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Regulation of mTORC1 by amino acids
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PubMed
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Europe PubMed Central
PMCID
4074565
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24698685%20AND%20SRC:MED&resulttype=core&format=json
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12 March 2020
title
Regulation of mTORC1 by amino acids
(English)
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Europe PubMed Central
PMCID
4074565
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24698685%20AND%20SRC:MED&resulttype=core&format=json
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12 March 2020
author
David M. Sabatini
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2
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Europe PubMed Central
PMCID
4074565
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24698685%20AND%20SRC:MED&resulttype=core&format=json
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12 March 2020
author name string
Liron Bar-Peled
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1
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Crossref
stated in
Europe PubMed Central
PMCID
4074565
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24698685%20AND%20SRC:MED&resulttype=core&format=json
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12 March 2020
language of work or name
English
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publication date
31 March 2014
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Europe PubMed Central
PMCID
4074565
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24698685%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 March 2020
published in
Trends in Cell Biology
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PubMed
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Europe PubMed Central
PMCID
4074565
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24698685%20AND%20SRC:MED&resulttype=core&format=json
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12 March 2020
volume
24
2 references
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PubMed
stated in
Europe PubMed Central
PMCID
4074565
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24698685%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 March 2020
page(s)
400-406
1 reference
stated in
Europe PubMed Central
PMCID
4074565
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24698685%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 March 2020
issue
7
2 references
stated in
PubMed
stated in
Europe PubMed Central
PMCID
4074565
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24698685%20AND%20SRC:MED&resulttype=core&format=json
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12 March 2020
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GbetaL, a positive regulator of the rapamycin-sensitive pathway required for the nutrient-sensitive interaction between raptor and mTOR
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p53 target genes sestrin1 and sestrin2 connect genotoxic stress and mTOR signaling
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21 March 2017
TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signalling
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21 March 2017
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Phosphatidylinositol 3-kinase/Akt pathway regulates tuberous sclerosis tumor suppressor complex by phosphorylation of tuberin
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21 March 2017
The 630-kb lung cancer homozygous deletion region on human chromosome 3p21.3: identification and evaluation of the resident candidate tumor suppressor genes. The International Lung Cancer Chromosome 3p21.3 Tumor Suppressor Gene Consortium
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21 March 2017
Spatial control of the TSC complex integrates insulin and nutrient regulation of mTORC1 at the lysosome
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21 March 2017
GEFs and GAPs: critical elements in the control of small G proteins
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21 March 2017
Phosphorylation and functional inactivation of TSC2 by Erk implications for tuberous sclerosis and cancer pathogenesis
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The tuberous sclerosis protein TSC2 is not required for the regulation of the mammalian target of rapamycin by amino acids and certain cellular stresses
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21 March 2017
Identification of the tuberous sclerosis gene TSC1 on chromosome 9q34
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Identification and characterization of the tuberous sclerosis gene on chromosome 16
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21 March 2017
Mutations in DEPDC5 cause familial focal epilepsy with variable foci
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21 March 2017
The novel lipid raft adaptor p18 controls endosome dynamics by anchoring the MEK-ERK pathway to late endosomes.
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21 March 2017
Kidney-targeted Birt-Hogg-Dube gene inactivation in a mouse model: Erk1/2 and Akt-mTOR activation, cell hyperproliferation, and polycystic kidneys
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21 March 2017
Identification of the tuberous sclerosis complex-2 tumor suppressor gene product tuberin as a target of the phosphoinositide 3-kinase/akt pathway
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mTORC1 senses lysosomal amino acids through an inside-out mechanism that requires the vacuolar H(+)-ATPase
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Autophagy and metabolism
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Molecular mechanisms of mTOR-mediated translational control
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Bidirectional transport of amino acids regulates mTOR and autophagy
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Regulation of TORC1 by Rag GTPases in nutrient response
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7 April 2017
Vacuolar ATPases: rotary proton pumps in physiology and pathophysiology
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7 April 2017
Akt regulates growth by directly phosphorylating Tsc2
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7 April 2017
Amino acid sufficiency and mTOR regulate p70 S6 kinase and eIF-4E BP1 through a common effector mechanism
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7 April 2017
The folliculin tumor suppressor is a GAP for the RagC/D GTPases that signal amino acid levels to mTORC1.
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28 September 2017
Recruitment of folliculin to lysosomes supports the amino acid-dependent activation of Rag GTPases
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28 September 2017
Mutations of DEPDC5 cause autosomal dominant focal epilepsies
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28 September 2017
Signal recognition particle: an essential protein-targeting machine
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28 September 2017
Amino acid signalling upstream of mTOR
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074565
retrieved
28 September 2017
Regulation of mTORC1 by the Rag GTPases is necessary for neonatal autophagy and survival.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074565
retrieved
28 September 2017
The mTOR signaling pathway in the brain: focus on epilepsy and epileptogenesis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074565
retrieved
28 September 2017
Genotype and cognitive phenotype of patients with tuberous sclerosis complex
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074565
retrieved
28 September 2017
Phosphoproteomic analysis identifies Grb10 as an mTORC1 substrate that negatively regulates insulin signaling
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074565
retrieved
28 September 2017
The mTOR-regulated phosphoproteome reveals a mechanism of mTORC1-mediated inhibition of growth factor signaling.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074565
retrieved
28 September 2017
Structure of the human mTOR complex I and its implications for rapamycin inhibition.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074565
retrieved
28 September 2017
The late endosome is essential for mTORC1 signaling
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074565
retrieved
28 September 2017
Regulation of the small GTPase Rheb by amino acids.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074565
retrieved
28 September 2017
The hypoxia-induced paralogs Scylla and Charybdis inhibit growth by down-regulating S6K activity upstream of TSC in Drosophila
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074565
retrieved
28 September 2017
Rheb promotes cell growth as a component of the insulin/TOR signalling network
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074565
retrieved
28 September 2017
Dynein light chains of the Roadblock/LC7 group belong to an ancient protein superfamily implicated in NTPase regulation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074565
retrieved
28 September 2017
Amino acid availability regulates p70 S6 kinase and multiple translation factors
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074565
retrieved
31 May 2018
The response of muscle protein synthesis to nutrient intake in postabsorptive rats: the role of insulin and amino acids.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074565
retrieved
31 May 2018
Cell signalling: nutrient sensing lost in cancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074565
retrieved
28 November 2018
A novel human primary immunodeficiency syndrome caused by deficiency of the endosomal adaptor protein p14.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074565
retrieved
28 November 2018
Rheb is an essential regulator of S6K in controlling cell growth in Drosophila
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074565
retrieved
28 November 2018
TRAPP stimulates guanine nucleotide exchange on Ypt1p
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074565
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28 November 2018
Identifiers
DOI
10.1016/J.TCB.2014.03.003
2 references
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
913873
stated in
Europe PubMed Central
PMCID
4074565
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24698685%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 March 2020
Fatcat ID
release_omjyrpvebnh7he2nuizhegxu5i
1 reference
stated in
Fatcat
reference URL
https://api.fatcat.wiki/v0/release/omjyrpvebnh7he2nuizhegxu5i
retrieved
24 November 2022
based on heuristic
mapped directly with Wikidata item
OpenCitations bibliographic resource ID
913873
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
913873
PMCID
4074565
2 references
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
913873
stated in
Europe PubMed Central
PMCID
4074565
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24698685%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 March 2020
PubMed ID
24698685
2 references
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
913873
stated in
Europe PubMed Central
PMCID
4074565
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24698685%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 March 2020
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