(Q37249438)

19 August 2017

1 reference

title

The power plant of the cell is also a smithy: the emerging role of mitochondria in cellular iron homeostasis (English)

1 reference

19 August 2017

1 reference

2

Roland Lill

1 reference

19 August 2017

Alex D Sheftel

1

1 reference

PubMed ID

18720092

19 August 2017

language of work or name

English

0 references

publication date

1 January 2009

1 reference

19 August 2017

1 reference

19 August 2017

41

1 reference

19 August 2017

2

1 reference

19 August 2017

82-99

1 reference

Role of free radicals and catalytic metal ions in human disease: an overview

19 August 2017

1 reference

https://api.crossref.org/works/10.1080%2F07853890802322229

The role of transferrin in iron transport

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890802322229

Iron accumulation in Alzheimer disease is a source of redox-generated free radicals

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890802322229

The relevance of iron in the pathogenesis of Parkinson's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890802322229

Hereditary causes of disturbed iron homeostasis in the central nervous system

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890802322229

A possible primordial peptide cycle

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890802322229

A specialized mitochondrial molecular chaperone system: a role in formation of Fe/S centers

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890802322229

Iron-sulphur cluster biogenesis and mitochondrial iron homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890802322229

Biosynthesis of heme in mammals

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890802322229

The molecular mechanisms of the metabolism and transport of iron in normal and neoplastic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890802322229

Identification of a ferrireductase required for efficient transferrin-dependent iron uptake in erythroid cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890802322229

Cloning and characterization of a mammalian proton-coupled metal-ion transporter

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890802322229

Intracellular kinetics of iron in reticulocytes: evidence for endosome involvement in iron targeting to mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890802322229

The ferritins: molecular properties, iron storage function and cellular regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890802322229

A human mitochondrial ferritin encoded by an intronless gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890802322229

Human mitochondrial ferritin expressed in HeLa cells incorporates iron and affects cellular iron metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890802322229

Role of ferritin in the control of the labile iron pool in murine erythroleukemia cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890802322229

Tissue-specific expression of ferritin H regulates cellular iron homoeostasis in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890802322229

Overexpression of mitochondrial ferritin causes cytosolic iron depletion and changes cellular iron homeostasis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890802322229

Ferritin iron uptake and release. Structure–function relationships

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890802322229

Ferric ion sequestering agents: kinetics of iron release from ferritin to catechoylamides

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890802322229

Release of iron from ferritin requires lysosomal activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890802322229

Ferroportin-mediated mobilization of ferritin iron precedes ferritin degradation by the proteasome

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890802322229

Transition metal transport in yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890802322229

Yeast, a model organism for iron and copper metabolism studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890802322229

Iron uptake in fungi: a system for every source

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890802322229

Role of PUG1 in inducible porphyrin and heme transport in Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890802322229

Mitoferrin is essential for erythroid iron assimilation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890802322229

A specific role of the yeast mitochondrial carriers MRS3/4p in mitochondrial iron acquisition under iron-limiting conditions

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890802322229

CCC1 is a transporter that mediates vacuolar iron storage in yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890802322229

The biochemistry of heme biosynthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890802322229

p16INK4a induces an age-dependent decline in islet regenerative potential

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890802322229

Human ABCB6 localizes to both the outer mitochondrial membrane and the plasma membrane

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890802322229

Human ABC transporter isoform B6 (ABCB6) localizes primarily in the Golgi apparatus

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890802322229

Vesicular localization of the rat ATP-binding cassette half-transporter rAbcb6.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890802322229

MTABC3, a novel mitochondrial ATP-binding cassette protein involved in iron homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890802322229

Identification of a human mitochondrial ABC transporter, the functional orthologue of yeast Atm1p

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890802322229

The mitochondrial ATP-binding cassette transporter Abcb7 is essential in mice and participates in cytosolic iron-sulfur cluster biogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890802322229

Abcb7, the gene responsible for X-linked sideroblastic anemia with ataxia, is essential for hematopoiesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890802322229

Crystal structure of protoporphyrinogen IX oxidase: a key enzyme in haem and chlorophyll biosynthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890802322229

Terminal steps of haem biosynthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890802322229

Regulation of the stability of chicken embryo liver delta-aminolevulinate synthase mRNA by hemin

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890802322229

Regulation by heme of synthesis and intracellular translocation of delta-aminolevulinate synthase in the liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890802322229

Regulation by heme of mitochondrial protein transport through a conserved amino acid motif

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890802322229

Identification of rate-limiting steps in yeast heme biosynthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890802322229

Maturation of iron-sulfur proteins in eukaryotes: mechanisms, connected processes, and diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890802322229

The Nfs1 interacting protein Isd11 has an essential role in Fe/S cluster biogenesis in mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890802322229

Essential role of Isd11 in mitochondrial iron-sulfur cluster synthesis on Isu scaffold proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890802322229

Structure, function, and formation of biological iron-sulfur clusters

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890802322229

Functional analysis of Arabidopsis genes involved in mitochondrial iron-sulfur cluster assembly

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890802322229

The Arabidopsis chloroplastic NifU-like protein CnfU, which can act as an iron-sulfur cluster scaffold protein, is required for biogenesis of ferredoxin and photosystem I.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890802322229

Components involved in assembly and dislocation of iron-sulfur clusters on the scaffold protein Isu1p

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890802322229

Characterization of iron-sulfur protein assembly in isolated mitochondria. A requirement for ATP, NADH, and reduced iron

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890802322229

An interaction between frataxin and Isu1/Nfs1 that is crucial for Fe/S cluster synthesis on Isu1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890802322229

Iron-sulfur cluster biosynthesis. Characterization of frataxin as an iron donor for assembly of [2Fe-2S] clusters in ISU-type proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890802322229

Grx5 is a mitochondrial glutaredoxin required for the activity of iron/sulfur enzymes

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890802322229

The mitochondrial proteins Atm1p and Nfs1p are essential for biogenesis of cytosolic Fe/S proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890802322229

The yeast scaffold proteins Isu1p and Isu2p are required inside mitochondria for maturation of cytosolic Fe/S proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890802322229

A mitochondrial ferredoxin is essential for biogenesis of cellular iron-sulfur proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890802322229

Frataxin is essential for extramitochondrial Fe-S cluster proteins in mammalian tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890802322229

Maturation of cellular Fe-S proteins: an essential function of mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890802322229

Activation of the iron regulon by the yeast Aft1/Aft2 transcription factors depends on mitochondrial but not cytosolic iron-sulfur protein biogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890802322229

An essential function of the mitochondrial sulfhydryl oxidase Erv1p/ALR in the maturation of cytosolic Fe/S proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890802322229

Maturation of cytosolic iron-sulfur proteins requires glutathione

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890802322229

A novel eukaryotic factor for cytosolic Fe-S cluster assembly

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890802322229

The eukaryotic P loop NTPase Nbp35: an essential component of the cytosolic and nuclear iron-sulfur protein assembly machinery

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890802322229

The cell's cookbook for iron--sulfur clusters: recipes for fool's gold?

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890802322229

The hydrogenase-like Nar1p is essential for maturation of cytosolic and nuclear iron-sulphur proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890802322229

The essential WD40 protein Cia1 is involved in a late step of cytosolic and nuclear iron-sulfur protein assembly

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890802322229

The Cfd1-Nbp35 complex acts as a scaffold for iron-sulfur protein assembly in the yeast cytosol

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890802322229

Aft2p, a novel iron-regulated transcription activator that modulates, with Aft1p, intracellular iron use and resistance to oxidative stress in yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890802322229

A second iron-regulatory system in yeast independent of Aft1p

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890802322229

Subcellular localization of Aft1 transcription factor responds to iron status in Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890802322229

Transcription of the yeast iron regulon does not respond directly to iron but rather to iron-sulfur cluster biosynthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890802322229

Role of glutaredoxin-3 and glutaredoxin-4 in the iron regulation of the Aft1 transcriptional activator in Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890802322229

Glutaredoxins Grx3 and Grx4 regulate nuclear localisation of Aft1 and the oxidative stress response in Saccharomyces cerevisiae.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890802322229

Identification of FRA1 and FRA2 as genes involved in regulating the yeast iron regulon in response to decreased mitochondrial iron-sulfur cluster synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890802322229

Cellular and mitochondrial remodeling upon defects in iron-sulfur protein biogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890802322229

Inhibition of heme biosynthesis prevents transcription of iron uptake genes in yeast.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890802322229

Balancing acts: molecular control of mammalian iron metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890802322229

Molecular control of vertebrate iron homeostasis by iron regulatory proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890802322229

The role of iron regulatory proteins in mammalian iron homeostasis and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890802322229

Structure of dual function iron regulatory protein 1 complexed with ferritin IRE-RNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890802322229

The functional duality of iron regulatory protein 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890802322229

Functions of mitochondrial ISCU and cytosolic ISCU in mammalian iron-sulfur cluster biogenesis and iron homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890802322229

Role of human mitochondrial Nfs1 in cytosolic iron-sulfur protein biogenesis and iron regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890802322229

Iron-sulfur protein maturation in human cells: evidence for a function of frataxin

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890802322229

A role for IOP1 in mammalian cytosolic iron-sulfur protein biogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890802322229

Haem inhibits iron uptake subsequent to endocytosis of transferrin in reticulocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890802322229

Involvement of heme in the degradation of iron-regulatory protein 2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890802322229

Identification of a heme-sensing domain in iron regulatory protein 2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890802322229

Why heme needs to be degraded to iron, biliverdin IXalpha, and carbon monoxide?

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890802322229

Microcytic anemia, erythropoietic protoporphyria, and neurodegeneration in mice with targeted deletion of iron-regulatory protein 2

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890802322229

Human ferrochelatase is an iron-sulfur protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890802322229

Yeast mitochondrial protein, Nfs1p, coordinately regulates iron-sulfur cluster proteins, cellular iron uptake, and iron distribution

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890802322229

Adrenodoxin reductase homolog (Arh1p) of yeast mitochondria required for iron homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890802322229

Regulation of mitochondrial iron accumulation by Yfh1p, a putative homolog of frataxin

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890802322229

Mt-Hsp70 homolog, Ssc2p, required for maturation of yeast frataxin and mitochondrial iron homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890802322229

J-domain protein, Jac1p, of yeast mitochondria required for iron homeostasis and activity of Fe-S cluster proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890802322229

The ABC transporter Atm1p is required for mitochondrial iron homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890802322229

Mitochondrial ferritin expression in erythroid cells from patients with sideroblastic anemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890802322229

In vivo tumor growth is inhibited by cytosolic iron deprivation caused by the expression of mitochondrial ferritin

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890802322229

Enzymatic defect in "X-linked" sideroblastic anemia: molecular evidence for erythroid delta-aminolevulinate synthase deficiency

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890802322229

5-Aminolevulinic acid synthase: mechanism, mutations and medicine

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890802322229

Crystal structure of 5-aminolevulinate synthase, the first enzyme of heme biosynthesis, and its link to XLSA in humans.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890802322229

Positional cloning of the zebrafish sauternes gene: a model for congenital sideroblastic anaemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890802322229

Heme deficiency in erythroid lineage causes differentiation arrest and cytoplasmic iron overload

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890802322229

Transgenic rescue of erythroid 5-aminolevulinate synthase-deficient mice results in the formation of ring sideroblasts and siderocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890802322229

Mutation of a putative mitochondrial iron transporter gene (ABC7) in X-linked sideroblastic anemia and ataxia (XLSA/A)

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890802322229

The heme synthesis defect of mutants impaired in mitochondrial iron-sulfur protein biogenesis is caused by reversible inhibition of ferrochelatase

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890802322229

The role of the iron transporter ABCB7 in refractory anemia with ring sideroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890802322229

Deletion of the mitochondrial carrier genes MRS3 and MRS4 suppresses mitochondrial iron accumulation in a yeast frataxin-deficient strain

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890802322229

Characterization of two homologous yeast genes that encode mitochondrial iron transporters

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890802322229

Friedreich's ataxia: autosomal recessive disease caused by an intronic GAA triplet repeat expansion

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890802322229

Aconitase and mitochondrial iron-sulphur protein deficiency in Friedreich ataxia

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890802322229

Mouse models for Friedreich ataxia exhibit cardiomyopathy, sensory nerve defect and Fe-S enzyme deficiency followed by intramitochondrial iron deposits

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890802322229

Mitochondrial frataxin interacts with ISD11 of the NFS1/ISCU complex and multiple mitochondrial chaperones.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890802322229

Frataxin-mediated iron delivery to ferrochelatase in the final step of heme biosynthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890802322229

Erythroid differentiation and protoporphyrin IX down-regulate frataxin expression in Friend cells: characterization of frataxin expression compared to molecules involved in iron metabolism and hemoglobinization

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890802322229

Assembly and iron-binding properties of human frataxin, the protein deficient in Friedreich ataxia

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890802322229

Iron-induced oligomerization of yeast frataxin homologue Yfh1 is dispensable in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890802322229

The expression of human mitochondrial ferritin rescues respiratory function in frataxin-deficient yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890802322229

The effects of frataxin silencing in HeLa cells are rescued by the expression of human mitochondrial ferritin

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890802322229

Splice mutation in the iron-sulfur cluster scaffold protein ISCU causes myopathy with exercise intolerance

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890802322229

Deficiency of glutaredoxin 5 reveals Fe-S clusters are required for vertebrate haem synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890802322229

The human counterpart of zebrafish shiraz shows sideroblastic-like microcytic anemia and iron overload.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890802322229

IscU as a Scaffold for Iron−Sulfur Cluster Biosynthesis: Sequential Assembly of [2Fe-2S] and [4Fe-4S] Clusters in IscU†

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890802322229

10.1080/07853890802322229

21 January 2018

Identifiers

DOI

1 reference

19 August 2017

1 reference

PubMed ID

18720092