(Q37494563)

20 August 2017

1 reference

title

Basement membrane proteoglycans: modulators Par Excellence of cancer growth and angiogenesis (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6712562&resulttype=core&format=json

12 May 2020

1 reference

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6712562&resulttype=core&format=json

12 May 2020

Alexander Nyström

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6712562&resulttype=core&format=json

12 May 2020

author name string

Jason J Zoeller

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6712562&resulttype=core&format=json

12 May 2020

publication date

15 May 2009

1 reference

20 August 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6712562&resulttype=core&format=json

12 May 2020

volume

27

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6712562&resulttype=core&format=json

12 May 2020

issue

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6712562&resulttype=core&format=json

12 May 2020

page(s)

503-513

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6712562&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1007/s10059-009-0069-0

12 May 2020

exact match

0 references

cites work

Suppression of autocrine and paracrine functions of basic fibroblast growth factor by stable expression of perlecan antisense cDNA

1 reference

https://api.crossref.org/works/10.1007%2FS10059-009-0069-0

The biology of perlecan: the multifaceted heparan sulphate proteoglycan of basement membranes and pericellular matrices

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10059-009-0069-0

Novel fibrogenic pathways are activated in response to endothelial apoptosis: implications in the pathophysiology of systemic sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10059-009-0069-0

Increased angiogenic response in aortic explants of collagen XVIII/endostatin-null mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10059-009-0069-0

The alpha(1)beta(1) and alpha(2)beta(1) integrins provide critical support for vascular endothelial growth factor signaling, endothelial cell migration, and tumor angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10059-009-0069-0

Agrin is a major heparan sulfate proteoglycan accumulating in Alzheimer's disease brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10059-009-0069-0

Endostatin induces endothelial cell apoptosis

21 January 2018

1 reference

12 December 2020

Agrin in Alzheimer's disease: altered solubility and abnormal distribution within microvasculature and brain parenchyma

1 reference

12 December 2020

Human perlecan immunopurified from different endothelial cell sources has different adhesive properties for vascular cells.

1 reference

12 December 2020

Perlecan is essential for cartilage and cephalic development

1 reference

12 December 2020

Perlecan maintains the integrity of cartilage and some basement membranes

1 reference

12 December 2020

Fibroblast growth factor-2.

1 reference

12 December 2020

The protein core of the proteoglycan perlecan binds specifically to fibroblast growth factor-7

1 reference

12 December 2020

Adenovirus-mediated gene transfer of endostatin in vivo results in high level of transgene expression and inhibition of tumor growth and metastases

1 reference

12 December 2020

Perlecan heparan sulfate proteoglycan: a novel receptor that mediates a distinct pathway for ligand catabolism

1 reference

12 December 2020

Perlecan is required to inhibit thrombosis after deep vascular injury and contributes to endothelial cell-mediated inhibition of intimal hyperplasia

1 reference

12 December 2020

Collagen XVIII/endostatin structure and functional role in angiogenesis

1 reference

12 December 2020

Generation and degradation of human endostatin proteins by various proteinases

1 reference

12 December 2020

Fibroblast growth factor-binding protein is a novel partner for perlecan protein core

1 reference

12 December 2020

Interaction of endostatin with integrins implicated in angiogenesis

1 reference

12 December 2020

Oligomerization-dependent regulation of motility and morphogenesis by the collagen XVIII NC1/endostatin domain

1 reference

12 December 2020

Antiangiogenesis signals by endostatin.

1 reference

12 December 2020

Distinct roles of nerve and muscle in postsynaptic differentiation of the neuromuscular synapse

1 reference

12 December 2020

Cell surface glypicans are low-affinity endostatin receptors

1 reference

12 December 2020

Vascular localization of heparan sulfate proteoglycans in retinas of patients with diabetes mellitus and in VEGF-induced retinopathy using domain-specific antibodies

1 reference

12 December 2020

Heparan sulfate proteoglycans: heavy hitters in the angiogenesis arena

1 reference

12 December 2020

A role for the perlecan protein core in the activation of the keratinocyte growth factor receptor

1 reference

12 December 2020

High serum endostatin levels in Down syndrome: implications for improved treatment and prevention of solid tumours

1 reference

12 December 2020

Lack of collagen XVIII/endostatin results in eye abnormalities

1 reference

12 December 2020

Endostatin blocks vascular endothelial growth factor-mediated signaling via direct interaction with KDR/Flk-1.

1 reference

12 December 2020

Hyperplastic conotruncal endocardial cushions and transposition of great arteries in perlecan-null mice.

1 reference

12 December 2020

Molecular analysis of collagen XVIII reveals novel mutations, presence of a third isoform, and possible genetic heterogeneity in Knobloch syndrome

1 reference

12 December 2020

Mapping sites responsible for interactions of agrin with neurons.

1 reference

12 December 2020

Expression of collagen XVIII and localization of its glycosaminoglycan attachment sites

1 reference

12 December 2020

Endorepellin, a novel inhibitor of angiogenesis derived from the C terminus of perlecan

1 reference

12 December 2020

Heparan sulfate chains of perlecan are indispensable in the lens capsule but not in the kidney

1 reference

12 December 2020

Toward a human blood serum proteome: analysis by multidimensional separation coupled with mass spectrometry

1 reference

12 December 2020

New insights into the roles of agrin

1 reference

12 December 2020

Human tumstatin and human endostatin exhibit distinct antiangiogenic activities mediated by alpha v beta 3 and alpha 5 beta 1 integrins

1 reference

12 December 2020

Agrin is a chimeric proteoglycan with the attachment sites for heparan sulfate/chondroitin sulfate located in two multiple serine-glycine clusters

1 reference

12 December 2020

Angiogenesis in collagen I requires alpha2beta1 ligation of a GFP*GER sequence and possibly p38 MAPK activation and focal adhesion disassembly

1 reference

12 December 2020

Development of the coronary arteries in a murine model of transposition of great arteries

1 reference

12 December 2020

Identification of biologic markers of the premature rupture of fetal membranes: proteomic approach

1 reference

12 December 2020

Role of perlecan in skeletal development and diseases

1 reference

12 December 2020

Lack of type XVIII collagen results in anterior ocular defects

1 reference

12 December 2020

Characterization of the human type XVIII collagen gene and proteolytic processing and tissue location of the variant containing a frizzled motif

1 reference

12 December 2020

Heparanase degrades syndecan-1 and perlecan heparan sulfate: functional implications for tumor cell invasion

1 reference

12 December 2020

Collagen XVIII/endostatin is essential for vision and retinal pigment epithelial function.

1 reference

12 December 2020

Knobloch syndrome: novel mutations in COL18A1, evidence for genetic heterogeneity, and a functionally impaired polymorphism in endostatin

1 reference

12 December 2020

Redistribution of aquaporin-4 in human glioblastoma correlates with loss of agrin immunoreactivity from brain capillary basal laminae

1 reference

12 December 2020

Increased intimal hyperplasia and smooth muscle cell proliferation in transgenic mice with heparan sulfate-deficient perlecan

1 reference

12 December 2020

Apoptosis of endothelial cells triggers a caspase-dependent anti-apoptotic paracrine loop active on VSMC.

1 reference

12 December 2020

Basement membrane assembly, stability and activities observed through a developmental lens.

1 reference

12 December 2020

Endostatin's antiangiogenic signaling network

1 reference

12 December 2020

Glycosaminoglycan-dependent and -independent inhibition of neurite outgrowth by agrin

1 reference

12 December 2020

Endorepellin causes endothelial cell disassembly of actin cytoskeleton and focal adhesions through alpha2beta1 integrin.

1 reference

12 December 2020

Structurally altered basement membranes and hydrocephalus in a type XVIII collagen deficient mouse line

1 reference

12 December 2020

Impaired angiogenesis, delayed wound healing and retarded tumor growth in perlecan heparan sulfate-deficient mice

1 reference

12 December 2020

Loss of collagen XVIII enhances neovascularization and vascular permeability in atherosclerosis

1 reference

12 December 2020

BMP-1/Tolloid-like metalloproteases process endorepellin, the angiostatic C-terminal fragment of perlecan

1 reference

12 December 2020

Matrix revolutions: "tails" of basement-membrane components with angiostatic functions

1 reference

12 December 2020

Physiological role of collagen XVIII and endostatin

1 reference

12 December 2020

Endogenous inhibitors of angiogenesis.

1 reference

12 December 2020

The role of proteomics in the assessment of premature rupture of fetal membranes.

1 reference

12 December 2020

Abnormal maturation of the retinal vasculature in type XVIII collagen/endostatin deficient mice and changes in retinal glial cells due to lack of collagen types XV and XVIII.

1 reference

12 December 2020

Heparan sulfate: a complex polymer charged with biological activity

1 reference

12 December 2020

Basement membrane proteoglycans: from cellar to ceiling

1 reference

12 December 2020

Endostatin signaling and regulation of endothelial cell-matrix interactions

1 reference

12 December 2020

Biomarker discovery from pancreatic cancer secretome using a differential proteomic approach

1 reference

12 December 2020

The clinical potential of antiangiogenic fragments of extracellular matrix proteins

1 reference

12 December 2020

VEGF165-binding sites within heparan sulfate encompass two highly sulfated domains and can be liberated by K5 lyase

1 reference

12 December 2020

Perlecan knockdown in metastatic prostate cancer cells reduces heparin-binding growth factor responses in vitro and tumor growth in vivo

1 reference

12 December 2020

Endogenous stimulators and inhibitors of angiogenesis in gastrointestinal cancers: basic science to clinical application

1 reference

12 December 2020

Agrin is involved in lymphocytes activation that is mediated by α-dystroglycan

1 reference

12 December 2020

Urinary protein expression patterns in children with sleep-disordered breathing: preliminary findings.

1 reference

12 December 2020

Alpha3Na+/K+-ATPase is a neuronal receptor for agrin

1 reference

12 December 2020

Changes in perlecan during chondrocyte differentiation in the fetal bovine rib growth plate

1 reference

12 December 2020

Proteomic analysis of amniotic fluid in pregnancies with Down syndrome

1 reference

12 December 2020

Perlecan Proteolysis Induces an α2β1 Integrin- and Src Family Kinase-dependent Anti-apoptotic Pathway in Fibroblasts in the Absence of Focal Adhesion Kinase Activation

1 reference

12 December 2020

Integrin alpha2beta1 is required for regulation of murine wound angiogenesis but is dispensable for reepithelialization

1 reference

12 December 2020

Agrin, a novel basement membrane component in human and rat liver, accumulates in cirrhosis and hepatocellular carcinoma.

1 reference

12 December 2020

Activation of muscle-specific receptor tyrosine kinase and binding to dystroglycan are regulated by alternative mRNA splicing of agrin

1 reference

12 December 2020

Wound healing in the alpha2beta1 integrin-deficient mouse: altered keratinocyte biology and dysregulated matrix metalloproteinase expression

1 reference

12 December 2020

Endorepellin in vivo: targeting the tumor vasculature and retarding cancer growth and metabolism

1 reference

12 December 2020

Endorepellin, the C-terminal angiostatic module of perlecan, enhances collagen-platelet responses via the alpha2beta1-integrin receptor

1 reference

12 December 2020

Perlecan--a multifunctional extracellular proteoglycan scaffold.

1 reference

12 December 2020

Endogenous endostatin inhibits choroidal neovascularization.

1 reference

12 December 2020

Specific cleavage of agrin by neurotrypsin, a synaptic protease linked to mental retardation

1 reference

12 December 2020

Comparison of the expression of agrin, a basement membrane heparan sulfate proteoglycan, in cholangiocarcinoma and hepatocellular carcinoma

1 reference

12 December 2020

Integrin alpha2beta1 is the required receptor for endorepellin angiostatic activity

1 reference

12 December 2020

alpha2beta1 integrin expression in the tumor microenvironment enhances tumor angiogenesis in a tumor cell-specific manner

1 reference

12 December 2020

Sustained VEGF blockade results in microenvironmental sequestration of VEGF by tumors and persistent VEGF receptor-2 activation

1 reference

12 December 2020

Proteomic profiling of endorepellin angiostatic activity on human endothelial cells

1 reference

12 December 2020

Novel interactions of perlecan: unraveling perlecan's role in angiogenesis.

1 reference

12 December 2020

A central function for perlecan in skeletal muscle and cardiovascular development

1 reference

12 December 2020

Lack of collagen XVIII accelerates cutaneous wound healing, while overexpression of its endostatin domain leads to delayed healing.

1 reference

12 December 2020

Caspase-3 activation triggers extracellular cathepsin L release and endorepellin proteolysis

1 reference

12 December 2020

Muscle-wide secretion of a miniaturized form of neural agrin rescues focal neuromuscular innervation in agrin mutant mice

1 reference

12 December 2020

Diverse cell signaling events modulated by perlecan.

1 reference

12 December 2020

Lrp4 is a receptor for Agrin and forms a complex with MuSK

1 reference

12 December 2020

Coincident pre- and postsynaptic activation induces dendritic filopodia via neurotrypsin-dependent agrin cleavage.

1 reference

12 December 2020

Mapping the 5-50-kDa fraction of human amniotic fluid proteins by 2-DE and ESI-MS.

1 reference

12 December 2020

Identification of circulating endorepellin LG3 fragment: Potential use as a serological biomarker for breast cancer

1 reference

12 December 2020

Urinary proteomic analysis of chronic allograft nephropathy

1 reference

12 December 2020

Identification of agrin, a synaptic organizing protein from Torpedo electric organ

1 reference

12 December 2020

Perlecan, basal lamina proteoglycan, promotes basic fibroblast growth factor-receptor binding, mitogenesis, and angiogenesis

1 reference

12 December 2020

Perlecan in human bone marrow: a growth-factor-presenting, but anti-adhesive, extracellular matrix component for hematopoietic cells

1 reference

12 December 2020

Perlecan: a gem of a proteoglycan

1 reference

12 December 2020

Abnormal expression of perlecan proteoglycan in metastatic melanomas

1 reference

12 December 2020

Isolation and sequencing of cDNAs for proteins with multiple domains of Gly-Xaa-Yaa repeats identify a distinct family of collagenous proteins

1 reference

12 December 2020

Cloning of cDNA and genomic DNA encoding human type XVIII collagen and localization of the alpha 1(XVIII) collagen gene to mouse chromosome 10 and human chromosome 21.

1 reference

12 December 2020

Primary structure of the alpha 1 chain of mouse type XVIII collagen, partial structure of the corresponding gene, and comparison of the alpha 1(XVIII) chain with its homologue, the alpha 1(XV) collagen chain.

1 reference

12 December 2020

Proteoglycans of the extracellular environment: clues from the gene and protein side offer novel perspectives in molecular diversity and function

1 reference

12 December 2020

The degradation of human endothelial cell-derived perlecan and release of bound basic fibroblast growth factor by stromelysin, collagenase, plasmin, and heparanases

1 reference

12 December 2020

Defective neuromuscular synaptogenesis in agrin-deficient mutant mice

1 reference

12 December 2020

Purification and characterization of perlecan fragment in urine of end-stage renal failure patients

1 reference

12 December 2020

Endostatin: an endogenous inhibitor of angiogenesis and tumor growth

1 reference

12 December 2020

Structural and functional characterization of the human perlecan gene promoter. Transcriptional activation by transforming growth factor-beta via a nuclear factor 1-binding element

1 reference

12 December 2020

A role for perlecan in the suppression of growth and invasion in fibrosarcoma cells

1 reference

12 December 2020

Developmental expression of perlecan during murine embryogenesis

1 reference

12 December 2020

Agrin is a high-affinity binding protein of dystroglycan in non-muscle tissue

1 reference

12 December 2020

Electron microscopic structure of agrin and mapping of its binding site in laminin-1

1 reference

12 December 2020

Suppression of invasive behavior of melanoma cells by stable expression of anti-sense perlecan cDNA.

1 reference

12 December 2020

Complete primary structure of two variant forms of human type XVIII collagen and tissue-specific differences in the expression of the corresponding transcripts.

1 reference

12 December 2020

Primary structure and high expression of human agrin in basement membranes of adult lung and kidney

1 reference

12 December 2020

Structure, function and tissue forms of the C-terminal globular domain of collagen XVIII containing the angiogenesis inhibitor endostatin

1 reference

12 December 2020

Collagen XVIII is a basement membrane heparan sulfate proteoglycan

1 reference

12 December 2020

Matrix proteoglycans: from molecular design to cellular function

1 reference

12 December 2020

Antisense targeting of perlecan blocks tumor growth and angiogenesis in vivo

1 reference

12 December 2020

Interaction of endostatin with integrins implicated in angiogenesis

1 reference

12 December 2020

10.1007/S10059-009-0069-0

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6712562&resulttype=core&format=json

12 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6712562&resulttype=core&format=json

12 May 2020

1 reference