(Q37311388)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18959738%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

review article

1 reference

title

Gonadotropin-releasing hormone: GnRH receptor signaling in extrapituitary tissues (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18959738%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18959738%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

author name string

Alice S T Wong

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18959738%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

language of work or name

English

0 references

publication date

1 November 2008

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18959738%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18959738%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

volume

275

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18959738%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

issue

22

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18959738%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

page(s)

5479-5495

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18959738%20AND%20SRC:MED&resulttype=core&format=json

A second isoform of gonadotropin-releasing hormone is present in the brain of human and rodents.

25 December 2019

cites work

1 reference

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Second gene for gonadotropin-releasing hormone in humans

21 January 2018

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Relative Effect of Gonadotropin-Releasing Hormone (GnRH)-I and GnRH-II on Gonadotropin Release

21 January 2018

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Emerging functions of gonadotropin-releasing hormone II in mammalian physiology and behaviour

21 January 2018

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Immunolocalization of gonadotropin-releasing hormone (GnRH)-I, GnRH-II, and type I GnRH receptor during follicular development in the human ovary.

21 January 2018

1 reference

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Detection of gonadotropin-releasing hormone receptor and its mRNA in primary human epithelial ovarian cancers

21 January 2018

1 reference

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Gonadotropin-releasing hormone promotes ovarian cancer cell invasiveness through c-Jun NH2-terminal kinase-mediated activation of matrix metalloproteinase (MMP)-2 and MMP-9.

21 January 2018

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Differential role of gonadotropin-releasing hormone on human ovarian epithelial cancer cell invasion.

21 January 2018

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Presence of gonadotropin-releasing hormone receptor and its messenger ribonucleic acid in endometrial carcinoma and endometrium

21 January 2018

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GnRH mRNA and protein expression in human preimplantation embryos.

21 January 2018

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Nucleotide sequence analyses predict that human pituitary and human placental gonadotropin-releasing hormone receptors have identical primary structures

21 January 2018

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The genes for gonadotropin-releasing hormone and its receptor are expressed in human breast with fibrocystic disease and cancer.

21 January 2018

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Immunohistochemical expression of gonadotropin releasing hormone receptor in human breast carcinoma

21 January 2018

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Gonadotropin-releasing hormone receptor expression in the human prostate

21 January 2018

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The nucleotide sequences of human GnRH receptors in breast and ovarian tumors are identical with that found in pituitary

21 January 2018

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Direct effects of luteinizing hormone-releasing hormone agonists and antagonists on MCF-7 mammary cancer cells

21 January 2018

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The effects of gonadotrophin releasing hormone analogues in prostate cancer are mediated through specific tumour receptors

21 January 2018

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Specific low affinity binding sites for gonadotropin-releasing hormone in human endometrial carcinomata

21 January 2018

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Lupron retards proliferation of ovarian epithelial tumor cells cultured in serum-free medium

21 January 2018

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Expression of receptors for luteinizing hormone-releasing hormone in human ovarian and endometrial cancers: frequency, autoregulation, and correlation with direct antiproliferative activity of luteinizing hormone-releasing hormone analogues

21 January 2018

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Effects of GnRH analogs on six ovarian cancer cell lines in culture

21 January 2018

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Antiproliferative effects of the GnRH antagonist cetrorelix and of GnRH-II on human endometrial and ovarian cancer cells are not mediated through the GnRH type I receptor

21 January 2018

1 reference

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Inhibition of human epithelial ovarian cancer cell growth in vitro by agonistic and antagonistic analogues of luteinizing hormone-releasing hormone

21 January 2018

1 reference

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Inhibition of growth of OV-1063 human epithelial ovarian cancer xenografts in nude mice by treatment with luteinizing hormone-releasing hormone antagonist SB-75.

21 January 2018

1 reference

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Luteinizing hormone-releasing hormone analogs: their impact on the control of tumorigenesis

21 January 2018

1 reference

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Direct growth inhibition of human endometrial cancer cells by the gonadotropin-releasing hormone antagonist SB-75: role of apoptosis

21 January 2018

1 reference

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Antiproliferative effects of luteinizing hormone-releasing hormone agonists on the human prostatic cancer cell line LNCaP

21 January 2018

1 reference

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Inhibition of growth of androgen-independent DU-145 prostate cancer in vivo by luteinising hormone-releasing hormone antagonist Cetrorelix and bombesin antagonists RC-3940-II and RC-3950-II.

21 January 2018

1 reference

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Gonadotropin-releasing hormone induces apoptosis of prostate cancer cells: role of c-Jun NH2-terminal kinase, protein kinase B, and extracellular signal-regulated kinase pathways

21 January 2018

1 reference

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Proliferation of TSU-Pr1, a human prostatic carcinoma cell line is stimulated by gonadotropin-releasing hormone

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2008.06677.X

Human type II GnRH receptor mediates effects of GnRH on cell proliferation

21 January 2018

1 reference

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Analogs of GnRH-I and GnRH-II inhibit epidermal growth factor-induced signal transduction and resensitize resistant human breast cancer cells to 4OH-tamoxifen

21 January 2018

1 reference

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Inhibition of growth of human mammary tumor cells by potent antagonists of luteinizing hormone-releasing hormone

21 January 2018

1 reference

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Independent regulation of matrix metalloproteinase-9, tissue inhibitor of metalloproteinase-1 (TIMP-1), and TIMP-3 in human endometrial stromal cells by gonadotropin-releasing hormone: implications in early human implantation

21 January 2018

1 reference

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The effects of gonadotropin-releasing hormone (GnRH) I and GnRH II on the urokinase-type plasminogen activator/plasminogen activator inhibitor system in human extravillous cytotrophoblasts in vitro

21 January 2018

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Inhibitory activity of luteinizing hormone-releasing hormone on tumor growth and progression.

21 January 2018

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Evidence that prostate gonadotropin-releasing hormone receptors mediate an anti-tumourigenic response to analogue therapy in hormone refractory prostate cancer.

21 January 2018

1 reference

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Gonadotropin-releasing hormone induces actin cytoskeleton remodeling and affects cell migration in a cell-type-specific manner in TSU-Pr1 and DU145 cells

21 January 2018

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GnRH analogs reduce invasiveness of human breast cancer cells

21 January 2018

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Regulation of ovarian angiogenesis and apoptosis by GnRH-I analogs

21 January 2018

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Clinical response, vascular change, and angiogenesis in gonadotropin-releasing hormone analogue-treated women with uterine myomas

21 January 2018

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Gonadotropin-releasing hormone in apoptosis of prostate cancer cells

21 January 2018

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Type II gonadotropin-releasing hormone stimulates p38 mitogen-activated protein kinase and apoptosis in ovarian cancer cells.

21 January 2018

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Roles of Src and epidermal growth factor receptor transactivation in transient and sustained ERK1/2 responses to gonadotropin-releasing hormone receptor activation

21 January 2018

1 reference

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Specificity of receptor tyrosine kinase signaling: transient versus sustained extracellular signal-regulated kinase activation

21 January 2018

1 reference

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Identification of the mechanisms regulating the differential activation of the mapk cascade by epidermal growth factor and nerve growth factor in PC12 cells

21 January 2018

1 reference

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Fidelity and spatio-temporal control in MAP kinase (ERKs) signalling

21 January 2018

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Regulation of matrix metalloproteinases: an overview

21 January 2018

1 reference

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Dependence of gonadotropin-releasing hormone-induced neuronal MAPK signaling on epidermal growth factor receptor transactivation

21 January 2018

1 reference

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Matrix metalloproteinases 2 and 9 mediate epidermal growth factor receptor transactivation by gonadotropin-releasing hormone

21 January 2018

1 reference

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Antiproliferative signaling of luteinizing hormone-releasing hormone in human endometrial and ovarian cancer cells through G protein alpha(I)-mediated activation of phosphotyrosine phosphatase

21 January 2018

1 reference

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Luteinizing hormone-releasing hormone agonists interfere with the mitogenic activity of the insulin-like growth factor system in androgen-independent prostate cancer cells

21 January 2018

1 reference

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Molecular mechanisms involved in GnRH analogue-related apoptosis for uterine leiomyomas

21 January 2018

1 reference

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Role of EGF receptor transactivation in phosphoinositide 3-kinase-dependent activation of MAP kinase by GPCRs

21 January 2018

1 reference

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Tumor necrosis factor-alpha-induced interleukin-8 (IL-8) expression in endometriotic stromal cells, probably through nuclear factor-kappa B activation: gonadotropin-releasing hormone agonist treatment reduced IL-8 expression

21 January 2018

1 reference

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Gonadotropin-releasing hormone functionally antagonizes testosterone activation of the human androgen receptor in prostate cells through focal adhesion complexes involving Hic-5.

21 January 2018

1 reference

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Studies of gonadotropin-releasing hormone (GnRH) action using GnRH receptor-expressing pituitary cell lines

21 January 2018

1 reference

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An agonist-induced switch in G protein coupling of the gonadotropin-releasing hormone receptor regulates pulsatile neuropeptide secretion.

21 January 2018

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Involvement of both G(q/11) and G(s) proteins in gonadotropin-releasing hormone receptor-mediated signaling in L beta T2 cells

21 January 2018

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Regulation of Ca2+-sensitive adenylyl cyclase in gonadotropin-releasing hormone neurons

21 January 2018

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Gonadotropin-releasing hormone receptor initiates multiple signaling pathways by exclusively coupling to G(q/11) proteins.

21 January 2018

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New roles for G-protein beta gamma-dimers in transmembrane signalling.

21 January 2018

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Hormonal stimulation of adenylyl cyclase through Gi-protein beta gamma subunits

21 January 2018

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Type-specific regulation of adenylyl cyclase by G protein beta gamma subunits

21 January 2018

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A mechanism for the differential regulation of gonadotropin subunit gene expression by gonadotropin-releasing hormone.

21 January 2018

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Mutations remote from the human gonadotropin-releasing hormone (GnRH) receptor-binding sites specifically increase binding affinity for GnRH II but not GnRH I: evidence for ligand-selective, receptor-active conformations.

21 January 2018

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Structural determinants for ligand-receptor conformational selection in a peptide G protein-coupled receptor.

21 January 2018

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Identification of a novel pituitary-specific chicken gonadotropin-releasing hormone receptor and its splice variants

21 January 2018

1 reference

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Structure of the mouse gonadotropin-releasing hormone receptor gene: variant transcripts generated by alternative processing

21 January 2018

1 reference

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Tissue-specific pattern of variant transcripts of the human gonadotropin-releasing hormone receptor gene

21 January 2018

1 reference

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Expression of gonadotropin-releasing hormone (GnRH) and GnRH receptor mRNA in prostate cancer cells and effect of GnRH on the proliferation of prostate cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2008.06677.X

Biological differences among MCF-7 human breast cancer cell lines from different laboratories

21 January 2018

1 reference

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Tumor promoting properties of the ETS protein MEF in ovarian cancer.

21 January 2018

1 reference

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Immortalized and tumorigenic adult human prostatic epithelial cell lines: characteristics and applications Part 2. Tumorigenic cell lines

21 January 2018

1 reference

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Successful immortalization of endometrial glandular cells with normal structural and functional characteristics

21 January 2018

1 reference

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Isolation of a human prostate carcinoma cell line (DU 145)

21 January 2018

1 reference

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Association of increased basement membrane invasiveness with absence of estrogen receptor and expression of vimentin in human breast cancer cell lines

21 January 2018

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Establishment of an immortalised human ovarian surface epithelial cell line without chromosomal instability

21 January 2018

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A novel mammalian receptor for the evolutionarily conserved type II GnRH

21 January 2018

1 reference

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Two gonadotropin-releasing hormone receptor subtypes with distinct ligand selectivity and differential distribution in brain and pituitary in the goldfish (Carassius auratus)

21 January 2018

1 reference

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A gonadotropin-releasing hormone (GnRH) receptor specific for GnRH II in primates

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2008.06677.X

Minireview: GnRH and GnRH Receptor Genes in the Human Genome

21 January 2018

1 reference

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GnRH-II receptor-like antigenicity in human placenta and in cancers of the human reproductive organs

21 January 2018

1 reference

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A transcriptionally active human type II gonadotropin-releasing hormone receptor gene homolog overlaps two genes in the antisense orientation on chromosome 1q.12

21 January 2018

1 reference

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Mammalian type I gonadotropin-releasing hormone receptors undergo slow, constitutive, agonist-independent internalization

21 January 2018

1 reference

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Signaling and antiproliferative effects of type I and II gonadotropin-releasing hormone receptors in breast cancer cells

21 January 2018

1 reference

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Evidence that gonadotropin-releasing hormone (GnRH) II stimulates luteinizing hormone and follicle-stimulating hormone secretion from monkey pituitary cultures by activating the GnRH I receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2008.06677.X

Evidence that the type-2 gonadotrophin-releasing hormone (GnRH) receptor mediates the behavioural effects of GnRH-II on feeding and reproduction in musk shrews.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2008.06677.X

Type II gonadotropin-releasing hormone receptor transcripts in human sperm

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2008.06677.X

Differential effects of gonadotropin-releasing hormone (GnRH)-I and GnRH-II on prostate cancer cell signaling and death

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2008.06677.X

Inhibition of Gonadotropin-Releasing Hormone Receptor Signaling by Expression of a Splice Variant of the Human Receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2008.06677.X

Expression of Gonadotropin-Releasing Hormone II (GnRH-II) Receptor in Human Endometrial and Ovarian Cancer Cells and Effects of GnRH-II on Tumor Cell Proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2008.06677.X

c-Src is activated by the epidermal growth factor receptor in a pathway that mediates JNK and ERK activation by gonadotropin-releasing hormone in COS7 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2008.06677.X

Gonadotropin-Releasing Hormone (GnRH)-Binding Sites in Human Breast Cancer Cell Lines and Inhibitory Effects of GnRH Antagonists*

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2008.06677.X

Growth of human breast cancer cells inhibited by a luteinizing hormone-releasing hormone agonist

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2008.06677.X