(Q37308689)

19 August 2017

Structurally simple, potent, Plasmodium selective farnesyltransferase inhibitors that arrest the growth of malaria parasites (English)

1 reference

19 August 2017

0 references

13

Michael Gelb

1 reference

19 August 2017

9

Frederick S Buckner

1 reference

19 August 2017

4

Kasey Rivas

1 reference

19 August 2017

11

Debopam Chakrabarti

1 reference

19 August 2017

5

Kohei Yokoyama

1 reference

19 August 2017

7

Steven Fletcher

1 reference

19 August 2017

Christopher L Cummings

series ordinal

8

object named as

Christopher G Cummings

1 reference

19 August 2017

3

Carrie Hornéy

1 reference

19 August 2017

12

Saïd M Sebti

1 reference

19 August 2017

14

Wesley C Van Voorhis

1 reference

19 August 2017

2

Sung-Youn Chang

1 reference

19 August 2017

10

Prakash R Pendyala

1 reference

19 August 2017

Matthew P Glenn

1

1 reference

19 August 2017

Erin E Pusateri

series ordinal

6

1 reference

19 August 2017

Andrew D Hamilton

series ordinal

15

1 reference

19 August 2017

language of work or name

English

0 references

publication date

1 September 2006

1 reference

Journal of Medicinal Chemistry

19 August 2017

1 reference

19 August 2017

49

1 reference

19 August 2017

5710-5727

1 reference

19 August 2017

19

1 reference

19 August 2017

New Antimalarial Drugs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2728208

Chemoresistance in falciparum malaria

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2728208

Antimalarial drug discovery: old and new approaches

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2728208

Protein farnesyl and N-myristoyl transferases: piggy-back medicinal chemistry targets for the development of antitrypanosomatid and antimalarial therapeutics.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2728208

Protein farnesyltransferase and protein prenylation in Plasmodium falciparum

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2728208

Inhibitors of protein farnesyltransferase as novel anticancer agents

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2728208

Medical need, scientific opportunity and the drive for antimalarial drugs

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2728208

The economic and social burden of malaria

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2728208

Farnesyltransferase and geranylgeranyltransferase I inhibitors and cancer therapy: lessons from mechanism and bench-to-bedside translational studies

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2728208

Peptidomimetic inhibitors of protein farnesyltransferase show potent antimalarial activity

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2728208

Discovery of (R)-7-cyano-2,3,4, 5-tetrahydro-1-(1H-imidazol-4-ylmethyl)-3- (phenylmethyl)-4-(2-thienylsulfonyl)-1H-1,4-benzodiazepine (BMS-214662), a farnesyltransferase inhibitor with potent preclinical antitumor activity

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2728208

Crystal structure of farnesyl protein transferase complexed with a CaaX peptide and farnesyl diphosphate analogue

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2728208

Development and validation of a genetic algorithm for flexible docking

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2728208

Correlation between oral drug absorption in humans and apparent drug permeability coefficients in human intestinal epithelial (Caco-2) cells

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2728208

Human malaria parasites in continuous culture

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2728208

MDCK (Madin-Darby canine kidney) cells: A tool for membrane permeability screening

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2728208

Protein prenyl transferase activities of Plasmodium falciparum.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2728208

Structurally simple farnesyltransferase inhibitors arrest the growth of malaria parasites.

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2728208

Protein farnesyltransferase inhibitors exhibit potent antimalarial activity

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2728208

Resistance to a protein farnesyltransferase inhibitor in Plasmodium falciparum

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2728208

Farnesyltransferase inhibitors inhibit the growth of malaria parasites in vitro and in vivo.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2728208

Partitioning between N-dealkylation and N-oxygenation in the oxidation of N,N-dialkylarylamines catalyzed by cytochrome P450 2B1

2 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16970397

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Fluoro-Olefins as Peptidomimetic Inhibitors of Dipeptidyl Peptidases

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16970397

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1021/JM060081V

1 reference

19 August 2017

1 reference

19 August 2017

1 reference