(Q37564269)

21 August 2017

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title

Diverse regulatory roles for lysosomal proteases in the immune response (English)

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21 August 2017

4

Colin Watts

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21 August 2017

Jeff D Colbert

1

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21 August 2017

Stephen P Matthews

series ordinal

2

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21 August 2017

Gail Miller

series ordinal

3

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21 August 2017

language of work or name

English

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publication date

1 November 2009

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European Journal of Immunology

21 August 2017

published in

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21 August 2017

volume

39

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21 August 2017

issue

11

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21 August 2017

page(s)

2955-2965

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Lysosomal cysteine and aspartic proteases are heterogeneously expressed and act redundantly to initiate human invariant chain degradation

21 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200939650

Differential regulation of the nature and functions of dendritic cells and macrophages by cathepsin E.

21 January 2018

1 reference

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Cathepsin G, and not the asparagine-specific endoprotease, controls the processing of myelin basic protein in lysosomes from human B lymphocytes

21 January 2018

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Mycobacterium bovis BCG attenuates surface expression of mature class II molecules through IL-10-dependent inhibition of cathepsin S.

21 January 2018

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https://api.crossref.org/works/10.1002%2FEJI.200939650

Identification of interleukin-8 converting enzyme as cathepsin L.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200939650

Cathepsin-L influences the expression of extracellular matrix in lymphoid organs and plays a role in the regulation of thymic output and of peripheral T cell number

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200939650

Dipeptidyl peptidase I activates neutrophil-derived serine proteases and regulates the development of acute experimental arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200939650

Papillon-Lefèvre syndrome: correlating the molecular, cellular, and clinical consequences of cathepsin C/dipeptidyl peptidase I deficiency in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200939650

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200939650

Glucocorticoids engage different signal transduction pathways to induce apoptosis in thymocytes and mature T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200939650

Cathepsin-dependent apoptosis triggered by supraoptimal activation of T lymphocytes: a possible mechanism of high dose tolerance

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200939650

Lysosomal involvement in cell death and cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200939650

The ectodomain of Toll-like receptor 9 is cleaved to generate a functional receptor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200939650

7 January 2021

Proteolytic cleavage in an endolysosomal compartment is required for activation of Toll-like receptor 9

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200939650

7 January 2021

Invariant chain structure and MHC class II function

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200939650

7 January 2021

A metalloproteinase disintegrin that releases tumour-necrosis factor-alpha from cells

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200939650

7 January 2021

Multiple proteolytic action of rat liver cathepsin B: specificities and pH-dependences of the endo- and exopeptidase activities

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200939650

7 January 2021

Multistep autoactivation of asparaginyl endopeptidase in vitro and in vivo

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200939650

7 January 2021

Biosynthetic processing of cathepsins and lysosomal degradation are abolished in asparaginyl endopeptidase-deficient mice

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200939650

7 January 2021

Decrease in macrophage antigen catabolism caused by ammonia and chloroquine is associated with inhibition of antigen presentation to T cells

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200939650

7 January 2021

Antigen recognition by H-2-restricted T cells. I. Cell-free antigen processing

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200939650

7 January 2021

Processed antigen binds to newly synthesized MHC class II molecules in antigen-specific B lymphocytes

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200939650

7 January 2021

Role for intracellular proteases in the processing and transport of class II HLA antigens

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200939650

7 January 2021

Endosomal proteases in antigen presentation

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200939650

7 January 2021

Recent advances in antigen processing and presentation

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200939650

7 January 2021

Asparagine endopeptidase can initiate the removal of the MHC class II invariant chain chaperone.

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200939650

7 January 2021

Important role of cathepsin S in generating peptides for TAP-independent MHC class I crosspresentation in vivo

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200939650

7 January 2021

Regulation of dendritic cell migration by CD74, the MHC class II-associated invariant chain

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200939650

7 January 2021

TLR ligand-induced podosome disassembly in dendritic cells is ADAM17 dependent

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200939650

7 January 2021

Major histocompatibility complex class II-associated p41 invariant chain fragment is a strong inhibitor of lysosomal cathepsin L

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200939650

7 January 2021

Inhibitory fragment from the p41 form of invariant chain can regulate activity of cysteine cathepsins in antigen presentation.

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200939650

7 January 2021

The p41 isoform of invariant chain is a chaperone for cathepsin L

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200939650

7 January 2021

Antigen presentation enhanced by the alternatively spliced invariant chain gene product p41.

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200939650

7 January 2021

Characterization of the MHC class I cross-presentation pathway for cell-associated antigens by human dendritic cells

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200939650

7 January 2021

Haematopoietic development and immunological function in the absence of cathepsin D.

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200939650

7 January 2021

The exogenous pathway for antigen presentation on major histocompatibility complex class II and CD1 molecules

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200939650

7 January 2021

An asparaginyl endopeptidase processes a microbial antigen for class II MHC presentation.

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200939650

7 January 2021

Specific role for cathepsin S in the generation of antigenic peptides in vivo

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200939650

7 January 2021

Antigen processing in the endocytic compartment

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200939650

7 January 2021

Presentation of the Goodpasture autoantigen requires proteolytic unlocking steps that destroy prominent T cell epitopes

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200939650

7 January 2021

Cathepsin E regulates the presentation of tetanus toxin C-fragment in PMA activated primary human B cells

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200939650

7 January 2021

Association of cathepsin E deficiency with development of atopic dermatitis

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200939650

7 January 2021

A role for cathepsin E in the processing of mast-cell carboxypeptidase A.

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200939650

7 January 2021

Activity and subcellular distribution of cathepsins in primary human monocytes

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200939650

7 January 2021

Differential lysosomal proteolysis in antigen-presenting cells determines antigen fate

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200939650

7 January 2021

NOX2 Controls Phagosomal pH to Regulate Antigen Processing during Crosspresentation by Dendritic Cells

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200939650

7 January 2021

Destructive potential of the aspartyl protease cathepsin D in MHC class II-restricted antigen processing.

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200939650

7 January 2021

Enhancing immunogenicity by limiting susceptibility to lysosomal proteolysis

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200939650

7 January 2021

Destructive processing by asparagine endopeptidase limits presentation of a dominant T cell epitope in MBP.

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200939650

7 January 2021

Cytokines regulate proteolysis in major histocompatibility complex class II-dependent antigen presentation by dendritic cells

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200939650

7 January 2021

In vivo priming of T cells against cryptic determinants by dendritic cells exposed to interleukin 6 and native antigen.

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200939650

7 January 2021

IL-6-STAT3 controls intracellular MHC class II alphabeta dimer level through cathepsin S activity in dendritic cells

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200939650

7 January 2021

DM determines the cryptic and immunodominant fate of T cell epitopes

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200939650

7 January 2021

Interleukin-8 processing by neutrophil elastase, cathepsin G and proteinase-3.

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200939650

7 January 2021

Evidence for a crucial role of neutrophil-derived serine proteases in the inactivation of interleukin-6 at sites of inflammation

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200939650

7 January 2021

Cathepsin B is involved in the trafficking of TNF-alpha-containing vesicles to the plasma membrane in macrophages

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200939650

7 January 2021

Thymocyte expression of cathepsin L is essential for NKT cell development

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200939650

7 January 2021

Regulation of CD1 function and NK1.1(+) T cell selection and maturation by cathepsin S.

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200939650

7 January 2021

Cathepsin L: critical role in Ii degradation and CD4 T cell selection in the thymus

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200939650

7 January 2021

Cathepsin L regulates CD4+ T cell selection independently of its effect on invariant chain: a role in the generation of positively selecting peptide ligands

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200939650

7 January 2021

An unusual specificity in the activation of neutrophil serine proteinase zymogens

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200939650

7 January 2021

Dipeptidyl peptidase I is essential for activation of mast cell chymases, but not tryptases, in mice

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200939650

7 January 2021

Dipeptidyl peptidase I is required for the processing and activation of granzymes A and B in vivo

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200939650

7 January 2021

Residual active granzyme B in cathepsin C-null lymphocytes is sufficient for perforin-dependent target cell apoptosis

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200939650

7 January 2021

In vivo inhibition of serine protease processing requires a high fractional inhibition of cathepsin C.

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200939650

7 January 2021

Cystatin F is a cathepsin C-directed protease inhibitor regulated by proteolysis

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200939650

7 January 2021

Cystatin F is secreted, but artificial modification of its C-terminus can induce its endocytic targeting

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200939650

7 January 2021

Inhibitory properties of cystatin F and its localization in U937 promonocyte cells

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200939650

7 January 2021

Structural basis of reduction-dependent activation of human cystatin F.

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200939650

7 January 2021

Glycosylation directs targeting and activation of cystatin f from intracellular and extracellular sources.

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200939650

7 January 2021

Characterization of murine cathepsin W and its role in cell-mediated cytotoxicity

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200939650

7 January 2021

Cathepsin W expressed exclusively in CD8+ T cells and NK cells, is secreted during target cell killing but is not essential for cytotoxicity in human CTLs

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200939650

7 January 2021

Serine protease cathepsin G regulates adhesion-dependent neutrophil effector functions by modulating integrin clustering

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200939650

7 January 2021

The role of cathepsin X in the migration and invasiveness of T lymphocytes

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200939650

7 January 2021

Maturation of dendritic cells depends on proteolytic cleavage by cathepsin X.

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200939650

7 January 2021

RGD-dependent binding of procathepsin X to integrin alphavbeta3 mediates cell-adhesive properties

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200939650

7 January 2021

Activation of lysosomal enzymes in virus-infected cells and its possible relationship to cytopathic effects

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200939650

7 January 2021

Lysosomal membrane permeabilization in cell death

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200939650

7 January 2021

Commitment to apoptosis in CD4(+) T lymphocytes productively infected with human immunodeficiency virus type 1 is initiated by lysosomal membrane permeabilization, itself induced by the isolated expression of the viral protein Nef

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200939650

7 January 2021

Caspase-8 is activated by cathepsin D initiating neutrophil apoptosis during the resolution of inflammation

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200939650

7 January 2021

Molecular mechanisms of activated T cell death in vivo

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200939650

7 January 2021

Serine protease inhibitor 2A is a protective factor for memory T cell development

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200939650

7 January 2021

Lysosomal destabilization contributes to apoptosis of germinal center B-lymphocytes

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200939650

7 January 2021

Apoptosis as an HIV strategy to escape immune attack

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200939650

7 January 2021

Mature cathepsin L is substantially active in the ionic milieu of the extracellular medium.

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200939650

7 January 2021

Exocytosis of active cathepsin B enzyme activity at pH 7.0, inhibition and molecular mass

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200939650

7 January 2021

A cathepsin L isoform that is devoid of a signal peptide localizes to the nucleus in S phase and processes the CDP/Cux transcription factor

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200939650

7 January 2021

Tumor necrosis factor-related apoptosis-inducing ligand activates a lysosomal pathway of apoptosis that is regulated by Bcl-2 proteins

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200939650

7 January 2021

Apoptosome-independent activation of the lysosomal cell death pathway by caspase-9.

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200939650

7 January 2021

Cathepsin K-dependent toll-like receptor 9 signaling revealed in experimental arthritis.

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200939650

7 January 2021

Cathepsins are required for Toll-like receptor 9 responses

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200939650

7 January 2021

Neuroprotective actions of PIKE-L by inhibition of SET proteolytic degradation by asparagine endopeptidase

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200939650

7 January 2021

Anaplasma phagocytophilum increases cathepsin L activity, thereby globally influencing neutrophil function

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200939650

7 January 2021

Selective targeting of lysosomal cysteine proteases with radiolabeled electrophilic substrate analogs

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200939650

7 January 2021

Development of protease inhibitors for protozoan infections

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200939650

7 January 2021

Emerging roles of proteases in tumour suppression

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200939650

7 January 2021

Identifiers

DOI

10.1002/EJI.200939650

1 reference

21 August 2017

1 reference