(Q37511710)

20 August 2017

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title

Transcription factories: gene expression in unions? (English)

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20 August 2017

2

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20 August 2017

Heidi Sutherland

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publication date

1 July 2009

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20 August 2017

published in

Nature Reviews Genetics

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20 August 2017

volume

10

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20 August 2017

issue

7

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20 August 2017

page(s)

457-466

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https://scigraph.springernature.com/pub.10.1038/nrg2592

20 August 2017

exact match

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cites work

Transcription factories: quantitative studies of nanostructures in the mammalian nucleus

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Regional specialization in human nuclei: visualization of discrete sites of transcription by RNA polymerase III.

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Association between active genes occurs at nuclear speckles and is modulated by chromatin environment

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Lack of bystander activation shows that localization exterior to chromosome territories is not sufficient to up-regulate gene expression

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Active genes dynamically colocalize to shared sites of ongoing transcription

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Different populations of RNA polymerase II in living mammalian cells.

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RNA polymerase II activity is located on the surface of protein-rich transcription factories

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Myc dynamically and preferentially relocates to a transcription factory occupied by Igh

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Transcription factories are nuclear subcompartments that remain in the absence of transcription

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Transcription-dependent redistribution of the large subunit of RNA polymerase II to discrete nuclear domains

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Splicing speckles are not reservoirs of RNA polymerase II, but contain an inactive form, phosphorylated on serine2 residues of the C-terminal domain

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Site of transcription of ribosomal RNA and intranucleolar structure in HeLa cells

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12 December 2020

GATA transcription factors associate with a novel class of nuclear bodies in erythroblasts and megakaryocytes

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Does Saccharomyces need an organized nucleolus?

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12 December 2020

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12 December 2020

Mammalian cell lines expressing functional RNA polymerase II tagged with the green fluorescent protein

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12 December 2020

Active RNA polymerases are localized within discrete transcription "factories' in human nuclei

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12 December 2020

Identifiers

DOI

10.1038/NRG2592

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Dimensions Publication ID

20 August 2017

1043449587

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