(Q37413723)

English

{beta}3-integrin expression on tumor cells inhibits tumor progression, reduces metastasis, and is associated with a favorable prognosis in patients with ovarian cancer.

scientific article published on October 2009

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scholarly article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19808644%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

{beta}3-integrin expression on tumor cells inhibits tumor progression, reduces metastasis, and is associated with a favorable prognosis in patients with ovarian cancer (English)

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19808644%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

0 references

1 reference

based on heuristic

inferred from title

tumor progression

1 reference

based on heuristic

inferred from title

9

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19808644%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

author name string

Swayamjot Kaur

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19808644%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

Hilary A Kenny

2

1 reference

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19808644%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

Sujatha Jagadeeswaran

3

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9 February 2020

Marion R Zillhardt

4

1 reference

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19808644%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

Anthony G Montag

5

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19808644%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

Emily Kistner

6

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19808644%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

S Diane Yamada

7

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19808644%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

Anirban K Mitra

8

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19808644%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

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1 October 2009

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9 February 2020

The American Journal of Pathology

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19808644%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

175

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19808644%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

5

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19808644%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

2184-2196

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19808644%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

Proapoptotic function of integrin beta(3) in human hepatocellular carcinoma cells.

1 reference

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6 September 2017

Loss of E-cadherin promotes ovarian cancer metastasis via alpha 5-integrin, which is a therapeutic target

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2774080

6 September 2017

The initial steps of ovarian cancer cell metastasis are mediated by MMP-2 cleavage of vitronectin and fibronectin.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2774080

6 September 2017

Cancer statistics, 2008

1 reference

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6 September 2017

Phase I and pharmacokinetic study of etaracizumab (Abegrin), a humanized monoclonal antibody against alphavbeta3 integrin receptor, in patients with advanced solid tumors.

1 reference

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6 September 2017

Let-7 expression defines two differentiation stages of cancer

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6 September 2017

Phase I and correlative biology study of cilengitide in patients with recurrent malignant glioma.

1 reference

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6 September 2017

14-3-3 proteins in cell cycle regulation

1 reference

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6 September 2017

Tumor-specific expression of alphavbeta3 integrin promotes spontaneous metastasis of breast cancer to bone.

1 reference

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6 September 2017

Microtubule-targeted anticancer agents and apoptosis

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6 September 2017

Clinical significance of urokinase-type plasminogen activator receptor (uPAR) expression in cancer

1 reference

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6 September 2017

The pathogenesis of cancer metastasis: the 'seed and soil' hypothesis revisited

1 reference

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6 September 2017

Integrins: bidirectional, allosteric signaling machines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2774080

6 September 2017

Cilengitide targeting of alpha(v)beta(3) integrin receptor synergizes with radioimmunotherapy to increase efficacy and apoptosis in breast cancer xenografts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2774080

6 September 2017

Overexpression of alpha(v)beta6 integrin in serous epithelial ovarian cancer regulates extracellular matrix degradation via the plasminogen activation cascade

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2774080

6 September 2017

Survival effect of maximal cytoreductive surgery for advanced ovarian carcinoma during the platinum era: a meta-analysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2774080

6 September 2017

Ovarian surface epithelium: biology, endocrinology, and pathology

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2774080

6 September 2017

beta(3)A-integrin downregulates the urokinase-type plasminogen activator receptor (u-PAR) through a PEA3/ets transcriptional silencing element in the u-PAR promoter

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2774080

6 September 2017

Activation mechanisms of the urokinase-type plasminogen activator promoter by hepatocyte growth factor/scatter factor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2774080

6 September 2017

p53 regulates a G2 checkpoint through cyclin B1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2774080

6 September 2017

Adenoviral gene transfer of beta3 integrin subunit induces conversion from radial to vertical growth phase in primary human melanoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2774080

6 September 2017

14-3-3sigma is a p53-regulated inhibitor of G2/M progression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2774080

6 September 2017

Requirement of vascular integrin alpha v beta 3 for angiogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2774080

6 September 2017

Wild-type p53 induces apoptosis of myeloid leukaemic cells that is inhibited by interleukin-6

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2774080

6 September 2017

Pathology of the peritoneum: a review of selected topics

1 reference

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6 September 2017

Role of the alpha v beta 3 integrin in human melanoma cell invasion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2774080

6 September 2017

Tumor alphavbeta3 integrin is a therapeutic target for breast cancer bone metastases.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2774080

14 September 2017

Intracranial microenvironment reveals independent opposing functions of host alphaVbeta3 expression on glioma growth and angiogenesis

1 reference

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14 September 2017

Migration properties of the human ovarian adenocarcinoma cell line IGROV1: importance of alpha(v)beta3 integrins and vitronectin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2774080

28 September 2017

Integrin beta 3 cDNA transfection into a highly metastatic alpha v beta 3-negative human melanoma cell line inhibits invasion and experimental metastasis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2774080

28 September 2017

Enhanced c-erbB-2/neu expression in human ovarian cancer cells correlates with more severe malignancy that can be suppressed by E1A.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2774080

26 June 2018

Stimulation of tumor growth and angiogenesis by low concentrations of RGD-mimetic integrin inhibitors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2774080

2 September 2018

The tubal fimbria is a preferred site for early adenocarcinoma in women with familial ovarian cancer syndrome.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2774080

2 September 2018

Inhibition of alpha(v)beta3 integrin survival signaling enhances antiangiogenic and antitumor effects of radiotherapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2774080

2 September 2018

Expression of alpha V-associated integrin beta subunits in epithelial ovarian cancer and its relation to prognosis in patients treated with platinum-based regimens.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2774080

2 September 2018

Integrin beta3 overexpression suppresses tumor growth in a human model of gliomagenesis: implications for the role of beta3 overexpression in glioblastoma multiforme

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2774080

2 September 2018

Increased expression of matrix metalloproteinases (MMP)-2, MMP-9, and the urokinase-type plasminogen activator is associated with progression from benign to advanced ovarian cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2774080

2 September 2018

Integrin alpha(v)beta(3)/vitronectin interaction affects expression of the urokinase system in human ovarian cancer cells

1 reference

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2 September 2018

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1 reference

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3 December 2018

Enhanced pathological angiogenesis in mice lacking β3 integrin or β3 and β5 integrins

1 reference

https://pubmed.ncbi.nlm.nih.gov/19808644

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of alpha(v)beta3 integrin reduces angiogenesis, bone turnover, and tumor cell proliferation in experimental prostate cancer bone metastases

1 reference

https://pubmed.ncbi.nlm.nih.gov/19808644

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression and localization of alpha v integrins and their ligand vitronectin in normal ovarian epithelium and in ovarian carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/19808644

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of alpha(v)beta3 integrin is less frequent in ovarian epithelial tumors of low malignant potential in contrast to ovarian carcinomas

1 reference

https://pubmed.ncbi.nlm.nih.gov/19808644

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Beta1-integrins partly mediate binding of ovarian cancer cells to peritoneal mesothelium in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/19808644

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

alphavbeta3 and vitronectin expression by normal ovarian surface epithelial cells: role in cell adhesion and cell proliferation

1 reference

https://pubmed.ncbi.nlm.nih.gov/19808644

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

c-Met overexpression is a prognostic factor in ovarian cancer and an effective target for inhibition of peritoneal dissemination and invasion

1 reference

https://pubmed.ncbi.nlm.nih.gov/19808644

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Use of a novel 3D culture model to elucidate the role of mesothelial cells, fibroblasts and extra-cellular matrices on adhesion and invasion of ovarian cancer cells to the omentum

1 reference

https://pubmed.ncbi.nlm.nih.gov/19808644

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.2353/AJPATH.2009.090028

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19808644%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19808644%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19808644%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

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