(Q37424997)

20 August 2017

1 reference

title

Impact of inorganic nutrients on maintenance of genomic stability (English)

1 reference

20 August 2017

Wen-Hsing Cheng

1

1 reference

20 August 2017

publication date

1 June 2009

1 reference

Environmental and Molecular Mutagenesis

20 August 2017

published in

1 reference

20 August 2017

volume

50

1 reference

20 August 2017

issue

5

1 reference

20 August 2017

page(s)

349-360

1 reference

DNA damage from micronutrient deficiencies is likely to be a major cause of cancer

20 August 2017

cites work

1 reference

Copper uptake is required for pyrrolidine dithiocarbamate-mediated oxidation and protein level increase of p53 in cells.

21 January 2018

1 reference

Copper and genomic stability in mammals

21 January 2018

1 reference

Inhibition of Ape1 nuclease activity by lead, iron, and cadmium

21 January 2018

1 reference

Zinc concentration in esophageal biopsy specimens measured by x-ray fluorescence and esophageal cancer risk

21 January 2018

1 reference

7 January 2021

Interplay between superoxide and nitric oxide in thalassemia and Fanconi's anemia

1 reference

7 January 2021

Are vitamin and mineral deficiencies a major cancer risk?

1 reference

7 January 2021

Differential effects of toxic metal compounds on the activities of Fpg and XPA, two zinc finger proteins involved in DNA repair

1 reference

7 January 2021

Mechanism of nickel assault on the zinc finger of DNA repair protein XPA.

1 reference

7 January 2021

Dietary zinc deficiency increases the methylbenzylnitrosamine-induced formation of O6-methylguanine in the esophageal DNA of the rat.

1 reference

7 January 2021

Checking on DNA damage in S phase

1 reference

7 January 2021

DNA damage response as a candidate anti-cancer barrier in early human tumorigenesis

1 reference

7 January 2021

Oncogene-induced senescence is part of the tumorigenesis barrier imposed by DNA damage checkpoints

1 reference

7 January 2021

Glutathione peroxidase protects mice from viral-induced myocarditis.

1 reference

7 January 2021

Replacement of non-heme Fe(II) with Cu(II) in the alpha-ketoglutarate dependent DNA repair enzyme AlkB: spectroscopic characterization of the active site.

1 reference

7 January 2021

Biosynthesis of selenoproteins--an overview

1 reference

7 January 2021

Exposure to lead and the developmental origin of oxidative DNA damage in the aging brain

1 reference

7 January 2021

Molecular biology of selenium with implications for its metabolism 1

1 reference

7 January 2021

Cellular glutathione peroxidase knockout mice express normal levels of selenium-dependent plasma and phospholipid hydroperoxide glutathione peroxidases in various tissues

1 reference

7 January 2021

Cellular glutathione peroxidase is the mediator of body selenium to protect against paraquat lethality in transgenic mice

1 reference

7 January 2021

Werner syndrome protein: functions in the response to DNA damage and replication stress in S-phase.

1 reference

7 January 2021

Tissue specificity of selenoprotein gene expression in rats

1 reference

7 January 2021

Tissue zinc levels in precancerous tissue in the gastrointestinal tract of azoxymethane (AOM)-treated rats

1 reference

7 January 2021

Effects of selenium supplementation for cancer prevention in patients with carcinoma of the skin. A randomized controlled trial. Nutritional Prevention of Cancer Study Group.

1 reference

7 January 2021

Cancer in xeroderma pigmentosum and related disorders of DNA repair

1 reference

7 January 2021

Chemopreventive agents: selenium

1 reference

7 January 2021

In vivo and in vitro iron-replaced zinc finger generates free radicals and causes DNA damage

1 reference

7 January 2021

Mammalian zinc transport, trafficking, and signals

1 reference

7 January 2021

Copper storage diseases: Menkes, Wilsons, and cancer

1 reference

7 January 2021

Fibroblasts derived from Gpx1 knockout mice display senescent-like features and are susceptible to H2O2-mediated cell death

1 reference

7 January 2021

Inadequate dietary copper increases tumorigenesis in the Min mouse

1 reference

7 January 2021

Molecular and biological roles of Ape1 protein in mammalian base excision repair

1 reference

7 January 2021

Amyotrophic lateral sclerosis and structural defects in Cu,Zn superoxide dismutase

1 reference

7 January 2021

Co-ordination of DNA single strand break repair

1 reference

7 January 2021

Chemotherapeutic selectivity conferred by selenium: a role for p53-dependent DNA repair

1 reference

7 January 2021

Effect of nutritional zinc-deficiency on O6-alkylguanine-DNA-methyl-transferase activities in rat tissues.

1 reference

7 January 2021

Copper-zinc superoxide dismutase prevents the early decrease of apurinic/apyrimidinic endonuclease and subsequent DNA fragmentation after transient focal cerebral ischemia in mice

1 reference

7 January 2021

The hereditary hemochromatosis protein, HFE, inhibits iron uptake via down-regulation of Zip14 in HepG2 cells

1 reference

7 January 2021

Transcriptional induction of metallothionein-I and -II genes in the livers of Cu,Zn-superoxide dismutase knockout mice.

1 reference

7 January 2021

Antioxidant status of Fanconi anemia fibroblasts

1 reference

7 January 2021

Activation of the DNA damage checkpoint and genomic instability in human precancerous lesions

1 reference

7 January 2021

The Hallmarks of Cancer

1 reference

7 January 2021

Early steps in the DNA base excision/single-strand interruption repair pathway in mammalian cells

1 reference

7 January 2021

Phase II trial of copper depletion with tetrathiomolybdate as an antiangiogenesis strategy in patients with hormone-refractory prostate cancer.

1 reference

7 January 2021

RecQ helicases: caretakers of the genome

1 reference

7 January 2021

Zinc deficiency, DNA damage and cancer risk

1 reference

7 January 2021

Low intracellular zinc induces oxidative DNA damage, disrupts p53, NFkappa B, and AP1 DNA binding, and affects DNA repair in a rat glioma cell line

1 reference

7 January 2021

Zinc deficiency induces oxidative DNA damage and increases p53 expression in human lung fibroblasts

1 reference

7 January 2021

Mice deficient in cellular glutathione peroxidase develop normally and show no increased sensitivity to hyperoxia

1 reference

7 January 2021

Inorganic selenium sensitizes prostate cancer cells to TRAIL-induced apoptosis through superoxide/p53/Bax-mediated activation of mitochondrial pathway

1 reference

7 January 2021

Pathways of Oxidative Damage

1 reference

7 January 2021

Plasma copper and zinc levels in patients with malignant tumors of digestive organs: clinical evaluation of the C1/Zn ratio

1 reference

7 January 2021

Both selenoproteins and low molecular weight selenocompounds reduce colon cancer risk in mice with genetically impaired selenoprotein expression

1 reference

7 January 2021

Reactive oxygen species act through p38 MAPK to limit the lifespan of hematopoietic stem cells

1 reference

7 January 2021

The antioxidant function of metallothionein in the heart

1 reference

7 January 2021

Modulation of angiogenesis for cancer prevention: strategies based on antioxidants and copper deficiency

1 reference

7 January 2021

Magnesium deficiency accelerates cellular senescence in cultured human fibroblasts

1 reference

7 January 2021

Accumulation of premutagenic DNA lesions in mice defective in removal of oxidative base damage

1 reference

7 January 2021

Characterization of mammalian selenoproteomes.

1 reference

7 January 2021

Mutation accumulation in the intestine and colon of mice deficient in two intracellular glutathione peroxidases

1 reference

7 January 2021

Oxidative DNA damage induced by copper and hydrogen peroxide promotes CG-->TT tandem mutations at methylated CpG dinucleotides in nucleotide excision repair-deficient cells

1 reference

7 January 2021

Differential involvement of reactive oxygen species in apoptosis induced by two classes of selenium compounds in human prostate cancer cells.

1 reference

7 January 2021

Selenium sensitizes MCF-7 breast cancer cells to doxorubicin-induced apoptosis through modulation of phospho-Akt and its downstream substrates

1 reference

7 January 2021

The role of copper in tumour angiogenesis

1 reference

7 January 2021

Oxidative damage elicited by imbalance of free radical scavenging enzymes is associated with large-scale mtDNA deletions in aging human skin

1 reference

7 January 2021

Dissociation of the genotoxic and growth inhibitory effects of selenium

1 reference

7 January 2021

1 reference

7 January 2021

Joint effects of dietary trace metals and DNA repair capacity in lung cancer risk

1 reference

7 January 2021

Defective mitochondrial peroxiredoxin-3 results in sensitivity to oxidative stress in Fanconi anemia

1 reference

7 January 2021

Stress-induced premature senescence in hTERT-expressing ataxia telangiectasia fibroblasts.

1 reference

7 January 2021

O6-methylguanine-DNA methyltransferase protects against nitrosamine-induced hepatocarcinogenesis

1 reference

7 January 2021

Cells transfected with transferrin receptor cDNA lacking the iron regulatory domain become more sensitive to the DNA-damaging action of oxidative stress.

1 reference

7 January 2021

Inhibition of DNA replication and repair by cadmium in mammalian cells. Protective interaction of zinc

1 reference

7 January 2021

The role of double-strand break repair — insights from human genetics

1 reference

7 January 2021

Oxidant defense systems in testes from zinc-deficient rats

1 reference

7 January 2021

Oxidative stress as a multiple effector in Fanconi anaemia clinical phenotype

1 reference

7 January 2021

Oxidative stress/damage induces multimerization and interaction of Fanconi anemia proteins

1 reference

7 January 2021

The DNA-binding domain of p53 contains the four conserved regions and the major mutation hot spots

1 reference

7 January 2021

Mapping, cloning and genetic characterization of the region containing the Wilson disease gene.

1 reference

7 January 2021

Antioxidants suppress lymphoma and increase longevity in Atm-deficient mice

1 reference

7 January 2021

Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis

1 reference

7 January 2021

The role of oxygen metabolism for the pathological phenotype of Fanconi anemia

1 reference

7 January 2021

Accumulation of the oxidative base lesion 8-hydroxyguanine in DNA of tumor-prone mice defective in both the Myh and Ogg1 DNA glycosylases

1 reference

7 January 2021

Association between serum selenium and the risk of cancer

1 reference

7 January 2021

Relationship between poly(ADP-ribose) polymerase activity and DNA damage induced by zinc dithiocarbamates in mouse and rat liver

1 reference

7 January 2021

Impact of copper on the induction and repair of oxidative DNA damage, poly(ADP-ribosyl)ation and PARP-1 activity

1 reference

7 January 2021

Implication of p53 in base excision DNA repair: in vivo evidence

1 reference

7 January 2021

Selenomethionine regulation of p53 by a ref1-dependent redox mechanism

1 reference

7 January 2021

Iron chelators reduce chromosomal breaks in ataxia-telangiectasia cells

1 reference

7 January 2021

The ATM-mediated DNA-damage response: taking shape.

1 reference

7 January 2021

DNA damage induces phosphorylation of the amino terminus of p53

1 reference

7 January 2021

The consensus coding sequences of human breast and colorectal cancers

1 reference

7 January 2021

Dimethyldiselenide and methylseleninic acid generate superoxide in an in vitro chemiluminescence assay in the presence of glutathione: implications for the anticarcinogenic activity of L-selenomethionine and L-Se-methylselenocysteine

1 reference

7 January 2021

Selenium compounds have disparate abilities to impose oxidative stress and induce apoptosis

1 reference

7 January 2021

AlkB demethylases flip out in different ways

1 reference

7 January 2021

The Wilson disease gene is a copper transporting ATPase with homology to the Menkes disease gene

1 reference

7 January 2021

Effect of Dietary Zinc or Copper Deficiency on the Primary Free Radical Defense System in Rats

1 reference

7 January 2021

Iron, ferritin, and nutrition

1 reference

7 January 2021

Cellular repair of oxidatively induced DNA base lesions is defective in prostate cancer cell lines, PC-3 and DU-145.

1 reference

7 January 2021

c-Myc can induce DNA damage, increase reactive oxygen species, and mitigate p53 function: a mechanism for oncogene-induced genetic instability

1 reference

7 January 2021

Werner syndrome cells escape hydrogen peroxide-induced cell proliferation arrest

1 reference

7 January 2021

Isolation of a candidate gene for Menkes disease and evidence that it encodes a copper-transporting ATPase

1 reference

7 January 2021

The DNA replication fork in eukaryotic cells.

1 reference

7 January 2021

Metal inhibition of human N-methylpurine-DNA glycosylase activity in base excision repair

1 reference

7 January 2021

Emergence of a DNA-damage response network consisting of Fanconi anaemia and BRCA proteins

1 reference

7 January 2021

Phospholipid hydroperoxide glutathione peroxidase in various mouse organs during selenium deficiency and repletion

1 reference

7 January 2021

Zinc-induced G2/M blockage is p53 and p21 dependent in normal human bronchial epithelial cells.

1 reference

7 January 2021

Deficiencies in mouse Myh and Ogg1 result in tumor predisposition and G to T mutations in codon 12 of the K-ras oncogene in lung tumors

1 reference

7 January 2021

Inhibition of human DNA ligase I activity by zinc and cadmium and the fidelity of ligation.

1 reference

7 January 2021

The selenoprotein GPX4 is essential for mouse development and protects from radiation and oxidative damage insults

1 reference

7 January 2021

Cadmium-induced activation of stress signaling pathways, disruption of ubiquitin-dependent protein degradation and apoptosis in primary rat Sertoli cell-gonocyte cocultures.

1 reference

7 January 2021

Selenium as an anticancer nutrient: roles in cell proliferation and tumor cell invasion

1 reference

7 January 2021

Tempol protects against oxidative damage and delays epithelial tumor onset in Fanconi anemia mice

1 reference

7 January 2021

Apoptosis induced by selenomethionine and methioninase is superoxide mediated and p53 dependent in human prostate cancer cells

1 reference

7 January 2021

Identifiers

DOI

10.1002/EM.20489

1 reference

20 August 2017

1 reference