(Q37294298)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27258787%20AND%20SRC:MED&resulttype=core&format=json

3 April 2020

title

Reactivation of mutant p53 by a dietary-related compound phenethyl isothiocyanate inhibits tumor growth (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27258787%20AND%20SRC:MED&resulttype=core&format=json

3 April 2020

author name string

M Aggarwal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27258787%20AND%20SRC:MED&resulttype=core&format=json

3 April 2020

R Saxena

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27258787%20AND%20SRC:MED&resulttype=core&format=json

3 April 2020

E Sinclair

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27258787%20AND%20SRC:MED&resulttype=core&format=json

3 April 2020

Y Fu

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27258787%20AND%20SRC:MED&resulttype=core&format=json

3 April 2020

A Jacobs

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27258787%20AND%20SRC:MED&resulttype=core&format=json

3 April 2020

X Wang

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27258787%20AND%20SRC:MED&resulttype=core&format=json

3 April 2020

I Cruz

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27258787%20AND%20SRC:MED&resulttype=core&format=json

3 April 2020

B Kallakury

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27258787%20AND%20SRC:MED&resulttype=core&format=json

3 April 2020

S C Mueller

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27258787%20AND%20SRC:MED&resulttype=core&format=json

3 April 2020

S D Agostino

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27258787%20AND%20SRC:MED&resulttype=core&format=json

3 April 2020

G Blandino

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27258787%20AND%20SRC:MED&resulttype=core&format=json

3 April 2020

M L Avantaggiati

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27258787%20AND%20SRC:MED&resulttype=core&format=json

3 April 2020

F-L Chung

15

1 reference

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3 April 2020

publication date

3 June 2016

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27258787%20AND%20SRC:MED&resulttype=core&format=json

Cell Death & Differentiation

3 April 2020

published in

1 reference

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3 April 2020

volume

23

1 reference

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3 April 2020

issue

10

1 reference

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3 April 2020

page(s)

1615-1627

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27258787%20AND%20SRC:MED&resulttype=core&format=json

Creative Commons Attribution 4.0 International

3 April 2020

copyright license

start time

3 June 2016

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

exact match

https://scigraph.springernature.com/pub.10.1038/cdd.2016.48

0 references

cites work

Degradation of mutant p53H175 protein by Zn(II) through autophagy.

1 reference

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Dissecting the pathways that destabilize mutant p53: the proteasome or autophagy?

6 September 2017

1 reference

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Keap1-nrf2 signaling: a target for cancer prevention by sulforaphane

6 September 2017

1 reference

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Mutant p53: one name, many proteins

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5041190

Allele-specific p53 mutant reactivation

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5041190

Endogenously induced DNA double strand breaks arise in heterochromatic DNA regions and require ataxia telangiectasia mutated and Artemis for their repair

6 September 2017

1 reference

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Selective depletion of mutant p53 by cancer chemopreventive isothiocyanates and their structure-activity relationships

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5041190

Inhibition of helicase activity by a small molecule impairs Werner syndrome helicase (WRN) function in the cellular response to DNA damage or replication stress

6 September 2017

1 reference

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Intracellular signaling and hepatocellular carcinoma

6 September 2017

1 reference

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The role of SATB1 in breast cancer pathogenesis.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5041190

Phenethyl isothiocyanate inhibits oxidative phosphorylation to trigger reactive oxygen species-mediated death of human prostate cancer cells

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5041190

Cancer preventive isothiocyanates induce selective degradation of cellular alpha- and beta-tubulins by proteasomes

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5041190

Atg5 regulates phenethyl isothiocyanate-induced autophagic and apoptotic cell death in human prostate cancer cells

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5041190

Structure-function-rescue: the diverse nature of common p53 cancer mutants

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5041190

Restoration of p53 function leads to tumour regression in vivo

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5041190

The antioxidant function of the p53 tumor suppressor

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5041190

Isothiocyanates as cancer chemopreventive agents: their biological activities and metabolism in rodents and humans

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5041190

Restoration of the tumor suppressor function to mutant p53 by a low-molecular-weight compound.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5041190

Induction of xenobiotic enzymes by the MAP kinase pathway and the antioxidant or electrophile response element (ARE/EpRE).

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5041190

Phytochemicals from cruciferous plants protect against cancer by modulating carcinogen metabolism

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5041190

Regulation and function of the p53 tumor suppressor protein

6 September 2017

1 reference

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Progression model for pancreatic cancer.

6 September 2017

1 reference

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High metastatic potential in mice inheriting a targeted p53 missense mutation

6 September 2017

1 reference

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Redox modulation of p53 conformation and sequence-specific DNA binding in vitro.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5041190

WAF1, a potential mediator of p53 tumor suppression

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5041190

A common gain of function of p53 cancer mutants in inducing genetic instability

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5041190

Mutant p53 drives invasion by promoting integrin recycling

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5041190

Selective killing of oncogenically transformed cells through a ROS-mediated mechanism by beta-phenylethyl isothiocyanate.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5041190

Phenethyl isothiocyanate-induced apoptosis in PC-3 human prostate cancer cells is mediated by reactive oxygen species-dependent disruption of the mitochondrial membrane potential

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5041190

Phenethyl isothiocyanate and sulforaphane and their N-acetylcysteine conjugates inhibit malignant progression of lung adenomas induced by tobacco carcinogens in A/J mice.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5041190

Phenethyl isothiocyanate-induced apoptosis in p53-deficient PC-3 human prostate cancer cell line is mediated by extracellular signal-regulated kinases.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5041190

28 September 2017

The p53-Bcl-2 connection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5041190

Conversion of glucosinolates to isothiocyanates in humans after ingestion of cooked watercress.

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5041190

Multiple primary cancers in families with Li-Fraumeni syndrome

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5041190

Geldanamycin-stimulated destabilization of mutated p53 is mediated by the proteasome in vivo

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5041190

Gain of function mutations in p53.

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5041190

Distribution and metabolism of the natural anticarcinogen phenethyl isothiocyanate in A/J mice

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5041190

beta-Phenylethyl isothiocyanate-mediated apoptosis in hepatoma HepG2 cells.

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5041190

High-performance liquid chromatography-based determination of total isothiocyanate levels in human plasma: application to studies with 2-phenethyl isothiocyanate

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5041190

Tumor suppressor gene p53 mutations in human prostate cancer

3 September 2018

1 reference

12 December 2020

p53 missense mutations in microdissected high-grade ductal carcinoma in situ of the breast

1 reference

12 December 2020

Essential role of p53 in phenethyl isothiocyanate-induced apoptosis

1 reference

12 December 2020

p53 gene mutation spectrum in hepatocellular carcinoma

1 reference

12 December 2020

Identifiers

DOI

10.1038/CDD.2016.48

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27258787%20AND%20SRC:MED&resulttype=core&format=json

3 April 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27258787%20AND%20SRC:MED&resulttype=core&format=json

3 April 2020

1 reference