(Q37371387)

English

WIN55,212-2, a cannabinoid receptor agonist, protects against nigrostriatal cell loss in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson's disease.

scientific article published on 21 May 2009

WIN55,212-2, a cannabinoid receptor agonist, protects against nigrostriatal cell loss in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson’s disease

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scholarly article

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29 January 2020

WIN55,212-2, a cannabinoid receptor agonist, protects against nigrostriatal cell loss in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson's disease (English)

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29 January 2020

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cannabinoid receptor

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Parkinson's disease

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based on heuristic

inferred from title

Emilio F. Espejo

6

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29 January 2020

Giovanni Marsicano

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29 January 2020

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David A Price

1

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29 January 2020

Alex A Martinez

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29 January 2020

Alexandre Seillier

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Wouter Koek

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Yolanda Acosta

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Randy Strong

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Beat Lutz

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James L Roberts

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Andrea Giuffrida

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29 January 2020

European Journal of Neuroscience

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2177-2186

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29 January 2020

Cannabinoids and neuroprotection in basal ganglia disorders.

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6 September 2017

Anti-dyskinetic effects of cannabinoids in a rat model of Parkinson's disease: role of CB(1) and TRPV1 receptors.

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6 September 2017

Cannabinoids go nuclear: evidence for activation of peroxisome proliferator-activated receptors.

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6 September 2017

Cannabinoid CB1 receptor stimulation affords neuroprotection in MPTP-induced neurotoxicity by attenuating S100B up-regulation in vitro

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6 September 2017

The endocannabinoid system in targeting inflammatory neurodegenerative diseases

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6 September 2017

CB1-independent inhibition of dopamine transporter activity by cannabinoids in mouse dorsal striatum

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6 September 2017

Microglia-mediated neurotoxicity: uncovering the molecular mechanisms

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6 September 2017

Monoamine metabolism and behavioral responses to ethanol in mitochondrial aldehyde dehydrogenase knockout mice

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6 September 2017

Behavioral phenotypes and pharmacology in genetic mouse models of Parkinsonism

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6 September 2017

Behavioral effects of dopaminergic agonists in transgenic mice overexpressing human wildtype alpha-synuclein

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6 September 2017

AM1241, a cannabinoid CB2 receptor selective compound, delays disease progression in a mouse model of amyotrophic lateral sclerosis

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6 September 2017

The endocannabinoid system promotes astroglial differentiation by acting on neural progenitor cells.

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6 September 2017

Identification and functional characterization of brainstem cannabinoid CB2 receptors

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6 September 2017

Treatment of Parkinson's disease : what's on the horizon?

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6 September 2017

Prevention of Alzheimer's disease pathology by cannabinoids: neuroprotection mediated by blockade of microglial activation.

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6 September 2017

Endovanilloids. Putative endogenous ligands of transient receptor potential vanilloid 1 channels

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6 September 2017

Challenges in Parkinson's disease: restoration of the nigrostriatal dopamine system is not enough

1 reference

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6 September 2017

Cannabinoids and neuroinflammation

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6 September 2017

Neuroprotection in Parkinson disease: mysteries, myths, and misconceptions

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6 September 2017

Cannabinoid CB2 receptors and fatty acid amide hydrolase are selectively overexpressed in neuritic plaque-associated glia in Alzheimer's disease brains

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6 September 2017

CB1 cannabinoid receptors and on-demand defense against excitotoxicity

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6 September 2017

Parkinson's disease: mechanisms and models

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6 September 2017

Neuroprotective strategies in Parkinson's disease : an update on progress

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6 September 2017

The role of glial reaction and inflammation in Parkinson's disease.

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6 September 2017

Neuroprotective agents for clinical trials in Parkinson's disease: a systematic assessment

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6 September 2017

Neuroinflammatory processes in Parkinson's disease.

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6 September 2017

Nonpsychotropic cannabinoid receptors regulate microglial cell migration.

1 reference

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6 September 2017

Behavioral phenotyping of the MPTP mouse model of Parkinson's disease

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6 September 2017

An endogenous cannabinoid (2-AG) is neuroprotective after brain injury

1 reference

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6 September 2017

The role of glial cells in Parkinson's disease

1 reference

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6 September 2017

The parkinsonian toxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP): a technical review of its utility and safety

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2755595

6 September 2017

Cannabinoid CB1 receptor knockout mice fail to self-administer morphine but not other drugs of abuse

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6 September 2017

Endocannabinoids and vascular function.

1 reference

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6 September 2017

Evidence of active nerve cell degeneration in the substantia nigra of humans years after 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine exposure

1 reference

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6 September 2017

Glial pathology but absence of apoptotic nigral neurons in long-standing Parkinson's disease

1 reference

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6 September 2017

Reactive microglia are positive for HLA-DR in the substantia nigra of Parkinson's and Alzheimer's disease brains

1 reference

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6 September 2017

The absolute number of nerve cells in substantia nigra in normal subjects and in patients with Parkinson's disease estimated with an unbiased stereological method

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6 September 2017

Neuropathologic features of Parkinson's, Huntington's, and Alzheimer's diseases

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6 September 2017

The MPTP-treated mouse as a model of parkinsonism: how good is it?

1 reference

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6 September 2017

Anandamide inhibits nuclear factor-kappaB activation through a cannabinoid receptor-independent pathway.

1 reference

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14 September 2017

Neuroprotective properties of cannabinoids against oxidative stress: role of the cannabinoid receptor CB1.

1 reference

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28 September 2017

Induction of interleukin-1 associated with compensatory dopaminergic sprouting in the denervated striatum of young mice: model of aging and neurodegenerative disease.

1 reference

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28 September 2017

Cytotoxicity of microglia

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28 September 2017

New stereological methods for counting neurons

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28 September 2017

Endocannabinoid-mediated rescue of striatal LTD and motor deficits in Parkinson's disease models

1 reference

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26 June 2018

Endogenous interleukin-1 receptor antagonist mediates anti-inflammatory and neuroprotective actions of cannabinoids in neurons and glia.

1 reference

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26 June 2018

The biodisposition of MPP+ in mouse brain

1 reference

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26 June 2018

Transgenic mice with increased Cu/Zn-superoxide dismutase activity are resistant to N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neurotoxicity

1 reference

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26 June 2018

Opposing control of cannabinoid receptor stimulation on amyloid-beta-induced reactive gliosis: in vitro and in vivo evidence.

1 reference

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2 September 2018

Cannabinoids inhibit sodium-dependent, high-affinity excitatory amino acid transport in cultured rat cortical astrocytes.

1 reference

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2 September 2018

Evaluation of the neuroprotective effect of cannabinoids in a rat model of Parkinson's disease: importance of antioxidant and cannabinoid receptor-independent properties.

1 reference

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2 September 2018

Increasing cannabinoid levels by pharmacological and genetic manipulation delay disease progression in SOD1 mice.

1 reference

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2 September 2018

The endocannabinoid anandamide protects neurons during CNS inflammation by induction of MKP-1 in microglial cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2755595

2 September 2018

Effect of anandamide uptake inhibition in the production of nitric oxide and in the release of cytokines in astrocyte cultures.

1 reference

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2 September 2018

A role for endocannabinoids in the generation of parkinsonism and levodopa-induced dyskinesia in MPTP-lesioned non-human primate models of Parkinson's disease

1 reference

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2 September 2018

Cannabinoids provide neuroprotection against 6-hydroxydopamine toxicity in vivo and in vitro: relevance to Parkinson's disease

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2 September 2018

Early and progressive sensorimotor anomalies in mice overexpressing wild-type human alpha-synuclein.

1 reference

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2 September 2018

CB1 receptor knockout mice display reduced ethanol-induced conditioned place preference and increased striatal dopamine D2 receptors.

1 reference

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2 September 2018

Therapeutic action of cannabinoids in a murine model of multiple sclerosis.

1 reference

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2 September 2018

Grid performance test to measure behavioral impairment in the MPTP-treated-mouse model of parkinsonism

1 reference

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2 September 2018

Stimulation of cannabinoid receptors reduces levodopa-induced dyskinesia in the MPTP-lesioned nonhuman primate model of Parkinson's disease

1 reference

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2 September 2018

Detection of behavioral impairments correlated to neurochemical deficits in mice treated with moderate doses of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine

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2 September 2018

The endogenous cannabinoid system controls extinction of aversive memories

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2 September 2018

Blockade of microglial activation is neuroprotective in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson disease.

1 reference

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2 September 2018

Cannabinoids reduce levodopa-induced dyskinesia in Parkinson's disease: a pilot study

1 reference

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2 September 2018

Cannabinoid receptor agonist and antagonist effects on motor function in normal and 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine (MPTP)-treated non-human primates.

1 reference

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2 September 2018

The inflammatory reaction following 1-methyl-4-phenyl-1,2,3, 6-tetrahydropyridine intoxication in mouse.

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2 September 2018

Cannabinoids and neuroprotection in global and focal cerebral ischemia and in neuronal cultures.

1 reference

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2 September 2018

The overall rod performance test in the MPTP-treated-mouse model of Parkinsonism.

1 reference

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2 September 2018

Microglial and astrocytic involvement in a murine model of Parkinson's disease induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP).

1 reference

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2 September 2018

Differences in pre- and post-synaptic sensitivity to apomorphine between saline and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated C57BL/6 mice as reflected in climbing activity.

1 reference

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2 September 2018

Lowering ambient or core body temperature elevates striatal MPP+ levels and enhances toxicity to dopamine neurons in MPTP-treated mice.

1 reference

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2 September 2018

Cannabinoid receptor agonists inhibit glutamatergic synaptic transmission in rat hippocampal cultures.

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2 September 2018

Inducible nitric oxide synthase stimulates dopaminergic neurodegeneration in the MPTP model of Parkinson disease

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2 October 2018

The single intranigral injection of LPS as a new model for studying the selective effects of inflammatory reactions on dopaminergic system

1 reference

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3 December 2018

[Cannabinoid system and neuroinflammation:therapeutic perspectives in multiple sclerosis]

1 reference

https://pubmed.ncbi.nlm.nih.gov/19490092

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanisms of the inotropic actions of MPTP and MPP+ on isolated atria of rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/19490092

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Microglia: Intrinsic immuneffector cell of the brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/19490092

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Time course and morphology of dopaminergic neuronal death caused by the neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine

1 reference

https://pubmed.ncbi.nlm.nih.gov/19490092

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Microglial reaction in MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) induced Parkinson's disease mice model

1 reference

https://pubmed.ncbi.nlm.nih.gov/19490092

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

MPTP-induced deficits in motor activity: neuroprotective effects of the spintrapping agent, alpha-phenyl-tert-butyl-nitrone (PBN)

1 reference

https://pubmed.ncbi.nlm.nih.gov/19490092

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Deficiency of inducible nitric oxide synthase protects against MPTP toxicity in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/19490092

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regional difference in susceptibility to lipopolysaccharide-induced neurotoxicity in the rat brain: role of microglia

1 reference

https://pubmed.ncbi.nlm.nih.gov/19490092

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1111/J.1460-9568.2009.06764.X

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19490092%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19490092%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19490092%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

ResearchGate publication ID

0 references

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