(Q37185659)

English

The antiepileptic drug mephobarbital is not transported by P-glycoprotein or multidrug resistance protein 1 at the blood-brain barrier: a positron emission tomography study

scientific article published on 17 February 2012

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

The antiepileptic drug mephobarbital is not transported by P-glycoprotein or multidrug resistance protein 1 at the blood-brain barrier: a positron emission tomography study (English)

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

1 reference

ChEBI release 2020-05-28

blood–brain barrier

1 reference

based on heuristic

inferred from title

multiple drug resistance

1 reference

based on heuristic

inferred from title

positron emission tomography

1 reference

based on heuristic

inferred from title

Marion Bankstahl

object named as

Marion Bankstahl

5

0 references

Severin Mairinger

object named as

Severin Mairinger

1

0 references

Claudia Kuntner

object named as

Claudia Kuntner

3

0 references

object named as

Oliver Langer

11

0 references

author name string

Jens P Bankstahl

2

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

Kerstin Römermann

4

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

Thomas Wanek

6

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

Johann Stanek

7

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

Wolfgang Löscher

8

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

Markus Müller

9

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

Thomas Erker

10

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

language of work or name

1 reference

based on heuristic

inferred from title

publication date

17 February 2012

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

Epilepsy Research

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

100

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

1-2

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

93-103

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

Do ATP-binding cassette transporters cause pharmacoresistance in epilepsy? Problems and approaches in determining which antiepileptic drugs are affected

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3778256

6 September 2017

In vitro transport profile of carbamazepine, oxcarbazepine, eslicarbazepine acetate, and their active metabolites by human P-glycoprotein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3778256

6 September 2017

A novel positron emission tomography imaging protocol identifies seizure-induced regional overactivity of P-glycoprotein at the blood-brain barrier

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3778256

6 September 2017

PET and SPECT radiotracers to assess function and expression of ABC transporters in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3778256

6 September 2017

Dose-response assessment of tariquidar and elacridar and regional quantification of P-glycoprotein inhibition at the rat blood-brain barrier using (R)-[(11)C]verapamil PET.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3778256

6 September 2017

A pilot study to assess the efficacy of tariquidar to inhibit P-glycoprotein at the human blood-brain barrier with (R)-11C-verapamil and PET

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3778256

6 September 2017

Imaging the function of P-glycoprotein with radiotracers: pharmacokinetics and in vivo applications

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3778256

6 September 2017

On the rate and extent of drug delivery to the brain.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3778256

6 September 2017

Tariquidar (XR9576): a P-glycoprotein drug efflux pump inhibitor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3778256

6 September 2017

Molecular and cellular mechanisms of pharmacoresistance in epilepsy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3778256

6 September 2017

Drug resistance in brain diseases and the role of drug efflux transporters.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3778256

6 September 2017

Role of drug efflux transporters in the brain for drug disposition and treatment of brain diseases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3778256

6 September 2017

Functional expression of the multidrug resistance protein 1 in microglia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3778256

6 September 2017

Clinical aspects and biological bases of drug-resistant epilepsies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3778256

6 September 2017

Clinical experience with MK-571. A potent and specific LTD4 receptor antagonist

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3778256

6 September 2017

In vitro concentration dependent transport of phenytoin and phenobarbital, but not ethosuximide, by human P-glycoprotein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3778256

14 September 2017

Evaluation of transport of common antiepileptic drugs by human multidrug resistance-associated proteins (MRP1, 2 and 5) that are overexpressed in pharmacoresistant epilepsy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3778256

14 September 2017

Identification of novel specific and general inhibitors of the three major human ATP-binding cassette transporters P-gp, BCRP and MRP2 among registered drugs.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3778256

14 September 2017

Several major antiepileptic drugs are substrates for human P-glycoprotein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3778256

14 September 2017

Differences in the transport of the antiepileptic drugs phenytoin, levetiracetam and carbamazepine by human and mouse P-glycoprotein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3778256

14 September 2017

Brain regional pharmacokinetics of 11C-labeled diphenylhydantoin: positron emission tomography in humans.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3778256

26 June 2018

Resistance to antiepileptic drugs and expression of P-glycoprotein in two rat models of status epilepticus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3778256

3 September 2018

Valproic acid is not a substrate for P-glycoprotein or multidrug resistance proteins 1 and 2 in a number of in vitro and in vivo transport assays

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3778256

3 September 2018

The multidrug transporter hypothesis of drug resistance in epilepsy: Proof-of-principle in a rat model of temporal lobe epilepsy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3778256

3 September 2018

Inhibition of the multidrug transporter P-glycoprotein improves seizure control in phenytoin-treated chronic epileptic rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3778256

3 September 2018

P-Glycoprotein-mediated efflux of phenobarbital, lamotrigine, and felbamate at the blood-brain barrier: evidence from microdialysis experiments in rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3778256

3 September 2018

The synthesis of some 11C-labelled antiepileptic drugs with potential utility as radiopharmaceuticals: Hydantoins and barbiturates

1 reference

https://pubmed.ncbi.nlm.nih.gov/22342565

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A simple synthesis of [11C]methyl triflate

1 reference

https://pubmed.ncbi.nlm.nih.gov/22342565

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of the liver in the metabolic disposition of mephoparbital

1 reference

https://pubmed.ncbi.nlm.nih.gov/22342565

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Peripheral metabolism of (R)-[11C]verapamil in epilepsy patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/22342565

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1016/J.EPLEPSYRES.2012.01.012

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

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