(Q37179317)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26450454%20AND%20SRC:MED&resulttype=core&format=json

26 February 2020

title

Conditional knockdown of BCL2A1 reveals rate-limiting roles in BCR-dependent B-cell survival (English)

1 reference

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26 February 2020

1

1 reference

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26 February 2020

Eleonora Ottina

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26450454%20AND%20SRC:MED&resulttype=core&format=json

26 February 2020

Selma Tuzlak

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26450454%20AND%20SRC:MED&resulttype=core&format=json

26 February 2020

Sebastian Herzog

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26450454%20AND%20SRC:MED&resulttype=core&format=json

26 February 2020

Marco J Herold

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26450454%20AND%20SRC:MED&resulttype=core&format=json

26 February 2020

author name string

A Villunger

6

1 reference

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26 February 2020

publication date

9 October 2015

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26450454%20AND%20SRC:MED&resulttype=core&format=json

Cell Death & Differentiation

26 February 2020

published in

1 reference

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26 February 2020

volume

23

1 reference

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26 February 2020

issue

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26450454%20AND%20SRC:MED&resulttype=core&format=json

26 February 2020

page(s)

628-639

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26450454%20AND%20SRC:MED&resulttype=core&format=json

Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International

26 February 2020

copyright license

start time

9 October 2015

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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Pax5 loss imposes a reversible differentiation block in B-progenitor acute lymphoblastic leukemia

6 September 2017

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IFN-γ regulates survival and function of tumor-induced CD11b+ Gr-1high myeloid derived suppressor cells by modulating the anti-apoptotic molecule Bcl2a1.

6 September 2017

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MLL3 is a haploinsufficient 7q tumor suppressor in acute myeloid leukemia

6 September 2017

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Conditional reverse tet-transactivator mouse strains for the efficient induction of TRE-regulated transgenes in mice

6 September 2017

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Control of apoptosis by the BCL-2 protein family: implications for physiology and therapy.

6 September 2017

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Mitochondrial regulation of cell death.

6 September 2017

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Variability of inducible expression across the hematopoietic system of tetracycline transactivator transgenic mice.

6 September 2017

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Anti-apoptotic BFL-1 is the major effector in activation-induced human mast cell survival

6 September 2017

1 reference

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Targeting antiapoptotic A1/Bfl-1 by in vivo RNAi reveals multiple roles in leukocyte development in mice

6 September 2017

1 reference

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A1/Bfl-1 in leukocyte development and cell death

6 September 2017

1 reference

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BCL2A1: the underdog in the BCL2 family

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4986635

A rapid and scalable system for studying gene function in mice using conditional RNA interference

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4986635

Regulation of B-cell proliferation and differentiation by pre-B-cell receptor signalling

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4986635

Life and death during hematopoietic differentiation

6 September 2017

1 reference

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Nur77 converts phenotype of Bcl-B, an antiapoptotic protein expressed in plasma cells and myeloma

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4986635

Efficiency of RNA interference in the mouse hematopoietic system varies between cell types and developmental stages

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4986635

Polycystic kidney disease prevented by transgenic RNA interference

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4986635

The BCL2A1 gene as a pre-T cell receptor-induced regulator of thymocyte survival

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4986635

p53- and drug-induced apoptotic responses mediated by BH3-only proteins puma and noxa

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4986635

Phospholipase Cgamma2 provides survival signals via Bcl2 and A1 in different subpopulations of B cells

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4986635

Bad-deficient mice develop diffuse large B cell lymphoma

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4986635

Positive and negative selection during B lymphocyte development

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4986635

Essential role of the prosurvival bcl-2 homologue A1 in mast cell survival after allergic activation

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4986635

Interference with immunoglobulin (Ig)alpha immunoreceptor tyrosine-based activation motif (ITAM) phosphorylation modulates or blocks B cell development, depending on the availability of an Igbeta cytoplasmic tail

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4986635

Mice transgenic for BAFF develop lymphocytic disorders along with autoimmune manifestations

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4986635

Proapoptotic Bcl-2 relative Bim required for certain apoptotic responses, leukocyte homeostasis, and to preclude autoimmunity

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4986635

Multiple gene duplication and expression of mouse bcl-2-related genes, A1.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4986635

B lymphocytes differentially use the Rel and nuclear factor kappaB1 (NF-kappaB1) transcription factors to regulate cell cycle progression and apoptosis in quiescent and mitogen-activated cells

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4986635

Bcl-2-deficient mice demonstrate fulminant lymphoid apoptosis, polycystic kidneys, and hypopigmented hair

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4986635

Disappearance of the lymphoid system in Bcl-2 homozygous mutant chimeric mice

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4986635

Characterization of A1, a novel hemopoietic-specific early-response gene with sequence similarity to bcl-2

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4986635

Developmental regulation of the Bcl-2 protein and susceptibility to cell death in B lymphocytes

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4986635

Bcl-XL displays restricted distribution during T cell development and inhibits multiple forms of apoptosis but not clonal deletion in transgenic mice

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4986635

Altered immunoglobulin expression and functional silencing of self-reactive B lymphocytes in transgenic mice.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4986635

Knockdown of the antiapoptotic Bcl-2 family member A1/Bfl-1 protects mice from anaphylaxis

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4986635

Long-lived B cells are distinguished by elevated expression of A1.

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4986635

Characterisation of a novel A1-specific monoclonal antibody.

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4986635

Concurrent up-regulation of BCL-XL and BCL2A1 induces approximately 1000-fold resistance to ABT-737 in chronic lymphocytic leukemia

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4986635

The anti-apoptotic Bcl-2 family member Mcl-1 promotes T lymphocyte survival at multiple stages

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4986635

Vav promoter-tTA conditional transgene expression system for hematopoietic cells drives high level expression in developing B and T cells.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4986635

The stability and anti-apoptotic function of A1 are controlled by its C terminus.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4986635

Regulation of A1/Bfl-1 expression in peripheral splenic B cells

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4986635

4-1BB promotes the survival of CD8+ T lymphocytes by increasing expression of Bcl-xL and Bfl-1.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4986635

Accelerated neutrophil apoptosis in mice lacking A1-a, a subtype of the bcl-2-related A1 gene.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4986635

Bcmd governs recruitment of new B cells into the stable peripheral B cell pool in the A/WySnJ mouse.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4986635

An Essential Role for BAFF in the Normal Development of B Cells Through a BCMA-Independent Pathway

3 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FCDD.2015.130

A1/Bfl-1 expression is restricted to TCR engagement in T lymphocytes

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FCDD.2015.130

A1 is a growth-permissive antiapoptotic factor mediating postactivation survival in T cells

21 January 2018

1 reference

12 December 2020

A1 is a constitutive and inducible Bcl-2 homologue in mature human neutrophils

1 reference

12 December 2020

Contribution of BCAP to maintenance of mature B cells through c-Rel

1 reference

12 December 2020

A1 expression is stimulated by CD40 in B cells and rescues WEHI 231 cells from anti-IgM-induced cell death

1 reference

12 December 2020

Identifiers

DOI

10.1038/CDD.2015.130

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26450454%20AND%20SRC:MED&resulttype=core&format=json

26 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26450454%20AND%20SRC:MED&resulttype=core&format=json

26 February 2020

PubMed publication ID

26450454

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26450454%20AND%20SRC:MED&resulttype=core&format=json