(Q37457176)

English

Strong evidence of a combination polymorphism of the tyrosine kinase 2 gene and the signal transducer and activator of transcription 3 gene as a DNA-based biomarker for susceptibility to Crohn's disease in the Japanese population

scientific article published on 04 August 2009

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

Strong evidence of a combination polymorphism of the tyrosine kinase 2 gene and the signal transducer and activator of transcription 3 gene as a DNA-based biomarker for susceptibility to Crohn's disease in the Japanese population (English)

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

0 references

Crohn's disease

0 references

11

object named as

Shigeru Kohno

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

author name string

Kayoko Sato

1

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

Mizuho Shiota

2

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

Sayaka Fukuda

3

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

Eiko Iwamoto

4

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

Haruhisa Machida

5

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

Tatsuo Inamine

6

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

Shinji Kondo

7

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

Katsunori Yanagihara

8

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

Hajime Isomoto

9

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

Yohei Mizuta

10

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

Kazuhiro Tsukamoto

12

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

publication date

4 August 2009

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

Journal of Clinical Immunology

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

29

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

6

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

815-825

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

Diverse genome-wide association studies associate the IL12/IL23 pathway with Crohn Disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788098

23 August 2017

GWA studies: rewriting the story of IBD.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788098

23 August 2017

IL-23 and autoimmunity: new insights into the pathogenesis of inflammatory bowel disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788098

23 August 2017

Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788098

23 August 2017

The genetics and immunopathogenesis of inflammatory bowel disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788098

23 August 2017

Genetic determinants of ulcerative colitis include the ECM1 locus and five loci implicated in Crohn's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788098

23 August 2017

Cutting edge: NKT cells constitutively express IL-23 receptor and RORgammat and rapidly produce IL-17 upon receptor ligation in an IL-6-independent fashion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788098

23 August 2017

A second generation human haplotype map of over 3.1 million SNPs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788098

23 August 2017

Unravelling the pathogenesis of inflammatory bowel disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788098

23 August 2017

Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788098

23 August 2017

Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788098

23 August 2017

The JAK-STAT signaling pathway: input and output integration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788098

23 August 2017

iHAP--integrated haplotype analysis pipeline for characterizing the haplotype structure of genes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788098

23 August 2017

Human tyrosine kinase 2 deficiency reveals its requisite roles in multiple cytokine signals involved in innate and acquired immunity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788098

23 August 2017

A genome-wide association study identifies IL23R as an inflammatory bowel disease gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788098

23 August 2017

The IL-23/Th(17) axis: therapeutic targets for autoimmune inflammation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788098

23 August 2017

The Montreal classification of inflammatory bowel disease: controversies, consensus, and implications

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788098

23 August 2017

Signaling by IL-12 and IL-23 and the immunoregulatory roles of STAT4.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788098

23 August 2017

Inflammatory Bowel Disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788098

23 August 2017

A receptor for the heterodimeric cytokine IL-23 is composed of IL-12Rbeta1 and a novel cytokine receptor subunit, IL-23R

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788098

23 August 2017

Tyk2 plays a restricted role in IFN alpha signaling, although it is required for IL-12-mediated T cell function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788098

23 August 2017

Interleukin-6-type cytokine signalling through the gp130/Jak/STAT pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788098

23 August 2017

Molecular cloning of APRF, a novel IFN-stimulated gene factor 3 p91-related transcription factor involved in the gp130-mediated signaling pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788098

23 August 2017

Coated mesalazine (5-aminosalicylic acid) versus sulphasalazine in the treatment of active ulcerative colitis: a randomised trial

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788098

23 August 2017

tyk2, prototype of a novel class of non-receptor tyrosine kinase genes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788098

23 August 2017

Inflammatory bowel disease (2)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788098

23 August 2017

Inflammatory bowel disease (1)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788098

23 August 2017

Development of a Crohn's disease activity index. National Cooperative Crohn's Disease Study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788098

23 August 2017

IL-23/IL-17 immunity as a hallmark of Crohn's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788098

14 September 2017

Activation pattern of signal transducers and activators of transcription (STAT) factors in inflammatory bowel diseases.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788098

14 September 2017

Inflammatory bowel disease: etiology and pathogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788098

26 June 2018

Classification of inflammatory bowel disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788098

26 June 2018

Sequence variants in IL10, ARPC2 and multiple other loci contribute to ulcerative colitis susceptibility

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788098

2 September 2018

Tyk2-signaling plays an important role in host defense against Escherichia coli through IL-23-induced IL-17 production by gammadelta T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788098

2 September 2018

Replication of signals from recent studies of Crohn's disease identifies previously unknown disease loci for ulcerative colitis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788098

2 September 2018

IL-22 induces lipopolysaccharide-binding protein in hepatocytes: a potential systemic role of IL-22 in Crohn's disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788098

2 September 2018

Expression of interleukin-12-related cytokine transcripts in inflammatory bowel disease: elevated interleukin-23p19 and interleukin-27p28 in Crohn's disease but not in ulcerative colitis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788098

2 September 2018

High-resolution haplotype structure in the human genome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788098

2 September 2018

Blockade of interleukin 6 trans signaling suppresses T-cell resistanceagainst apoptosis in chronic intestinal inflammation: Evidence in Crohn diseaseand experimental colitis in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788098

3 December 2018

Haplotype tagging for the identification of common disease genes

1 reference

https://pubmed.ncbi.nlm.nih.gov/19653082

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Both IL-12p70 and IL-23 are synthesized during active Crohn's disease and are down-regulated by treatment with anti-IL-12 p40 monoclonal antibody

1 reference

https://pubmed.ncbi.nlm.nih.gov/19653082

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S10875-009-9320-X

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

ResearchGate publication ID

0 references

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