(Q37173076)

18 August 2017

Structural characterization of the interaction of α-synuclein nascent chains with the ribosomal surface and trigger factor (English)

1 reference

18 August 2017

1 reference

10

Christopher M Dobson

1 reference

18 August 2017

11

Michele Vendruscolo

1 reference

18 August 2017

Annika Deckert

1

0 references

Christopher A Waudby

object named as

Christopher A Waudby

2

0 references

Carlo Camilloni

object named as

Carlo Camilloni

8

0 references

author name string

Tomasz Wlodarski

3

1 reference

18 August 2017

Anne S Wentink

4

1 reference

18 August 2017

Xiaolin Wang

5

1 reference

18 August 2017

John P Kirkpatrick

6

1 reference

18 August 2017

Jack F S Paton

7

1 reference

18 August 2017

Predrag Kukic

9

1 reference

18 August 2017

Lisa D Cabrita

12

1 reference

18 August 2017

John Christodoulou

13

1 reference

18 August 2017

language of work or name

English

0 references

publication date

18 April 2016

1 reference

Proceedings of the National Academy of Sciences of the United States of America

18 August 2017

1 reference

18 August 2017

113

1 reference

18 August 2017

18

1 reference

18 August 2017

5012-5017

1 reference

A structural ensemble of a ribosome-nascent chain complex during cotranslational protein folding

18 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4983817

Structural disorder of monomeric α-synuclein persists in mammalian cells.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4983817

Folding of an intrinsically disordered protein by phosphorylation as a regulatory switch

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4983817

The power of coarse graining in biomolecular simulations.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4983817

Structural Basis for Protein Antiaggregation Activity of the Trigger Factor Chaperone

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4983817

In-cell NMR characterization of the secondary structure populations of a disordered conformation of α-synuclein within E. coli cells

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4983817

The remarkable conformational plasticity of alpha-synuclein: blessing or curse?

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4983817

GROMACS 4.5: a high-throughput and highly parallel open source molecular simulation toolkit

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4983817

In vivo translation rates can substantially delay the cotranslational folding of the Escherichia coli cytosolic proteome

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4983817

Mechanisms of SecM-mediated stalling in the ribosome

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4983817

Ribosome-associated chaperones as key players in proteostasis

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4983817

Residue-specific α-helix propensities from molecular simulation

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4983817

SecM-stalled ribosomes adopt an altered geometry at the peptidyl transferase center

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4983817

Protein folding in the cell: challenges and progress

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4983817

Folding at the birth of the nascent chain: coordinating translation with co-translational folding

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4983817

Cotranslational structure acquisition of nascent polypeptides monitored by NMR spectroscopy

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4983817

Probing ribosome-nascent chain complexes produced in vivo by NMR spectroscopy

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4983817

The native 3D organization of bacterial polysomes

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4983817

Proteins with weakly funneled energy landscapes challenge the classical structure-function paradigm

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4983817

Molecular mechanism and structure of Trigger Factor bound to the translating ribosome

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4983817

Differential dynamical effects of macromolecular crowding on an intrinsically disordered protein and a globular protein: implications for in-cell NMR spectroscopy

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4983817

Structure and dynamics of a ribosome-bound nascent chain by NMR spectroscopy

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4983817

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4983817

Molecular simulations of cotranslational protein folding: fragment stabilities, folding cooperativity, and trapping in the ribosome

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4983817

Heteronuclear NMR investigations of dynamic regions of intact Escherichia coli ribosomes

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4983817

Protein folding and misfolding

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4983817

Slow diffusion of macromolecular assemblies by a new pulsed field gradient NMR method

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4983817

Binding specificity of Escherichia coli trigger factor

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4983817

Secretion monitor, SecM, undergoes self-translation arrest in the cytosol

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4983817

mRNA composition and control of bacterial gene expression

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4983817

Pair potentials for protein folding: choice of reference states and sensitivity of predicted native states to variations in the interaction schemes

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4983817

Study of Escherichia coli ribosomes by intensity fluctuation spectroscopy of scattered laser light

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4983817

Rotational diffusion of Escherichia coli ribosomes. I. - Free 70 S, 50 S and 30 S particles

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4983817

The ribosome modulates nascent protein folding

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4983817

Versatility of trigger factor interactions with ribosome-nascent chain complexes

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4983817

Confined dynamics of a ribosome-bound nascent globin: Cone angle analysis of fluorescence depolarization decays in the presence of two local motions

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4983817

Practical protocols for production of very high yields of recombinant proteins using Escherichia coli

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4983817

Fluorescence-based analysis of aminoacyl- and peptidyl-tRNA by low-pH sodium dodecyl sulfate-polyacrylamide gel electrophoresis

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4983817

Co-translational domain folding as the structural basis for the rapid de novo folding of firefly luciferase

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4983817

A relationship between the aggregation rates of α-synuclein variants and the β-sheet populations in their monomeric forms

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4983817

Reshaping of the conformational search of a protein by the chaperone trigger factor.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4983817

Dynamic enzyme docking to the ribosome coordinates N-terminal processing with polypeptide folding.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4983817

Electrostatic effect of the ribosomal surface on nascent polypeptide dynamics

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4983817

Trigger factor slows co-translational folding through kinetic trapping while sterically protecting the nascent chain from aberrant cytosolic interactions.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4983817

An analysis of NMR sensitivity enhancements obtained using non-uniform weighted sampling, and the application to protein NMR.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4983817

alpha-Helical nascent polypeptide chains visualized within distinct regions of the ribosomal exit tunnel

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4983817

Large-scale purification of ribosome-nascent chain complexes for biochemical and structural studies.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4983817

Real-time observation of trigger factor function on translating ribosomes.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4983817

Trigger factor binding to ribosomes with nascent peptide chains of varying lengths and sequences.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4983817

Trigger factor in complex with the ribosome forms a molecular cradle for nascent proteins.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4983817

Three-state equilibrium of Escherichia coli trigger factor

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4983817

L23 protein functions as a chaperone docking site on the ribosome

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4983817

Mapping Long-Range Interactions in α-Synuclein using Spin-Label NMR and Ensemble Molecular Dynamics Simulations

3 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.1519124113

Very Fast Two-Dimensional NMR Spectroscopy for Real-Time Investigation of Dynamic Events in Proteins on the Time Scale of Seconds

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.1519124113

A Multifaceted Approach to the Interpretation of NMR Order Parameters: A Case Study of a Dynamic α-Helix†

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.1519124113

Exploring the capacity of trigger factor to function as a shield for ribosome bound polypeptide chains

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27092002

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Concerted action of the ribosome and the associated chaperone trigger factor confines nascent polypeptide folding

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27092002

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Secondary structure formation of a transmembrane segment in Kv channels

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27092002

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.1519124113

1 reference

18 August 2017

0 references

1 reference

18 August 2017

PubMed publication ID

27092002

1 reference