(Q37209562)

19 August 2017

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title

Targeted gene insertion for molecular medicine (English)

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19 August 2017

3

Zoltán Ivics

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19 August 2017

2

Zsuzsanna Izsvák

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19 August 2017

Katrin Voigt

1

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19 August 2017

publication date

8 July 2008

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Journal of Molecular Medicine

19 August 2017

published in

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19 August 2017

volume

86

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19 August 2017

issue

11

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19 August 2017

page(s)

1205-1219

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Technology transfer from worms and flies to vertebrates: transposition-based genome manipulations and their future perspectives

19 August 2017

cites work

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12 December 2020

Isolation of cDNAs encoding novel transcription coactivators p52 and p75 reveals an alternate regulatory mechanism of transcriptional activation

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12 December 2020

piggyBac is a flexible and highly active transposon as compared to sleeping beauty, Tol2, and Mos1 in mammalian cells

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12 December 2020

Gene therapy with recombinant adenovirus vectors: evaluation of the host immune response

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12 December 2020

Molecular reconstruction of Sleeping Beauty, a Tc1-like transposon from fish, and its transposition in human cells

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12 December 2020

Chimeric Mos1 and piggyBac transposases result in site-directed integration

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12 December 2020

Common physical properties of DNA affecting target site selection of sleeping beauty and other Tc1/mariner transposable elements.

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12 December 2020

Site-specific integration of functional transgenes into the human genome by adeno/AAV hybrid vectors.

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12 December 2020

Adeno-associated virus (AAV) site-specific recombination does not require a Rep-dependent origin of replication within the AAV terminal repeat

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12 December 2020

Transcription start regions in the human genome are favored targets for MLV integration

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12 December 2020

Protein interactions involved in tRNA gene-specific integration of Dictyostelium discoideum non-long terminal repeat retrotransposon TRE5-A.

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12 December 2020

Mutational analysis of the transcription factor IIIB-DNA target of Ty3 retroelement integration

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12 December 2020

A truncation mutant of the 95-kilodalton subunit of transcription factor IIIC reveals asymmetry in Ty3 integration

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12 December 2020

Directed integration of viral DNA mediated by fusion proteins consisting of human immunodeficiency virus type 1 integrase and Escherichia coli LexA protein

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12 December 2020

Targeting of the yeast Ty5 retrotransposon to silent chromatin is mediated by interactions between integrase and Sir4p

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12 December 2020

TFIIIB subunit Bdp1p is required for periodic integration of the Ty1 retrotransposon and targeting of Isw2p to S. cerevisiae tDNAs

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12 December 2020

The Frog Prince: a reconstructed transposon from Rana pipiens with high transpositional activity in vertebrate cells

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12 December 2020

Asymmetric replication in vitro from a human sequence element is dependent on adeno-associated virus Rep protein

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12 December 2020

LEDGF/p75 determines cellular trafficking of diverse lentiviral but not murine oncoretroviral integrase proteins and is a component of functional lentiviral preintegration complexes

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12 December 2020

Tethering human immunodeficiency virus 1 integrase to a DNA site directs integration to nearby sequences

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12 December 2020

Integration targeting by avian sarcoma-leukosis virus and human immunodeficiency virus in the chicken genome

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12 December 2020

The recombination signals for adeno-associated virus site-specific integration

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12 December 2020

Adeno-associated virus (AAV) Rep proteins mediate complex formation between AAV DNA and its integration site in human DNA

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12 December 2020

Molecular analysis of chromosomal rearrangements in mammalian cells after phiC31-mediated integration

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12 December 2020

HIV-1 integration in the human genome favors active genes and local hotspots

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12 December 2020

Functional zinc finger/sleeping beauty transposase chimeras exhibit attenuated overproduction inhibition

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12 December 2020

Targeting of retroviral integrase by fusion to a heterologous DNA binding domain: in vitro activities and incorporation of a fusion protein into viral particles

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12 December 2020

Immune responses to lentiviral vectors.

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12 December 2020

Efficient transposition of the piggyBac (PB) transposon in mammalian cells and mice

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12 December 2020

Adenoviral vectors for gene transfer and therapy

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12 December 2020

Dictyostelium mobile elements: strategies to amplify in a compact genome

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12 December 2020

Nonviral gene therapy

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12 December 2020

Correction of ADA-SCID by stem cell gene therapy combined with nonmyeloablative conditioning

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12 December 2020

Transposition from a gutless adeno-transposon vector stabilizes transgene expression in vivo

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12 December 2020

Human immunodeficiency virus type 1 incorporated with fusion proteins consisting of integrase and the designed polydactyl zinc finger protein E2C can bias integration of viral DNA into a predetermined chromosomal region in human cells

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12 December 2020

AAV serotype 2 vectors preferentially integrate into active genes in mice

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12 December 2020

Engineering proteins that bind, move, make and break DNA

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12 December 2020

Phi c31 integrase induces chromosomal aberrations in primary human fibroblasts

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12 December 2020

Sleeping beauty: a novel cancer gene discovery tool

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12 December 2020

Application of SFHR to gene therapy of monogenic disorders

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12 December 2020

Chance or necessity? Insertional mutagenesis in gene therapy and its consequences

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12 December 2020

Satellite DNA-based artificial chromosomes for use in gene therapy.

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12 December 2020

Target-site preferences of Sleeping Beauty transposons.

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12 December 2020

In vitro site-specific integration of bacteriophage DNA catalyzed by a recombinase of the resolvase/invertase family

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12 December 2020

Chimeric recombinases with designed DNA sequence recognition

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12 December 2020

Integration specificity of phage phiC31 integrase in the human genome

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12 December 2020

Epstein-Barr virus latent nuclear antigens can induce metastasis in a nude mouse model

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12 December 2020

High-resolution genome-wide mapping of transposon integration in mammals

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12 December 2020

Integrated maps of the chromosomes in Dictyostelium discoideum

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12 December 2020

Cellular and humoral immune responses to adenoviral vectors containing factor IX gene: tolerization of factor IX and vector antigens allows for long-term expression

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12 December 2020

Tethering human immunodeficiency virus type 1 preintegration complexes to target DNA promotes integration at nearby sites

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12 December 2020

Neuronal precursor-restricted transduction via in utero CNS gene delivery of a novel bipartite HSV amplicon/transposase hybrid vector

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12 December 2020

PiggyBac transposon-mediated gene transfer in human cells

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12 December 2020

Improved properties of FLP recombinase evolved by cycling mutagenesis

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12 December 2020

Gene editing in human stem cells using zinc finger nucleases and integrase-defective lentiviral vector delivery

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12 December 2020

What are the consequences of the fourth case?

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12 December 2020

Harnessing a high cargo-capacity transposon for genetic applications in vertebrates

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12 December 2020

Tn7: smarter than we thought

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12 December 2020

Transposons for gene therapy!

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12 December 2020

Site-specific integration with phiC31 integrase for prolonged expression of therapeutic genes

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12 December 2020

Growth inhibition and DNA damage induced by Cre recombinase in mammalian cells

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12 December 2020

Helper-dependent adenovirus vectors elicit intact innate but attenuated adaptive host immune responses in vivo

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12 December 2020

Mammalian genomes contain active recombinase recognition sites

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12 December 2020

Epstein-Barr virus sustains Burkitt's lymphomas and Hodgkin's disease

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12 December 2020

HIV-1 proviral DNA excision using an evolved recombinase

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12 December 2020

SAF-Box, a conserved protein domain that specifically recognizes scaffold attachment region DNA.

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12 December 2020

Requirement of RNA polymerase III transcription factors for in vitro position-specific integration of a retroviruslike element

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12 December 2020

A vector based on the SV40 origin of replication and chromosomal S/MARs replicates episomally in CHO cells

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12 December 2020

Transcriptional silencing of Ty1 elements in the RDN1 locus of yeast

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12 December 2020

Targeted insertion of exogenous DNA into the eukaryotic genome by the Cre recombinase

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12 December 2020

Human gene targeting by viral vectors

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12 December 2020

Episomal persistence of recombinant adenoviral vector genomes during the cell cycle in vivo

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12 December 2020

Integration of adeno-associated virus (AAV) and recombinant AAV vectors

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12 December 2020

The artificial zinc finger coding gene 'Jazz' binds the utrophin promoter and activates transcription

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12 December 2020

Transcriptional activities of the Sleeping Beauty transposon and shielding its genetic cargo with insulators.

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12 December 2020

Targeted Sleeping Beauty transposition in human cells

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12 December 2020

Retroviral DNA integration: ASLV, HIV, and MLV show distinct target site preferences

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12 December 2020

The Saccharomyces retrotransposon Ty5 integrates preferentially into regions of silent chromatin at the telomeres and mating loci

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12 December 2020

Toward controlling gene expression at will: specific regulation of the erbB-2/HER-2 promoter by using polydactyl zinc finger proteins constructed from modular building blocks

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12 December 2020

Sustained correction of X-linked severe combined immunodeficiency by ex vivo gene therapy

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12 December 2020

Transposable elements and genome organization: a comprehensive survey of retrotransposons revealed by the complete Saccharomyces cerevisiae genome sequence

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12 December 2020

Modulating target site selection during human immunodeficiency virus DNA integration in vitro with an engineered tethering factor

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12 December 2020

Transposition and targeting of the prokaryotic mobile element IS30 in zebrafish.

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12 December 2020

Transfer RNA gene-targeted integration: an adaptation of retrotransposable elements to survive in the compact Dictyostelium discoideum genome

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12 December 2020

Involvement of a bifunctional, paired-like DNA-binding domain and a transpositional enhancer in Sleeping Beauty transposition

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12 December 2020

Tol2: a versatile gene transfer vector in vertebrates

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12 December 2020

Zinc Finger Tools: custom DNA-binding domains for transcription factors and nucleases

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12 December 2020

Fusion proteins consisting of human immunodeficiency virus type 1 integrase and the designed polydactyl zinc finger protein E2C direct integration of viral DNA into specific sites

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12 December 2020

Somatic integration of an oncogene-harboring Sleeping Beauty transposon models liver tumor development in the mouse

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12 December 2020

Transposable element in fish

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12 December 2020

LMO2-associated clonal T cell proliferation in two patients after gene therapy for SCID-X1

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12 December 2020

The DNA segregation mechanism of Epstein-Barr virus nuclear antigen 1

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12 December 2020

Site-specific Tn7 transposition into the human genome

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12 December 2020

Engineering chromosomal rearrangements in mice

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12 December 2020

Towards safe, non-viral therapeutic gene expression in humans.

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12 December 2020

A role for LEDGF/p75 in targeting HIV DNA integration

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12 December 2020

Site-directed transposon integration in human cells

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12 December 2020

Targeted integration of functional human ATM cDNA into genome mediated by HSV/AAV hybrid amplicon vector

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12 December 2020

Structure-based redesign of the dimerization interface reduces the toxicity of zinc-finger nucleases

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12 December 2020

Controlling integration specificity of a yeast retrotransposon

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12 December 2020

Fatal systemic inflammatory response syndrome in a ornithine transcarbamylase deficient patient following adenoviral gene transfer

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12 December 2020

Retroviral DNA integration: viral and cellular determinants of target-site selection

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12 December 2020

Site-specific genomic integration in mammalian cells mediated by phage phiC31 integrase

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12 December 2020

10.1007/S00109-008-0381-8

Identifiers

DOI

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release_wrgmu7xfk5ah7e7ckk2phtfhji

19 August 2017

Fatcat ID

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Fatcat

https://api.fatcat.wiki/v0/release/wrgmu7xfk5ah7e7ckk2phtfhji

24 November 2022

mapped directly with Wikidata item

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