(Q37384095)

20 August 2017

p53 isoforms regulate aging- and tumor-associated replicative senescence in T lymphocytes (English)

1 reference

20 August 2017

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David P Lane

11

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Maria A Blasco

object named as

Maria A Blasco

10

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Bořivoj Vojtěšek

9

object named as

Borivoj Vojtesek

1 reference

20 August 2017

Abdul M Mondal

1

1 reference

20 August 2017

Izumi Horikawa

2

1 reference

20 August 2017

Sharon R Pine

3

1 reference

20 August 2017

Kaori Fujita

4

1 reference

20 August 2017

Katherine M Morgan

5

1 reference

20 August 2017

Elsa Vera

6

1 reference

20 August 2017

Sharlyn J Mazur

7

1 reference

20 August 2017

Ettore Appella

8

1 reference

20 August 2017

Curtis C Harris

12

1 reference

20 August 2017

language of work or name

English

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publication date

15 November 2013

1 reference

20 August 2017

11

1 reference

Journal of Clinical Investigation

inferred from page(s)

published in

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20 August 2017

123

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20 August 2017

12

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20 August 2017

5247-5257

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describes a project that uses

20 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3859419/fullTextXML

inferred from PubMed Central ID database lookup

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Detecting p53 isoforms at protein level

6 September 2017

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Downregulation of splicing factor SRSF3 induces p53β, an alternatively spliced isoform of p53 that promotes cellular senescence

6 September 2017

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6 September 2017

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6 September 2017

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Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders

6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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Sustained CD28 expression delays multiple features of replicative senescence in human CD8 T lymphocytes

6 September 2017

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6 September 2017

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The isoforms of the p53 protein

6 September 2017

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Microenvironmental modulation of asymmetric cell division in human lung cancer cells

6 September 2017

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The senescence-associated secretory phenotype: the dark side of tumor suppression

6 September 2017

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p53 isoforms Delta133p53 and p53beta are endogenous regulators of replicative cellular senescence

6 September 2017

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Differentiation stage determines potential of hematopoietic cells for reprogramming into induced pluripotent stem cells

6 September 2017

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Immunosenescence: what does it mean to health outcomes in older adults?

6 September 2017

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Senescence-messaging secretome: SMS-ing cellular stress

6 September 2017

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6 September 2017

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High-throughput telomere length quantification by FISH and its application to human population studies

6 September 2017

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Oncogene-induced senescence is part of the tumorigenesis barrier imposed by DNA damage checkpoints

6 September 2017

1 reference

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A novel role for high-mobility group a proteins in cellular senescence and heterochromatin formation

6 September 2017

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CD8+ T-cell memory in tumor immunology and immunotherapy

6 September 2017

1 reference

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p53 isoforms can regulate p53 transcriptional activity.

6 September 2017

1 reference

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The role of CD8+ T-cell replicative senescence in human aging

6 September 2017

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Replicative senescence of CD8 T cells: effect on human ageing

6 September 2017

1 reference

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Replicative senescence: the final stage of memory T cell differentiation?

6 September 2017

1 reference

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THE LIMITED IN VITRO LIFETIME OF HUMAN DIPLOID CELL STRAINS

6 September 2017

1 reference

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Expression of CD57 defines replicative senescence and antigen-induced apoptotic death of CD8+ T cells

6 September 2017

1 reference

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Increased expression of NK cell markers on T lymphocytes in aging and chronic activation of the immune system reflects the accumulation of effector/senescent T cells

6 September 2017

1 reference

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Extension of life-span by introduction of telomerase into normal human cells

6 September 2017

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A global measure of perceived stress

6 September 2017

1 reference

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The telomere hypothesis of cellular aging

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3859419

Tumor-induced senescent T cells with suppressor function: a potential form of tumor immune evasion.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3859419

NF-kappaB activation represses tumor necrosis factor-alpha-induced autophagy

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3859419

Senescing human cells and ageing mice accumulate DNA lesions with unrepairable double-strand breaks

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3859419

CD28: a signalling perspective.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3859419

mTOR inhibits autophagy by controlling ULK1 ubiquitylation, self-association and function through AMBRA1 and TRAF6.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3859419

Tumour biology: senescence in premalignant tumours

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3859419

Telomere length dynamics in human lymphocyte subpopulations measured by flow cytometry.

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3859419

Coming of age: molecular drivers of aging and therapeutic opportunities

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3859419

Molecular pathways: next-generation immunotherapy--inhibiting programmed death-ligand 1 and programmed death-1.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3859419

Senescence surveillance of pre-malignant hepatocytes limits liver cancer development.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3859419

A simplified method for the clinical-scale generation of central memory-like CD8+ T cells after transduction with lentiviral vectors encoding antitumor antigen T-cell receptors.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3859419

Telomere uncapping during in vitro T-lymphocyte senescence.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3859419

Decreased perforin and granzyme B expression in senescent HIV-1-specific cytotoxic T lymphocytes

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3859419

Nonantigen specific CD8+ T suppressor lymphocytes originate from CD8+CD28- T cells and inhibit both T-cell proliferation and CTL function.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3859419

Proliferative arrest and cell cycle regulation in CD8(+)CD28(-) versus CD8(+)CD28(+) T cells

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3859419

Shortened telomeres in the expanded CD28-CD8+ cell subset in HIV disease implicate replicative senescence in HIV pathogenesis.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3859419

Accelerated replicative senescence of the peripheral immune system induced by HIV infection

2 September 2018

1 reference

12 December 2020

Proliferation of CD8+ in culture of human T cells derived from peripheral blood of adult donors and cord blood of newborns

1 reference

12 December 2020

Human T lymphocytes possess a limited in vitro life span

1 reference

12 December 2020

Shortened telomeres in clonally expanded CD28-CD8+ T cells imply a replicative history that is distinct from their CD28+CD8+ counterparts

1 reference

12 December 2020

Decline in CD28+ T cells in centenarians and in long-term T cell cultures: a possible cause for both in vivo and in vitro immunosenescence

1 reference

12 December 2020

Identifiers

DOI

10.1172/JCI70355

1 reference

20 August 2017

1 reference

20 August 2017

1 reference