(Q37241002)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27313051%20AND%20SRC:MED&resulttype=core&format=json

14 March 2020

title

T helper 1 immunity requires complement-driven NLRP3 inflammasome activity in CD4⁺ T cells (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27313051%20AND%20SRC:MED&resulttype=core&format=json

14 March 2020

1 reference

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27313051%20AND%20SRC:MED&resulttype=core&format=json

14 March 2020

Trent M. Woodruff

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27313051%20AND%20SRC:MED&resulttype=core&format=json

14 March 2020

Luke A. J. O'Neill

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27313051%20AND%20SRC:MED&resulttype=core&format=json

14 March 2020

Rebecca Coll

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27313051%20AND%20SRC:MED&resulttype=core&format=json

14 March 2020

Peter N. Monk

15

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27313051%20AND%20SRC:MED&resulttype=core&format=json

14 March 2020

Matthew A. Cooper

16

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27313051%20AND%20SRC:MED&resulttype=core&format=json

14 March 2020

Behdad Afzali

18

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27313051%20AND%20SRC:MED&resulttype=core&format=json

14 March 2020

Helen J Lachmann

19

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27313051%20AND%20SRC:MED&resulttype=core&format=json

14 March 2020

Andrew P Cope

20

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27313051%20AND%20SRC:MED&resulttype=core&format=json

14 March 2020

Claudia Kemper

22

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27313051%20AND%20SRC:MED&resulttype=core&format=json

14 March 2020

12

Alan Sher

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27313051%20AND%20SRC:MED&resulttype=core&format=json

14 March 2020

author name string

Giuseppina Arbore

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27313051%20AND%20SRC:MED&resulttype=core&format=json

14 March 2020

Erin E West

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27313051%20AND%20SRC:MED&resulttype=core&format=json

14 March 2020

Rosanne Spolski

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27313051%20AND%20SRC:MED&resulttype=core&format=json

14 March 2020

Andreas Klos

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27313051%20AND%20SRC:MED&resulttype=core&format=json

14 March 2020

Claudia Rheinheimer

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27313051%20AND%20SRC:MED&resulttype=core&format=json

14 March 2020

Pavel Dutow

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27313051%20AND%20SRC:MED&resulttype=core&format=json

14 March 2020

Zu Xi Yu

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27313051%20AND%20SRC:MED&resulttype=core&format=json

14 March 2020

Warren J Leonard

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27313051%20AND%20SRC:MED&resulttype=core&format=json

14 March 2020

Jörg Köhl

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27313051%20AND%20SRC:MED&resulttype=core&format=json

14 March 2020

Matthew Arno

17

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27313051%20AND%20SRC:MED&resulttype=core&format=json

14 March 2020

Katrin D Mayer-Barber

21

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27313051%20AND%20SRC:MED&resulttype=core&format=json

14 March 2020

language of work or name

English

0 references

publication date

1 June 2016

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27313051%20AND%20SRC:MED&resulttype=core&format=json

14 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27313051%20AND%20SRC:MED&resulttype=core&format=json

14 March 2020

volume

352

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27313051%20AND%20SRC:MED&resulttype=core&format=json

14 March 2020

issue

6292

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27313051%20AND%20SRC:MED&resulttype=core&format=json

14 March 2020

page(s)

aad1210

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27313051%20AND%20SRC:MED&resulttype=core&format=json

describes a project that uses

14 March 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC5015487/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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Complement Regulates Nutrient Influx and Metabolic Reprogramming during Th1 Cell Responses

6 September 2017

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Cell stress increases ATP release in NLRP3 inflammasome-mediated autoinflammatory diseases, resulting in cytokine imbalance

6 September 2017

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6 September 2017

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Nlrp3-inflammasome activation in non-myeloid-derived cells aggravates diabetic nephropathy

6 September 2017

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6 September 2017

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6 September 2017

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Cholesterol crystals induce complement-dependent inflammasome activation and cytokine release

6 September 2017

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Cell death by pyroptosis drives CD4 T-cell depletion in HIV-1 infection

6 September 2017

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Intracellular complement activation sustains T cell homeostasis and mediates effector differentiation

6 September 2017

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6 September 2017

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6 September 2017

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IL-1 enhances expansion, effector function, tissue localization, and memory response of antigen-specific CD8 T cells

6 September 2017

1 reference

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Mitochondria are required for antigen-specific T cell activation through reactive oxygen species signaling.

6 September 2017

1 reference

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NLRP3 is activated in Alzheimer's disease and contributes to pathology in APP/PS1 mice

6 September 2017

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6 September 2017

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NLRP3 inflammasome activation in retinal pigment epithelial cells by lysosomal destabilization: implications for age-related macular degeneration

6 September 2017

1 reference

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Host-dependent control of early regulatory and effector T-cell differentiation underlies the genetic susceptibility of RAG2-deficient mouse strains to transfer colitis.

6 September 2017

1 reference

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The CD46-Jagged1 interaction is critical for human TH1 immunity

6 September 2017

1 reference

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The transcription factor T-bet regulates intestinal inflammation mediated by interleukin-7 receptor+ innate lymphoid cells.

6 September 2017

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6 September 2017

1 reference

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C5aR expression in a novel GFP reporter gene knockin mouse: implications for the mechanism of action of C5aR signaling in T cell immunity

6 September 2017

1 reference

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Insights into the regulation of protein abundance from proteomic and transcriptomic analyses

6 September 2017

1 reference

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The NLRP3 inflammasome in health and disease: the good, the bad and the ugly

6 September 2017

1 reference

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Inflammasomes and autoimmunity

6 September 2017

1 reference

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Complement: a key system for immune surveillance and homeostasis

6 September 2017

1 reference

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Complement regulator CD46 temporally regulates cytokine production by conventional and unconventional T cells

6 September 2017

1 reference

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6 September 2017

1 reference

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The NLRP3 inflammasome: a sensor for metabolic danger?

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5015487

The C5a receptor (C5aR) C5L2 is a modulator of C5aR-mediated signal transduction.

6 September 2017

1 reference

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In vivo regulation of interleukin 1beta in patients with cryopyrin-associated periodic syndromes

6 September 2017

1 reference

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IL-1 acts directly on CD4 T cells to enhance their antigen-driven expansion and differentiation

6 September 2017

1 reference

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IL-1, IL-18, and IL-33 families of cytokines

6 September 2017

1 reference

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Locally produced complement fragments C5a and C3a provide both costimulatory and survival signals to naive CD4+ T cells

6 September 2017

1 reference

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Alterations in CD46-mediated Tr1 regulatory T cells in patients with multiple sclerosis

6 September 2017

1 reference

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Therapeutic activity of C5a receptor antagonists in a rat model of neurodegeneration

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5015487

An anti-inflammatory function for the complement anaphylatoxin C5a-binding protein, C5L2

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5015487

Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5015487

NLRs join TLRs as innate sensors of pathogens

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5015487

C5a mutants are potent antagonists of the C5a receptor (CD88) and of C5L2: position 69 is the locus that determines agonism or antagonism

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5015487

Biologic basis for interleukin-1 in disease

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5015487

Cloning of a new cytokine that induces IFN-gamma production by T cells

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5015487

New developments in C5a receptor signaling

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5015487

The human complement fragment receptor, C5L2, is a recycling decoy receptor.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5015487

Signaling through the adaptor molecule MyD88 in CD4+ T cells is required to overcome suppression by regulatory T cells

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5015487

The C terminus of the human C5a receptor (CD88) is required for normal ligand-dependent receptor internalization

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5015487

IL-1β mediates chronic intestinal inflammation by promoting the accumulation of IL-17A secreting innate lymphoid cells and CD4(+) Th17 cells

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5015487

A crucial role for interleukin (IL)-1 in the induction of IL-17-producing T cells that mediate autoimmune encephalomyelitis.

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5015487

Monitoring and cell-specific deletion of C5aR1 using a novel floxed GFP-C5aR1 reporter knock-in mouse.

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5015487

C5a, but not C5a-des Arg, induces upregulation of heteromer formation between complement C5a receptors C5aR and C5L2.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5015487

Pathogen-induced human TH17 cells produce IFN-γ or IL-10 and are regulated by IL-1β.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5015487

Two SNPs in NLRP3 gene are involved in the predisposition to type-1 diabetes and celiac disease in a pediatric population from northeast Brazil.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5015487

Interleukin-1 and IL-23 induce innate IL-17 production from gammadelta T cells, amplifying Th17 responses and autoimmunity.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5015487

Human C3 deficiency associated with impairments in dendritic cell differentiation, memory B cells, and regulatory T cells.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5015487

IL-1alpha and IL-1beta are endogenous mediators linking cell injury to the adaptive alloimmune response.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5015487

Protective and aggravating effects of Nlrp3 inflammasome activation in IBD models: influence of genetic and environmental factors

3 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27313051

12 December 2020

inferred from PubMed ID database lookup

Genetic variation in proteins of the cryopyrin inflammasome influences susceptibility and severity of rheumatoid arthritis (The Swedish TIRA project)

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27313051

12 December 2020

inferred from PubMed ID database lookup

Complement--tapping into new sites and effector systems

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27313051

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1126/SCIENCE.AAD1210

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27313051%20AND%20SRC:MED&resulttype=core&format=json

14 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27313051%20AND%20SRC:MED&resulttype=core&format=json

14 March 2020

1 reference