(Q28610410)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12670391%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

review article

1 reference

title

The PI-3 kinase/Akt pathway and T cell activation: pleiotropic pathways downstream of PIP3 (English)

2 references

3 February 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12670391%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

1 reference

1 reference

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12670391%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

2

Arthur Weiss

2 references

3 February 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12670391%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

publication date

1 April 2003

2 references

3 February 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12670391%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

published in

Immunological Reviews

2 references

3 February 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12670391%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

volume

192

2 references

3 February 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12670391%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

page(s)

7-20

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12670391%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

cites work

Phosphoinositide kinases

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00008.X

AKT/PKB and other D3 phosphoinositide-regulated kinases: kinase activation by phosphoinositide-dependent phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00008.X

Phosphoinositide 3-kinase in immunological systems

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00008.X

Tyrosine phosphorylation of the CD3-epsilon subunit of the T cell antigen receptor mediates enhanced association with phosphatidylinositol 3-kinase in Jurkat T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00008.X

T cell activation-dependent association between the p85 subunit of the phosphatidylinositol 3-kinase and Grb2/phospholipase C-gamma 1-binding phosphotyrosyl protein pp36/38.

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00008.X

T cell receptor (TCR) interacting molecule (TRIM), a novel disulfide-linked dimer associated with the TCR-CD3-zeta complex, recruits intracellular signaling proteins to the plasma membrane

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00008.X

New role for Shc in activation of the phosphatidylinositol 3-kinase/Akt pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00008.X

The T-cell receptor regulates Akt (protein kinase B) via a pathway involving Rac1 and phosphatidylinositide 3-kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00008.X

Phosphatidylinositol (PI) 3-kinase and PI 4-kinase binding to the CD4-p56lck complex: the p56lck SH3 domain binds to PI 3-kinase but not PI 4-kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00008.X

Targets of B-cell antigen receptor signaling: the phosphatidylinositol 3-kinase/Akt/glycogen synthase kinase-3 signaling pathway and the Rap1 GTPase

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00008.X

Requirement of Gab2 for mast cell development and KitL/c-Kit signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00008.X

Lymphocytes with a complex: adapter proteins in antigen receptor signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00008.X

Essential role for Gab2 in the allergic response

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00008.X

Complexities of CD28/B7: CTLA-4 costimulatory pathways in autoimmunity and transplantation

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00008.X

T-cell regulation by CD28 and CTLA-4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00008.X

The cytoplasmic domain of CD28 is both necessary and sufficient for costimulation of interleukin-2 secretion and association with phosphatidylinositol 3'-kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00008.X

CD28: a signalling perspective.

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00008.X

PI 3-kinase: a pivotal pathway in T-cell activation?

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00008.X

Phosphoinositide 3-kinases in T lymphocyte activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00008.X

CD28-mediated costimulation in the absence of phosphatidylinositol 3-kinase association and activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00008.X

Deficiency of PTEN in Jurkat T cells causes constitutive localization of Itk to the plasma membrane and hyperresponsiveness to CD3 stimulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00008.X

PI 3-K and T-cell activation: limitations of T-leukemic cell lines as signaling models.

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00008.X

Proliferative defect and embryonic lethality in mice homozygous for a deletion in the p110alpha subunit of phosphoinositide 3-kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00008.X

Xid-like immunodeficiency in mice with disruption of the p85alpha subunit of phosphoinositide 3-kinase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00008.X

Impaired B cell development and proliferation in absence of phosphoinositide 3-kinase p85alpha.

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00008.X

Function of PI3Kgamma in thymocyte development, T cell activation, and neutrophil migration

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00008.X

Lipid kinase and protein kinase activities of G-protein-coupled phosphoinositide 3-kinase gamma: structure-activity analysis and interactions with wortmannin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00008.X

Aggregation of the human high affinity immunoglobulin G receptor (FcgammaRI) activates both tyrosine kinase and G protein-coupled phosphoinositide 3-kinase isoforms.

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00008.X

p110delta, a novel phosphatidylinositol 3-kinase catalytic subunit that associates with p85 and is expressed predominantly in leukocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00008.X

p110δ, a novel phosphoinositide 3-kinase in leukocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00008.X

Signal-dependent membrane targeting by pleckstrin homology (PH) domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00008.X

Specificity in pleckstrin homology (PH) domain membrane targeting: a role for a phosphoinositide-protein co-operative mechanism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00008.X

Vav proteins, adaptors and cell signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00008.X

Two distinct regions of the CD28 intracytoplasmic domain are involved in the tyrosine phosphorylation of Vav and GTPase activating protein-associated p62 protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00008.X

Cbl-b regulates the CD28 dependence of T-cell activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00008.X

Cbl-b is a negative regulator of receptor clustering and raft aggregation in T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00008.X

Tyrosine-phosphorylated Vav1 as a point of integration for T-cell receptor- and CD28-mediated activation of JNK, p38, and interleukin-2 transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00008.X

A novel positive feedback loop mediated by the docking protein Gab1 and phosphatidylinositol 3-kinase in epidermal growth factor receptor signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00008.X

Akt provides the CD28 costimulatory signal for up-regulation of IL-2 and IFN-gamma but not TH2 cytokines

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00008.X

Akt1/PKBalpha is required for normal growth but dispensable for maintenance of glucose homeostasis in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00008.X

Growth retardation and increased apoptosis in mice with homozygous disruption of the Akt1 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00008.X

Insulin resistance and a diabetes mellitus-like syndrome in mice lacking the protein kinase Akt2 (PKB beta)

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00008.X

Membrane localization of phosphatidylinositol 3-kinase is sufficient to activate multiple signal-transducing kinase pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00008.X

Transcription factors of the NFAT family: regulation and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00008.X

New insights into the regulation and functions of Tec family tyrosine kinases in the immune system

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00008.X

PKB-mediated negative feedback tightly regulates mitogenic signalling via Gab2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00008.X

Autophosphorylation of p110δ phosphoinositide 3-kinase: a new paradigm for the regulation of lipid kinases in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00008.X

Induction of NF-kappaB by the Akt/PKB kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00008.X

NF-kappaB activation by tumour necrosis factor requires the Akt serine-threonine kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00008.X

NF-kappaB is a target of AKT in anti-apoptotic PDGF signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00008.X

Distinct roles of the Ikappa B kinase alpha and beta subunits in liberating nuclear factor kappa B (NF-kappa B) from Ikappa B and in phosphorylating the p65 subunit of NF-kappa B.

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00008.X

Akt suppresses apoptosis by stimulating the transactivation potential of the RelA/p65 subunit of NF-kappaB.

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00008.X

Oncogenic Ha-Ras-induced signaling activates NF-kappaB transcriptional activity, which is required for cellular transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00008.X

Protein kinase B regulates T lymphocyte survival, nuclear factor kappaB activation, and Bcl-X(L) levels in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00008.X

Akt-dependent phosphorylation specifically regulates Cot induction of NF-kappa B-dependent transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00008.X

It's all Rel-ative: NF-kappaB and CD28 costimulation of T-cell activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00008.X

Genetic evidence for Shc requirement in TCR-induced c-Rel nuclear translocation and IL-2 expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00008.X

Ten years of protein kinase B signalling: a hard Akt to follow

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00008.X

A phosphoinositide-binding sequence is shared by PH domain target molecules--a model for the binding of PH domains to proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00008.X

AH/PH domain-mediated interaction between Akt molecules and its potential role in Akt regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00008.X

The akt kinase: molecular determinants of oncogenicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00008.X

Glycogen synthase kinase-3: properties, functions, and regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00008.X

Requirement for glycogen synthase kinase-3beta in cell survival and NF-kappaB activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00008.X

Phosphorylation meets ubiquitination: the control of NF-[kappa]B activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00008.X

Negative regulation of T cell proliferation and interleukin 2 production by the serine threonine kinase GSK-3

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00008.X

Cell cycle and death control: long live Forkheads

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00008.X

The Fork head transcription factor DAF-16 transduces insulin-like metabolic and longevity signals in C. elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00008.X

daf-16: An HNF-3/forkhead family member that can function to double the life-span of Caenorhabditis elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00008.X

Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00008.X

The forkhead transcription factor FoxO regulates transcription of p27Kip1 and Bim in response to IL-2

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00008.X

Expression of the pro-apoptotic Bcl-2 family member Bim is regulated by the forkhead transcription factor FKHR-L1

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00008.X

Nuclear export of NF-ATc enhanced by glycogen synthase kinase-3

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00008.X

Glycogen synthase kinase-3 inhibits the DNA binding activity of NFATc

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00008.X

CD28 utilizes Vav-1 to enhance TCR-proximal signaling and NF-AT activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00008.X

Genomic expression programs and the integration of the CD28 costimulatory signal in T cell activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00008.X

Modulation of TCR-induced transcriptional profiles by ligation of CD28, ICOS, and CTLA-4 receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00008.X

CREB is a regulatory target for the protein kinase Akt/PKB

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00008.X

The antiapoptotic gene mcl-1 is up-regulated by the phosphatidylinositol 3-kinase/Akt signaling pathway through a transcription factor complex containing CREB

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00008.X

Constitutively activated Akt-1 is vital for the survival of human monocyte-differentiated macrophages. Role of Mcl-1, independent of nuclear factor (NF)-kappaB, Bad, or caspase activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00008.X

AKT induces transcriptional activity of PU.1 through phosphorylation-mediated modifications within its transactivation domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00008.X

CD28 costimulation can promote T cell survival by enhancing the expression of Bcl-XL.

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00008.X

The Rel/NF-kappaB family directly activates expression of the apoptosis inhibitor Bcl-x(L).

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00008.X

The NF-kappa B cascade is important in Bcl-xL expression and for the anti-apoptotic effects of the CD28 receptor in primary human CD4+ lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00008.X

CD28-dependent activation of protein kinase B/Akt blocks Fas-mediated apoptosis by preventing death-inducing signaling complex assembly.

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00008.X

Regulation of T cell development in the thymus

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00008.X

Induction of the early growth response (Egr) family of transcription factors during thymic selection

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00008.X

Thymocyte development in early growth response gene 1-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00008.X

Interleukin-3-induced phosphorylation of BAD through the protein kinase Akt

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00008.X

Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00008.X

p70(s6k) integrates phosphatidylinositol 3-kinase and rapamycin-regulated signals for E2F regulation in T lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00008.X

Ribosomal S6 kinase signaling and the control of translation

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00008.X

Regulation of translation initiation factors by signal transduction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00008.X

Role of translation initiation factor 2B in control of cell survival by the phosphatidylinositol 3-kinase/Akt/glycogen synthase kinase 3beta signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00008.X

Glucose stimulates the activity of the guanine nucleotide-exchange factor eIF-2B in isolated rat islets of Langerhans

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00008.X

The regulation of protein synthesis and translation factors by CD3 and CD28 in human primary T lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00008.X

Signal transduction by the TCR for antigen

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00008.X

Signalling scaffolds and adaptors in T-cell immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00008.X

Protein kinase B (Akt) regulation and function in T lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00008.X

Cellular survival: a play in three Akts

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00008.X

Regulation of D-3 phosphoinositides during T cell activation via the T cell antigen receptor/CD3 complex and CD2 antigens

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00008.X

7 January 2021

The protein interactions of the immunoglobulin receptor family tyrosine-based activation motifs present in the T cell receptor zeta subunits and the CD3 gamma, delta and epsilon chains

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00008.X

7 January 2021

A negative role for phosphoinositide 3-kinase in T-cell antigen receptor function

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00008.X

7 January 2021

Cutting edge: gab2 mediates an inhibitory phosphatidylinositol 3'-kinase pathway in T cell antigen receptor signaling

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00008.X

7 January 2021

T-cell antigen CD28 interacts with the lipid kinase phosphatidylinositol 3-kinase by a cytoplasmic Tyr(P)-Met-Xaa-Met motif

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00008.X

7 January 2021

Stimulation of CD28 triggers an association between CD28 and phosphatidylinositol 3-kinase in Jurkat T cells

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00008.X

7 January 2021

p56Lck and p59Fyn regulate CD28 binding to phosphatidylinositol 3-kinase, growth factor receptor-bound protein GRB-2, and T cell-specific protein-tyrosine kinase ITK: implications for T-cell costimulation

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00008.X

7 January 2021

The CD28 and CTLA-4 receptors associate with the serine/threonine phosphatase PP2A.

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00008.X

7 January 2021

T cell antigen CD28 binds to the GRB-2/SOS complex, regulators of p21ras

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00008.X

7 January 2021

Selective CD28pYMNM mutations implicate phosphatidylinositol 3-kinase in CD86-CD28-mediated costimulation

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00008.X

7 January 2021

Crystal structures of the XLP protein SAP reveal a class of SH2 domains with extended, phosphotyrosine-independent sequence recognition

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00008.X

7 January 2021

Molecular balance between the regulatory and catalytic subunits of phosphoinositide 3-kinase regulates cell signaling and survival.

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00008.X

7 January 2021

Reduced expression of the murine p85alpha subunit of phosphoinositide 3-kinase improves insulin signaling and ameliorates diabetes

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00008.X

7 January 2021

Linkage of G protein-coupled receptors to the MAPK signaling pathway through PI 3-kinase gamma

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00008.X

7 January 2021

Ligation of the T cell co-stimulatory receptor CD28 activates the serine-threonine protein kinase protein kinase B.

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00008.X

7 January 2021

The T cell antigen receptor activates phosphatidylinositol 3-kinase-regulated serine kinases protein kinase B and ribosomal S6 kinase 1

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00008.X

7 January 2021

The CD28 signaling pathway regulates glucose metabolism

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00008.X

7 January 2021

CD28 costimulation mediates down-regulation of p27kip1 and cell cycle progression by activation of the PI3K/PKB signaling pathway in primary human T cells

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00008.X

7 January 2021

Caenorhabditis elegans Akt/PKB transduces insulin receptor-like signals from AGE-1 PI3 kinase to the DAF-16 transcription factor

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00008.X

7 January 2021

T-cell signalling and autoimmunity: molecular mechanisms of disease

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00008.X

7 January 2021

Activated T cell death in vivo mediated by proapoptotic bcl-2 family member bim.

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00008.X

7 January 2021

Protection of CD95-mediated apoptosis by activation of phosphatidylinositide 3-kinase and protein kinase B

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00008.X

7 January 2021

Impaired Fas response and autoimmunity in Pten+/- mice

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00008.X

7 January 2021

The insulin-like growth factor-I receptor is regulated by CD28 and protects activated T cells from apoptosis

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00008.X

7 January 2021

Signaling pathways mediating insulin-stimulated glucose transport

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00008.X

7 January 2021

CD28 costimulation mediates T cell expansion via IL-2-independent and IL-2-dependent regulation of cell cycle progression

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00008.X

7 January 2021

Signal transduction pathways that contribute to increased protein synthesis during T-cell activation

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00008.X

7 January 2021

The effect of the immunosuppressant FK-506 on alternate pathways of T cell activation

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00008.X

7 January 2021

Rapamycin blocks the phosphorylation of 4E-BP1 and inhibits cap-dependent initiation of translation

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00008.X

7 January 2021

4E-BP1, a repressor of mRNA translation, is phosphorylated and inactivated by the Akt(PKB) signaling pathway

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00008.X

7 January 2021

Identification of the tuberous sclerosis complex-2 tumor suppressor gene product tuberin as a target of the phosphoinositide 3-kinase/akt pathway

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00008.X

7 January 2021

T-cell activation leads to rapid stimulation of translation initiation factor eIF2B and inactivation of glycogen synthase kinase-3

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00008.X

7 January 2021

10.1034/J.1600-065X.2003.00008.X

Identifiers

DOI

2 references

Consolidated OpenCitations Corpus – April 2017

907886

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12670391%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

907886

1 reference

Consolidated OpenCitations Corpus – April 2017

Consolidated OpenCitations Corpus – April 2017

2 references

907886