(Q37362072)

English

Suppression of activation and costimulatory signaling in splenic CD4+ T cells after trauma-hemorrhage reduces T-cell function: a mechanism of post-traumatic immune suppression

scientific article published on 03 September 2009

In more languages

Statements

scholarly article

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

Suppression of activation and costimulatory signaling in splenic CD4+ T cells after trauma-hemorrhage reduces T-cell function: a mechanism of post-traumatic immune suppression (English)

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

Irshad H. Chaudry

8

object named as

Irshad H Chaudry

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

author name string

Chi-Hsun Hsieh

1

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

Jun-Te Hsu

2

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

Ya-Ching Hsieh

3

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

Michael Frink

4

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

Raghavan Raju

5

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

William J Hubbard

6

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

Kirby I Bland

7

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

language of work or name

0 references

publication date

3 September 2009

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

The American Journal of Pathology

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

175

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

4

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

1504-1514

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

Mechanism of the salutary effects of estrogen on kupffer cell phagocytic capacity following trauma-hemorrhage: pivotal role of Akt activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2751547

9 September 2017

Phenotypic classification of human CD4+ T cell subsets and their differentiation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2751547

9 September 2017

CTLA-4 trafficking and surface expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2751547

9 September 2017

G protein-coupled receptor 30-dependent protein kinase A pathway is critical in nongenomic effects of estrogen in attenuating liver injury after trauma-hemorrhage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2751547

9 September 2017

Cell-specific expression and pathway analyses reveal alterations in trauma-related human T cell and monocyte pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2751547

9 September 2017

Kupffer cells and their mediators: the culprits in producing distant organ damage after trauma-hemorrhage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2751547

9 September 2017

CTLA-4 and PD-1 receptors inhibit T-cell activation by distinct mechanisms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2751547

9 September 2017

Sex differences in the myocardial inflammatory response to acute injury

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2751547

9 September 2017

Central memory and effector memory T cell subsets: function, generation, and maintenance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2751547

9 September 2017

The PI-3 kinase/Akt pathway and T cell activation: pleiotropic pathways downstream of PIP3

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2751547

9 September 2017

CD28 function: a balance of costimulatory and regulatory signals

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2751547

9 September 2017

The B7 family of ligands and its receptors: new pathways for costimulation and inhibition of immune responses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2751547

9 September 2017

Activation and inhibition of lymphocytes by costimulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2751547

9 September 2017

Akt provides the CD28 costimulatory signal for up-regulation of IL-2 and IFN-gamma but not TH2 cytokines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2751547

9 September 2017

Signaling pathways mediating insulin-stimulated glucose transport

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2751547

9 September 2017

Protein kinase B regulates T lymphocyte survival, nuclear factor kappaB activation, and Bcl-X(L) levels in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2751547

9 September 2017

Molecular basis of T cell inactivation by CTLA-4

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2751547

9 September 2017

A role for phosphoinositide 3-kinase in the completion of macropinocytosis and phagocytosis by macrophages

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2751547

9 September 2017

CD28/B7 system of T cell costimulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2751547

9 September 2017

Akt maintains cell size and survival by increasing mTOR-dependent nutrient uptake

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2751547

14 September 2017

TLR4 regulates Kupffer cell chemokine production, systemic inflammation and lung neutrophil infiltration following trauma-hemorrhage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2751547

14 September 2017

Pre-activation of T lymphocytes by low dose of concanavalin A aggravates toll-like receptor-3 ligand-induced NK cell-mediated liver injury

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2751547

14 September 2017

The CD28 and CTLA-4 receptors associate with the serine/threonine phosphatase PP2A.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2751547

28 September 2017

The IL-2 receptor promotes lymphocyte proliferation and induction of the c-myc, bcl-2, and bcl-x genes through the trans-activation domain of Stat5.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2751547

28 September 2017

Ligation of the T cell co-stimulatory receptor CD28 activates the serine-threonine protein kinase protein kinase B.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2751547

28 September 2017

Downregulation of T helper type 1 immune response and altered pro-inflammatory and anti-inflammatory T cell cytokine balance following conventional but not laparoscopic surgery

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2751547

26 June 2018

Posttraumatic lymphocyte response: a comparison between peripheral blood T cells and tissue T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2751547

26 June 2018

42 Lymphocytes as resting cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2751547

26 June 2018

Protection from graft-versus-host disease with a novel B7 binding site-specific mouse anti-mouse CD28 monoclonal antibody

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2751547

2 September 2018

Characterization of the gender dimorphism after injury and hemorrhagic shock: are hormonal differences responsible?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2751547

2 September 2018

CD28 provides T-cell costimulation and enhances PI3K activity at the immune synapse independently of its capacity to interact with the p85/p110 heterodimer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2751547

2 September 2018

Postburn monocytes are the major producers of TNF-alpha in the heterogeneous splenic macrophage population.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2751547

2 September 2018

CTLA4Ig: bridging the basic immunology with clinical application

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2751547

2 September 2018

Are the protective effects of 17beta-estradiol on splenic macrophages and splenocytes after trauma-hemorrhage mediated via estrogen-receptor (ER)-alpha or ER-beta?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2751547

2 September 2018

LPS-induced acute lung injury is attenuated by phosphodiesterase inhibition: effects on proinflammatory mediators, metalloproteinases, NF-kappaB, and ICAM-1 expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2751547

2 September 2018

Enhanced regulatory T cell activity is an element of the host response to injury.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2751547

2 September 2018

Influence of gender and age on T-cell responses in a murine model of trauma-hemorrhage: differences between circulating and tissue-fixed cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2751547

2 September 2018

Akt decreases lymphocyte apoptosis and improves survival in sepsis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2751547

2 September 2018

Diversity of clonal T cell proliferation is mediated by differential expression of CD152 (CTLA-4) on the cell surface of activated individual T lymphocytes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2751547

2 September 2018

Interaction between the innate and adaptive immune systems is required to survive sepsis and control inflammation after injury.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2751547

2 September 2018

Relationships between burn size, immunosuppression, and macrophage hyperactivity in a murine model of thermal injury

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2751547

2 September 2018

Deficiency of IL-2 or IL-6 reduces lymphocyte proliferation, but only IL-6 deficiency decreases the contact hypersensitivity response

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2751547

2 September 2018

Negative signaling contributes to T-cell anergy in trauma patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2751547

2 October 2018

Cutting edge: blockade of the CD28/B7 costimulatory pathway inhibits intestinal allograft rejection mediated by CD4+ but not CD8+ T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2751547

2 October 2018

Regulation of surface and intracellular expression of CTLA4 on mouse T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2751547

2 October 2018

Regulation of T cell receptor signaling by tyrosine phosphatase SYP association with CTLA-4

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2751547

2 October 2018

CD28 is required for T cell activation and IFN-gamma production by CD4+ and CD8+ T cells in response to Trypanosoma cruzi infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2751547

3 December 2018

Hemorrhage in mice induces alterations in immunoglobulin-secreting B cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/19729482

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Major injury leads to predominance of the T helper-2 lymphocyte phenotype and diminished interleukin-12 production associated with decreased resistance to infection

1 reference

https://pubmed.ncbi.nlm.nih.gov/19729482

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential induction of apoptosis in lymphoid tissues during sepsis: variation in onset, frequency, and the nature of the mediators

1 reference

https://pubmed.ncbi.nlm.nih.gov/19729482

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

T cell stimulation and expansion using anti-CD3/CD28 beads

1 reference

https://pubmed.ncbi.nlm.nih.gov/19729482

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Castration prevents suppression of MHC class II (Ia) expression on macrophages after trauma-hemorrhage

1 reference

https://pubmed.ncbi.nlm.nih.gov/19729482

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Trauma-hemorrhage induces depressed splenic dendritic cell functions in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/19729482

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased CD4+ CD25+ T regulatory cell activity in trauma patients depresses protective Th1 immunity

1 reference

https://pubmed.ncbi.nlm.nih.gov/19729482

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The PI3K/Akt pathway mediates the nongenomic cardioprotective effects of estrogen following trauma-hemorrhage

1 reference

https://pubmed.ncbi.nlm.nih.gov/19729482

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Salutary effects of 17beta-estradiol on T-cell signaling and cytokine production after trauma-hemorrhage are mediated primarily via estrogen receptor-alpha

1 reference

https://pubmed.ncbi.nlm.nih.gov/19729482

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanism of the nongenomic effects of estrogen on intestinal myeloperoxidase activity following trauma-hemorrhage: up-regulation of the PI-3K/Akt pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/19729482

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanism of estrogen-mediated attenuation of hepatic injury following trauma-hemorrhage: Akt-dependent HO-1 up-regulation

1 reference

https://pubmed.ncbi.nlm.nih.gov/19729482

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of MIP-1 alpha in the development of systemic inflammatory response and organ injury following trauma hemorrhage

1 reference

https://pubmed.ncbi.nlm.nih.gov/19729482

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.2353/AJPATH.2009.081174

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

ResearchGate publication ID

0 references

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q37362072&oldid=2134503641"