(Q37432505)

English

Oridonin ring A-based diverse constructions of enone functionality: identification of novel dienone analogues effective for highly aggressive breast cancer by inducing apoptosis.

scientific article published on 31 October 2013

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scholarly article

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27 February 2020

Oridonin ring A-based diverse constructions of enone functionality: identification of novel dienone analogues effective for highly aggressive breast cancer by inducing apoptosis (English)

1 reference

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27 February 2020

apoptotic process

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1 reference

based on heuristic

inferred from title

7

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27 February 2020

9

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27 February 2020

10

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27 February 2020

author name string

Chunyong Ding

1

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27 February 2020

Yusong Zhang

2

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27 February 2020

Haijun Chen

3

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27 February 2020

Zhengduo Yang

4

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27 February 2020

Christopher Wild

5

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27 February 2020

Na Ye

6

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27 February 2020

Ailian Xiong

8

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27 February 2020

Jia Zhou

11

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27 February 2020

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31 October 2013

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27 February 2020

Journal of Medicinal Chemistry

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27 February 2020

56

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27 February 2020

21

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27 February 2020

8814-8825

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27 February 2020

Overcoming synthetic challenges of oridonin A-ring structural diversification: regio- and stereoselective installation of azides and 1,2,3-triazoles at the C-1, C-2, or C-3 position

1 reference

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23 August 2017

Novel nitrogen-enriched oridonin analogues with thiazole-fused A-ring: protecting group-free synthesis, enhanced anticancer profile, and improved aqueous solubility

1 reference

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Plakilactones from the marine sponge Plakinastrella mamillaris. Discovery of a new class of marine ligands of peroxisome proliferator-activated receptor γ.

1 reference

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Natural products as sources of new drugs over the 30 years from 1981 to 2010

1 reference

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Treatment and care of patients with metastatic breast cancer

1 reference

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Bardoxolone methyl and kidney function in CKD with type 2 diabetes

1 reference

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23 August 2017

Oridonin: An active diterpenoid targeting cell cycle arrest, apoptotic and autophagic pathways for cancer therapeutics

1 reference

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23 August 2017

Triple-negative breast cancer: an unmet medical need

1 reference

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Pathways mediating the effects of cannabidiol on the reduction of breast cancer cell proliferation, invasion, and metastasis

1 reference

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23 August 2017

Novel therapeutic approaches to the treatment of metastatic breast cancer

1 reference

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1,5-diaryl-3-oxo-1,4-pentadienes: a case for antineoplastics with multiple targets

1 reference

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23 August 2017

Triterpenoids and rexinoids as multifunctional agents for the prevention and treatment of cancer.

1 reference

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23 August 2017

Natural products in the process of finding new drug candidates

1 reference

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23 August 2017

Apoptosis, Chemoresistance, and Breast Cancer: Insights From the MCF-7 Cell Model System

1 reference

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23 August 2017

Cyclopentenone prostaglandins: new insights on biological activities and cellular targets

1 reference

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23 August 2017

The peroxisome proliferator-activated receptor-gamma is a negative regulator of macrophage activation

1 reference

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23 August 2017

Synthesis of withanolide A, biological evaluation of its neuritogenic properties, and studies on secretase inhibition

1 reference

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6 September 2017

NF-kappab facilitates oridonin-induced apoptosis and autophagy in HT1080 cells through a p53-mediated pathway

1 reference

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14 September 2017

A role for ceramide in driving cancer cell resistance to doxorubicin.

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Synthesis and biological analysis of new curcumin analogues bearing an enhanced potential for the medicinal treatment of cancer.

1 reference

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14 September 2017

Eriocalyxin B induces apoptosis of t(8;21) leukemia cells through NF-kappaB and MAPK signaling pathways and triggers degradation of AML1-ETO oncoprotein in a caspase-3-dependent manner.

1 reference

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14 September 2017

Differential control of growth, cell cycle progression, and expression of NF-kappaB in human breast cancer cells MCF-7, MCF-10A, and MDA-MB-231 by ponicidin and oridonin, diterpenoids from the chinese herb Rabdosia rubescens

1 reference

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14 September 2017

Alpha,beta-unsaturated ketone is a core moiety of natural ligands for covalent binding to peroxisome proliferator-activated receptor gamma.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3880594

14 September 2017

Oridonin induces a caspase-independent but mitochondria- and MAPK-dependent cell death in the murine fibrosarcoma cell line L929.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3880594

14 September 2017

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1 reference

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1 reference

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26 June 2018

Role of cellular glutathione and glutathione S-transferase in the expression of alkylating agent cytotoxicity in human breast cancer cells

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26 June 2018

Cytotoxicity of sesquiterpene lactones.

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26 June 2018

Structure-activity relationships of alpha, beta-unsaturated carbonylic compounds.

1 reference

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1-p-chlorophenyl-4,4-dimethyl-5-diethylamino-1-penten-3-one hydrobromide, a sulfhydryl-specific compound which reacts irreversibly with protein thiols but reversibly with small molecular weight thiols

1 reference

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The cytostatic and cytotoxic effects of oridonin (Rubescenin), a diterpenoid from Rabdosia rubescens, on tumor cells of different lineage.

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1 reference

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2 September 2018

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1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1021/JM401248X

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27 February 2020

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27 February 2020

1 reference

Europe PubMed Central

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27 February 2020

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