(Q37548942)

English

Sirtuins and p53.

scientific article published on January 2009

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

21 August 2017

1 reference

Europe PubMed Central

Sirtuins and p53. (English)

1 reference

Europe PubMed Central

PubMed publication ID

21 August 2017

author name string

Ingeborg van Leeuwen

1

1 reference

Europe PubMed Central

PubMed publication ID

21 August 2017

Sonia Lain

2

1 reference

Europe PubMed Central

PubMed publication ID

21 August 2017

publication date

1 January 2009

1 reference

Europe PubMed Central

PubMed publication ID

21 August 2017

Advances in Cancer Research

1 reference

Europe PubMed Central

PubMed publication ID

21 August 2017

102

1 reference

Europe PubMed Central

PubMed publication ID

21 August 2017

171-195

1 reference

Europe PubMed Central

PubMed publication ID

21 August 2017

A role for the mitochondrial deacetylase Sirt3 in regulating energy homeostasis

1 reference

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based on heuristic

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Regulation of insulin secretion by SIRT4, a mitochondrial ADP-ribosyltransferase

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Sirt1 regulates aging and resistance to oxidative stress in the heart

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2902005-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Altered sirtuin expression is associated with node-positive breast cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2902005-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Mechanism of sirtuin inhibition by nicotinamide: altering the NAD(+) cosubstrate specificity of a Sir2 enzyme

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2902005-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Human histone deacetylase SIRT2 interacts with the homeobox transcription factor HOXA10

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2902005-3

7 January 2021

based on heuristic

inferred from DOI database lookup

SirT1 gain of function increases energy efficiency and prevents diabetes in mice

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2902005-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Resveratrol improves health and survival of mice on a high-calorie diet

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2902005-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Identification of a small molecule inhibitor of Sir2p

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2902005-3

7 January 2021

based on heuristic

inferred from DOI database lookup

SIRT1 inhibition alleviates gene silencing in Fragile X mental retardation syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2902005-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Inhibition of silencing and accelerated aging by nicotinamide, a putative negative regulator of yeast sir2 and human SIRT1

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2902005-3

7 January 2021

based on heuristic

inferred from DOI database lookup

The SIRT2 deacetylase regulates autoacetylation of p300

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2902005-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Mitotic arrest and cell fate: why and how mitotic inhibition of transcription drives mutually exclusive events

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2902005-3

7 January 2021

based on heuristic

inferred from DOI database lookup

The Sir2 family of protein deacetylases

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2902005-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Sirt1 regulates insulin secretion by repressing UCP2 in pancreatic beta cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2902005-3

7 January 2021

based on heuristic

inferred from DOI database lookup

SIRT1 transgenic mice show phenotypes resembling calorie restriction

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2902005-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Mechanism of human SIRT1 activation by resveratrol

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2902005-3

7 January 2021

based on heuristic

inferred from DOI database lookup

SIRT1 deacetylation and repression of p300 involves lysine residues 1020/1024 within the cell cycle regulatory domain 1

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2902005-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Histone deacetylases in acute myeloid leukaemia show a distinctive pattern of expression that changes selectively in response to deacetylase inhibitors.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2902005-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Activation of p53 by MDM2 antagonists can protect proliferating cells from mitotic inhibitors

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2902005-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Tumor suppressor HIC1 directly regulates SIRT1 to modulate p53-dependent DNA-damage responses

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2902005-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Developmental defects and p53 hyperacetylation in Sir2 homolog (SIRT1)-deficient mice

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2902005-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Mammalian SIRT1 limits replicative life span in response to chronic genotoxic stress

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2902005-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Calorie restriction promotes mammalian cell survival by inducing the SIRT1 deacetylase

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2902005-3

7 January 2021

based on heuristic

inferred from DOI database lookup

SIRT1 interacts with p73 and suppresses p73-dependent transcriptional activity

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2902005-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Epigenetic disruption of ribosomal RNA genes and nucleolar architecture in DNA methyltransferase 1 (Dnmt1) deficient cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2902005-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Sir2 blocks extreme life-span extension.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2902005-3

7 January 2021

based on heuristic

inferred from DOI database lookup

The SIRT1 deacetylase suppresses intestinal tumorigenesis and colon cancer growth

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2902005-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Cancer-specific functions of SIRT1 enable human epithelial cancer cell growth and survival.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2902005-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Mammalian Sir2 homolog SIRT7 is an activator of RNA polymerase I transcription

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2902005-3

7 January 2021

based on heuristic

inferred from DOI database lookup

"SIRT8" expressed in thyroid cancer is actually SIRT7.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2902005-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Phylogenetic classification of prokaryotic and eukaryotic Sir2-like proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2902005-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Zyxin is a novel interacting partner for SIRT1

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2902005-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Sirt1 interacts with transducin-like enhancer of split-1 to inhibit nuclear factor kappaB-mediated transcription

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2902005-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Involvement of SIRT7 in resumption of rDNA transcription at the exit from mitosis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2902005-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Identification of a class of small molecule inhibitors of the sirtuin family of NAD-dependent deacetylases by phenotypic screening

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2902005-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Small molecule regulation of Sir2 protein deacetylases

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2902005-3

7 January 2021

based on heuristic

inferred from DOI database lookup

A metabolic throttle regulates the epigenetic state of rDNA.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2902005-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Mammalian sirtuins--emerging roles in physiology, aging, and calorie restriction

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2902005-3

7 January 2021

based on heuristic

inferred from DOI database lookup

SIRT4 inhibits glutamate dehydrogenase and opposes the effects of calorie restriction in pancreatic beta cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2902005-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Where in the cell is SIRT3?--functional localization of an NAD+-dependent protein deacetylase

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2902005-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Acetylation of Sirt2 by p300 attenuates its deacetylase activity

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2902005-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Necdin regulates p53 acetylation via Sirtuin1 to modulate DNA damage response in cortical neurons

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2902005-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Antitumor activity of a small-molecule inhibitor of human silent information regulator 2 enzymes

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2902005-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Strong expression of a longevity-related protein, SIRT1, in Bowen's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2902005-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Proteomics-based identification of differentially expressed genes in human gliomas: down-regulation of SIRT2 gene

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2902005-3

7 January 2021

based on heuristic

inferred from DOI database lookup

SIRT1 is significantly elevated in mouse and human prostate cancer.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2902005-3

7 January 2021

based on heuristic

inferred from DOI database lookup

SIRT3 interacts with the daf-16 homolog FOXO3a in the mitochondria, as well as increases FOXO3a dependent gene expression

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2902005-3

7 January 2021

based on heuristic

inferred from DOI database lookup

SIRT1 promotes DNA repair activity and deacetylation of Ku70

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2902005-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Sirt2 interacts with 14-3-3 beta/gamma and down-regulates the activity of p53

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2902005-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Rescue of embryonic lethality in Mdm2-deficient mice by absence of p53

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2902005-3

7 January 2021

based on heuristic

inferred from DOI database lookup

The SIR2/3/4 complex and SIR2 alone promote longevity in Saccharomyces cerevisiae by two different mechanisms

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2902005-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Sir2-independent life span extension by calorie restriction in yeast

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2902005-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Substrate-specific activation of sirtuins by resveratrol

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2902005-3

7 January 2021

based on heuristic

inferred from DOI database lookup

A novel chalcone polyphenol inhibits the deacetylase activity of SIRT1 and cell growth in HEK293T cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2902005-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Regulation of SIRT6 protein levels by nutrient availability

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2902005-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Cancer's molecular sweet tooth and the Warburg effect.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2902005-3

7 January 2021

based on heuristic

inferred from DOI database lookup

SIRT1 deacetylase protects against neurodegeneration in models for Alzheimer's disease and amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2902005-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Active regulator of SIRT1 cooperates with SIRT1 and facilitates suppression of p53 activity

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2902005-3

7 January 2021

based on heuristic

inferred from DOI database lookup

DBC1 is a negative regulator of SIRT1

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2902005-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Nongenotoxic p53 activation protects cells against S-phase-specific chemotherapy

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2902005-3

7 January 2021

based on heuristic

inferred from DOI database lookup

SIRT1 inhibits transforming growth factor beta-induced apoptosis in glomerular mesangial cells via Smad7 deacetylation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2902005-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Improving cancer therapy by non-genotoxic activation of p53.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2902005-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Discovery, in vivo activity, and mechanism of action of a small-molecule p53 activator.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2902005-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Cancer. p53, guardian of the genome

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2902005-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Human SIR2 deacetylates p53 and antagonizes PML/p53-induced cellular senescence

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2902005-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Salermide, a Sirtuin inhibitor with a strong cancer-specific proapoptotic effect.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2902005-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Sirtuins--novel therapeutic targets to treat age-associated diseases

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2902005-3

7 January 2021

based on heuristic

inferred from DOI database lookup

SIRT1 deacetylates and positively regulates the nuclear receptor LXR

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2902005-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Regulation of WRN protein cellular localization and enzymatic activities by SIRT1-mediated deacetylation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2902005-3

7 January 2021

based on heuristic

inferred from DOI database lookup

SirT1 inhibition reduces IGF-I/IRS-2/Ras/ERK1/2 signaling and protects neurons

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2902005-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Alcohol alters hepatic FoxO1, p53, and mitochondrial SIRT5 deacetylation function

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2902005-3

7 January 2021

based on heuristic

inferred from DOI database lookup

A fasting inducible switch modulates gluconeogenesis via activator/coactivator exchange

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2902005-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Regulation of HDM2 activity by the ribosomal protein L11

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2902005-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Mammalian Sir2 homolog SIRT3 regulates global mitochondrial lysine acetylation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2902005-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Negative control of p53 by Sir2alpha promotes cell survival under stress

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2902005-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Acetylation of p53 augments its site-specific DNA binding both in vitro and in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2902005-3

7 January 2021

based on heuristic

inferred from DOI database lookup

SIRT2 is a negative regulator of anoxia-reoxygenation tolerance via regulation of 14-3-3 zeta and BAD in H9c2 cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2902005-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Dimethyl sulfoxide to vorinostat: development of this histone deacetylase inhibitor as an anticancer drug

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2902005-3

7 January 2021

based on heuristic

inferred from DOI database lookup

SIRT1 promotes endothelium-dependent vascular relaxation by activating endothelial nitric oxide synthase

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2902005-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Evolutionarily conserved and nonconserved cellular localizations and functions of human SIRT proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2902005-3

7 January 2021

based on heuristic

inferred from DOI database lookup

SIRT6 is a histone H3 lysine 9 deacetylase that modulates telomeric chromatin

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2902005-3

7 January 2021

based on heuristic

inferred from DOI database lookup

The Sirtuin family: therapeutic targets to treat diseases of aging

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2902005-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Genomic instability and aging-like phenotype in the absence of mammalian SIRT6

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2902005-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Epigenetic control of rDNA loci in response to intracellular energy status

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2902005-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Acetylation of TAF(I)68, a subunit of TIF-IB/SL1, activates RNA polymerase I transcription

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2902005-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Discovery of indoles as potent and selective inhibitors of the deacetylase SIRT1.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2902005-3

7 January 2021

based on heuristic

inferred from DOI database lookup

SIRT1 modulating compounds from high-throughput screening as anti-inflammatory and insulin-sensitizing agents

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2902005-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Nutrient availability regulates SIRT1 through a forkhead-dependent pathway.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2902005-3

7 January 2021

based on heuristic

inferred from DOI database lookup

STAT3 inhibition of gluconeogenesis is downregulated by SirT1

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2902005-3

7 January 2021

based on heuristic

inferred from DOI database lookup

The human Sir2 ortholog, SIRT2, is an NAD+-dependent tubulin deacetylase

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2902005-3

7 January 2021

based on heuristic

inferred from DOI database lookup

SIRT1 redistribution on chromatin promotes genomic stability but alters gene expression during aging

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2902005-3

7 January 2021

based on heuristic

inferred from DOI database lookup

The flavoring agent dihydrocoumarin reverses epigenetic silencing and inhibits sirtuin deacetylases

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2902005-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Sirt1 modulates premature senescence-like phenotype in human endothelial cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2902005-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Sirtuin 2 inhibitors rescue alpha-synuclein-mediated toxicity in models of Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2902005-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Melanoma cell lines are susceptible to histone deacetylase inhibitor TSA provoked cell cycle arrest and apoptosis.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2902005-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Opposing effects of sirtuins on neuronal survival: SIRT1-mediated neuroprotection is independent of its deacetylase activity

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2902005-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Sirt1 protects against high-fat diet-induced metabolic damage

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2902005-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Sirt1 promotes fat mobilization in white adipocytes by repressing PPAR-gamma

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2902005-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Emerging roles of SIRT1 in vascular endothelial homeostasis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2902005-3

7 January 2021

based on heuristic

inferred from DOI database lookup

SIRT1 controls endothelial angiogenic functions during vascular growth

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2902005-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Inhibition of SIRT1 reactivates silenced cancer genes without loss of promoter DNA hypermethylation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2902005-3

7 January 2021

based on heuristic

inferred from DOI database lookup

The NAD biosynthesis pathway mediated by nicotinamide phosphoribosyltransferase regulates Sir2 activity in mammalian cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2902005-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Nutrient control of glucose homeostasis through a complex of PGC-1alpha and SIRT1

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2902005-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Disruption of the nucleolus mediates stabilization of p53 in response to DNA damage and other stresses

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2902005-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Phosphorylation regulates SIRT1 function.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2902005-3

7 January 2021

based on heuristic

inferred from DOI database lookup

SirT3 is a nuclear NAD+-dependent histone deacetylase that translocates to the mitochondria upon cellular stress

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2902005-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Substrates and regulation mechanisms for the human mitochondrial sirtuins Sirt3 and Sirt5

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2902005-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Structural basis of inhibition of the human NAD+-dependent deacetylase SIRT5 by suramin

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2902005-3

7 January 2021

based on heuristic

inferred from DOI database lookup

BCL11A-dependent recruitment of SIRT1 to a promoter template in mammalian cells results in histone deacetylation and transcriptional repression

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2902005-3

7 January 2021

based on heuristic

inferred from DOI database lookup

SIRT3, a mitochondrial sirtuin deacetylase, regulates mitochondrial function and thermogenesis in brown adipocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2902005-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Lack of serotonin1B receptor expression leads to age-related motor dysfunction, early onset of brain molecular aging and reduced longevity

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2902005-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Inhibition of SIRT1 catalytic activity increases p53 acetylation but does not alter cell survival following DNA damage

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2902005-3

7 January 2021

based on heuristic

inferred from DOI database lookup

p53 as a therapeutic target.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2902005-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Histone deacetylase inhibitors synergize p300 autoacetylation that regulates its transactivation activity and complex formation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2902005-3

7 January 2021

based on heuristic

inferred from DOI database lookup

The alternative product from the human CDKN2A locus, p14(ARF), participates in a regulatory feedback loop with p53 and MDM2.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2902005-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Function of the SIRT1 protein deacetylase in cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2902005-3

7 January 2021

based on heuristic

inferred from DOI database lookup

SIRT3 is a stress-responsive deacetylase in cardiomyocytes that protects cells from stress-mediated cell death by deacetylation of Ku70

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2902005-3

7 January 2021

based on heuristic

inferred from DOI database lookup

The effects of histone deacetylase inhibitors on heterochromatin: implications for anticancer therapy?

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2902005-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Acetylation is indispensable for p53 activation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2902005-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Increased dosage of a sir-2 gene extends lifespan in Caenorhabditis elegans

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2902005-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Sirt7 increases stress resistance of cardiomyocytes and prevents apoptosis and inflammatory cardiomyopathy in mice

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2902005-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Human SirT1 interacts with histone H1 and promotes formation of facultative heterochromatin

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2902005-3

7 January 2021

based on heuristic

inferred from DOI database lookup

SirT2 is a histone deacetylase with preference for histone H4 Lys 16 during mitosis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2902005-3

7 January 2021

based on heuristic

inferred from DOI database lookup

In vivo activation of the p53 pathway by small-molecule antagonists of MDM2

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2902005-3

7 January 2021

based on heuristic

inferred from DOI database lookup

hSIR2(SIRT1) functions as an NAD-dependent p53 deacetylase

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2902005-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Interactions between E2F1 and SirT1 regulate apoptotic response to DNA damage

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2902005-3

7 January 2021

based on heuristic

inferred from DOI database lookup

SIRT2 deacetylates FOXO3a in response to oxidative stress and caloric restriction

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2902005-3

7 January 2021

based on heuristic

inferred from DOI database lookup

SIRT2 suppresses adipocyte differentiation by deacetylating FOXO1 and enhancing FOXO1's repressive interaction with PPARgamma

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2902005-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Impaired DNA damage response, genome instability, and tumorigenesis in SIRT1 mutant mice

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2902005-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Interplay among BRCA1, SIRT1, and Survivin during BRCA1-associated tumorigenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2902005-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Stress-inducible regulation of heat shock factor 1 by the deacetylase SIRT1

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2902005-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Deacetylation of the retinoblastoma tumour suppressor protein by SIRT1

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2902005-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Sirtuin activators mimic caloric restriction and delay ageing in metazoans

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2902005-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Histone deacetylase inhibitors: molecular mechanisms of action

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2902005-3

7 January 2021

based on heuristic

inferred from DOI database lookup

miR-34a repression of SIRT1 regulates apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2902005-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Design and synthesis of compounds that extend yeast replicative lifespan

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2902005-3

7 January 2021

based on heuristic

inferred from DOI database lookup

SIRT1 sumoylation regulates its deacetylase activity and cellular response to genotoxic stress

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2902005-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Distinct pathways of insulin-regulated versus diabetes-regulated gene expression: an in vivo analysis in MIRKO mice

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2902005-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Modulation of NF-kappaB-dependent transcription and cell survival by the SIRT1 deacetylase

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2902005-3

7 January 2021

based on heuristic

inferred from DOI database lookup

SIRT1 regulates the function of the Nijmegen breakage syndrome protein

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2902005-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Deacetylation of cortactin by SIRT1 promotes cell migration

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2902005-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Negative regulation of the deacetylase SIRT1 by DBC1

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2902005-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Regulation of MEF2 by histone deacetylase 4- and SIRT1 deacetylase-mediated lysine modifications

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2809%2902005-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1016/S0065-230X(09)02005-3

1 reference

Europe PubMed Central

PubMed publication ID

21 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

21 August 2017

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