(Q37182845)

18 August 2017

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title

On the key role played by altered protein conformation in Parkinson's disease (English)

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18 August 2017

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V Vellani

5

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Daniel Marcellino

D Marcellino

6

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Diego Guidolin

D Guidolin

7

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Kjell Fuxe

K Fuxe

8

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Luigi Francesco Agnati

1

Agnati LF

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18 August 2017

2

Baldelli E

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18 August 2017

3

Andreoli N

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18 August 2017

4

Woods AS

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18 August 2017

language of work or name

English

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publication date

5 June 2008

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Journal of Neural Transmission

18 August 2017

published in

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18 August 2017

volume

115

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18 August 2017

issue

9

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18 August 2017

page(s)

1285-1299

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https://scigraph.springernature.com/pub.10.1007/s00702-008-0072-1

18 August 2017

exact match

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cites work

Oligomerizaiton and fibril asssembly of the amyloid-beta protein.

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Crossref

https://api.crossref.org/works/10.1007%2FS00702-008-0072-1

A critical review of the development and importance of proteinaceous aggregates in animal models of Parkinson's disease: new insights into Lewy body formation

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Agrin binds alpha-synuclein and modulates alpha-synuclein fibrillation.

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Generation of aggregated beta-amyloid in the rat hippocampus impairs synaptic transmission and plasticity and causes memory deficits

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Amyloid-beta in Alzheimer's disease: the horse or the cart? Pathogenic or protective?

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Phosphorylation at Ser-129 but not the phosphomimics S129E/D inhibits the fibrillation of alpha-synuclein.

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12 December 2020

Structural plasticity in G-protein coupled receptors as demonstrated by the allosteric actions of homocysteine and computer-assisted analysis of disordered domains.

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12 December 2020

Protein folding and misfolding

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Glycosaminoglycans and beta-amyloid, prion and tau peptides in neurodegenerative diseases

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12 December 2020

Kinetic stabilization of the alpha-synuclein protofibril by a dopamine-alpha-synuclein adduct

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12 December 2020

Glial reaction in aging and Alzheimer's disease

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12 December 2020

Diffusible, nonfibrillar ligands derived from Abeta1-42 are potent central nervous system neurotoxins

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12 December 2020

Origins and effects of extracellular alpha-synuclein: implications in Parkinson's disease

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12 December 2020

Protein disorder prediction: implications for structural proteomics

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12 December 2020

Genetic factors involved in the pathogenesis of Parkinson's disease.

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12 December 2020

Neuronal death: where does the end begin?

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12 December 2020

Reduced amino acid alphabet is sufficient to accurately recognize intrinsically disordered protein.

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12 December 2020

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12 December 2020

Heterozygosity for a Mendelian disorder as a risk factor for complex disease

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12 December 2020

Oxidative stress and aberrant signaling in aging and cognitive decline

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12 December 2020

Alpha-synuclein and Parkinson's disease

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12 December 2020

Cell systems and the toxic mechanism(s) of alpha-synuclein

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12 December 2020

Further analysis of nucleic acids in purified scrapie prion preparations by improved return refocusing gel electrophoresis

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12 December 2020

Alpha-synuclein cooperates with CSPalpha in preventing neurodegeneration

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12 December 2020

The highways and byways of prion protein trafficking

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12 December 2020

New concepts on the structure of the neuronal networks: the miniaturization and hierarchical organization of the central nervous system. (Hypothesis).

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12 December 2020

Mechanisms of disease II: cellular protein quality control.

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12 December 2020

The nigrostriatal DA pathway and Parkinson's disease

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12 December 2020

Abundance of intrinsic disorder in protein associated with cardiovascular disease

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12 December 2020

Parkinson's disease alpha-synuclein transgenic mice develop neuronal mitochondrial degeneration and cell death.

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12 December 2020

Multiple hit hypotheses for dopamine neuron loss in Parkinson's disease

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12 December 2020

Prediction of boundaries between intrinsically ordered and disordered protein regions

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12 December 2020

Extended disordered proteins: targeting function with less scaffold

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12 December 2020

Mitochondrial dysfunction and reactive oxygen species in excitotoxicity and apoptosis: implications for the pathogenesis of neurodegenerative diseases

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12 December 2020

Always around, never the same: pathways of amyloid beta induced neurodegeneration throughout the pathogenic cascade of Alzheimer's disease

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Intrinsic disorder and protein function

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12 December 2020

Normal brain ageing: models and mechanisms

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12 December 2020

Synaptic targeting by Alzheimer's-related amyloid beta oligomers.

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12 December 2020

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12 December 2020

Ion channel blockade attenuates aggregated alpha synuclein induction of microglial reactive oxygen species: relevance for the pathogenesis of Parkinson's disease.

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12 December 2020

Intrinsic disorder is a common feature of hub proteins from four eukaryotic interactomes

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12 December 2020

Mutation in the alpha-synuclein gene identified in families with Parkinson's disease

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12 December 2020

Protein aggregation and neurodegenerative disease

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12 December 2020

The proteasome in brain aging

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12 December 2020

Solution structure of a 142-residue recombinant prion protein corresponding to the infectious fragment of the scrapie isoform

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12 December 2020

Biochemical aspects of the neuroprotective mechanism of PTEN-induced kinase-1 (PINK1)

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Aspects of neural plasticity in the central nervous system-VII. Theoretical aspects of brain communication and computation.

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12 December 2020

Protein aggregation and aggregate toxicity: new insights into protein folding, misfolding diseases and biological evolution

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Alzheimer's disease-affected brain: presence of oligomeric A beta ligands (ADDLs) suggests a molecular basis for reversible memory loss

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12 December 2020

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12 December 2020

How proteins come together in the plasma membrane and function in macromolecular assemblies: focus on receptor mosaics.

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12 December 2020

HtrA2 and Parkinson's disease: think PINK?

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12 December 2020

Implications of macromolecular crowding for protein assembly.

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12 December 2020

Does a vegan diet reduce risk for Parkinson's disease?

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12 December 2020

Protein flexibility and intrinsic disorder

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12 December 2020

Calcium and neurodegeneration

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12 December 2020

Mitochondrial damage and intralysosomal degradation in cellular aging

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12 December 2020

Possible role of intramembrane receptor-receptor interactions in memory and learning via formation of long-lived heteromeric complexes: focus on motor learning in the basal ganglia.

1 reference

12 December 2020

Pink1, Parkin, DJ-1 and mitochondrial dysfunction in Parkinson's disease

1 reference

12 December 2020

Neuropathology, biochemistry, and biophysics of alpha-synuclein aggregation

1 reference

12 December 2020

Gastric alpha-synuclein immunoreactive inclusions in Meissner's and Auerbach's plexuses in cases staged for Parkinson's disease-related brain pathology

1 reference

12 December 2020

Structural studies of the scrapie prion protein using mass spectrometry and amino acid sequencing.

1 reference

12 December 2020

Is epilepsy a progressive disorder? Prospects for new therapeutic approaches in temporal-lobe epilepsy

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12 December 2020

Plasma homocysteine as a risk factor for dementia and Alzheimer's disease

1 reference

12 December 2020

Absence of inclusion body formation in the MPTP mouse model of Parkinson's disease

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12 December 2020

Gene expression profiling of sporadic Parkinson's disease substantia nigra pars compacta reveals impairment of ubiquitin-proteasome subunits, SKP1A, aldehyde dehydrogenase, and chaperone HSC-70.

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12 December 2020

Understanding neuronal molecular networks builds on neuronal cellular network architecture

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12 December 2020

Substrate specificity and redox potential of AhpC, a bacterial peroxiredoxin

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12 December 2020

Neural activity controls the synaptic accumulation of alpha-synuclein.

1 reference

12 December 2020

Interface between tauopathies and synucleinopathies: A tale of two proteins

1 reference

12 December 2020

Allosteric modulation of dopamine D2 receptors by homocysteine

1 reference

12 December 2020

Calcium, ageing, and neuronal vulnerability in Parkinson's disease

1 reference

12 December 2020

The aggregation and fibrillation of alpha-synuclein

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12 December 2020

Synaptic vesicle depletion correlates with attenuated synaptic responses to prolonged repetitive stimulation in mice lacking alpha-synuclein

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12 December 2020

More than just two peas in a pod: common amyloidogenic properties of tau and alpha-synuclein in neurodegenerative diseases

1 reference

12 December 2020

beta-amyloid peptides enhance alpha-synuclein accumulation and neuronal deficits in a transgenic mouse model linking Alzheimer's disease and Parkinson's disease

1 reference

12 December 2020

Expanding insights of mitochondrial dysfunction in Parkinson's disease.

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12 December 2020

Staging of brain pathology related to sporadic Parkinson's disease

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12 December 2020

The concept of trophic units in the central nervous system

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12 December 2020

Prion diseases and the BSE crisis

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12 December 2020

Expansion of the calcium hypothesis of brain aging and Alzheimer's disease: minding the store

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12 December 2020

Role of alpha-synuclein in presynaptic dopamine recruitment.

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12 December 2020

Oxidative metabolites of 5-S-cysteinyldopamine inhibit the alpha-ketoglutarate dehydrogenase complex: possible relevance to the pathogenesis of Parkinson's disease

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12 December 2020

Neuromelanin of the substantia nigra: a neuronal black hole with protective and toxic characteristics

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12 December 2020

Role of cooperativity in protein folding and protein mosaic assemblage relevance for protein conformational diseases.

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12 December 2020

PINK1 protein in normal human brain and Parkinson's disease

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12 December 2020

10.1007/S00702-008-0072-1

Identifiers

DOI

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18 August 2017

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