(Q37175533)

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Serine proteases

scientific article published on May 2009

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scholarly article

1 reference

Europe PubMed Central

18 August 2017

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Europe PubMed Central

Serine proteases. (English)

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Europe PubMed Central

18 August 2017

author name string

Enrico Di Cera

1

1 reference

Europe PubMed Central

18 August 2017

publication date

1 May 2009

1 reference

Europe PubMed Central

18 August 2017

1 reference

Europe PubMed Central

18 August 2017

61

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Europe PubMed Central

18 August 2017

5

1 reference

Europe PubMed Central

18 August 2017

510-515

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Europe PubMed Central

18 August 2017

Conformational changes in an ultrafast light-driven enzyme determine catalytic activity

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Testing Geometrical Discrimination within an Enzyme Active Site: Constrained Hydrogen Bonding in the Ketosteroid Isomerase Oxyanion Hole

1 reference

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Evolution of peptidase diversity

1 reference

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Allosteric regulation and catalysis emerge via a common route.

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Highly active and selective endopeptidases with programmed substrate specificities

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6 September 2017

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Serine peptidases: classification, structure and function

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Structural identification of the pathway of long-range communication in an allosteric enzyme

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The type II transmembrane serine protease matriptase-2--identification, structural features, enzymology, expression pattern and potential roles

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Human pancreatic digestive enzymes

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Structure-function properties of prolyl oligopeptidase family enzymes

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A structural perspective on enzymes activated by monovalent cations

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Allosteric mechanisms of signal transduction

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A genomic view of the complexity of mammalian proteolytic systems.

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Conformational lability in serine protease active sites: structures of hepatocyte growth factor activator (HGFA) alone and with the inhibitory domain from HGFA inhibitor-1B

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Structural analysis of engineered Bb fragment of complement factor B: insights into the activation mechanism of the alternative pathway C3-convertase

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Ala226 to Gly and Ser189 to Asp mutations convert rat chymotrypsin B to a trypsin-like protease

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Staphylocoagulase is a prototype for the mechanism of cofactor-induced zymogen activation

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ON THE NATURE OF ALLOSTERIC TRANSITIONS: A PLAUSIBLE MODEL

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The reaction of p-nitrophenyl esters with chymotrypsin and insulin

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Membrane anchored serine proteases: a rapidly expanding group of cell surface proteolytic enzymes with potential roles in cancer

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Structural aspects of the metzincin clan of metalloendopeptidases.

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6 September 2017

Structure of human pro-chymase: a model for the activating transition of granule-associated proteases

1 reference

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6 September 2017

Serine protease mechanism and specificity

1 reference

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6 September 2017

The 2.2-A crystal structure of human pro-granzyme K reveals a rigid zymogen with unusual features

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Crystal structure of a prostate kallikrein isolated from stallion seminal plasma: a homologue of human PSA

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Structure of arterivirus nsp4. The smallest chymotrypsin-like proteinase with an alpha/beta C-terminal extension and alternate conformations of the oxyanion hole

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Cytotoxic T lymphocytes: all roads lead to death

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6 September 2017

Crystal structure of DegP (HtrA) reveals a new protease-chaperone machine

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6 September 2017

Enzyme dynamics during catalysis

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The new human kallikrein gene family: implications in carcinogenesis

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6 September 2017

Molecular cloning of cDNA for matriptase, a matrix-degrading serine protease with trypsin-like activity

1 reference

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6 September 2017

Single-molecule enzymatic dynamics

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Structures of native and complexed complement factor D: implications of the atypical His57 conformation and self-inhibitory loop in the regulation of specific serine protease activity

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6 September 2017

Human beta-tryptase is a ring-like tetramer with active sites facing a central pore

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The crystal structure of the asymmetric GroEL-GroES-(ADP)7 chaperonin complex

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Structural basis of substrate specificity in the serine proteases

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On the size of the active site in proteases. I. Papain

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Role of a Buried Acid Group in the Mechanism of Action of Chymotrypsin

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Bovine chymotrypsinogen A X-ray crystal structure analysis and refinement of a new crystal form at 1.8 A resolution

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Crystal structure of bovine trypsinogen at 1-8 A resolution. II. Crystallographic refinement, refined crystal structure and comparison with bovine trypsin

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Kinin formation: mechanisms and role in inflammatory disorders

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Trypsin: a case study in the structural determinants of enzyme specificity

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X-ray structures of free and leupeptin-complexed human alphaI-tryptase mutants: indication for an alpha-->beta-tryptase transition

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Agonists of proteinase-activated receptor 2 induce inflammation by a neurogenic mechanism

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27 June 2018

Conversion of thrombin into an anticoagulant by protein engineering

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27 June 2018

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27 June 2018

Engineering protease specificity made simple, but not simpler

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3 September 2018

Energetic and structural consequences of perturbing Gly-193 in the oxyanion hole of serine proteases

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3 September 2018

Molecular dissection of Na+ binding to thrombin.

1 reference

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3 September 2018

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3 September 2018

Lysine 156 promotes the anomalous proenzyme activity of tPA: X-ray crystal structure of single-chain human tPA.

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3 September 2018

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1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rapid kinetics of Na+ binding to thrombin

1 reference

https://pubmed.ncbi.nlm.nih.gov/19180666

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

MEROPS: the peptidase database

1 reference

https://pubmed.ncbi.nlm.nih.gov/19180666

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Converting trypsin to elastase: substitution of the S1 site and adjacent loops reconstitutes esterase specificity but not amidase activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/19180666

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rational design of a potent anticoagulant thrombin

1 reference

https://pubmed.ncbi.nlm.nih.gov/19180666

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structure and activation of trypsinogen and chymotrypsinogen

1 reference

https://pubmed.ncbi.nlm.nih.gov/19180666

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Enzymes under the nanoscope

1 reference

https://pubmed.ncbi.nlm.nih.gov/19180666

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Anticoagulant Thrombin Mutant W215A/E217A Has a Collapsed Primary Specificity Pocket

1 reference

https://pubmed.ncbi.nlm.nih.gov/19180666

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Kinetic aspects of regulation of metabolic processes. The hysteretic enzyme concept

1 reference

https://pubmed.ncbi.nlm.nih.gov/19180666

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stereochemistry of Cooperative Effects in Haemoglobin: Haem–Haem Interaction and the Problem of Allostery

1 reference

https://pubmed.ncbi.nlm.nih.gov/19180666

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Equilibrium and rate constants for the interconversion of two conformations of -chymotrypsin. The existence of a catalytically inactive conformation at neutral p H

1 reference

https://pubmed.ncbi.nlm.nih.gov/19180666

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Conformational equilibria in -and -chymotrypsin. The energetics and importance of the salt bridge

1 reference

https://pubmed.ncbi.nlm.nih.gov/19180666

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transients and cooperativity. A slow transition model for relating transients and cooperative kinetics of enzymes

1 reference

https://pubmed.ncbi.nlm.nih.gov/19180666

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1002/IUB.186

1 reference

Europe PubMed Central

18 August 2017

1 reference

Europe PubMed Central

18 August 2017

1 reference

Europe PubMed Central

18 August 2017

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