(Q40416265)

20 September 2017

title

Role of EGF receptor transactivation in phosphoinositide 3-kinase-dependent activation of MAP kinase by GPCRs (English)

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G protein-coupled receptor

20 September 2017

main subject

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author name string

Bukhtiar H Shah

1

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20 September 2017

Adrienne Neithardt

2

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20 September 2017

David B Chu

3

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20 September 2017

Farzana B Shah

4

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20 September 2017

Kevin J Catt

5

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20 September 2017

publication date

1 January 2006

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Journal of Cellular Physiology

20 September 2017

published in

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20 September 2017

volume

206

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20 September 2017

issue

1

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20 September 2017

page(s)

47-57

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Class I phosphoinositide 3-kinases.

20 September 2017

cites work

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LY294002, an inhibitor of phosphoinositide 3-kinase given into rat hippocampus impairs acquisition, consolidation and retrieval of memory for one-trial step-down inhibitory avoidance

21 January 2018

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Genetic models meet trophic mechanisms: EGF family members are gliatrophins in Drosophila

21 January 2018

1 reference

Advances in protein kinase B signalling: AKTion on multiple fronts

21 January 2018

1 reference

Neuregulin and ErbB receptor signaling pathways in the nervous system

21 January 2018

1 reference

The phosphoinositide 3-kinase pathway

21 January 2018

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EGF receptor transactivation mediates ANG II-stimulated mitogenesis in intestinal epithelial cells through the PI3-kinase/Akt/mTOR/p70S6K1 signaling pathway

21 January 2018

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PI3K-FRAP/mTOR pathway is critical for hepatocyte proliferation whereas MEK/ERK supports both proliferation and survival

21 January 2018

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The dark side of Ras: regulation of apoptosis

21 January 2018

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Metalloprotease-dependent ErbB ligand shedding in mediating EGFR transactivation and vascular remodelling

21 January 2018

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Gene-targeting reveals physiological roles and complex regulation of the phosphoinositide 3-kinases

21 January 2018

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Epidermal growth factor protects epithelial cells against Fas-induced apoptosis. Requirement for Akt activation

21 January 2018

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Phosphatidylinositol 3-kinase is an early intermediate in the G beta gamma-mediated mitogen-activated protein kinase signaling pathway

21 January 2018

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Differential PI 3-kinase dependence of early and late phases of recycling of the internalized AT1 angiotensin receptor

21 January 2018

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Epidermal growth factor receptor: mechanisms of activation and signalling.

21 January 2018

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c-Src is activated by the epidermal growth factor receptor in a pathway that mediates JNK and ERK activation by gonadotropin-releasing hormone in COS7 cells

21 January 2018

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An epidermal growth factor receptor/Gab1 signaling pathway is required for activation of phosphoinositide 3-kinase by lysophosphatidic acid.

21 January 2018

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Src homology 3 binding sites in the P2Y2 nucleotide receptor interact with Src and regulate activities of Src, proline-rich tyrosine kinase 2, and growth factor receptors

21 January 2018

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Convergent signal transduction pathways controlling cardiomyocyte survival and function: the role of PI 3-kinase and Akt.

21 January 2018

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Gonadotropin-releasing hormone receptors

21 January 2018

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PDK1, the master regulator of AGC kinase signal transduction

21 January 2018

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Agonist-specific transactivation of phosphoinositide 3-kinase signaling pathway mediated by the dopamine D2 receptor

21 January 2018

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Functions of PI 3-kinase in development of the nervous system

21 January 2018

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Cell signaling by receptor tyrosine kinases

21 January 2018

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Calcium-independent activation of extracellularly regulated kinases 1 and 2 by angiotensin II in hepatic C9 cells: roles of protein kinase Cdelta, Src/proline-rich tyrosine kinase 2, and epidermal growth receptor trans-activation

21 January 2018

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A central role of EGF receptor transactivation in angiotensin II -induced cardiac hypertrophy

21 January 2018

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GPCR-mediated transactivation of RTKs in the CNS: mechanisms and consequences

21 January 2018

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Dependence of gonadotropin-releasing hormone-induced neuronal MAPK signaling on epidermal growth factor receptor transactivation

21 January 2018

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Neuropeptide-induced transactivation of a neuronal epidermal growth factor receptor is mediated by metalloprotease-dependent formation of heparin-binding epidermal growth factor

21 January 2018

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Differential pathways of angiotensin II-induced extracellularly regulated kinase 1/2 phosphorylation in specific cell types: role of heparin-binding epidermal growth factor

21 January 2018

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PYK2 links G(q)alpha and G(13)alpha signaling to NF-kappa B activation.

21 January 2018

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Akt/protein kinase B promotes organ growth in transgenic mice

21 January 2018

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Transactivation joins multiple tracks to the ERK/MAPK cascade

21 January 2018

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Phosphoinositide 3-kinases as targets for therapeutic intervention

21 January 2018

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Phosphoinositide 3-kinases in lysophosphatidic acid signaling: regulation and cross-talk with the Ras/mitogen-activated protein kinase pathway.

21 January 2018

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ERK negatively regulates the epidermal growth factor-mediated interaction of Gab1 and the phosphatidylinositol 3-kinase

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/JCP.20423

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20 September 2017

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