(Q33423703)

26084023

26 July 2017

title

Complement Regulates Nutrient Influx and Metabolic Reprogramming during Th1 Cell Responses (English)

1 reference

26 July 2017

1

1 reference

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13 June 2020

Sarah Dimeloe

2

1 reference

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13 June 2020

Gaelle Le Friec

3

1 reference

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13 June 2020

Giovanni A Povoleri

6

1 reference

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13 June 2020

Marco Fischer

7

1 reference

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13 June 2020

Behdad Afzali

14

1 reference

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13 June 2020

Paul Lavender

15

1 reference

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13 June 2020

Claudia Kemper

17

1 reference

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13 June 2020

4

Alexander Navarini

1 reference

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13 June 2020

13

Lionel Couzi

1 reference

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13 June 2020

author name string

Giuseppina Arbore

5

1 reference

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13 June 2020

Réka Belle

8

1 reference

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13 June 2020

Jordan Loeliger

9

1 reference

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13 June 2020

Leyla Develioglu

10

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13 June 2020

Glenn R Bantug

11

1 reference

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13 June 2020

Julie Watson

12

1 reference

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13 June 2020

Christoph Hess

16

1 reference

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13 June 2020

language of work or name

English

0 references

publication date

1 June 2015

1 reference

26 July 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26084023%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

volume

42

1 reference

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13 June 2020

issue

6

1 reference

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13 June 2020

page(s)

1033-1047

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26084023%20AND%20SRC:MED&resulttype=core&format=json

Notch controls the survival of memory CD4+ T cells by regulating glucose uptake

13 June 2020

cites work

1 reference

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Metabolic programming and PDHK1 control CD4+ T cell subsets and inflammation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4518498

Integrating canonical and metabolic signalling programmes in the regulation of T cell responses

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4518498

The glucose transporter Glut1 is selectively essential for CD4 T cell activation and effector function

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4518498

Adenovirus E4ORF1-induced MYC activation promotes host cell anabolic glucose metabolism and virus replication

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4518498

Regulation of mTORC1 by amino acids

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4518498

Intracellular complement activation sustains T cell homeostasis and mediates effector differentiation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4518498

Fueling immunity: insights into metabolism and lymphocyte function

21 June 2018

1 reference

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LAT1 is a critical transporter of essential amino acids for immune reactions in activated human T cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4518498

CD8 memory T cells have a bioenergetic advantage that underlies their rapid recall ability.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4518498

Rheb and Rags come together at the lysosome to activate mTORC1.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4518498

Posttranscriptional control of T cell effector function by aerobic glycolysis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4518498

Control of amino-acid transport by antigen receptors coordinates the metabolic reprogramming essential for T cell differentiation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4518498

Mitochondria are required for antigen-specific T cell activation through reactive oxygen species signaling.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4518498

Metabolic regulation of T lymphocytes

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4518498

The CD46-Jagged1 interaction is critical for human TH1 immunity

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4518498

Ragulator is a GEF for the rag GTPases that signal amino acid levels to mTORC1

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4518498

Metabolism and autophagy in the immune system: immunometabolism comes of age.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4518498

Metabolic pathways in T cell fate and function

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4518498

Mitochondrial respiratory capacity is a critical regulator of CD8+ T cell memory development

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4518498

The transcription factor Myc controls metabolic reprogramming upon T lymphocyte activation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4518498

Hypo- and hyperactivated Notch signaling induce a glycolytic switch through distinct mechanisms.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4518498

HIF1alpha-dependent glycolytic pathway orchestrates a metabolic checkpoint for the differentiation of TH17 and Treg cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4518498

The Th1 life cycle: molecular control of IFN-γ to IL-10 switching

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4518498

Cutting edge: distinct glycolytic and lipid oxidative metabolic programs are essential for effector and regulatory CD4+ T cell subsets.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4518498

The dynamic processing of CD46 intracellular domains provides a molecular rheostat for T cell activation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4518498

Complement regulator CD46 temporally regulates cytokine production by conventional and unconventional T cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4518498

Activation of a metabolic gene regulatory network downstream of mTOR complex 1

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4518498

Ragulator-Rag complex targets mTORC1 to the lysosomal surface and is necessary for its activation by amino acids

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4518498

Complement: coming full circle.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4518498

Effects of PI3K catalytic subunit and Akt isoform deficiency on mTOR and p70S6K activation in myoblasts

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4518498

mTORC1 hyperactivity inhibits serum deprivation-induced apoptosis via increased hexokinase II and GLUT1 expression, sustained Mcl-1 expression, and glycogen synthase kinase 3beta inhibition

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4518498

The mTOR kinase differentially regulates effector and regulatory T cell lineage commitment

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4518498

Glucose amplifies fatty acid-induced endoplasmic reticulum stress in pancreatic beta-cells via activation of mTORC1.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4518498

Inherited deficiency of membrane cofactor protein expression and varying manifestations of recurrent atypical hemolytic uremic syndrome in a sibling pair

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4518498

Glucose uptake is limiting in T cell activation and requires CD28-mediated Akt-dependent and independent pathways.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4518498

mTOR controls mitochondrial oxidative function through a YY1-PGC-1alpha transcriptional complex

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4518498

IL-7 promotes Glut1 trafficking and glucose uptake via STAT5-mediated activation of Akt to support T-cell survival

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4518498

Alterations in CD46-mediated Tr1 regulatory T cells in patients with multiple sclerosis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4518498

Genetic and functional analyses of membrane cofactor protein (CD46) mutations in atypical hemolytic uremic syndrome

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4518498

Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4518498

Notch promotes survival of pre-T cells at the beta-selection checkpoint by regulating cellular metabolism

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4518498

Rheb binding to mammalian target of rapamycin (mTOR) is regulated by amino acid sufficiency

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4518498

CD28 delivers a unique signal leading to the selective recruitment of RelA and p52 NF-kappaB subunits on IL-8 and Bcl-xL gene promoters.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4518498

Four viruses, two bacteria, and one receptor: membrane cofactor protein (CD46) as pathogens' magnet

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4518498

Activation of human CD4+ cells with CD3 and CD46 induces a T-regulatory cell 1 phenotype

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4518498

The CD28 signaling pathway regulates glucose metabolism

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4518498

Membrane cofactor protein (MCP; CD46) expression in transgenic mice

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4518498

Cutting edge: CD46, a new costimulatory molecule for T cells, that induces p120CBL and LAT phosphorylation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4518498

T cell activation determined by T cell receptor number and tunable thresholds.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4518498

Membrane cofactor protein (MCP or CD46): newest member of the regulators of complement activation gene cluster

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4518498

Rapid effector function of memory CD8+ T cells requires an immediate-early glycolytic switch

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4518498

Regulation of placental amino acid transporter activity by mammalian target of rapamycin

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4518498

Revving the engine: signal transduction fuels T cell activation.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4518498

Membrane cofactor protein (MCP; CD46). Isoforms differ in protection against the classical pathway of complement

31 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26084023

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

A role for mammalian target of rapamycin in regulating T cell activation versus anergy

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26084023

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Complement--tapping into new sites and effector systems

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26084023

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.IMMUNI.2015.05.024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26084023%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26084023%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

26084023

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26084023%20AND%20SRC:MED&resulttype=core&format=json