(Q34375535)

1 August 2017

Amyloid beta induces neuronal cell death through ROS-mediated ASK1 activation (English)

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1 August 2017

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K Takeda

6

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Hidenori Ichijō

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H Ichijo

11

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author name string

H Kadowaki

1

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1 August 2017

H Nishitoh

2

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1 August 2017

F Urano

3

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1 August 2017

C Sadamitsu

4

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1 August 2017

A Matsuzawa

5

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1 August 2017

H Masutani

7

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1 August 2017

J Yodoi

8

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1 August 2017

Y Urano

9

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1 August 2017

T Nagano

10

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1 August 2017

1 January 2005

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Cell Death & Differentiation

1 August 2017

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1 August 2017

12

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1 August 2017

1

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1 August 2017

19-24

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https://scigraph.springernature.com/pub.10.1038/sj.cdd.4401528

1 August 2017

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cites work

Translating cell biology into therapeutic advances in Alzheimer's disease

1 reference

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7 January 2021

Mechanisms of neuronal degeneration in Alzheimer's disease

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4401528

7 January 2021

Alzheimer's disease results from the cerebral accumulation and cytotoxicity of amyloid beta-protein

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7 January 2021

Activation of caspase-3 in single neurons and autophagic granules of granulovacuolar degeneration in Alzheimer's disease. Evidence for apoptotic cell death.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401528

7 January 2021

A model for beta-amyloid aggregation and neurotoxicity based on free radical generation by the peptide: relevance to Alzheimer disease

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401528

7 January 2021

Inhibition of PC12 cell redox activity is a specific, early indicator of the mechanism of beta-amyloid-mediated cell death

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401528

7 January 2021

Hydrogen peroxide mediates amyloid beta protein toxicity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401528

7 January 2021

Different amyloidogenic peptides share a similar mechanism of neurotoxicity involving reactive oxygen species and calcium

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401528

7 January 2021

The nonfibrillar amyloid beta-peptide induces apoptotic neuronal cell death: involvement of its C-terminal fusogenic domain.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401528

7 January 2021

Inducible nitric oxide synthase in tangle-bearing neurons of patients with Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401528

7 January 2021

Neurotoxic mechanisms triggered by Alzheimer's disease-linked mutant M146L presenilin 1: involvement of NO synthase via a novel pertussis toxin target

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401528

7 January 2021

Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-beta

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401528

7 January 2021

An unfolded putative transmembrane polypeptide, which can lead to endoplasmic reticulum stress, is a substrate of Parkin

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401528

7 January 2021

ASK1 is essential for endoplasmic reticulum stress-induced neuronal cell death triggered by expanded polyglutamine repeats

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401528

7 January 2021

Beta-amyloid induces neuronal apoptosis via a mechanism that involves the c-Jun N-terminal kinase pathway and the induction of Fas ligand.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401528

7 January 2021

Essential role of E2-25K/Hip-2 in mediating amyloid-beta neurotoxicity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401528

7 January 2021

c-Jun contributes to amyloid beta-induced neuronal apoptosis but is not necessary for amyloid beta-induced c-jun induction.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401528

7 January 2021

Mammalian thioredoxin is a direct inhibitor of apoptosis signal-regulating kinase (ASK) 1.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401528

7 January 2021

ASK1 is essential for JNK/SAPK activation by TRAF2

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401528

7 January 2021

Induction of apoptosis by ASK1, a mammalian MAPKKK that activates SAPK/JNK and p38 signaling pathways

1 reference

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7 January 2021

Execution of Apoptosis Signal-regulating Kinase 1 (ASK1)-induced Apoptosis by the Mitochondria-dependent Caspase Activation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401528

7 January 2021

ASK1 is required for sustained activations of JNK/p38 MAP kinases and apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401528

7 January 2021

Activation of apoptosis signal-regulating kinase 1 by the stress-induced activating phosphorylation of pre-formed oligomer

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4401528

7 January 2021

The unfolded protein response and Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401528

7 January 2021

Cross-talk between two cysteine protease families. Activation of caspase-12 by calpain in apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401528

7 January 2021

Caspase-12 processing and fragment translocation into nuclei of tunicamycin-treated cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401528

7 January 2021

Involvement of p38 mitogen-activated protein kinase and apoptosis signal-regulating kinase-1 in nitric oxide-induced cell death in PC12 cells.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401528

7 January 2021

Detection and imaging of nitric oxide with novel fluorescent indicators: diaminofluoresceins.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401528

7 January 2021

Evidence that 4-hydroxynonenal mediates oxidative stress-induced neuronal apoptosis.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401528

7 January 2021

Development of novel fluorescence probes that can reliably detect reactive oxygen species and distinguish specific species

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401528

7 January 2021

Involvement of caspases in proteolytic cleavage of Alzheimer's amyloid-beta precursor protein and amyloidogenic A beta peptide formation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401528

7 January 2021

A Novel Function of Monomeric Amyloid β-Protein Serving as an Antioxidant Molecule against Metal-Induced Oxidative Damage

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401528

7 January 2021

Role of glycine-33 and methionine-35 in Alzheimer's amyloid beta-peptide 1-42-associated oxidative stress and neurotoxicity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401528

7 January 2021

Identifiers

DOI

10.1038/SJ.CDD.4401528

1 reference

Dimensions Publication ID

1 August 2017

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1 reference