(Q37523991)

20 August 2017

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title

Current approaches with the glutamatergic system as targets in the treatment of neuropathic pain (English)

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ORCID Public Data File 2021

20 August 2017

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author name string

Perumal Yogeeswari

1

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20 August 2017

Arvind Semwal

2

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20 August 2017

Ramkumar Mishra

3

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20 August 2017

Dharmarajan Sriram

4

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20 August 2017

language of work or name

English

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publication date

1 August 2009

1 reference

Expert Opinion on Therapeutic Targets

20 August 2017

published in

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20 August 2017

volume

13

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20 August 2017

issue

8

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20 August 2017

page(s)

925-943

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Emerging drugs in neuropathic pain

20 August 2017

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Glutamate receptors and nociception: implications for the drug treatment of pain

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Glutamate receptors and pain

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A cure for wind up: NMDA receptor antagonists as potential analgesics

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Pharmacological agents acting at subtypes of metabotropic glutamate receptors

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NMDA receptor subunits: function and pharmacology.

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Ionotropic glutamate receptors are expressed in GABAergic terminals in the rat superficial dorsal horn

21 January 2018

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Presynaptic regulation of the inhibitory transmission by GluR5-containing kainate receptors in spinal substantia gelatinosa

21 January 2018

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Treatment of Allergic Rhinitis: H1-Antihistamines and Intranasal Steroids

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Peripheral metabotropic glutamate receptors as drug targets for pain relief

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Characterisation of mGluRs which modulate nociception in the PAG of the mouse

21 January 2018

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Altered spinal arachidonic acid turnover after peripheral nerve injury regulates regional glutamate concentration and neuropathic pain behaviors in rats

21 January 2018

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Glutamate uptake is attenuated in spinal deep dorsal and ventral horn in the rat spinal nerve ligation model

21 January 2018

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Glutamate carboxypeptidase II (NAALADase) inhibition as a novel therapeutic strategy

21 January 2018

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NAAG peptidase inhibitors and their potential for diagnosis and therapy

21 January 2018

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Analgesic effect of intravenous ketamine in cancer patients on morphine therapy: a randomized, controlled, double-blind, crossover, double-dose study

21 January 2018

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Beneficial effect of low-dose ketamine addition to epidural administration of morphine-bupivacaine mixture for cancer pain in two cases.

21 January 2018

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Dextromethorphan and quinidine in adult patients with uncontrolled painful diabetic peripheral neuropathy: a 29-day, multicenter, open-label, dose-escalation study

21 January 2018

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Dextromethorphan mitigates phantom pain in cancer amputees

21 January 2018

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A randomized, controlled trial of high-dose dextromethorphan in facial neuralgias.

21 January 2018

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21 January 2018

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Memantine is a clinically well tolerated N-methyl-D-aspartate (NMDA) receptor antagonist--a review of preclinical data

21 January 2018

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A placebo-controlled randomized crossover trial of the N-methyl-D-aspartic acid receptor antagonist, memantine, in patients with chronic phantom limb pain

21 January 2018

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Efficacy of the NMDA-receptor antagonist memantine in patients with chronic phantom limb pain--results of a randomized double-blinded, placebo-controlled trial

21 January 2018

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A placebo-controlled study of memantine for the treatment of human immunodeficiency virus-associated sensory neuropathy

21 January 2018

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Successful relief of hip joint pain by percutaneous radiofrequency nerve thermocoagulation in a patient with contraindications for hip arthroplasty

21 January 2018

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Attenuation of hyperalgesia by LY235959, a competitive N-methyl-D-aspartate receptor antagonist

21 January 2018

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Agmatine reverses pain induced by inflammation, neuropathy, and spinal cord injury

21 January 2018

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Antinociceptive activity of the N-methyl-D-aspartate receptor antagonist N-(2-Indanyl)-glycinamide hydrochloride (CHF3381) in experimental models of inflammatory and neuropathic pain

21 January 2018

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21 January 2018

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Selective NMDA NR2B antagonists induce antinociception without motor dysfunction: correlation with restricted localisation of NR2B subunit in dorsal horn.

21 January 2018

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21 January 2018

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Brain but not spinal NR2B receptor is responsible for the anti-allodynic effect of an NR2B subunit-selective antagonist CP-101,606 in a rat chronic constriction injury model

21 January 2018

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A randomized, double-blind, placebo-controlled trial of a glycine antagonist in neuropathic pain

21 January 2018

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GV196771A, an NMDA receptor/glycine site antagonist, attenuates mechanical allodynia in neuropathic rats and reduces tolerance induced by morphine in mice

21 January 2018

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ACEA-1328, an NMDA receptor antagonist, increases the potency of morphine and U50,488H in the tail flick test in mice

21 January 2018

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The glycine/NMDA receptor antagonist (+)-HA966 enhances the peripheral effect of morphine in neuropathic rats

21 January 2018

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21 January 2018

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Antiallodynic effects of NMDA glycine(B) antagonists in neuropathic pain: possible peripheral mechanisms

21 January 2018

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21 January 2018

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Spread of excitation across modality borders in spinal dorsal horn of neuropathic rats

21 January 2018

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Behavioural effects of the novel AMPA/GluR5 selective receptor antagonist NS1209 after systemic administration in animal models of experimental pain

21 January 2018

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SYM-2081 a kainate receptor antagonist reduces allodynia and hyperalgesia in a freeze injury model of neuropathic pain.

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Antinociceptive profile of a selective metabotropic glutamate receptor 1 antagonist YM-230888 in chronic pain rodent models.

21 January 2018

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mGluR1 and mGluR5 antagonists in the amygdala inhibit different components of audible and ultrasonic vocalizations in a model of arthritic pain

21 January 2018

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Assessing the role of metabotropic glutamate receptor 5 in multiple nociceptive modalities

21 January 2018

1 reference

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Glutamate receptor ligands attenuate allodynia and hyperalgesia and potentiate morphine effects in a mouse model of neuropathic pain

21 January 2018

1 reference

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The antinociceptive and anxiolytic-like effects of the metabotropic glutamate receptor 5 (mGluR5) antagonists, MPEP and MTEP, and the mGluR1 antagonist, LY456236, in rodents: a comparison of efficacy and side-effect profiles

21 January 2018

1 reference

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Peripheral and spinal antihyperalgesic activity of SIB-1757, a metabotropic glutamate receptor (mGLUR(5)) antagonist, in experimental neuropathic pain in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903029210

Group II metabotropic glutamate receptor activation attenuates peripheral sensitization in inflammatory states

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903029210

Peripheral glutamate receptors contribute to mechanical hyperalgesia in a neuropathic pain model of the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903029210

Group III metabotropic glutamate receptors inhibit hyperalgesia in animal models of inflammation and neuropathic pain.

21 January 2018

1 reference

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A comparison of the glutamate release inhibition and anti-allodynic effects of gabapentin, lamotrigine, and riluzole in a model of neuropathic pain

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903029210

Inhibition of spinal N-acetylated-alpha-linked acidic dipeptidase produces an antinociceptive effect in the rat formalin test

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903029210

Spinal N-acetyl-alpha-linked acidic dipeptidase (NAALADase) inhibition attenuates mechanical allodynia induced by paw carrageenan injection in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903029210

Effects of NAAG peptidase inhibitor 2-PMPA in model chronic pain - relation to brain concentration

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903029210

Inhibition of glutamate carboxypeptidase II (NAALADase) protects against dynorphin A-induced ischemic spinal cord injury in rats

21 January 2018

1 reference

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The central nervous system effects, pharmacokinetics and safety of the NAALADase-inhibitor GPI 5693.

21 January 2018

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The preventive and therapeutic effects of GCPII (NAALADase) inhibition on painful and sensory diabetic neuropathy

21 January 2018

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Antinociceptive effects of N-acetylaspartylglutamate (NAAG) peptidase inhibitors ZJ-11, ZJ-17 and ZJ-43 in the rat formalin test and in the rat neuropathic pain model

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903029210

Synthesis and Biological Evaluation of Thiol-Based Inhibitors of Glutamate Carboxypeptidase II: Discovery of an Orally Active GCP II Inhibitor

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903029210

NMDA receptors as targets for drug action in neuropathic pain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903029210

Pharmacological effects of the non-competitive NMDA antagonist CNS 1102 in normal volunteers

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903029210

UPREGULATION OF SPINAL GLUTAMATE RECEPTORS IN CHRONIC PAIN

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728220903029210

10.1517/14728220903029210

21 January 2018

Identifiers

DOI

1 reference

20 August 2017

1 reference