(Q37489925)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19456270%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

review article

1 reference

title

Targeting ASK1 in ER stress-related neurodegenerative diseases (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19456270%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

1 reference

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19456270%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

Kengo Homma

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19456270%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

Hideki Nishitoh

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19456270%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

author name string

Kazumi Katagiri

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19456270%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

language of work or name

English

0 references

publication date

1 June 2009

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19456270%20AND%20SRC:MED&resulttype=core&format=json

Expert Opinion on Therapeutic Targets

28 January 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19456270%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

volume

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19456270%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

issue

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19456270%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

page(s)

653-664

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19456270%20AND%20SRC:MED&resulttype=core&format=json

Endoplasmic reticulum stress signaling in disease

28 January 2020

cites work

1 reference

https://api.crossref.org/works/10.1517%2F14728220902980249

Cell death and endoplasmic reticulum stress: disease relevance and therapeutic opportunities

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220902980249

The endoplasmic reticulum and the unfolded protein response

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220902980249

Induction of apoptosis by ASK1, a mammalian MAPKKK that activates SAPK/JNK and p38 signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220902980249

ALS-linked mutant SOD1 induces ER stress- and ASK1-dependent motor neuron death by targeting Derlin-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220902980249

ASK1 is essential for endoplasmic reticulum stress-induced neuronal cell death triggered by expanded polyglutamine repeats

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220902980249

Dynamic interaction of BiP and ER stress transducers in the unfolded-protein response

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220902980249

On the mechanism of sensing unfolded protein in the endoplasmic reticulum

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220902980249

The unfolded protein response: a stress signaling pathway critical for health and disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220902980249

Decay of endoplasmic reticulum-localized mRNAs during the unfolded protein response.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220902980249

Substrate-specific translocational attenuation during ER stress defines a pre-emptive quality control pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220902980249

An integrated stress response regulates amino acid metabolism and resistance to oxidative stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220902980249

ATF6alpha optimizes long-term endoplasmic reticulum function to protect cells from chronic stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220902980249

A stress response pathway from the endoplasmic reticulum to the nucleus requires a novel bifunctional protein kinase/endoribonuclease (Ire1p) in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220902980249

Cloning of mammalian Ire1 reveals diversity in the ER stress responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220902980249

Derlin-2 and Derlin-3 are regulated by the mammalian unfolded protein response and are required for ER-associated degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220902980249

ERAD: the long road to destruction

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220902980249

Retro-translocation of proteins from the endoplasmic reticulum into the cytosol

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220902980249

Molecular chaperones in the yeast endoplasmic reticulum maintain the solubility of proteins for retrotranslocation and degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220902980249

Export of a cysteine-free misfolded secretory protein from the endoplasmic reticulum for degradation requires interaction with protein disulfide isomerase

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220902980249

A novel ER alpha-mannosidase-like protein accelerates ER-associated degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220902980249

ERdj5 is required as a disulfide reductase for degradation of misfolded proteins in the ER

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220902980249

The AAA ATPase Cdc48/p97 and its partners transport proteins from the ER into the cytosol

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220902980249

Real-time fluorescence detection of ERAD substrate retrotranslocation in a mammalian in vitro system.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220902980249

Posttranslational protein translocation across the membrane of the endoplasmic reticulum.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220902980249

Structural insight into the protein translocation channel

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220902980249

The engagement of Sec61p in the ER dislocation process

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220902980249

A membrane protein complex mediates retro-translocation from the ER lumen into the cytosol

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220902980249

A membrane protein required for dislocation of misfolded proteins from the ER

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220902980249

Multiprotein complexes that link dislocation, ubiquitination, and extraction of misfolded proteins from the endoplasmic reticulum membrane

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220902980249

Recruitment of the p97 ATPase and ubiquitin ligases to the site of retrotranslocation at the endoplasmic reticulum membrane

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220902980249

Survival and apoptosis signals in ER stress: the role of protein kinases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220902980249

Roles of CHOP/GADD153 in endoplasmic reticulum stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220902980249

Generating disulfides enzymatically: reaction products and electron acceptors of the endoplasmic reticulum thiol oxidase Ero1p

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220902980249

There is more to life and death than mitochondria: Bcl-2 proteins at the endoplasmic reticulum

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220902980249

Bcl-2 on the endoplasmic reticulum: protecting the mitochondria from a distance

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220902980249

The endoplasmic reticulum in apoptosis and autophagy: role of the BCL-2 protein family.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220902980249

BH3-only proteins that bind pro-survival Bcl-2 family members fail to induce apoptosis in the absence of Bax and Bak

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220902980249

Proapoptotic BAX and BAK: a requisite gateway to mitochondrial dysfunction and death

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220902980249

Cross-talk between two cysteine protease families. Activation of caspase-12 by calpain in apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220902980249

Different subcellular distribution of caspase-3 and caspase-7 following Fas-induced apoptosis in mouse liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220902980249

Amyloid beta induces neuronal cell death through ROS-mediated ASK1 activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220902980249

Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-beta

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220902980249

Involvement of caspase-4 in endoplasmic reticulum stress-induced apoptosis and Abeta-induced cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220902980249

ASK1 is essential for JNK/SAPK activation by TRAF2

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220902980249

Requirement of reactive oxygen species-dependent activation of ASK1-p38 MAPK pathway for extracellular ATP-induced apoptosis in macrophage.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220902980249

Involvement of ASK1 in Ca2+-induced p38 MAP kinase activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220902980249

Activation of apoptosis signal-regulating kinase 1 (ASK1) by the adapter protein Daxx

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220902980249

Mammalian thioredoxin is a direct inhibitor of apoptosis signal-regulating kinase (ASK) 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220902980249

Role of apoptosis signal-regulating kinase in regulation of the c-Jun N-terminal kinase pathway and apoptosis in sympathetic neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220902980249

Execution of Apoptosis Signal-regulating Kinase 1 (ASK1)-induced Apoptosis by the Mitochondria-dependent Caspase Activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220902980249

Oxidation-triggered c-Jun N-terminal kinase (JNK) and p38 mitogen-activated protein (MAP) kinase pathways for apoptosis in human leukaemic cells stimulated by epigallocatechin-3-gallate (EGCG): a distinct pathway from those of chemically induced and

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220902980249

Thioredoxin and TRAF family proteins regulate reactive oxygen species-dependent activation of ASK1 through reciprocal modulation of the N-terminal homophilic interaction of ASK1

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220902980249

Recruitment of tumor necrosis factor receptor-associated factor family proteins to apoptosis signal-regulating kinase 1 signalosome is essential for oxidative stress-induced cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220902980249

Coupling of stress in the ER to activation of JNK protein kinases by transmembrane protein kinase IRE1

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220902980249

JNK-mediated BIM phosphorylation potentiates BAX-dependent apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220902980249

BCL-2 is phosphorylated and inactivated by an ASK1/Jun N-terminal protein kinase pathway normally activated at G(2)/M.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220902980249

Phosphorylation and inactivation of myeloid cell leukemia 1 by JNK in response to oxidative stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220902980249

Stress-induced phosphorylation and activation of the transcription factor CHOP (GADD153) by p38 MAP Kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220902980249

Amyotrophic lateral sclerosis. unfolding the toxicity of the misfolded

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220902980249

Induction of the unfolded protein response in familial amyotrophic lateral sclerosis and association of protein-disulfide isomerase with superoxide dismutase 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220902980249

Spinal cord endoplasmic reticulum stress associated with a microsomal accumulation of mutant superoxide dismutase-1 in an ALS model

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220902980249

Mutant SOD1 linked to familial amyotrophic lateral sclerosis, but not wild-type SOD1, induces ER stress in COS7 cells and transgenic mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220902980249

Motoneuron death triggered by a specific pathway downstream of Fas. potentiation by ALS-linked SOD1 mutations.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220902980249

Activation of the stress-activated MAP kinase, p38, but not JNK in cortical motor neurons during early presymptomatic stages of amyotrophic lateral sclerosis in transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220902980249

Activation of the p38MAPK cascade is associated with upregulation of TNF alpha receptors in the spinal motor neurons of mouse models of familial ALS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220902980249

Protein precipitation: a common etiology in neurodegenerative disorders?

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220902980249

Polyglutamine disease and neuronal cell death.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220902980249

Identification of ter94, Drosophila VCP, as a modulator of polyglutamine-induced neurodegeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220902980249

VCP/p97 in abnormal protein aggregates, cytoplasmic vacuoles, and cell death, phenotypes relevant to neurodegeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220902980249

Impaired ERAD and ER stress are early and specific events in polyglutamine toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220902980249

ASK1 and MAP2K6 as modifiers of age at onset in Huntington's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220902980249

Presenilin-1 mutations downregulate the signalling pathway of the unfolded-protein response

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220902980249

Disturbed activation of endoplasmic reticulum stress transducers by familial Alzheimer's disease-linked presenilin-1 mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220902980249

An RNA-dependent protein kinase is involved in tunicamycin-induced apoptosis and Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220902980249

A novel polymorphism in SEL1L confers susceptibility to Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220902980249

Hydrogen peroxide mediates amyloid beta protein toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220902980249

A model for beta-amyloid aggregation and neurotoxicity based on free radical generation by the peptide: relevance to Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220902980249

Inhibition of PC12 cell redox activity is a specific, early indicator of the mechanism of beta-amyloid-mediated cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220902980249

Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220902980249

Familial Parkinson disease gene product, parkin, is a ubiquitin-protein ligase

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220902980249

Parkin suppresses unfolded protein stress-induced cell death through its E3 ubiquitin-protein ligase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220902980249

CHIP is associated with Parkin, a gene responsible for familial Parkinson's disease, and enhances its ubiquitin ligase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220902980249

An unfolded putative transmembrane polypeptide, which can lead to endoplasmic reticulum stress, is a substrate of Parkin

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220902980249

Parkin negatively regulates JNK pathway in the dopaminergic neurons of Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220902980249

Neurotoxin-induced cell death in neuronal PC12 cells is mediated by induction of apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220902980249

Chronic systemic pesticide exposure reproduces features of Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220902980249

Mutations in the DJ-1 gene associated with autosomal recessive early-onset parkinsonism

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220902980249

DJ-1 has a role in antioxidative stress to prevent cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220902980249

Interaction of DJ-1 with Daxx inhibits apoptosis signal-regulating kinase 1 activity and cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220902980249

Chemical biology investigation of cell death pathways activated by endoplasmic reticulum stress reveals cytoprotective modulators of ASK1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220902980249

ASK1 is required for sustained activations of JNK/p38 MAP kinases and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220902980249

10.1517/14728220902980249

21 January 2018

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19456270%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

1 reference