(Q37298002)

English

Hypertonic saline is effective in the prevention and treatment of mucus obstruction, but not airway inflammation, in mice with chronic obstructive lung disease

scientific article published on September 2013

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Statements

scholarly article

1 reference

Europe PubMed Central

19 August 2017

Hypertonic saline is effective in the prevention and treatment of mucus obstruction, but not airway inflammation, in mice with chronic obstructive lung disease (English)

1 reference

Europe PubMed Central

19 August 2017

0 references

chronic obstructive pulmonary disease

1 reference

based on heuristic

inferred from title

author name string

Simon Y Graeber

1

1 reference

Europe PubMed Central

19 August 2017

Zhe Zhou-Suckow

2

1 reference

Europe PubMed Central

19 August 2017

Jolanthe Schatterny

3

1 reference

Europe PubMed Central

19 August 2017

Stephanie Hirtz

4

1 reference

Europe PubMed Central

19 August 2017

Richard C Boucher

5

1 reference

Europe PubMed Central

19 August 2017

Marcus A Mall

6

1 reference

Europe PubMed Central

19 August 2017

publication date

1 September 2013

1 reference

Europe PubMed Central

19 August 2017

American Journal of Respiratory Cell and Molecular Biology

1 reference

Europe PubMed Central

19 August 2017

49

1 reference

Europe PubMed Central

19 August 2017

3

1 reference

Europe PubMed Central

19 August 2017

410-417

1 reference

Europe PubMed Central

19 August 2017

CFTR regulates early pathogenesis of chronic obstructive lung disease in βENaC-overexpressing mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3824058

6 September 2017

A periciliary brush promotes the lung health by separating the mucus layer from airway epithelia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3824058

6 September 2017

Inhaled hypertonic saline in infants and children younger than 6 years with cystic fibrosis: the ISIS randomized controlled trial

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3824058

6 September 2017

Mucus clearance, MyD88-dependent and MyD88-independent immunity modulate lung susceptibility to spontaneous bacterial infection and inflammation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3824058

6 September 2017

Inhaled hypertonic saline in infants and toddlers with cystic fibrosis: short-term tolerability, adherence, and safety.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3824058

6 September 2017

Nebulized hypertonic saline decreases IL-8 in sputum of patients with cystic fibrosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3824058

6 September 2017

Airway mucus function and dysfunction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3824058

6 September 2017

Airway surface liquid volume regulation determines different airway phenotypes in liddle compared with betaENaC-overexpressing mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3824058

6 September 2017

Osmolytes and ion transport modulators: new strategies for airway surface rehydration.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3824058

6 September 2017

Mucus hypersecretion in asthma: causes and effects

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3824058

6 September 2017

Nebulized hypertonic saline solution for acute bronchiolitis in infants

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3824058

6 September 2017

Role of cilia, mucus, and airway surface liquid in mucociliary dysfunction: lessons from mouse models

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3824058

6 September 2017

Endpoints for clinical trials in young children with cystic fibrosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3824058

6 September 2017

Airway surface dehydration in cystic fibrosis: pathogenesis and therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3824058

6 September 2017

Regulation of mucin genes in chronic inflammatory airway diseases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3824058

6 September 2017

Glucocorticoids for acute viral bronchiolitis in infants and young children

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3824058

6 September 2017

The nature of small-airway obstruction in chronic obstructive pulmonary disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3824058

6 September 2017

Increased airway epithelial Na+ absorption produces cystic fibrosis-like lung disease in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3824058

6 September 2017

Evidence for periciliary liquid layer depletion, not abnormal ion composition, in the pathogenesis of cystic fibrosis airways disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3824058

6 September 2017

Effect of repeated sputum induction on cell counts in normal volunteers.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3824058

6 September 2017

Effect of increasing doses of hypertonic saline on mucociliary clearance in patients with cystic fibrosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3824058

6 September 2017

Effect of aerosolized recombinant human DNase on exacerbations of respiratory symptoms and on pulmonary function in patients with cystic fibrosis. The Pulmozyme Study Group

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3824058

6 September 2017

The amiloride-inhibitable Na+ conductance is reduced by the cystic fibrosis transmembrane conductance regulator in normal but not in cystic fibrosis airways.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3824058

14 September 2017

Hyperosmolarity-induced interleukin-8 expression in human bronchial epithelial cells through p38 mitogen-activated protein kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3824058

28 September 2017

SLC26A9-mediated chloride secretion prevents mucus obstruction in airway inflammation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3824058

26 June 2018

Allergic airway inflammation induces a pro-secretory epithelial ion transport phenotype in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3824058

26 June 2018

Long-term inhaled dry powder mannitol in cystic fibrosis: an international randomized study.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3824058

2 September 2018

Nebulised 7% hypertonic saline improves lung function and quality of life in bronchiectasis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3824058

2 September 2018

Bronchiectasis in infants and preschool children diagnosed with cystic fibrosis after newborn screening.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3824058

2 September 2018

Lung disease at diagnosis in infants with cystic fibrosis detected by newborn screening.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3824058

2 September 2018

Preventive but not late amiloride therapy reduces morbidity and mortality of lung disease in betaENaC-overexpressing mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3824058

2 September 2018

Development of chronic bronchitis and emphysema in beta-epithelial Na+ channel-overexpressing mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3824058

2 September 2018

Mucus clearance and lung function in cystic fibrosis with hypertonic saline

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3824058

2 September 2018

A controlled trial of long-term inhaled hypertonic saline in patients with cystic fibrosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3824058

2 September 2018

The CF salt controversy: in vivo observations and therapeutic approaches.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3824058

2 September 2018

Morphologic and functional scoring of cystic fibrosis lung disease using MRI

1 reference

https://api.crossref.org/works/10.1165%2FRCMB.2013-0050OC

21 January 2018

Repeated Sputum Inductions Induce a Transient Neutrophilic and Eosinophilic Response

1 reference

https://api.crossref.org/works/10.1165%2FRCMB.2013-0050OC

21 January 2018

Bronchodilators for bronchiolitis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3824058

20 October 2018

Exciting New Clinical Trials in Cystic Fibrosis

1 reference

https://api.crossref.org/works/10.1165%2FRCMB.2013-0050OC

21 January 2018

Hypertonic saline in treatment of pulmonary disease in cystic fibrosis

1 reference

https://api.crossref.org/works/10.1165%2FRCMB.2013-0050OC

21 January 2018

Abnormal Ion Permeation Through Cystic Fibrosis Respiratory Epithelium

1 reference

https://pubmed.ncbi.nlm.nih.gov/23590312

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vivo release of inflammatory mediators by hyperosmolar solutions

1 reference

https://pubmed.ncbi.nlm.nih.gov/23590312

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Biochemistry. Walking on solid ground

1 reference

https://pubmed.ncbi.nlm.nih.gov/23590312

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lung function is abnormal in 3-month-old infants with cystic fibrosis diagnosed by newborn screening

1 reference

https://pubmed.ncbi.nlm.nih.gov/23590312

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

High susceptibility for cystic fibrosis human airway gland cells to produce IL-8 through the I kappa B kinase alpha pathway in response to extracellular NaCl content

1 reference

https://pubmed.ncbi.nlm.nih.gov/23590312

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vivo monitoring of cystic fibrosis-like lung disease in mice by volumetric computed tomography

1 reference

https://pubmed.ncbi.nlm.nih.gov/23590312

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Early Cystic Fibrosis Lung Disease Detected by Bronchoalveolar Lavage and Lung Clearance Index

1 reference

https://pubmed.ncbi.nlm.nih.gov/23590312

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1165/RCMB.2013-0050OC

1 reference

Europe PubMed Central

19 August 2017

1 reference

Europe PubMed Central

19 August 2017

1 reference

Europe PubMed Central

19 August 2017

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