(Q37352061)

19 August 2017

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title

Commonalities in the genetics of Alzheimer's disease and Parkinson's disease (English)

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19 August 2017

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1 reference

Edna Grünblatt

1

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publication date

1 December 2008

1 reference

Expert Review of Neurotherapeutics: a key contribution to decision making in the treatment of neurologic and neuropsychiatric disorders

19 August 2017

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19 August 2017

8

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19 August 2017

12

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19 August 2017

1865-1877

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Distribution of major health risks: findings from the Global Burden of Disease study

19 August 2017

1 reference

https://api.crossref.org/works/10.1586%2F14737175.8.12.1865

The global burden of disease study: implications for neurology

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.8.12.1865

The two faces of protein misfolding: gain- and loss-of-function in neurodegenerative diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.8.12.1865

Alzheimer's disease and Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.8.12.1865

An English translation of Alzheimer's 1907 paper, "Uber eine eigenartige Erkankung der Hirnrinde".

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.8.12.1865

Parkinsonism: onset, progression, and mortality

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.8.12.1865

Parkinson disease, dementia, and Alzheimer disease: clinicopathological correlations.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.8.12.1865

Dementia in idiopathic Parkinson's disease. A neuropathological study of 32 cases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.8.12.1865

The relationship between oxidative/nitrative stress and pathological inclusions in Alzheimer's and Parkinson's diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.8.12.1865

Environmental risk factors in Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.8.12.1865

Risk factors for Alzheimer dementia in a community-based birth cohort at the age of 75 years

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.8.12.1865

Biomarkers for the early detection of Parkinson's and Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.8.12.1865

Neuropsychological and perceptual defects in Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.8.12.1865

Is late onset depression a prodrome to dementia?

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.8.12.1865

Olfaction in neurodegenerative disorder

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.8.12.1865

The olfactory vector hypothesis of neurodegenerative disease: is it viable?

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.8.12.1865

Genes and the environment in neurodegeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.8.12.1865

Parkinson's disease risk factors: genetic, environmental, or both?

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.8.12.1865

Interaction between genes and environment in neurodegenerative diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.8.12.1865

Hormone replacement therapy and incidence of Alzheimer disease in older women: the Cache County Study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.8.12.1865

Alzheimer disease--no target for statin treatment. A mini review

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.8.12.1865

Cardiovascular Risk Factors for Alzheimer's Disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.8.12.1865

The metabolic syndrome and Alzheimer disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.8.12.1865

Genotype and phenotype in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.8.12.1865

Genetics of Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.8.12.1865

The proteasome in Alzheimer's disease and Parkinson's disease: lessons from ubiquitin B+1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.8.12.1865

Genetic heterogeneity of Alzheimer's disease: complexity and advances

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.8.12.1865

Presence of an APOE4 allele results in significantly earlier onset of Parkinson's disease and a higher risk with dementia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.8.12.1865

Etiology and pathophysiology of frontotemporal dementia, Parkinson disease and Alzheimer disease: lessons from genetic studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.8.12.1865

Haplotypes and gene expression implicate the MAPT region for Parkinson disease: the GenePD Study

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.8.12.1865

Genetics of Parkinson disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.8.12.1865

Genome-wide analysis of the parkinsonism-dementia complex of Guam

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.8.12.1865

Genome scan on Swedish Alzheimer's disease families.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.8.12.1865

Genome-Wide Association Studies in Alzheimer Disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.8.12.1865

Genome-wide genotyping in Parkinson's disease and neurologically normal controls: first stage analysis and public release of data

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.8.12.1865

Discerning the ancestry of European Americans in genetic association studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.8.12.1865

Linkage disequilibrium-based quality control for large-scale genetic studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.8.12.1865

HapMap filter 1.0: a tool to preprocess the HapMap genotypic data for association studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.8.12.1865

Use of cDNA microarray in the search for molecular markers involved in the onset of Alzheimer's disease dementia

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.8.12.1865

Gene expression profiling of 12633 genes in Alzheimer hippocampal CA1: transcription and neurotrophic factor down-regulation and up-regulation of apoptotic and pro-inflammatory signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.8.12.1865

Defects in expression of genes related to synaptic vesicle trafficking in frontal cortex of Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.8.12.1865

Cell type-specific gene expression of midbrain dopaminergic neurons reveals molecules involved in their vulnerability and protection

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.8.12.1865

Expression profiling of substantia nigra in Parkinson disease, progressive supranuclear palsy, and frontotemporal dementia with parkinsonism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.8.12.1865

Multiregional gene expression profiling identifies MRPS6 as a possible candidate gene for Parkinson's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.8.12.1865

Glutathione S-transferase omega-1 modifies age-at-onset of Alzheimer disease and Parkinson disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.8.12.1865

Revealing the role of glutathione S-transferase omega in age-at-onset of Alzheimer and Parkinson diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.8.12.1865

Association of GST M1 null polymorphism with Parkinson's disease in a Chilean population with a strong Amerindian genetic component.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.8.12.1865

Association of A313 G polymorphism (GSTP1*B) in the glutathione-S-transferase P1 gene with sporadic Parkinson's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.8.12.1865

Alzheimer Disease and Oxidative Stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.8.12.1865

Oxidative stress and inflammation in Parkinson's disease: is there a causal link?

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.8.12.1865

Excess brain protein oxidation and enzyme dysfunction in normal aging and in Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.8.12.1865

Oxidative RNA damage and neurodegeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.8.12.1865

Epigenetic targets of HDAC inhibition in neurodegenerative and psychiatric disorders.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.8.12.1865

Neurodegeneration in the age of molecular biology

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.8.12.1865

Direct quantification of CSF alpha-synuclein by ELISA and first cross-sectional study in patients with neurodegeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.8.12.1865

Prevention and promotion effects of apolipoprotein E4 on amylin aggregation

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.8.12.1865

Blocking the apolipoprotein E/amyloid-beta interaction as a potential therapeutic approach for Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.8.12.1865

Effect of truncated-ApoE4 overexpression on tau phosphorylation in cultured N2a cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.8.12.1865

Expression of human apolipoprotein E4 in neurons causes hyperphosphorylation of protein tau in the brains of transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.8.12.1865

Tau hyperphosphorylation in apolipoprotein E-deficient and control mice after closed head injury.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.8.12.1865

A molecular pathway of neurodegeneration linking alpha-synuclein to ApoE and Abeta peptides.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.8.12.1865

Role of complement in neurodegeneration and neuroinflammation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.8.12.1865

Peripheral inflammatory cytokines as biomarkers in Alzheimer's disease and mild cognitive impairment

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.8.12.1865

Free radicals in Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.8.12.1865

Neuronal death and survival under oxidative stress in Alzheimer and Parkinson diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.8.12.1865

Degeneration of neuronal cells due to oxidative stress--microglial contribution

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.8.12.1865

Reduced brain antioxidant capacity in rat models of betacytotoxic-induced experimental sporadic Alzheimer's disease and diabetes mellitus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.8.12.1865

Reduced antioxidant enzyme activity in brains of mice transgenic for human presenilin-1 with single or multiple mutations.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.8.12.1865

Glial heme oxygenase-1 expression in Alzheimer disease and mild cognitive impairment

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.8.12.1865

Correlations of glutathione peroxidase activity with memory impairment in adults with Down syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.8.12.1865

Crosslinking of alpha-synuclein by advanced glycation endproducts--an early pathophysiological step in Lewy body formation?

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.8.12.1865

Increased dopamine turnover after partial loss of dopaminergic neurons: compensation or toxicity?

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.8.12.1865

Neuroprotective strategies in Parkinson's disease : an update on progress

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.8.12.1865

Interrater reliability in the neuropathologic diagnosis of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.8.12.1865

Clinicopathological analysis of dementia disorders in the elderly.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.8.12.1865

Combined biomarkers for early Alzheimer disease diagnosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.8.12.1865

Cerebrospinal fluid biomarkers for diagnosis of Alzheimer's disease: Beta-amyloid(1-42), tau, phospho-tau-181 and total protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.8.12.1865

Longitudinal stability of CSF biomarkers in Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.8.12.1865

Increased cerebrospinal fluid cAMP levels in Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.8.12.1865

Novel panel of cerebrospinal fluid biomarkers for the prediction of progression to Alzheimer dementia in patients with mild cognitive impairment

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.8.12.1865

An aberrant protein complex in CSF as a biomarker of Alzheimer disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.8.12.1865

Biomarkers of neurodegeneration for diagnosis and monitoring therapeutics

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.8.12.1865

CSF multianalyte profile distinguishes Alzheimer and Parkinson diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.8.12.1865

Biomarkers for early diagnosis of Alzheimer disease: 'ALZheimer ASsociated gene'--a new blood biomarker?

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.8.12.1865

Peripheral inflammatory biomarkers and risk of Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.8.12.1865

Blood-based neurochemical diagnosis of vascular dementia: a pilot study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.8.12.1865

Evaluation of heme oxygenase-1 as a systemic biological marker of sporadic AD.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.8.12.1865

Proteome-based plasma biomarkers for Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.8.12.1865

Proteomics of Alzheimer's disease: understanding mechanisms and seeking biomarkers

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.8.12.1865

Blood-based proteomics for personalized medicine: examples from neurodegenerative disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.8.12.1865

Classification and prediction of clinical Alzheimer's diagnosis based on plasma signaling proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.8.12.1865

Oxidative stress related markers in the "VITA" and the centenarian projects.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.8.12.1865

Transcriptional profiling of Alzheimer blood mononuclear cells by microarray

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.8.12.1865

Gene expression profile analysis of lymphocytes from Alzheimer's patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.8.12.1865

Reduced Glucocorticoid Receptor alpha Expression in Mood Disorder Patients and First-Degree Relatives.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.8.12.1865

Lymphocytes as a neural probe: potential for studying psychiatric disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.8.12.1865

Transcriptional profiling of peripheral blood cells in clinical pharmacogenomic studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.8.12.1865

Decreased NURR1 gene expression in patients with Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.8.12.1865

Molecular markers of early Parkinson's disease based on gene expression in blood

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.8.12.1865

Evaluating the comparability of gene expression in blood and brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.8.12.1865

Complex disease-associated pharmacogenetics: drug efficacy, drug safety, and confirmation of a pathogenetic hypothesis (Alzheimer's disease).

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.8.12.1865

Identification of the genetic basis for complex disorders by use of pooling-based genomewide single-nucleotide-polymorphism association studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.8.12.1865

Meta-analysis in genome-wide association datasets: strategies and application in Parkinson disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.8.12.1865

Evidence for novel susceptibility genes for late-onset Alzheimer's disease from a genome-wide association study of putative functional variants

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.8.12.1865

A genome wide linkage disequilibrium screen in Parkinson’s disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.8.12.1865

10.1586/14737175.8.12.1865

21 January 2018

Identifiers

DOI

1 reference

19 August 2017

1 reference

PubMed ID

19086884