(Q37550949)

21 August 2017

Tumor-suppressor genes that escape from X-inactivation contribute to cancer sex bias (English)

1 reference

21 August 2017

1 reference

1 reference

12

Gad Getz

0 references

Rameen Beroukhim

10

object named as

Rameen Beroukhim

1 reference

21 August 2017

2

David M Weinstock

1 reference

21 August 2017

Andrew Dunford

1

1 reference

21 August 2017

Virginia Savova

3

1 reference

21 August 2017

Steven E Schumacher

4

1 reference

21 August 2017

John P Cleary

5

1 reference

21 August 2017

Akinori Yoda

6

1 reference

21 August 2017

Timothy J Sullivan

7

1 reference

21 August 2017

Julian M Hess

8

1 reference

21 August 2017

Alexander A Gimelbrant

9

1 reference

21 August 2017

Michael S Lawrence

11

1 reference

21 August 2017

Andrew A Lane

13

1 reference

21 August 2017

language of work or name

English

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publication date

21 November 2016

1 reference

21 August 2017

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21 August 2017

49

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21 August 2017

1

1 reference

21 August 2017

10-16

1 reference

https://scigraph.springernature.com/pub.10.1038/ng.3726

21 August 2017

0 references

cites work

The Molecular Signatures Database (MSigDB) hallmark gene set collection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5206905

Mutations in DDX3X Are a Common Cause of Unexplained Intellectual Disability with Gender-Specific Effects on Wnt Signaling

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5206905

Comprehensive, Integrative Genomic Analysis of Diffuse Lower-Grade Gliomas

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5206905

Human genomics. The Genotype-Tissue Expression (GTEx) pilot analysis: multitissue gene regulation in humans

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5206905

Escape from X inactivation varies in mouse tissues

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5206905

Genomic landscape of paediatric adrenocortical tumours

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5206905

The inactive X chromosome is epigenetically unstable and transcriptionally labile in breast cancer

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5206905

Mutagenesis. Smoking is associated with mosaic loss of chromosome Y.

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5206905

The H3K27me3 demethylase UTX is a gender-specific tumor suppressor in T-cell acute lymphoblastic leukemia

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5206905

Contrasting roles of histone 3 lysine 27 demethylases in acute lymphoblastic leukaemia

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5206905

Biological insights from 108 schizophrenia-associated genetic loci

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5206905

Mosaic loss of chromosome Y in peripheral blood is associated with shorter survival and higher risk of cancer

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5206905

Mammalian Y chromosomes retain widely expressed dosage-sensitive regulators

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5206905

Cellular resolution maps of X chromosome inactivation: implications for neural development, function, and disease

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5206905

Discovery and saturation analysis of cancer genes across 21 tumour types

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5206905

Analysis of expressed SNPs identifies variable extents of expression from the human inactive X chromosome

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5206905

Xist RNA is a potent suppressor of hematologic cancer in mice

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5206905

23 August 2017

Cancer statistics, 2013

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5206905

Gene survival and death on the human Y chromosome

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5206905

Cancer cells preferentially lose small chromosomes

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5206905

UTX and UTY demonstrate histone demethylase-independent function in mouse embryonic development

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5206905

X-linked H3K27me3 demethylase Utx is required for embryonic development in a sex-specific manner

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5206905

A cross-species comparison of escape from X inactivation in Eutheria: implications for evolution of X chromosome inactivation

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5206905

Frequent pathway mutations of splicing machinery in myelodysplasia

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5206905

Demographic variation in incidence of adult glioma by subtype, United States, 1992-2007.

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5206905

Genes that escape from X inactivation

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5206905

Functional impact of global rare copy number variation in autism spectrum disorders

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5206905

PHF6 mutations in T-cell acute lymphoblastic leukemia

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5206905

Systematic sequencing of renal carcinoma reveals inactivation of histone modifying genes

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5206905

Somatic mutations of the histone H3K27 demethylase gene UTX in human cancer

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5206905

Sex disparities in cancer incidence by period and age.

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5206905

Dynamic changes in paternal X-chromosome activity during imprinted X-chromosome inactivation in mice

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5206905

Large-scale population study of human cell lines indicates that dosage compensation is virtually complete

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5206905

Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5206905

X-inactivation profile reveals extensive variability in X-linked gene expression in females

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5206905

Mutations in the JARID1C gene, which is involved in transcriptional regulation and chromatin remodeling, cause X-linked mental retardation

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5206905

Molecular-clinical spectrum of the ATR-X syndrome

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5206905

Antioncogenes and human cancer

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5206905

X-chromosome inactivation in development and cancer.

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5206905

RBM5, 6, and 10 differentially regulate NUMB alternative splicing to control cancer cell proliferation

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5206905

Enigmatic sex disparities in cancer incidence

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5206905

X-chromosome inactivation: molecular mechanisms from the human perspective

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5206905

Exome sequencing identifies somatic mutations of DDX3X in natural killer/T-cell lymphoma

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5206905

Absent CNKSR2 causes seizures and intellectual, attention, and language deficits.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5206905

Origins and functional evolution of Y chromosomes across mammals

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5206905

Loss of Y-chromosome does not correlate with age at onset of head and neck carcinoma: a case-control study.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5206905

X chromosome gene expression in human tissues: male and female comparisons.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5206905

Molecular genetic evidence of Y chromosome loss in male patients with hematological disorders

1 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27869828

12 December 2020

inferred from PubMed ID database lookup

MLL2 and KDM6A mutations in patients with Kabuki syndrome

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27869828

12 December 2020

inferred from PubMed ID database lookup

Pan-cancer patterns of somatic copy number alteration

1 reference

7 January 2021

Integrative analysis of complex cancer genomics and clinical profiles using the cBioPortal

1 reference

7 January 2021

The cBio cancer genomics portal: an open platform for exploring multidimensional cancer genomics data

1 reference

7 January 2021

Evolutionarily conserved elements in vertebrate, insect, worm, and yeast genomes

1 reference

7 January 2021

Absolute quantification of somatic DNA alterations in human cancer

1 reference

7 January 2021

Assessing the significance of chromosomal aberrations in cancer: methodology and application to glioma

1 reference

7 January 2021

Mutations in G protein β subunits promote transformation and kinase inhibitor resistance

1 reference

7 January 2021

Mutations in the DDR2 kinase gene identify a novel therapeutic target in squamous cell lung cancer

1 reference

7 January 2021

Triplication of a 21q22 region contributes to B cell transformation through HMGN1 overexpression and loss of histone H3 Lys27 trimethylation

1 reference

7 January 2021

Identifiers

DOI

10.1038/NG.3726

1 reference

21 August 2017

1 reference

21 August 2017

1 reference