(Q37549749)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27994068%20AND%20SRC:MED&resulttype=core&format=json

30 March 2020

title

Resetting microbiota by Lactobacillus reuteri inhibits T reg deficiency-induced autoimmunity via adenosine A2A receptors (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27994068%20AND%20SRC:MED&resulttype=core&format=json

30 March 2020

main subject

Lactobacillus reuteri

object named as

Lactobacillus reuteri

1 reference

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27994068%20AND%20SRC:MED&resulttype=core&format=json

30 March 2020

Ting Wang

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27994068%20AND%20SRC:MED&resulttype=core&format=json

30 March 2020

Michael Ferris

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27994068%20AND%20SRC:MED&resulttype=core&format=json

30 March 2020

Christopher Taylor

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27994068%20AND%20SRC:MED&resulttype=core&format=json

30 March 2020

Dat Q Tran

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27994068%20AND%20SRC:MED&resulttype=core&format=json

30 March 2020

Fayong Luo

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27994068%20AND%20SRC:MED&resulttype=core&format=json

30 March 2020

Michael R. Blackburn

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27994068%20AND%20SRC:MED&resulttype=core&format=json

30 March 2020

Stefan Roos

15

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27994068%20AND%20SRC:MED&resulttype=core&format=json

30 March 2020

Jon Marc Rhoads

16

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27994068%20AND%20SRC:MED&resulttype=core&format=json

30 March 2020

Yuying Liu

17

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27994068%20AND%20SRC:MED&resulttype=core&format=json

30 March 2020

author name string

Thomas K Hoang

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27994068%20AND%20SRC:MED&resulttype=core&format=json

30 March 2020

Xiangjun Tian

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27994068%20AND%20SRC:MED&resulttype=core&format=json

30 March 2020

Meng Luo

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27994068%20AND%20SRC:MED&resulttype=core&format=json

30 March 2020

Jain Zhou

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27994068%20AND%20SRC:MED&resulttype=core&format=json

30 March 2020

Nina Tatevian

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27994068%20AND%20SRC:MED&resulttype=core&format=json

30 March 2020

Jose G Molina

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27994068%20AND%20SRC:MED&resulttype=core&format=json

30 March 2020

Thomas H Gomez

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27994068%20AND%20SRC:MED&resulttype=core&format=json

30 March 2020

language of work or name

English

0 references

publication date

19 December 2016

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27994068%20AND%20SRC:MED&resulttype=core&format=json

Journal of Experimental Medicine

30 March 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27994068%20AND%20SRC:MED&resulttype=core&format=json

30 March 2020

volume

214

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27994068%20AND%20SRC:MED&resulttype=core&format=json

30 March 2020

issue

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27994068%20AND%20SRC:MED&resulttype=core&format=json

30 March 2020

page(s)

107-123

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27994068%20AND%20SRC:MED&resulttype=core&format=json

describes a project that uses

30 March 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC5206500/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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23 August 2017

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23 August 2017

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Dietary modulation of the microbiome affects autoinflammatory disease

23 August 2017

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23 August 2017

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Foxp3(+) T cells regulate immunoglobulin a selection and facilitate diversification of bacterial species responsible for immune homeostasis

23 August 2017

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23 August 2017

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Lactobacillus reuteri DSM 17938 differentially modulates effector memory T cells and Foxp3+ regulatory T cells in a mouse model of necrotizing enterocolitis

23 August 2017

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23 August 2017

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The efficacy of Lactobacillus reuteri DSM 17938 in infants and children: a review of the current evidence

23 August 2017

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Exome sequencing identifies a novel FOXP3 mutation in a 2-generation family with inflammatory bowel disease

23 August 2017

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Role of the microbiota in immunity and inflammation

23 August 2017

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Oral administration of inosine produces antidepressant-like effects in mice

23 August 2017

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Inosine to increase serum and cerebrospinal fluid urate in Parkinson disease: a randomized clinical trial

23 August 2017

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The role of gut microbiota in programming the immune phenotype

23 August 2017

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Diet rapidly and reproducibly alters the human gut microbiome

23 August 2017

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Immune dysregulation, polyendocrinopathy, enteropathy, X-linked (IPEX) and IPEX-related disorders: an evolving web of heritable autoimmune diseases.

23 August 2017

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Metabolites produced by commensal bacteria promote peripheral regulatory T-cell generation

23 August 2017

1 reference

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Commensal microbe-derived butyrate induces the differentiation of colonic regulatory T cells

23 August 2017

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CD39 and CD73 in immunity and inflammation

23 August 2017

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Wiskott-Aldrich syndrome: a comprehensive review

23 August 2017

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An update on the use and investigation of probiotics in health and disease

23 August 2017

1 reference

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Lactobacillus reuteri DSM 17938 changes the frequency of Foxp3+ regulatory T cells in the intestine and mesenteric lymph node in experimental necrotizing enterocolitis

23 August 2017

1 reference

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Target identification for small bioactive molecules: finding the needle in the haystack

23 August 2017

1 reference

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The altered gut microbiome and necrotizing enterocolitis

23 August 2017

1 reference

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Anti-inflammatory effects of inosine in allergic lung inflammation in mice: evidence for the participation of adenosine A2A and A 3 receptors

23 August 2017

1 reference

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Target identification of small molecules based on chemical biology approaches

23 August 2017

1 reference

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Effects of probiotics on gut microbiota: mechanisms of intestinal immunomodulation and neuromodulation

23 August 2017

1 reference

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Interactions between the microbiota and the immune system

23 August 2017

1 reference

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Host-gut microbiota metabolic interactions

23 August 2017

1 reference

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Anti-inflammatory effects of purine nucleosides, adenosine and inosine, in a mouse model of pleurisy: evidence for the role of adenosine A2 receptors.

23 August 2017

1 reference

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The role of gut microbiota in immune homeostasis and autoimmunity

23 August 2017

1 reference

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Lactobacillus reuteri strains reduce incidence and severity of experimental necrotizing enterocolitis via modulation of TLR4 and NF-κB signaling in the intestine

23 August 2017

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Agonist-bound adenosine A2A receptor structures reveal common features of GPCR activation

23 August 2017

1 reference

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Regulatory T cells and Foxp3

23 August 2017

1 reference

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Structure of an agonist-bound human A2A adenosine receptor

23 August 2017

1 reference

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IL-2-controlled expression of multiple T cell trafficking genes and Th2 cytokines in the regulatory T cell-deficient scurfy mice: implication to multiorgan inflammation and control of skin and lung inflammation

23 August 2017

1 reference

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A critical role for regulatory T cell-mediated control of inflammation in the absence of commensal microbiota

23 August 2017

1 reference

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The immune system and the gut microbiota: friends or foes?

23 August 2017

1 reference

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Stable hematopoietic cell engraftment after low-intensity nonmyeloablative conditioning in patients with immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome

23 August 2017

1 reference

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Host-microbial symbiosis in the vertebrate gastrointestinal tract and the Lactobacillus reuteri paradigm

23 August 2017

1 reference

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Inducible Foxp3+ regulatory T-cell development by a commensal bacterium of the intestinal microbiota

23 August 2017

1 reference

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QIIME allows analysis of high-throughput community sequencing data

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5206500

Plasticity of CD4+ T cell lineage differentiation.

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5206500

Regulation of multi-organ inflammation in the regulatory T cell-deficient scurfy mice

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5206500

Adenosine A2A receptor activation inhibits T helper 1 and T helper 2 cell development and effector function.

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5206500

The novel inosine analogue, INO-2002, protects against diabetes development in multiple low-dose streptozotocin and non-obese diabetic mouse models of type I diabetes

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5206500

Human-derived probiotic Lactobacillus reuteri demonstrate antimicrobial activities targeting diverse enteric bacterial pathogens.

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5206500

Dose translation from animal to human studies revisited

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5206500

Adenosine generation catalyzed by CD39 and CD73 expressed on regulatory T cells mediates immune suppression

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5206500

Monitoring of stool microbiota in subjects with diarrhea indicates distortions in composition

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5206500

Immunomodulatory and neuroprotective effects of inosine

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5206500

Inosine protects against the development of diabetes in multiple-low-dose streptozotocin and nonobese diabetic mouse models of type 1 diabetes

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5206500

Comparison of the potency of adenosine as an agonist at human adenosine receptors expressed in Chinese hamster ovary cells

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5206500

The immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) is caused by mutations of FOXP3

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5206500

Inosine binds to A3 adenosine receptors and stimulates mast cell degranulation

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5206500

Disease in the scurfy (sf) mouse is associated with overexpression of cytokine genes

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5206500

CD4+CD8- T cells are the effector cells in disease pathogenesis in the scurfy (sf) mouse

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5206500

Fatal lymphoreticular disease in the scurfy (sf) mouse requires T cells that mature in a sf thymic environment: potential model for thymic education

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5206500

X-linked lymphoreticular disease in the scurfy (sf) mutant mouse

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5206500

The interaction of short-chain fatty acids with adipose tissue: relevance for prevention of type 2 diabetes

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5206500

Turnover of adenosine in plasma of human and dog blood

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5206500

Astra Award Lecture. Adenosine, adenosine receptors and the actions of caffeine

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5206500

Kinetic and pharmacological properties of cloned human equilibrative nucleoside transporters, ENT1 and ENT2, stably expressed in nucleoside transporter-deficient PK15 cells. Ent2 exhibits a low affinity for guanosine and cytidine but a high affinity

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5206500

Extracellular MUC3 mucin secretion follows adherence of Lactobacillus strains to intestinal epithelial cells in vitro

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5206500

Clinical heterogeneity of immunodysregulation, polyendocrinopathy, enteropathy, X-linked: pulmonary involvement as a non-classical disease manifestation

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5206500

Single centre experience of haematopoietic SCT for patients with immunodysregulation, polyendocrinopathy, enteropathy, X-linked syndrome

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5206500

Sex differences in the gut microbiome drive hormone-dependent regulation of autoimmunity.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5206500

Histamine-2 receptor blockers alter the fecal microbiota in premature infants.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5206500

Type-1 immunity drives early lethality in scurfy mice

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5206500

Proteomics plus genomics approaches in primary immunodeficiency: the case of immune dysregulation, polyendocrinopathy, enteropathy, X-linked (IPEX) syndrome.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5206500

Adenosine A2A receptors and uric acid mediate protective effects of inosine against TNBS-induced colitis in rats.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5206500

Inosine reduces pain-related behavior in mice: involvement of adenosine A1 and A2A receptor subtypes and protein kinase C pathways.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5206500

Foxo proteins cooperatively control the differentiation of Foxp3+ regulatory T cells.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5206500

Selective engraftment of donor CD4+25high FOXP3-positive T cells in IPEX syndrome after nonmyeloablative hematopoietic stem cell transplantation

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5206500

Successful bone marrow transplantation for IPEX syndrome after reduced-intensity conditioning.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5206500

The nucleotide derivatives inosine and inosinic acid inhibit intestinal absorption of mizoribine in rats

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5206500

Differential requirement for A2a and A3 adenosine receptors for the protective effect of inosine in vivo

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5206500

Inosine reduces inflammation and improves survival in a murine model of colitis

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5206500

Inosine inhibits inflammatory cytokine production by a posttranscriptional mechanism and protects against endotoxin-induced shock

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5206500

Host-Mediated Inflammation Disrupts the Intestinal Microbiota and Promotes the Overgrowth of Enterobacteriaceae

1 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1084%2FJEM.20160961

Role of commercial probiotic strains against human pathogen adhesion to intestinal mucus

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1084%2FJEM.20160961

Protective effects of inosine on mice subjected to lethal total-body ionizing irradiation

21 January 2018

1 reference

12 December 2020

Pharmacokinetics and pharmacodynamics of peldesine (BCX-34), a purine nucleoside phosphorylase inhibitor, following single and multiple oral doses in healthy volunteers

1 reference

12 December 2020

Salvage of adenosine, inosine, hypoxanthine, and adenisine by the isolated epithelium of guinea pig jejunum

1 reference

12 December 2020

Altered fecal microflora and increased fecal calprotectin in infants with colic

1 reference

12 December 2020

Identifiers

DOI

10.1084/JEM.20160961

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27994068%20AND%20SRC:MED&resulttype=core&format=json

30 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27994068%20AND%20SRC:MED&resulttype=core&format=json

30 March 2020

PubMed publication ID

27994068

1 reference