roles of the endocytic cycle in cell motility

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3772393

Chemotaxis in the Absence of PIP3 Gradients

4 December 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3772393

PI(3)Kγ has an important context-dependent role in neutrophil chemokinesis

4 December 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3772393

PI3Kγ Modulates the Cardiac Response to Chronic Pressure Overload by Distinct Kinase-Dependent and -Independent Effects

4 December 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3772393

Bifurcation of lipid and protein kinase signals of PI3Kgamma to the protein kinases PKB and MAPK

4 December 2018

1 reference

12 December 2020

Visualization of actin dynamics during macropinocytosis and exocytosis

1 reference

12 December 2020

The Dictyostelium RasS protein is required for macropinocytosis, phagocytosis and the control of cell movement

1 reference

12 December 2020

Cell motility and SCAR localisation in axenically growing Dictyostelium cells

1 reference

12 December 2020

G protein signaling events are activated at the leading edge of chemotactic cells

1 reference

12 December 2020

Uncoupling of membrane ruffling and pinocytosis during Ras signal transduction

1 reference

12 December 2020

Coronin involved in phagocytosis: dynamics of particle-induced relocalization visualized by a green fluorescent protein Tag

1 reference

12 December 2020

Induction of membrane ruffling and fluid-phase pinocytosis in quiescent fibroblasts by ras proteins

1 reference

12 December 2020

Identifiers

DOI

10.1242/JCS.134015

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23843627%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23843627%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

PubMed publication ID

23843627

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23843627%20AND%20SRC:MED&resulttype=core&format=json