(Q52564801)

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Mutations remote from the human gonadotropin-releasing hormone (GnRH) receptor-binding sites specifically increase binding affinity for GnRH II but not GnRH I: evidence for ligand-selective, receptor-active conformations.

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1 reference

Europe PubMed Central

3 May 2018

http://europepmc.org/abstract/MED/15967801

Mutations remote from the human gonadotropin-releasing hormone (GnRH) receptor-binding sites specifically increase binding affinity for GnRH II but not GnRH I: evidence for ligand-selective, receptor-active conformations. (English)

1 reference

Europe PubMed Central

3 May 2018

http://europepmc.org/abstract/MED/15967801

Robert P. Millar

5

1 reference

Europe PubMed Central

3 May 2018

http://europepmc.org/abstract/MED/15967801

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Zhi-Liang Lu

1

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Ryan Gallagher

2

1 reference

Europe PubMed Central

3 May 2018

http://europepmc.org/abstract/MED/15967801

Robin Sellar

3

1 reference

Europe PubMed Central

3 May 2018

http://europepmc.org/abstract/MED/15967801

Marla Coetsee

4

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Europe PubMed Central

3 May 2018

http://europepmc.org/abstract/MED/15967801

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publication date

20 June 2005

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Europe PubMed Central

3 May 2018

http://europepmc.org/abstract/MED/15967801

Journal of Biological Chemistry

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Europe PubMed Central

3 May 2018

http://europepmc.org/abstract/MED/15967801

280

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Europe PubMed Central

3 May 2018

http://europepmc.org/abstract/MED/15967801

33

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Europe PubMed Central

3 May 2018

http://europepmc.org/abstract/MED/15967801

29796-29803

1 reference

Europe PubMed Central

3 May 2018

http://europepmc.org/abstract/MED/15967801

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Dominant-negative activity of an alpha(1B)-adrenergic receptor signal-inactivating point mutation

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Mutation of a single TMVI residue, Phe(282), in the beta(2)-adrenergic receptor results in structurally distinct activated receptor conformations

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Conserved helix 7 tyrosine acts as a multistate conformational switch in the 5HT2C receptor. Identification of a novel "locked-on" phenotype and double revertant mutations.

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A single amino acid substitution in transmembrane helix VI results in overexpression of the human GnRH receptor

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A chicken gonadotropin-releasing hormone receptor that confers agonist activity to mammalian antagonists. Identification of D-Lys(6) in the ligand and extracellular loop two of the receptor as determinants

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Transmembrane domains 4 and 7 of the M(1) muscarinic acetylcholine receptor are critical for ligand binding and the receptor activation switch

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Identifiers

10.1074/JBC.M413520200

1 reference

Europe PubMed Central

3 May 2018

http://europepmc.org/abstract/MED/15967801

1 reference

Europe PubMed Central

3 May 2018

http://europepmc.org/abstract/MED/15967801

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