(Q37574065)

English

Uterus hyperplasia and increased carcinogen-induced tumorigenesis in mice carrying a targeted mutation of the Chk2 phosphorylation site in Brca1

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scholarly article

1 reference

Europe PubMed Central

21 August 2017

Uterus hyperplasia and increased carcinogen-induced tumorigenesis in mice carrying a targeted mutation of the Chk2 phosphorylation site in Brca1 (English)

1 reference

Europe PubMed Central

21 August 2017

phosphorylation

0 references

1 reference

based on heuristic

inferred from title

author name string

Sang Soo Kim

1

1 reference

Europe PubMed Central

21 August 2017

Liu Cao

2

1 reference

Europe PubMed Central

21 August 2017

Cuiling Li

3

1 reference

Europe PubMed Central

21 August 2017

Xiaoling Xu

4

1 reference

Europe PubMed Central

21 August 2017

L Julie Huber

5

1 reference

Europe PubMed Central

21 August 2017

Lewis A Chodosh

6

1 reference

Europe PubMed Central

21 August 2017

Chu-Xia Deng

7

1 reference

Europe PubMed Central

21 August 2017

language of work or name

0 references

publication date

1 November 2004

1 reference

Europe PubMed Central

21 August 2017

Molecular and Cellular Biology

1 reference

Europe PubMed Central

21 August 2017

24

1 reference

Europe PubMed Central

21 August 2017

9498-9507

1 reference

Europe PubMed Central

21 August 2017

21

1 reference

Europe PubMed Central

21 August 2017

Chk2 phosphorylation of BRCA1 regulates DNA double-strand break repair

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=522227

23 August 2017

Familial breast cancer and the hCHK2 1100delC mutation: assessing cancer risk

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=522227

23 August 2017

Chk1 and Chk2 kinases in checkpoint control and cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=522227

23 August 2017

The CHEK2 1100delC mutation identifies families with a hereditary breast and colorectal cancer phenotype

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=522227

23 August 2017

Roles of BRCA1 in DNA damage repair: a link between development and cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=522227

23 August 2017

Mediator of DNA damage checkpoint protein 1 regulates BRCA1 localization and phosphorylation in DNA damage checkpoint control

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=522227

23 August 2017

Senescence, aging, and malignant transformation mediated by p53 in mice lacking the Brca1 full-length isoform

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=522227

23 August 2017

The circadian gene Period2 plays an important role in tumor suppression and DNA damage response in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=522227

23 August 2017

Chk2-deficient mice exhibit radioresistance and defective p53-mediated transcription

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=522227

23 August 2017

Roles of BRCA1 in centrosome duplication

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=522227

23 August 2017

Low-penetrance susceptibility to breast cancer due to CHEK2(*)1100delC in noncarriers of BRCA1 or BRCA2 mutations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=522227

23 August 2017

Tumor formation in Brca1 conditional mutant mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=522227

23 August 2017

Analysis of CHK2 in vulval neoplasia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=522227

23 August 2017

Cancer susceptibility and the functions of BRCA1 and BRCA2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=522227

23 August 2017

Mutation analysis of the CHK2 gene in families with hereditary breast cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=522227

23 August 2017

Impaired DNA damage response in cells expressing an exon 11-deleted murine Brca1 variant that localizes to nuclear foci

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=522227

23 August 2017

Tumorigenesis in mice carrying a truncating Brca1 mutation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=522227

23 August 2017

Involvement of Brca1 in S-phase and G(2)-phase checkpoints after ionizing irradiation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=522227

23 August 2017

The ATM-Chk2-Cdc25A checkpoint pathway guards against radioresistant DNA synthesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=522227

23 August 2017

Lessons learned from BRCA1 and BRCA2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=522227

23 August 2017

The DNA damage response: putting checkpoints in perspective

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=522227

23 August 2017

Ataxia telangiectasia-mutated phosphorylates Chk2 in vivo and in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=522227

23 August 2017

A critical role for histone H2AX in recruitment of repair factors to nuclear foci after DNA damage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=522227

23 August 2017

Roles of BRCA1 and its interacting proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=522227

23 August 2017

ATM-dependent phosphorylation of nibrin in response to radiation exposure

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=522227

23 August 2017

hCds1-mediated phosphorylation of BRCA1 regulates the DNA damage response

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=522227

23 August 2017

DNA damage-induced activation of p53 by the checkpoint kinase Chk2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=522227

23 August 2017

Heterozygous germ line hCHK2 mutations in Li-Fraumeni syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=522227

23 August 2017

Gly369Cys mutation in mouse FGFR3 causes achondroplasia by affecting both chondrogenesis and osteogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=522227

23 August 2017

Requirement of ATM-dependent phosphorylation of brca1 in the DNA damage response to double-strand breaks

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=522227

23 August 2017

Conditional mutation of Brca1 in mammary epithelial cells results in blunted ductal morphogenesis and tumour formation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=522227

23 August 2017

Centrosome amplification and a defective G2-M cell cycle checkpoint induce genetic instability in BRCA1 exon 11 isoform-deficient cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=522227

23 August 2017

Targeted disruption of SMAD3 results in impaired mucosal immunity and diminished T cell responsiveness to TGF-beta

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=522227

23 August 2017

BRCA1 is a cell cycle-regulated nuclear phosphoprotein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=522227

23 August 2017

BRCA1 expression is induced before DNA synthesis in both normal and tumor-derived breast cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=522227

23 August 2017

Fibroblast growth factor receptor 3 is a negative regulator of bone growth

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=522227

23 August 2017

Mice lacking p21CIP1/WAF1 undergo normal development, but are defective in G1 checkpoint control

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=522227

23 August 2017

Expression of Brca1 is associated with terminal differentiation of ectodermally and mesodermally derived tissues in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=522227

23 August 2017

A strong candidate for the breast and ovarian cancer susceptibility gene BRCA1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=522227

23 August 2017

Loss of heterozygosity of BRCA1, TP53 and TCRD markers analysed in sporadic endometrial cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=522227

6 September 2017

Multiple genetic changes are associated with mammary tumorigenesis in Brca1 conditional knockout mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=522227

28 September 2017

Breast cancer susceptibility genes. BRCA1 and BRCA2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=522227

25 June 2018

Phosphorylation of serine 1387 in Brca1 is specifically required for the Atm-mediated S-phase checkpoint after ionizing irradiation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=522227

1 September 2018

Genetic interactions between tumor suppressors Brca1 and p53 in apoptosis, cell cycle and tumorigenesis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=522227

1 September 2018

p53 mediates permanent arrest over multiple cell cycles in response to gamma-irradiation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=522227

1 September 2018

Instability of simple sequence repeats in a mammalian cell line

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=522227

1 September 2018

Concomitant inactivation of p53 and Chk2 in breast cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=522227

3 December 2018

Risk of Endometrial Carcinoma Associated with BRCA Mutation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=522227

3 December 2018

Histological type-selective, tumor-predominant expression of a novel CHK1 isoform and infrequent in vivo somatic CHK2 mutation in small cell lung cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/15485917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mutation analysis of the DNA-damage checkpoint gene CHK2 in myelodysplastic syndromes and acute myeloid leukemias

1 reference

https://pubmed.ncbi.nlm.nih.gov/15485917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Murine FGFR-1 is required for early postimplantation growth and axial organization

1 reference

https://pubmed.ncbi.nlm.nih.gov/15485917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Epidemiology, prevention, and early detection of breast cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/15485917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Atm haploinsufficiency results in increased sensitivity to sublethal doses of ionizing radiation in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/15485917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mutations of the CHK2 gene are found in some osteosarcomas, but are rare in breast, lung, and ovarian tumors

1 reference

https://pubmed.ncbi.nlm.nih.gov/15485917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mutations of Chk2 in primary hematopoietic neoplasms

1 reference

https://pubmed.ncbi.nlm.nih.gov/15485917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

BRCA1 facilitates microhomology-mediated end joining of DNA double strand breaks

1 reference

https://pubmed.ncbi.nlm.nih.gov/15485917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cell cycle differences in DNA damage-induced BRCA1 phosphorylation affect its subcellular localization

1 reference

https://pubmed.ncbi.nlm.nih.gov/15485917

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1128/MCB.24.21.9498-9507.2004

1 reference

Europe PubMed Central

21 August 2017

1 reference

Europe PubMed Central

21 August 2017

1 reference

Europe PubMed Central

21 August 2017

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