(Q37424309)

20 August 2017

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title

Pharmacogenetics in diabetes (English)

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20 August 2017

Ewan R Pearson

1

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publication date

1 April 2009

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20 August 2017

Current diabetes report

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20 August 2017

9

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20 August 2017

2

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20 August 2017

172-181

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https://scigraph.springernature.com/pub.10.1007/s11892-009-0028-3

20 August 2017

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cites work

Genome-wide association studies provide new insights into type 2 diabetes aetiology

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS11892-009-0028-3

Activating mutations in the gene encoding the ATP-sensitive potassium-channel subunit Kir6.2 and permanent neonatal diabetes

21 January 2018

1 reference

12 December 2020

The E23K variant of KCNJ11 encoding the pancreatic beta-cell adenosine 5'-triphosphate-sensitive potassium channel subunit Kir6.2 is associated with an increased risk of secondary failure to sulfonylurea in patients with type 2 diabetes.

1 reference

12 December 2020

A functional variant in the peroxisome proliferator-activated receptor gamma2 promoter is associated with predictors of obesity and type 2 diabetes in Pima Indians

1 reference

12 December 2020

Haplotype structures and large-scale association testing of the 5' AMP-activated protein kinase genes PRKAA2, PRKAB1, and PRKAB2 [corrected] with type 2 diabetes

1 reference

12 December 2020

Association studies of variants in promoter and coding regions of beta-cell ATP-sensitive K-channel genes SUR1 and Kir6.2 with Type 2 diabetes mellitus (UKPDS 53).

1 reference

12 December 2020

Single nucleotide polymorphisms in genes encoding LKB1 (STK11), TORC2 (CRTC2) and AMPK alpha2-subunit (PRKAA2) and risk of type 2 diabetes.

1 reference

12 December 2020

Association between CYP2C9 slow metabolizer genotypes and severe hypoglycaemia on medication with sulphonylurea hypoglycaemic agents

1 reference

12 December 2020

Ser1369Ala variant in sulfonylurea receptor gene ABCC8 is associated with antidiabetic efficacy of gliclazide in Chinese type 2 diabetic patients

1 reference

12 December 2020

Involvement of organic cation transporter 1 in hepatic and intestinal distribution of metformin

1 reference

12 December 2020

The influence of adiponectin gene polymorphism on the rosiglitazone response in patients with type 2 diabetes

1 reference

12 December 2020

Activating mutations in the ABCC8 gene in neonatal diabetes mellitus

1 reference

12 December 2020

The association of adiponectin allele 45T/G and -11377C/G polymorphisms with Type 2 diabetes and rosiglitazone response in Chinese patients

1 reference

12 December 2020

Genetic cause of hyperglycaemia and response to treatment in diabetes

1 reference

12 December 2020

The Pro12Ala variant of the PPARG gene is a risk factor for peroxisome proliferator-activated receptor-gamma/alpha agonist-induced edema in type 2 diabetic patients.

1 reference

12 December 2020

Variant of transcription factor 7-like 2 (TCF7L2) gene confers risk of type 2 diabetes

1 reference

12 December 2020

TCF7L2 polymorphisms and progression to diabetes in the Diabetes Prevention Program

1 reference

12 December 2020

Switching from insulin to oral sulfonylureas in patients with diabetes due to Kir6.2 mutations.

1 reference

12 December 2020

Identification of a null allele of CYP2C9 in an African-American exhibiting toxicity to phenytoin

1 reference

12 December 2020

Response to pioglitazone treatment is associated with the lipoprotein lipase S447X variant in subjects with type 2 diabetes mellitus.

1 reference

12 December 2020

1 reference

12 December 2020

Large-scale association studies of variants in genes encoding the pancreatic beta-cell KATP channel subunits Kir6.2 (KCNJ11) and SUR1 (ABCC8) confirm that the KCNJ11 E23K variant is associated with type 2 diabetes

1 reference

12 December 2020

Ovulatory response to treatment of polycystic ovary syndrome is associated with a polymorphism in the STK11 gene

1 reference

12 December 2020

Beta-cell ABCA1 influences insulin secretion, glucose homeostasis and response to thiazolidinedione treatment

1 reference

12 December 2020

The Arg972 variant in insulin receptor substrate-1 is associated with an increased risk of secondary failure to sulfonylurea in patients with type 2 diabetes.

1 reference

12 December 2020

SLCO1B1 variants and statin-induced myopathy--a genomewide study

1 reference

12 December 2020

Pharmacokinetics of glimepiride and cytochrome P450 2C9 genetic polymorphisms

1 reference

12 December 2020

Permanent neonatal diabetes due to mutations in KCNJ11 encoding Kir6.2: patient characteristics and initial response to sulfonylurea therapy

1 reference

12 December 2020

Involvement of organic cation transporter 1 in the lactic acidosis caused by metformin

1 reference

12 December 2020

Mechanisms by which common variants in the TCF7L2 gene increase risk of type 2 diabetes

1 reference

12 December 2020

Impact of CYP2C9 and CYP2C19 polymorphisms on tolbutamide kinetics and the insulin and glucose response in healthy volunteers

1 reference

12 December 2020

The 11482G >A polymorphism in the perilipin gene is associated with weight gain with rosiglitazone treatment in type 2 diabetes.

1 reference

12 December 2020

Effect of genetic variation in the organic cation transporter 1 (OCT1) on metformin action

1 reference

12 December 2020

Pharmacokinetics and pharmacodynamics of rosiglitazone in relation to CYP2C8 genotype

1 reference

12 December 2020

Effects of ABCA1 variants on rosiglitazone monotherapy in newly diagnosed type 2 diabetes patients.

1 reference

12 December 2020

Trimethoprim and the CYP2C8*3 allele have opposite effects on the pharmacokinetics of pioglitazone

1 reference

12 December 2020

Pharmacogenetics of tolbutamide metabolism in humans

1 reference

12 December 2020

A heterozygous activating mutation in the sulphonylurea receptor SUR1 (ABCC8) causes neonatal diabetes

1 reference

12 December 2020

Cytochrome P450 2C9 *2 and *3 polymorphisms and the dose and effect of sulfonylurea in type II diabetes mellitus.

1 reference

12 December 2020

Effects of metformin and thiazolidinediones on suppression of hepatic glucose production and stimulation of glucose uptake in type 2 diabetes: a systematic review

1 reference

12 December 2020

Identification of the human cytochromes P450 catalysing the rate-limiting pathways of gliclazide elimination

1 reference

12 December 2020

Effect of genetic variation in the organic cation transporter 1, OCT1, on metformin pharmacokinetics

1 reference

12 December 2020

Metformin is a superior substrate for renal organic cation transporter OCT2 rather than hepatic OCT1.

1 reference

12 December 2020

Effects of the type 2 diabetes-associated PPARG P12A polymorphism on progression to diabetes and response to troglitazone

1 reference

12 December 2020

Genetic variants in the epithelial sodium channel associate with oedema in type 2 diabetic patients receiving the peroxisome proliferator-activated receptor gamma agonist farglitazar

1 reference

12 December 2020

A polymorphism in the AMPKalpha2 subunit gene is associated with insulin resistance and type 2 diabetes in the Japanese population

1 reference

12 December 2020

The common PPARgamma Pro12Ala polymorphism is associated with decreased risk of type 2 diabetes

1 reference

12 December 2020

Influence of CYP2C9 and CYP2C19 genetic polymorphisms on pharmacokinetics of gliclazide MR in Chinese subjects

1 reference

12 December 2020

Sequence variation in PPARG may underlie differential response to troglitazone

1 reference

12 December 2020

Changes in insulin sensitivity in response to troglitazone do not differ between subjects with and without the common, functional Pro12Ala peroxisome proliferator-activated receptor-gamma2 gene variant: results from the Troglitazone in Prevention of

1 reference

12 December 2020

Analysis of the relationship between the Pro12Ala variant in the PPAR-gamma2 gene and the response rate to therapy with pioglitazone in patients with type 2 diabetes

1 reference

12 December 2020

Impact of CYP2C9 amino acid polymorphisms on glyburide kinetics and on the insulin and glucose response in healthy volunteers

1 reference

12 December 2020

Metformin transport by a newly cloned proton-stimulated organic cation transporter (plasma membrane monoamine transporter) expressed in human intestine

1 reference

12 December 2020

Variation in TCF7L2 influences therapeutic response to sulfonylureas: a GoDARTs study

1 reference

12 December 2020

No deterioration in glycemic control in HNF-1alpha maturity-onset diabetes of the young following transfer from long-term insulin to sulphonylureas

1 reference

12 December 2020

Tolbutamide and mephenytoin hydroxylation by human cytochrome P450s in the CYP2C subfamily

1 reference

12 December 2020

Effects of Pro12Ala polymorphism of peroxisome proliferator-activated receptor gamma2 gene on rosiglitazone response in type 2 diabetes

1 reference

12 December 2020

Common single nucleotide polymorphisms in TCF7L2 are reproducibly associated with type 2 diabetes and reduce the insulin response to glucose in nondiabetic individuals

1 reference

12 December 2020

10.1007/S11892-009-0028-3

Identifiers

DOI

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20 August 2017

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PubMed ID

19323963